yuge koutarou 弓削康太郎

… Alternative Names

Yuge Kotarou 弓削康太郎

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Researcher Number	20624472
Other IDs
Affiliation (Current)	2025: 久留米大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 久留米大学, 医学部, 講師 2017 – 2023: 久留米大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics
Keywords	Principal Investigator 睡眠障害 / 治療メカニズム / グレリン / レット症候群 / 睡眠評価法 / レット症候群モデルマウス / 治療 / 遺伝子発現 / モデルマウス / マイクロダイアリシス … More / モノアミン系神経回路 / 睡眠 / 自律神経 / 神経伝達物質 … More Except Principal Investigator レット症候群 / 不整脈 / G欠損狂犬病ウイルストレーシング法 / 三次元画像再構築 / 分化転換 / 自律神経機能障害 / 心交感神経 / 心臓分化 / モデル動物 / iPS細胞 / ES細胞 / SHANK3遺伝子 / 自律神経 / 自閉症スペクトラム / トランスレーショナルリサーチ / 振戦 / ジストニア / グレリン / MECP2 / 肺炎 / HDAC8遺伝子 / STXBP1遺伝子 / MECP2遺伝子 / 自閉症スペクトラム障害 / 発達障害 / Rett症候群 Less

Research to elucidate treatment mechanisms -Can ghrelin improve sleep disturbances in Rett syndrome?Principal Investigator
- Principal Investigator
  
  弓削康太郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kurume University
Does neurotransmitter switch of autonomic nerve lead to disturb heart-brain interaction of Rett syndrome?
- Principal Investigator
  
  原宗嗣
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kurume University
Mechanisms of treatment of Rett syndrome with ghrelin administrationPrincipal Investigator
- Principal Investigator
  
  Yuge Kotaro
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kurume University
Basic and clinical research for clarify the pathophysiology and development of new terapeutic trial for Rett syndrome
- Principal Investigator
  
  Matsuishi Toyojiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Kurume University

All 2024 2023 2022 2021 2020 2019 2017 2016 2015

All Journal Article Presentation Book Patent

[Book] 日常生活から学ぶ発達障害と睡眠2024
- Author(s)
  山下裕史郎、原宗嗣、弓削康太郎、石井隆大
- Total Pages
  272
- Publisher
  診断と治療社
- ISBN
  9784787826176
- Data Source
  KAKENHI-PROJECT-21K07858
[Journal Article] Spinal Muscular Atrophy Type I With False Negative in Newborn Screening: A Case Report2023
- Author(s)
  Hashimoto Kazuhiko、Yokokawa Mari、Yamashita Daisuke、Yuge Kotaro、Otsubo Yoshikazu
- Journal Title
  
  Cureus
  
  Volume: 15
- DOI
  10.7759/cureus.42382
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15952
[Journal Article] Gene therapy for spinal muscular atrophy is considerably effective when administered as early as possible after birth.2023
- Author(s)
  Sawada T, Kido J, Yae Y, Yuge K, Nomura K, Okada K, Fujiyama N, Ozasa S, Nakamura K.
- Journal Title
  
  Mol Genet Metab Rep.
  
  Volume: 35 Pages: 100973-100973
- DOI
  10.1016/j.ymgmr.2023.100973
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08207, KAKENHI-PROJECT-22K15952, KAKENHI-PROJECT-23K07294
[Journal Article] Associations of severity with biochemical parameters in glucose transporter 1 deficiency syndrome.2023
- Author(s)
  Nabatame S, Tanigawa J, Tominaga K, Kagitani-Shimono K, Yanagihara K, Imai K, Ando T, Tsuyusaki Y, Araya N, Matsufuji M, Natsume J, Yuge K, Bratkovic D, Arai H, Okinaga T, Matsushige T, Azuma Y, Ishihara N, Miyatake S, Kato M, Matsumoto N, Okamoto N, Takahashi S, Hattori S, Ozono K
- Journal Title
  
  J Neurol Sci
  
  Volume: 447 Pages: 120597-120597
- DOI
  10.1016/j.jns.2023.120597
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07908, KAKENHI-PROJECT-22K15952, KAKENHI-PROJECT-19K08322, KAKENHI-PROJECT-23K27520
[Journal Article] Perampanel markedly improved clinical seizures in a patient with a Rett-like phenotype and 960-kb deletion on chromosome 9q34.11 including the STXBP12022
- Author(s)
  4.Yoshida S., Amamoto M., Takahashi T., Tomita I., Yuge K., Hara M., Iwama K., Matsumoto N., Matsuishi T.
- Journal Title
  
  Clin Case Rep
  
  Volume: in press Issue: 5 Pages: 1-7
- DOI
  10.1002/ccr3.5811
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08198, KAKENHI-PROJECT-18K07893, KAKENHI-PROJECT-21K07858, KAKENHI-PROJECT-22K15952
[Journal Article] The Japanese version of the children’s sleep habits questionnaire (CSHQ-J): A validation study and influencing factors2022
- Author(s)
  Ishii Ryuta、Obara Hitoshi、Nagamitsu Shinichiro、Matsuoka Michiko、Suda Masao、Yuge Koutaro、Inoue Takeshi、Sakuta Ryoichi、Oka Yasunori、Kakuma Tatsuyuki、Matsuishi Toyojiro、Yamashita Yushiro
- Journal Title
  
  Brain and Development
  
  Volume: 44 Issue: 9 Pages: 595-604
- DOI
  10.1016/j.braindev.2022.06.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15952
[Journal Article] Meaningful word acquisition is associated with walking ability over 10 years in Rett syndrome2020
- Author(s)
  Saikusa T, Kawaguchi M, Tanioka T, Nabatame S, Takahashi S, Yuge K, Nagamitsu S, Takahashi T, Yamashita Y, Kobayashi Y, Hirayama C, Kakuma T, Matsuishi T, Itoh M.
- Journal Title
  
  Brain Dev
  
  Volume: 42(10) Issue: 10 Pages: 705-712
- DOI
  10.1016/j.braindev.2020.06.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08198, KAKENHI-PROJECT-18K15692
[Journal Article] Genetic landscape of Rett syndrome-like phenotypes revealed by whole exome sequencing2019
- Author(s)
  Iwama Kazuhiro、Mizuguchi Takeshi、Miyatake Satoko、Matsumoto Naomichi、et al
- Journal Title
  
  Journal of Medical Genetics
  
  Volume: - Issue: 6 Pages: 396-407
- DOI
  10.1136/jmedgenet-2018-105775
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10080, KAKENHI-PROJECT-16H05361, KAKENHI-PROJECT-17K15630, KAKENHI-PROJECT-18K07893, KAKENHI-PROJECT-18K19305, KAKENHI-PROJECT-18K15692, KAKENHI-PROJECT-17H01539, KAKENHI-PROJECT-16H06254
[Journal Article] Ghrelin improves dystonia and tremor in patients with Rett syndrome: A pilot study2017
- Author(s)
  Yuge K, Hara M, Okabe R, Nakamura Y, Okamura H, Nagamitsu S, Yamashita Y, Orimoto K, Kojima M, Matsuishi T
- Journal Title
  
  J Neurol Sci
  
  Volume: 377 Pages: 219-223
- DOI
  10.1016/j.jns.2017.04.022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26650025, KAKENHI-PROJECT-16K01806, KAKENHI-PROJECT-16K07281, KAKENHI-PROJECT-16K17351, KAKENHI-PROJECT-15H03459, KAKENHI-PROJECT-15K09608
[Journal Article] ADHD　児のための家庭生活評価尺度の信頼性および妥当性の検証2015
- Author(s)
  向笠　章子、山下　裕史朗、多田　泰裕、穴井　千鶴、江上　千代美、家村　明子、弓削　康太郎、松石　豊次郎
- Journal Title
  
  久留米医学会雑誌
  
  Volume: 78 Pages: 162-168
- NAID
  40020555744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09608
[Journal Article] Developmental trajectories for attention and working memory in healthy Japanese school－aged children2015
- Author(s)
  Egami C,Yamashita Y,Tada Y,Anai C,Mukasa A,Yuge K,Nagamitsu S,Matsuishi T
- Journal Title
  
  Brain Dev
  
  Volume: 37 Pages: 840-848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09608
[Patent] 外国特許出願申請2017
- Inventor(s)
  松石豊次郎、児島将康、弓削康太郎、原宗嗣、山下裕史朗
- Industrial Property Rights Holder
  松石豊次郎、児島将康、弓削康太郎、原宗嗣、山下裕史朗
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-202751
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-15K09608
[Patent] グレリンを有効成分として含有するレット症候群（ＲＴＴ）の予防・治療2016
- Inventor(s)
  松石豊次郎、弓削康太郎、児島将康、原宗嗣、山下裕史朗
- Industrial Property Rights Holder
  松石豊次郎、弓削康太郎、児島将康、原宗嗣、山下裕史朗
- Industrial Property Rights Type
  特許
- Filing Date
  2016-04-14
- Overseas
- Data Source
  KAKENHI-PROJECT-15K09608
[Presentation] West症候群における10年間の質量分析による尿中、血中メタボローム解析2023
- Author(s)
  小池敬義，山下大輔，吉塚悌子，石井隆大，弓削康太郎，原宗嗣，田代恭子，渡邊順子，山下裕史朗
- Organizer
  第65回日本小児神経学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07858
[Presentation] 当院における結節性硬化症の画像タイプ別の検証2023
- Author(s)
  石井隆大，山下大輔，弓削康太郎，小池敬義，原宗嗣，山下裕史朗
- Organizer
  第65回日本小児神経学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07858
[Presentation] 重度側弯があるにもかかわらず治療薬をrisdiplamからnusinersenへ戻した脊髄性筋萎縮症２型の成人例2023
- Author(s)
  弓削康太郎，山下大輔，八戸由佳子，石井隆大，小池敬義，原宗嗣，山下裕史朗
- Organizer
  第65回日本小児神経学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07858
[Presentation] 右内斜視を契機に脳動脈瘤の診断に至った結節性硬化症の4歳男児2023
- Author(s)
  阪田健佑，山下大輔，石井隆大，弓削康太郎，小池敬義，原宗嗣，音琴哲也，森岡基浩, 山下裕史朗
- Organizer
  第65回日本小児神経学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07858
[Presentation] レット症候群モデルマウスにおける睡眠・覚醒病態とオレキシンシグナル伝達の異常2022
- Author(s)
  弓削康太郎、高橋知之、河原幸江、坂井勇介、佐藤貴弘、児島将康、西昭徳、松石豊次郎、山下裕史朗
- Organizer
  第49回日本脳科学会
- Data Source
  KAKENHI-PROJECT-22K15952
[Presentation] Study of Sleep Disturbances In Rett　Syndrome By Mecp2-Deficient Mice2022
- Author(s)
  Kotaro Yuge, Munetsugu Hara, Tomoyuki Takahashi, Toyojiro Matsuishi, Yushiro Yamashita
- Organizer
  17th International Child Neurology Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15952
[Presentation] グレリンを用いたレット症候群の新規治療法開発、世界の治療開発のレビューを含めて2021
- Author(s)
  弓削康太郎
- Organizer
  第63回小児神経学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15692
[Presentation] 達遅延、小脳症状を認めた10歳男児2021
- Author(s)
  1.後藤康平，八戸由佳子，石井隆大，磯岡藍子，七種朋子，弓削康太郎，岡部留美子，原　宗嗣，大矢崇志，家村明子，永光信一郎，山下裕史朗
- Organizer
  第90回日本小児神経学会九州地方会
- Data Source
  KAKENHI-PROJECT-21K07858
[Presentation] MeCP2欠損マウスによるレット症候群の睡眠障害に関する研究2021
- Author(s)
  弓削康太郎, 高橋知之, 松石豊次郎, 山下裕史朗
- Organizer
  第63回小児神経学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15692
[Presentation] Questionnaire survey on fractures in patients with Rett syndrome2019
- Author(s)
  Aiko Isooka, Kotaro Yuge, Yukako Yae, Tomoyuki Takahashi, Toyojiro Matsuishi, Yushiro Yamashita
- Organizer
  15th Asian and Oceanian Congress of Child Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15692
[Presentation] A novel USP8 mutation cuses Rett syndrome-like phenotypes in a Japanese boy2019
- Author(s)
  Kotaro Yuge, Yukako Yae, Aiko Isooka, Ryuta Ishii, Shinichiro Nagamitsu, Kazuhiro Iwama, Naomichi Matsumoto, Toyojiro Matsuishi, Yushiro Yamashita
- Organizer
  15th Asian and Oceanian Congress of Child Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15692
[Presentation] 言語能力保持型レット症候群に対するアリプラゾールの言語情動機能改善効果―言語にとって情動とは何かー2017
- Author(s)
  織本健司、松石豊次郎、弓削康太郎
- Organizer
  第41回日本高次脳機能障害学会
- Data Source
  KAKENHI-PROJECT-15K09608
[Presentation] Development of therapeutic strategies for Rett syndrome2017
- Author(s)
  織本健司、松石豊次郎、弓削康太郎
- Organizer
  ConBio 2017 生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K09608
[Presentation] 言語能力保持型Rett症候群のGenotype-phenotype relationshipと治療反応性の分子制御機構2017
- Author(s)
  Orimoto K, Matsuishi T, Yuge K
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09608
[Presentation] レット症候群のグレリン治療について2016
- Author(s)
  松石豊次郎、弓削康太郎、児島将康
- Organizer
  小児神経学クリニック　瀬川塾講演
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-15K09608
[Presentation] Histone deacetylation 8（HDAC8）遺伝子変異により非典型的Rett 症候群をきたした女児の1 例2016
- Author(s)
  七種朋子、下村　豪、弓削康太郎、原　宗嗣、永光信一郎、山下裕史朗、松石豊次郎、松本直道
- Organizer
  第58回日本小児神経学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-15K09608
[Presentation] Development of the therapeutic strategies for Rett syndrome2016
- Author(s)
  Orimoto K, Matsuishi T, Yuge K
- Organizer
  第39回日本分子生物学会総会
- Place of Presentation
  横浜
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09608
[Presentation] グレリンはレット症候群の症状を改善するか？―レット症候群に対する新規治療開発の検討―2015
- Author(s)
  弓削康太郎、七種朋子、平田留美子、中村祐樹、岡村尚昌、原宗嗣、大矢崇志、永光　信一郎、山下　裕史朗、児島　将康、伊藤　雅之、松石　豊次郎
- Organizer
  第５７回日本小児神経学会学術集会
- Place of Presentation
  大阪市
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-15K09608
[Presentation] 多臓器に症状を呈し、発達遅延、てんかんのある４カ月男児2015
- Author(s)
  島さほ、寺澤藍子、下村豪、弓削康太郎、永光信一郎、山下裕史朗、松石豊次郎
- Organizer
  第７９回日本小児神経学会九州地方会
- Place of Presentation
  北九州市
- Year and Date
  2015-08-02
- Data Source
  KAKENHI-PROJECT-15K09608

1. Matsuishi Toyojiro (60157237)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. 高橋知之 (20332687)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 山下裕史朗 (90211630)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
4. 御船弘治 (70174117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 原宗嗣 (30389283)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. 高橋和之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 城戸淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 児島将康

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 宮武聡子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 高橋悟

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

yuge koutarou 弓削 康太郎

Yuge Kotarou 弓削 康太郎

Research Projects

Research Products

Co-Researchers

Research to elucidate treatment mechanisms -Can ghrelin improve sleep disturbances in Rett syndrome?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Does neurotransmitter switch of autonomic nerve lead to disturb heart-brain interaction of Rett syndrome?

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of treatment of Rett syndrome with ghrelin administrationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic and clinical research for clarify the pathophysiology and development of new terapeutic trial for Rett syndrome

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 日常生活から学ぶ発達障害と睡眠2024

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Spinal Muscular Atrophy Type I With False Negative in Newborn Screening: A Case Report2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gene therapy for spinal muscular atrophy is considerably effective when administered as early as possible after birth.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Associations of severity with biochemical parameters in glucose transporter 1 deficiency syndrome.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Perampanel markedly improved clinical seizures in a patient with a Rett-like phenotype and 960-kb deletion on chromosome 9q34.11 including the STXBP12022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Japanese version of the children’s sleep habits questionnaire (CSHQ-J): A validation study and influencing factors2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Meaningful word acquisition is associated with walking ability over 10 years in Rett syndrome2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic landscape of Rett syndrome-like phenotypes revealed by whole exome sequencing2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ghrelin improves dystonia and tremor in patients with Rett syndrome: A pilot study2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ADHD 児のための家庭生活評価尺度の信頼性および妥当性の検証2015

Author(s)

Journal Title

NAID

Data Source

yuge koutarou 弓削康太郎

Yuge Kotarou 弓削康太郎

[Journal Article] ADHD　児のための家庭生活評価尺度の信頼性および妥当性の検証2015

[Presentation] Study of Sleep Disturbances In Rett　Syndrome By Mecp2-Deficient Mice2022