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Kiyohara Hiroki  清原 裕貴

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Hiroki Kiyohara  清原 裕貴

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Researcher Number 20626379
Other IDs
Affiliation (Current) 2025: 慶應義塾大学, 医学部(信濃町), 講師(非常勤)
Affiliation (based on the past Project Information) *help 2022 – 2023: 慶應義塾大学, 医学部(信濃町), 助教
2020 – 2021: 北里大学, 北里研究所病院, 医師
2019: 北里大学, 北里研究所病院, 医員
Review Section/Research Field
Principal Investigator
Basic Section 53010:Gastroenterology-related
Keywords
Principal Investigator
炎症性腸疾患 / 腸内細菌叢 / 体軸性脊椎関節炎 / 末梢性脊椎関節炎 / 腸管外合併症 / DNA / 6-dTGTP / チオプリン製剤 / アポトーシス / 白血球 / NUDT15遺伝子 / NUDT15 / チオプリン
  • Research Projects

    (2 results)
  • Research Products

    (2 results)
  •  炎症性腸疾患の腸管外合併症における腸内細菌叢と疾患予後の検討Principal Investigator

    • Principal Investigator
      清原 裕貴
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Keio University
  •  Thiopurine metabolism associated with NUDT15 gene and clincal application.Principal Investigator

    • Principal Investigator
      Hiroki Kiyohara
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Kitasato University

All 2021 2020

All Journal Article Presentation

  • [Journal Article] Increased DNA-incorporated thiopurine metabolite as a possible mechanism for leukocytopenia through cell apoptosis in inflammatory bowel disease patients with NUDT15 mutation2021

    • Author(s)
      Toyonaga Takahiko、Kobayashi Taku、Kuronuma Satoshi、Ueno Aito、Kiyohara Hiroki、Okabayashi Shinji、Takeuchi Osamu、Redfern Christopher P. F.、Terai Hideki、Ozaki Ryo、Sagami Shintaro、Nakano Masaru、Coulthard Sally A.、Tanaka Yoichi、Hibi Toshifumi
    • Journal Title

      Journal of Gastroenterology

      Volume: 56 Issue: 11 Pages: 999-1007

    • DOI

      10.1007/s00535-021-01820-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K17443
  • [Presentation] NUDT15 variance increases DNA-incorporated thiopurine metabolites and lymphocyte apoptosis in patients with inflammatory bowel disease.2020

    • Author(s)
      Hiroki Kiyohara, Taku Kobayashi, Takahiko Toyonaga, Satoshi Kuronuma, Aito Ueno, Shinji Okabayashi, Osamu Takeuchi, Sally A. Coulthard, Christopher P. F. Redfern, Hideki Terai, Yoichi Tanaka, Ryo Ozaki, Masaru Nakano, Toshifumi Hibi
    • Organizer
      15th Congress of ECCO
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K17443

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