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Watanabe Takuya  渡邉 琢也

ORCIDConnect your ORCID iD *help
Researcher Number 20627509
Other IDs
Affiliation (Current) 2025: 国立研究開発法人国立循環器病研究センター, 病院, 医長
Affiliation (based on the past Project Information) *help 2022 – 2024: 国立研究開発法人国立循環器病研究センター, 病院, 医長
2018 – 2022: 国立研究開発法人国立循環器病研究センター, 病院, 医師
2017: 国立研究開発法人国立循環器病研究センター, 移植医療部, 医師
2016: 国立研究開発法人国立循環器病研究センター, 病院, 研究員
2015: 国立研究開発法人国立循環器病研究センター, その他部局等, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 53020:Cardiology-related / Basic Section 55030:Cardiovascular surgery-related / General surgery
Except Principal Investigator
Basic Section 53020:Cardiology-related / Basic Section 55030:Cardiovascular surgery-related
Keywords
Principal Investigator
植込型補助人工心臓 / 重症心不全 / 移植心冠動脈病変 / 病態解明 / 予後予測法 / 遺伝子関連情報 / プロテオーム / トランスクリプトーム / 原発性心筋症 / 心筋病理 … More / 移植心冠動脈硬化症 / 微小血管 / 移植免疫 / 移植後冠動脈病変 / 心臓移植後 / 機械的循環補助装置 / 心臓移植 / 好中球のRhoキナーゼ活性 / 好中球Rhoキナーゼ活性 / 冠動脈硬化症 … More
Except Principal Investigator
拒絶反応 / 心臓移植 / 低侵襲評価 / 遺伝子関連情報 / 低侵襲検査 / 遺伝子発現情報 / 移植心冠動脈病変 / HLA抗体 / non-HLA抗体 / 心筋内炎症 / 介在板 Less
  • Research Projects

    (6 results)
  • Research Products

    (39 results)
  • Co-Researchers

    (12 People)
  •  本邦の心臓移植患者におけるnon-HLA抗体の解析と拒絶反応、移植心冠動脈病変との関連

    • Principal Investigator
      望月 宏樹
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  遺伝子発現情報の解析を用いた、心臓移植後拒絶反応の低侵襲評価法の開発

    • Principal Investigator
      塚本 泰正
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  遺伝子関連情報を用いた重症心不全の予後予測法の確立と病態解明を目指す研究Principal Investigator

    • Principal Investigator
      渡邉 琢也
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  A key intercalated disc molecule determines the prognosis of dilated cardiomyopathy

    • Principal Investigator
      Shintani Yasunori
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Study of the development of low invasive predictors for the progression of coronary artery diseases in patients with heart transplantationPrincipal Investigator

    • Principal Investigator
      Watanabe Takuya
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Does Rho kinase activity predict a progression of coronary artery disease?Principal Investigator

    • Principal Investigator
      Watanabe Takuya
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General surgery
    • Research Institution
      National Cardiovascular Center Research Institute

All 2024 2023 2022 2021 2020 2019 2018 2016 2015

All Journal Article Presentation Book

  • [Book] 診断と治療112巻7号:Destination Therapy時代の重症心不全医療2024

    • Author(s)
      渡邉琢也
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-23K07519
  • [Book] Induction Therapy in the Current Immunosuppressive Therapy.2022

    • Author(s)
      Takuya Watanabe, Yasumasa Tsukamoto, Hiroki Mochizuki, Masaya Shimojima, Tasuku Hada, Satsuki Fukushima, Tomoyuki Fujita and Osamu Seguchi.
    • Total Pages
      15
    • Publisher
      Intechopen.
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Book] Novel Diagnosis and Therapeutic Approach to Antibody-Mediated Rejection in Heart transplantation.2020

    • Author(s)
      Takuya Watanabe
    • Total Pages
      92
    • Publisher
      IntechOpen
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Journal Article] Efficacy of catheter cleaning methods using intravenous indwelling catheter, 10% silver nitrate solution and a monofilament nylon thread for deeply progressed superficial driveline infections: case series2023

    • Author(s)
      Kunioka Shingo、Watanabe Takuya、Fukushima Norihide、et al
    • Journal Title

      Journal of Surgical Case Reports

      Volume: 2023 Issue: 8 Pages: 1-4

    • DOI

      10.1093/jscr/rjad443

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K07519
  • [Journal Article] Successful recovery from refractory hypoxia due to right-to-left shunting associated with iatrogenic atrial septal defect after catheter ablation in a patient with a left-ventricular assist device: a case report2022

    • Author(s)
      Shotaro Komeyama, Takuya Watanabe, Kenichiro Yamagata, Norihide Fukushima
    • Journal Title

      Eur Heart J Case Rep.

      Volume: 22 Issue: 7

    • DOI

      10.1093/ehjcr/ytac277

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Journal Article] Successful bridge to recovery in a patient with fulminant giant cell myocarditis that developed from multiple autoimmune disorders including myasthenia gravis: a case report.2022

    • Author(s)
      Nobuichiro Yagi , Takuya Watanabe , Yoshihiko Ikeda , Norihide Fukushima
    • Journal Title

      European heart journal. Case reports

      Volume: 6 Issue: 2

    • DOI

      10.1093/ehjcr/ytac046

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Journal Article] Induction therapy in the current immunosuppressive Therapy.2022

    • Author(s)
      Takuya Watanabe
    • Journal Title

      Intech open.

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Journal Article] Pulmonary Vascular Reverse Remodeling After Left Ventricular Assist Device Implantation in Patients With Pulmonary Hypertension.2022

    • Author(s)
      Anegawa E, Seguchi O, Mochizuki H, Kuroda K, Doi Nakajima S, Watanabe T, Yanase M, Tadokoro N, Fukushima S, Fujita T, Fukushima N.
    • Journal Title

      ASAIO J

      Volume: 69 Issue: 2 Pages: 151-158

    • DOI

      10.1097/mat.0000000000001739

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08413, KAKENHI-PROJECT-19K09256
  • [Journal Article] Risk Assessment of Neutropenia during Low-Dose Valganciclovir Prophylaxis for Heart Transplant Recipients2022

    • Author(s)
      Mai Otokubo , Kyoichi Wada , Megumi Ikura , Kotoka Hayase , Takaya Uno , Kazuki Nakagita , Naoki Hayakawa , Takuya Watanabe , Osamu Seguchi , Norihide Fukushima , Tsutomu Nakamura
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 45 Issue: 4 Pages: 452-459

    • DOI

      10.1248/bpb.b21-00860

    • ISSN
      0918-6158, 1347-5215
    • Year and Date
      2022-04-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09256, KAKENHI-PROJECT-20K07143
  • [Journal Article] Impact of the HeartMate 3 continuous-flow left ventricular assist device in patients with small body size2022

    • Author(s)
      Tonai Kohei、Fukushima Satsuki、Tadokoro Naoki、Kainuma Satoshi、Kawamoto Naonori、Kakuta Takashi、Koga-Ikuta Ayumi、Watanabe Takuya、Seguchi Osamu、Tsukamoto Yasumasa、Fukushima Norihide、Fujita Tomoyuki
    • Journal Title

      Interactive CardioVascular and Thoracic Surgery

      Volume: 34 Issue: 5 Pages: 902-908

    • DOI

      10.1093/icvts/ivac012

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H03017, KAKENHI-PROJECT-19K09256
  • [Journal Article] Impact of sleep-disordered breathing on ventricular tachyarrhythmias after left ventricular assist device implantation.2022

    • Author(s)
      Kumai Y, Seguchi O, Mochizuki H, Kimura Y, Iwasaki K, Kuroda K, Nakajima S, Matsumoto Y, Watanabe T, Yanase M, Sata M, Fukushima S, Fujita T, Chikamori T, Kobayashi J, Fukushima N.
    • Journal Title

      J Artif Organs

      Volume: 25 Issue: 3 Pages: 223-230

    • DOI

      10.1007/s10047-021-01307-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08413, KAKENHI-PROJECT-21H03017, KAKENHI-PROJECT-19K09256
  • [Journal Article] Reversible left ventricular dysfunction due to severe stenosis of the elephant trunk graft: A case report2021

    • Author(s)
      Eiji Anegawa, Takuya Watanabe
    • Journal Title

      J Cardiol Cases

      Volume: 24 Issue: 4 Pages: 173-176

    • DOI

      10.1016/j.jccase.2021.03.010

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Journal Article] The Predictive Value of Changes in Body Mass Index for the Incidence of Device-Specific Infections in Patients With Implantable Left Ventricular Assist Devices2021

    • Author(s)
      Yasumori Sujino
    • Journal Title

      Circ J

      Volume: 85 Issue: 9 Pages: 1460-1468

    • DOI

      10.1253/circj.CJ-20-1197

    • NAID

      130008077941

    • ISSN
      1346-9843, 1347-4820
    • Year and Date
      2021-08-25
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Journal Article] Influence of Induction Therapy Using Basiliximab With Delayed Tacrolimus Administration in Heart Transplant Recipients ― Comparison With Standard Tacrolimus-Based Triple Immunosuppression ―2020

    • Author(s)
      Takuya Watanabe
    • Journal Title

      Circ J

      Volume: 84 Issue: 12 Pages: 2212-2223

    • DOI

      10.1253/circj.CJ-20-0164

    • NAID

      130007942481

    • ISSN
      1346-9843, 1347-4820
    • Year and Date
      2020-11-25
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Journal Article] Suppressive effects of conversion from mycophenolate mofetil to everolimus for the development of cardiac allograft vasculopathy in maintenance of heart transplant recipients2016

    • Author(s)
      Takuya Watanabe
    • Journal Title

      International Journal of Cardiology

      Volume: 203 Pages: 307-314

    • DOI

      10.1016/j.ijcard.2015.10.082

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K21697
  • [Journal Article] Donor-transmitted atherosclerosis associated with worsening cardiac allograft vasculopathy after heart transplantation: Serial volumetric intravascular ultrasound analysis2016

    • Author(s)
      Takuya Watanabe
    • Journal Title

      Transplantation

      Volume: In press Issue: 6 Pages: 1310-1319

    • DOI

      10.1097/tp.0000000000001322

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K21697
  • [Presentation] Initial Hospitalization Costs of Implantable Left Ventricular Assist Devices : Analysis using the JROAD-DPC database2024

    • Author(s)
      Takuya Watanabe, Yasumasa Tsukamoto, et al.
    • Organizer
      日本循環器学会学術集会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K07519
  • [Presentation] Current therapeutic strategies using newly developed mechanical circulatory support devices for patients with acute cardiogenic shock and advanced heart failure2023

    • Author(s)
      Takuya Watanabe,
    • Organizer
      The 87th Annual Scientific Meeting of the Japanese Circulation Society JCS 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Presentation] Destination therapy時代の補助人工心臓を用いた最適なbridge to decision (BTD)治療戦略2022

    • Author(s)
      渡邉 琢也
    • Organizer
      第50回人工心臓と補助循環懇話会 学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Presentation] Bridge to bridge(BTB)におけるBiofloat VADの有用性2022

    • Author(s)
      渡邉 琢也
    • Organizer
      第28回日本臨床補助人工心臓研究会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Presentation] 急性循環不全に対する機械的循環補助を用いた治療戦略2022

    • Author(s)
      渡邉 琢也
    • Organizer
      第60回日本人工臓器学会大会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Presentation] 機械的循環補助デバイスを用いた急性心不全治療戦略の現状と課題2022

    • Author(s)
      渡邉 琢也
    • Organizer
      第60回日本人工臓器学会大会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Presentation] Management of Non-cardiac Comorbidities in Patients with Implantable Left Ventricular Assist Device2022

    • Author(s)
      Takuya Watanabe
    • Organizer
      Annual meeting, The Japanese Circulation Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Presentation] 心臓移植後の抗体関連拒絶反応とその治療及びドナー特異的抗HLA抗体との関連性の検討2021

    • Author(s)
      渡邉 琢也
    • Organizer
      日本移植学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Presentation] DT-LVAD治療の課題と取り組み2021

    • Author(s)
      渡邉 琢也
    • Organizer
      日本人工臓器学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Presentation] The Era of Destination Therapy is Coming to Japan ー Are We ready for It?2020

    • Author(s)
      Takuya Watanabe
    • Organizer
      JCS annual meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Presentation] Donor-transmitted atherosclerosis and the occurrence of cardiac antibody-mediated rejection influenced on the development of cadiac allograft vasculopathy2020

    • Author(s)
      Takuya Watanabe
    • Organizer
      ISHLT annual meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Presentation] Donor-transmitted atherosclerosis and the occurrence of cardiac antibody-mediated rejection influenced on the development of cardiac allograft vasculopathy.2020

    • Author(s)
      渡邉 琢也
    • Organizer
      International society of heart and lung transplantation; Annual meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Presentation] Is exercise rehabilitation indicated for advanced heart failure patients receiving an intravenous inotropic agent2020

    • Author(s)
      Takuya Watanabe
    • Organizer
      JCS annual meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Presentation] The development of cardiac allograft vasculopathy occurs in early intimal thickening and constrictive remodeling in long-term period; Long-term serial intravascular ultrasound study2020

    • Author(s)
      竹内 智/渡邉 琢也
    • Organizer
      International society of heart and lung transplantation; Annual meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Presentation] 心臓移植における抗体関連型拒絶反応を抑制するための国立循環器病研究センターの診断・治療戦略について2019

    • Author(s)
      渡邉 琢也
    • Organizer
      日本移植学会
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Presentation] 国立循環器病研究センターにおける移植心冠動脈病変の現状2019

    • Author(s)
      渡邉 琢也
    • Organizer
      日本移植学会
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Presentation] A comparison of novel developed centrifugal-flow and conventional pulsatile-flow extracorporel left ventricular assist devices in patients with cardiogenic shocks as bridge to candidacy for heart transplantation2019

    • Author(s)
      Takuya Watanabe
    • Organizer
      International society of mechanical circulatory support conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09256
  • [Presentation] The influence of induction therapy using basiliximab on clinical prognosis in high-risk transplant recipients2018

    • Author(s)
      Takuya Watanabe
    • Organizer
      Transplantation Science Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K21697
  • [Presentation] Relationship between brachial artery flow-mediated vasodilation and clinical characteristics of heart transplant recipients2016

    • Author(s)
      Takuya Watanabe
    • Organizer
      36th Annual meeting and scientific sessions
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2016-04-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K21697
  • [Presentation] Does flow-mediated dilation of brachial artery predict development of cardiac allograft vasculopathy in heart transplant recipients? Prospective observational study.2016

    • Author(s)
      Takuya Watanabe
    • Organizer
      第80回日本循環器学会学術集会
    • Place of Presentation
      宮城県 仙台市
    • Year and Date
      2016-03-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K21697
  • [Presentation] Relationship between brachial artery flow-mediated dilation and clinical characteristics of heart transplantation2016

    • Author(s)
      Takuya Watanabe
    • Organizer
      26th International congress of the transplantation society
    • Place of Presentation
      Hong kong
    • Year and Date
      2016-08-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K21697
  • [Presentation] Relationship between brachial artery flow-mediated vasodilation and clinical characteristics of heart transplant recipients2016

    • Author(s)
      Takuya Watanabe
    • Organizer
      International society for heart and lung transplantation, anual meeting
    • Place of Presentation
      Washington DC
    • Year and Date
      2016-04-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K21697
  • [Presentation] 心臓移植後患者の上腕動脈の血流依存性血管拡張反応(Flow-mediated dilation;FMD)は、移植心冠動脈病変の重症度と関連する.2015

    • Author(s)
      渡邉 琢也
    • Organizer
      日本血管生物医学会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2015-12-10
    • Data Source
      KAKENHI-PROJECT-15K21697
  • 1.  塚本 泰正 (80747072)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 2.  Shintani Yasunori (20712243)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  松本 学 (30408827)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  大郷 恵子 (30601827)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  白井 学 (70294121)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  山崎 悟 (70348796)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  高橋 佑典 (70880912)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  望月 宏樹 (90869645)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  SEGUCHI Osamu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 10.  FUJITA Tomoyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  生田 亜由美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  福嶌 五月
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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