Sakai Takashi 酒井貴史

Researcher Number	20624290
Other IDs
Affiliation (Current)	2025: 大分大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2021 – 2023: 大分大学, 医学部, 助教 2019: 大分大学, 医学部, 助教 2017 – 2018: 大分大学, 医学部, 客員研究員 2015 – 2016: 大分大学, 医学部, 助教 2013 – 2014: 大分大学, 医学部, 医員
Review Section/Research Field	Principal Investigator Dermatology / Basic Section 53050:Dermatology-related
Keywords	Principal Investigator アトピー性皮膚炎 / 角層pH / RANKL / 骨折 / マイクロアレイ / Flaky tail マウス / トランスクリプトーム解析 / 炎症性皮膚疾患 / Flaky-tailマウス / フィラグリン

アトピー性皮膚炎患者に生じる炎症と骨異常の予防戦略開発：RANKLを標的としてPrincipal Investigator
- Principal Investigator
  
  酒井貴史
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Oita University
Develop new therapeutic strategies for atopic dermatitis, focusing on stratum corneum pHPrincipal Investigator
- Principal Investigator
  
  Sakai Takashi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Oita University
Defective maintenance of pH of stratum corneum can induce atopic dermatitisPrincipal Investigator
- Principal Investigator
  
  Sakai Takashi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Oita University

All 2023 2022 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Fracture risks and their mechanisms in atopic dermatitis, focusing on receptor activator of nuclear factor kappa-B ligand2023
- Author(s)
  Sakai Takashi
- Journal Title
  
  Clinical and Experimental Dermatology
  
  Volume: 48 Issue: 11 Pages: 1209-1213
- DOI
  10.1093/ced/llad220
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08435
[Journal Article] アトピー性皮膚炎患者における骨折リスクと血清RANKL値の変動2023
- Author(s)
  酒井貴史
- Journal Title
  
  アレルギーの臨床
  
  Volume: 43(7) Pages: 537-539
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08435
[Journal Article] Site-specific microarray evaluation of spontaneous dermatitis in flaky tail mice2019
- Author(s)
  Takashi Sakai, Chinatsu Aoki, Yasuko Mori, Tomoko Yamate, Haruna Matsuda-Hirose, Yutaka Hatano
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: in press Issue: 12 Pages: 2554-2557.e5
- DOI
  10.1016/j.jid.2019.04.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16347
[Journal Article] Wy14643, an agonist for PPARα, down-regulates expression of TARC and RANTES in cultured human keratinocytes2017
- Author(s)
  Zhang W, Sakai T, Fujiwara S, Hatano Y
- Journal Title
  
  Experimental Dermatology
  
  Volume: 印刷中 Issue: 5 Pages: 457-459
- DOI
  10.1111/exd.13245
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461662, KAKENHI-PROJECT-25860958
[Journal Article] Betamethasone Butyrate Propionate Inhibits the Induction of Thymic Stromal Lymphopoietin in Cultured Normal Human Keratinocytes.2016
- Author(s)
  Zhang W, Sakai T, Hatano Y, Fujiwara S.
- Journal Title
  
  Ann Dermatol.
  
  Volume: 28(6) Issue: 6 Pages: 772-775
- DOI
  10.5021/ad.2016.28.6.772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860958
[Journal Article] Combined Benefits of a PAR2 Inhibitor and Stratum Corneum Acidification for Murine Atopic Dermatitis.2016
- Author(s)
  Sakai T, Hatano Y, Matsuda-Hirose H, et al.
- Journal Title
  
  J Invest Dermatol
  
  Volume: 136 Issue: 2 Pages: 538-41
- DOI
  10.1016/j.jid.2015.11.011
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01621, KAKENHI-PROJECT-25860958
[Journal Article] Knockdown of either filaggrin or loricrin increases the productions of interleukin (IL)-1α, IL-8, IL-18 and granulocyte macrophage colony-stimulating factor in stratified human keratinocytes2015
- Author(s)
  Takashi Sakai, Yutaka Hatano, Wei Zhang, Sakuhei Fujiwara, Ryo Nishiyori.
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 80 Issue: 2 Pages: 158-160
- DOI
  10.1016/j.jdermsci.2015.09.002
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25860958
[Journal Article] Atopic dermatitis-like dermatitis emerges unevenly on different sites in flaky tail mice.2015
- Author(s)
  Takashi Sakai, Yutaka Hatano, Haruna Matsuda-Hirose, Ryo Nishiyori, Sakuhei Fujiwara.
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 78 Issue: 2 Pages: 151-153
- DOI
  10.1016/j.jdermsci.2015.01.008
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25860958
[Journal Article] Defective maintenance of pH of stratum corneum is correlated with preferential emergence and exacerbation of atopic-dermatitis-like dermatitis in flaky-tail mice.2014
- Author(s)
  Takashi Sakai, Yutaka Hatano, Wei Zhang, Sakuhei Fujiwara.
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 印刷中 Issue: 3 Pages: 222-228
- DOI
  10.1016/j.jdermsci.2014.01.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860958
[Presentation] Serum RANKL/OPG ratio correlates with severity and suggests fracture's risk in older women with atopic dermatitis2022
- Author(s)
  Takashi Sakai, Nadine Herrmann, Laura Maintz, Tim Joachim Nümm, Thomas Welchowski, Thomas Bieber
- Organizer
  The 47th Annual Meeting of the Japanese Society of Investigative Dermatology (47th JSID)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08435
[Presentation] Site-specific microarray evaluation of spontaneous dermatitis in flaky tail mice2018
- Author(s)
  Takashi Sakai, Chinatsu Aoki, Yasuko Mori, Yutaka Hatano.
- Organizer
  International Investigative Dermatology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16347
[Presentation] Combined benefits of a protease-activated receptor 2 inhibitor and stratum corneum acidification for murine atopic dermatitis2015
- Author(s)
  Takashi Sakai, Yutaka Hatano, Haruna Matsuda-Hirose, Wei Zhang, Daisuke Takahashi, Se Kyoo Jeong, Peter M. Elias, Sakuhei Fujiwara.
- Organizer
  45th Annual ESDR Meeting
- Place of Presentation
  Rotterdam, The Netherlands
- Year and Date
  2015-09-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860958
[Presentation] Knockdown of either filaggrin or loricrin increases the productions of IL-1α, IL-8, IL-18 and GM-CSF in stratified human keratinocytes2015
- Author(s)
  Takashi Sakai, Ryo Nishiyori, Yutaka Hatano, Wei Zhang, Sakuhei Fujiwara.
- Organizer
  40th Annual Meeting of JSID
- Place of Presentation
  Okayama, Japan
- Year and Date
  2015-12-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860958
[Presentation] Increased sensitivity to stratum corneum neutralization favors the development of dermatitis in flaky-tail mice.2013
- Author(s)
  Takashi Sakai, Yutaka Hatano, Sakuhei Fujiwara.
- Organizer
  International Investigative Dermatology 2013
- Place of Presentation
  Edinburgh, Scotland.
- Data Source
  KAKENHI-PROJECT-25860958
[Presentation] Spontaneous atopic-dermatitis-like dermatitis emerges on face and neck but not whole body in flaky-tail mice.
- Author(s)
  Takashi Sakai, Yutaka Hatano, Haruna Hirose, Wei Zhang, Sakuhei Fujiwara.
- Organizer
  3rd Eastern Asia Dermatology Congress
- Place of Presentation
  Jeju, Korea.
- Year and Date
  2014-09-24 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-25860958

1. HATANO YUTAKA

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
2. FUJIWARA SAKUHEI

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. HIROSE HARUNA

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. ZHANG WEI

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. Jeong Se Kyoo

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. Elias Peter M.

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Sakai Takashi 酒井 貴史

Research Projects

Research Products

Co-Researchers

アトピー性皮膚炎患者に生じる炎症と骨異常の予防戦略開発：RANKLを標的としてPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Develop new therapeutic strategies for atopic dermatitis, focusing on stratum corneum pHPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Defective maintenance of pH of stratum corneum can induce atopic dermatitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Fracture risks and their mechanisms in atopic dermatitis, focusing on receptor activator of nuclear factor kappa-B ligand2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] アトピー性皮膚炎患者における骨折リスクと血清RANKL値の変動2023

Author(s)

Journal Title

Data Source

[Journal Article] Site-specific microarray evaluation of spontaneous dermatitis in flaky tail mice2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Wy14643, an agonist for PPARα, down-regulates expression of TARC and RANTES in cultured human keratinocytes2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Betamethasone Butyrate Propionate Inhibits the Induction of Thymic Stromal Lymphopoietin in Cultured Normal Human Keratinocytes.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Combined Benefits of a PAR2 Inhibitor and Stratum Corneum Acidification for Murine Atopic Dermatitis.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Knockdown of either filaggrin or loricrin increases the productions of interleukin (IL)-1α, IL-8, IL-18 and granulocyte macrophage colony-stimulating factor in stratified human keratinocytes2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Atopic dermatitis-like dermatitis emerges unevenly on different sites in flaky tail mice.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Defective maintenance of pH of stratum corneum is correlated with preferential emergence and exacerbation of atopic-dermatitis-like dermatitis in flaky-tail mice.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] Serum RANKL/OPG ratio correlates with severity and suggests fracture's risk in older women with atopic dermatitis2022

Author(s)

Organizer

Data Source

[Presentation] Site-specific microarray evaluation of spontaneous dermatitis in flaky tail mice2018

Author(s)

Organizer

Data Source

[Presentation] Combined benefits of a protease-activated receptor 2 inhibitor and stratum corneum acidification for murine atopic dermatitis2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Sakai Takashi 酒井貴史