Tayu Masanori 田湯正法

Researcher Number	20632780
Other IDs	https://orcid.org/0000-0002-9433-5842
Affiliation (Current)	2024: 明治薬科大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 明治薬科大学, 薬学部, 助教 2017 – 2020: 明治薬科大学, 薬学部, 助教 2013 – 2015: 明治薬科大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Chemical pharmacy / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
Keywords	Principal Investigator 複素環 / 有機化学 / スルホキシド / 天然物合成 / インドール / 遷移金属触媒 / ビニリデン / イナミド / 環化反応 / 硫黄 … More / C-H官能基化 / 有機硫黄化学 / 芳香族求核置換反応 / スルホニウム / ヘテロカップリング / ワンポット / ピロロインドール / 天然物 / アルカロイド / C2対称性 / 不斉合成 Less

イナミドから生じるメタルビニリデン種を駆使した含窒素複素環構築法の開発Principal Investigator
- Principal Investigator
  
  田湯正法
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Meiji Pharmaceutical University
Study for DMSO-Tf2O-triggered direct fuctionalization of aromatic ringPrincipal Investigator
- Principal Investigator
  
  Tayu Masanori
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Meiji Pharmaceutical University
Development of one-pot synthesis of 3a-subsituted pyrroloindole and exhaustive synthesis of associated biologically active natural productsPrincipal Investigator
- Principal Investigator
  
  Tayu Masanori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Meiji Pharmaceutical University

All 2023 2022 2021 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] The Interrupted Pummerer Reaction: Design of Sulfoxides and Their Utility in Organic Synthesis2021
- Author(s)
  Kazuhiro HIguchi, Masanori Tayu
- Journal Title
  
  Heterocycles
  
  Volume: 102 Issue: 5 Pages: 783-824
- DOI
  10.3987/rev-20-935
- NAID
  40022572786
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15427
[Journal Article] A metal-free biaryl coupling reaction activated by a sulfonium salt2018
- Author(s)
  Higuchi Kazuhiro、Tago Takuhiro、Kokubo Yusuke、Ito Motoki、Tayu Masanori、Sugiyama Shigeo、Kawasaki Tomomi
- Journal Title
  
  Organic Chemistry Frontiers
  
  Volume: 5 Issue: 22 Pages: 3219-3225
- DOI
  10.1039/c8qo00798e
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15427, KAKENHI-PROJECT-17K15428, KAKENHI-PROJECT-16K08181
[Journal Article] Functionalizations of Indoles by Intermolecular Interrupted Pummerer Reaction2018
- Author(s)
  Tayu Masanori、Higuchi Kazuhiro、Kawasaki Tomomi
- Journal Title
  
  Journal of Synthetic Organic Chemistry, Japan
  
  Volume: 76 Issue: 7 Pages: 678-689
- DOI
  10.5059/yukigoseikyokaishi.76.678
- NAID
  130007403450
- ISSN
  0037-9980, 1883-6526
- Year and Date
  2018-07-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15427
[Journal Article] Total Synthesis of (+)-Gliocladin C Based on One-Pot Construction of a 3a-(3-Indolyl)pyrroloindoline Skeleton by Sulfonium-Mediated Cross-Coupling of Tryptophan and Indole2017
- Author(s)
  Tayu, M.; Hui, Y.; Takeda, S.; Higuchi, K.; Saito, N.; Kawasaki, T
- Journal Title
  
  Org. Lett.
  
  Volume: 19 Issue: 24 Pages: 6582-6585
- DOI
  10.1021/acs.orglett.7b03293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08181, KAKENHI-PROJECT-17K08226, KAKENHI-PROJECT-17K15427
[Journal Article] Direct C2-Functionalization of Indoles Triggered by the Generation of Iminium Species from Indole and Sulfonium Salt2017
- Author(s)
  Masanori Tayu, Kazuya Nomura, Koki Kawachi, Kazuhiro Higuchi, Nozomi Saito, Tomomi Kawasaki
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 23 Issue: 45 Pages: 10925-10930
- DOI
  10.1002/chem.201702338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08181, KAKENHI-PROJECT-17K08226, KAKENHI-PROJECT-17K15427
[Journal Article] C2-Symmetric Chiral Sulfoxide-Mediated Intermolecular Interrupted Pummerer Reaction for Enantioselective Construction of C3a-Substituted Pyrroloindolines2016
- Author(s)
  Masanori Tayu, Takako Ishizaki, Kazuhiro Higuchi, Tomomi Kawasaki
- Journal Title
  
  Synlett
  
  Volume: 27 Issue: 06 Pages: 941-945
- DOI
  10.1055/s-0035-1560548
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25860014
[Journal Article] Asymmetric Total Synthesis of (–)-Leuconoxine via Chiral Phosphoric Acid-Catalyzed Desymmetrization of a Prochiral Diester2015
- Author(s)
  K. Higuchi, S. Suzuki, R. Ueda, N. Oshima, E. Kobayashi, M. Tayu, T. Kawasaki
- Journal Title
  
  Org. Lett.
  
  Volume: 17 Issue: 1 Pages: 154-157
- DOI
  10.1021/ol5033865
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590032, KAKENHI-PROJECT-25860014
[Journal Article] DMSO/Tf2O-Mediated Cross-Coupling of Tryptamine with Substituted Aniline to Access C3a-N1'-Linked Pyrroloindoline Alkaloids2015
- Author(s)
  M. Tayu, T. Ishizaki, K. Higuchi, T. Kawasaki
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 13 Issue: 13 Pages: 3863-3865
- DOI
  10.1039/c5ob00190k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590032, KAKENHI-PROJECT-25860014
[Journal Article] Hypervalent Iodine Mediated One-pot C-H Functionarization at 2α- or 3α-Position of Indole Derivatives2014
- Author(s)
  K. Higuchi, M. Inaba, A. Naganuma, T. Ishizaki, M. Tayu, T. Kawasaki
- Journal Title
  
  Heterocycles
  
  Volume: 89 Issue: 9 Pages: 2105-2121
- DOI
  10.3987/com-14-13065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590032, KAKENHI-PROJECT-25860014
[Presentation] イナミドから生じるルテニウムビニリデン種を基盤としたアゼピノインドール合成法2023
- Author(s)
  新島裕樹、田湯正法、黒沢匡貴、渡邉隆太、大類　彩、齋藤　望
- Organizer
  第67回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-22K06538
[Presentation] イナミドから生じるルテニウムビニリデン中間体を経たアゼピノインドール骨格構築法2022
- Author(s)
  渡邉隆太・新島裕樹・黒沢匡貴・田湯正法・大類彩・齋藤望
- Organizer
  第51回複素環化学討論会
- Data Source
  KAKENHI-PROJECT-22K06538
[Presentation] スルホニウム種によるピロロインドリンワンポット合成法を利用した(+)-gliocladin C の不斉全合成2017
- Author(s)
  回芸、田湯正法、武田詩織、樋口和宏、齋藤望、川﨑知己
- Organizer
  第47回複素環化学討論会
- Data Source
  KAKENHI-PROJECT-17K15427
[Presentation] ジアステレオ選択的ピロロインドリン骨格ワンポット構築反応の開発と(+)-gliocladin C合成研究への応用2017
- Author(s)
  回芸、田湯正法、武田詩織、樋口和宏、齋藤望、川﨑知己
- Organizer
  第73回有機合成化学協会関東支部シンポジウム
- Data Source
  KAKENHI-PROJECT-17K15427
[Presentation] C2対称キラルスルホキシドにより誘起されるエナンチオ選択的分子間Interrupted Pummerer 反応2015
- Author(s)
  田湯正法、鈴木由衣、樋口和宏、川﨑知己
- Organizer
  第45回複素環化学討論会
- Place of Presentation
  東京
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-25860014
[Presentation] Chiral Sulfoxide-Mediated First Intermolecular Interrrupted Pummerer Reaction for Enantioselective Synthesis of C3a-Substituted Pyrroloindolines2015
- Author(s)
  Tayu M, Suzuki Y, Higuchi K, Kawasaki T
- Organizer
  13th International Kyoto Conference New Aspects of Organic Chemistry
- Place of Presentation
  京都
- Year and Date
  2015-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860014
[Presentation] 高効率的3a 位置換ピロロインドリン骨格構築法の開発と天然物合成への応用
- Author(s)
  田湯正法
- Organizer
  第39回反応と合成の進歩シンポジウム
- Place of Presentation
  九州大学医学部百年講堂
- Data Source
  KAKENHI-PROJECT-25860014
[Presentation] 天然物合成を指向した3a 位置換ピロロインドリン骨格のワンポット構築反応
- Author(s)
  田湯正法
- Organizer
  第11回次世代を担う有機化学シンポジウム
- Place of Presentation
  日本薬学会長井記念ホール
- Data Source
  KAKENHI-PROJECT-25860014
[Presentation] キラルスルホキシドを用いた 3a-インドリルピロロインドリン骨格のワンポット不斉合成法の開発
- Author(s)
  田湯正法, 樋口和宏, 鈴木由衣, 川﨑知己
- Organizer
  第40回反応と合成の進歩シンポジウム
- Place of Presentation
  東北大学　川内萩ホール
- Year and Date
  2014-11-10 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-25860014
[Presentation] DMSO-TFAAによるインドール2位での芳香族求核置換反応の開発
- Author(s)
  河内晃樹, 田湯正法, 樋口和宏, 川﨑知己
- Organizer
  日本薬学会　第135年会
- Place of Presentation
  デザイン・クリエイティブセンター神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25860014

1. Hui Yi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. Saito Nozomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. Ito Motoki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 樋口和宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 川崎知己

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Tayu Masanori 田湯 正法

Research Projects

Research Products

Co-Researchers

イナミドから生じるメタルビニリデン種を駆使した含窒素複素環構築法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study for DMSO-Tf2O-triggered direct fuctionalization of aromatic ringPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of one-pot synthesis of 3a-subsituted pyrroloindole and exhaustive synthesis of associated biologically active natural productsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The Interrupted Pummerer Reaction: Design of Sulfoxides and Their Utility in Organic Synthesis2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] A metal-free biaryl coupling reaction activated by a sulfonium salt2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functionalizations of Indoles by Intermolecular Interrupted Pummerer Reaction2018

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Total Synthesis of (+)-Gliocladin C Based on One-Pot Construction of a 3a-(3-Indolyl)pyrroloindoline Skeleton by Sulfonium-Mediated Cross-Coupling of Tryptophan and Indole2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Direct C2-Functionalization of Indoles Triggered by the Generation of Iminium Species from Indole and Sulfonium Salt2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] C2-Symmetric Chiral Sulfoxide-Mediated Intermolecular Interrupted Pummerer Reaction for Enantioselective Construction of C3a-Substituted Pyrroloindolines2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Asymmetric Total Synthesis of (–)-Leuconoxine via Chiral Phosphoric Acid-Catalyzed Desymmetrization of a Prochiral Diester2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DMSO/Tf2O-Mediated Cross-Coupling of Tryptamine with Substituted Aniline to Access C3a-N1'-Linked Pyrroloindoline Alkaloids2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hypervalent Iodine Mediated One-pot C-H Functionarization at 2α- or 3α-Position of Indole Derivatives2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] イナミドから生じるルテニウムビニリデン種を基盤としたアゼピノインドール合成法2023

Author(s)

Organizer

Data Source

[Presentation] イナミドから生じるルテニウムビニリデン中間体を経たアゼピノインドール骨格構築法2022

Author(s)

Organizer

Data Source

Tayu Masanori 田湯正法