Kato Tamotsu 加藤完

Researcher Number	20632946
Other IDs	https://orcid.org/0000-0002-8407-4327
Affiliation (Current)	2025: 国立研究開発法人理化学研究所, 生命医科学研究センター, 専門技術員
Affiliation (based on the past Project Information) *help	2023 – 2024: 国立研究開発法人理化学研究所, 生命医科学研究センター, 専門技術員 2019 – 2022: 国立研究開発法人理化学研究所, 生命医科学研究センター, 研究員 2016 – 2018: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, 特別研究員 2015: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, リサーチアソシエート
Review Section/Research Field	Principal Investigator Basic Section 38050:Food sciences-related / Food science Except Principal Investigator Medium-sized Section 49:Pathology, infection/immunology, and related fields / Basic Section 57030:Conservative dentistry-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 49070:Immunology-related / Periodontology
Keywords	Principal Investigator プレバイオティクス / 腸内細菌 / フラクトオリゴ糖 / 真菌叢 / 真菌 / マルチオミクス Except Principal Investigator 腸内細菌叢 / 腸内細菌 / 潰瘍性大腸炎 / 統合オミクス解析 … More / 自己免疫疾患 / 多発性硬化症 / 全身疾患 / 口腔細菌 / 歯周炎 / 口腸連関 / 早産児・低出生体重児 / 腸管バリア / トランス脂肪酸 / 2型糖尿病 / GPR41 / プロピオン酸 / 喘息 / エンドリシン / 小児アレルギー / メタボローム / 糖尿病 / アレルギー / 宿主ー腸内細菌叢相互作用 / 回腸嚢炎 / T細胞 / 自己免疫 / 炎症性腸疾患 / 統合オミクス手法 / 大腸炎 / IgA / Th17型Ｔ細胞 / 自己抗原交叉ペプチド / CD8陽性制御性Ｔ細胞 / １型糖尿病 / STZ誘導1型糖尿病 / 実験的自己免疫性脳脊髄炎（EAE) / CD8+制御性Ｔ細胞 / ルミノコッカス属菌 / トレハロース / 寄生虫 / 1型糖尿病 / EAE（実験的自己免疫性脳脊髄炎） / 関節リウマチ / 歯周病 / 非感染性疾患 / ペリオドンタルメディスン / dysbiosis / 代謝性疾患 / 歯周病原細菌 Less

早産児・低出生体重児における重症感染症関連病原性常在細菌(Pathobiont)の検索
- Principal Investigator
  
  野瀬聡子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Hyogo Medical University
Elucidation of the mechanisms of oral-gut connection in inflammaging induced by periodontitis
- Principal Investigator
  
  山崎和久
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Institute of Physical and Chemical Research
潰瘍性大腸炎における腸内細菌叢ー免疫系の相互作用の解析
- Principal Investigator
  
  小椋英樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Hyogo Medical University
宿主ー腸内細菌叢相互作用が宿主の病理に及ぼす影響の研究
- Principal Investigator
  
  大野博司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Institute of Physical and Chemical Research
The alteration of gut microbiome during treatment of pouchitis in patients with ulcerative colitis.
- Principal Investigator
  
  Uchino Motoi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Hyogo Medical University
Mechanism of changes in microbiome and mycobiome by fructo-oligosaccharide intakePrincipal Investigator
- Principal Investigator
  
  Kato Tamotsu
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Institute of Physical and Chemical Research
The impact of gut microbiota on autoimmune diseases
- Principal Investigator
  
  Ohno Hiroshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Institute of Physical and Chemical Research
Analysis of intestinal environmental change by intake of fructooligosaccharide in the ultra-short termPrincipal Investigator
- Principal Investigator
  
  Kato Tamotsu
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Food science
- Research Institution
  Institute of Physical and Chemical Research
Integrated analysis of perio-systemic association based on the oral-gut connection
- Principal Investigator
  
  Yamazaki Kazuhisa
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Periodontology
- Research Institution
  Niigata University

All 2024 2023 2021 2020 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Gut microbiota and fecal metabolites in sustained unresponsiveness by oral immunotherapy in school-age children with cow's milk allergy2024
- Author(s)
  Shibata Ryohei、Itoh Naoka、Nakanishi Yumiko、Kato Tamotsu、Suda Wataru、Nagao Mizuho、Iwata Tsutomu、Yoshida Hideo、Hattori Masahira、Fujisawa Takao、Shimojo Naoki、Ohno Hiroshi
- Journal Title
  
  Allergol. Int.
  
  Volume: 73 Issue: 1 Pages: 126-136
- DOI
  10.1016/j.alit.2023.10.001
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H00452
[Journal Article] Fatty acid overproduction by gut commensal microbiota exacerbates obesity2023
- Author(s)
  Takeuchi Tadashi、Kameyama Keishi、Miyauchi Eiji、Nakanishi Yumiko、Kanaya Takashi、Fujii Takayoshi、Kato Tamotsu、Sasaki Takaharu、Tachibana Naoko、Negishi Hiroki、Matsui Misato、Ohno Hiroshi
- Journal Title
  
  Cell Metabolism
  
  Volume: 35 Issue: 2 Pages: 361-375.e9
- DOI
  10.1016/j.cmet.2022.12.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05907, KAKENHI-PROJECT-22H00452
[Journal Article] Bacterial cancer therapy in autochthonous colorectal cancer affects tumor growth and metabolic landscape2021
- Author(s)
  Mackie Gillian M.、Copland Alastair、Takahashi Masumi、Nakanishi Yumiko、Everard Isabel、Kato Tamotsu、Oda Hirotsugu、Kanaya Takashi、Ohno Hiroshi、Maslowski Kendle M.
- Journal Title
  
  JCI Insight
  
  Volume: 6 Issue: 23
- DOI
  10.1172/jci.insight.139900
- Data Source
  KAKENHI-PROJECT-19H01030
[Journal Article] Acetate differentially regulates IgA reactivity to commensal bacteria2021
- Author(s)
  Takeuchi Tadashi、Miyauchi Eiji、Kanaya Takashi、Kato Tamotsu、Nakanishi Yumiko、Watanabe Takashi、Kitami Toshimori、Taida Takashi、Sasaki Takaharu、Negishi Hiroki、Shimamoto Shu、Matsuyama Akinobu、Kimura Ikuo、Williams Ifor R.、Ohara Osamu、Ohno Hiroshi
- Journal Title
  
  Nature
  
  Volume: 595 Issue: 7868 Pages: 560-564
- DOI
  10.1038/s41586-021-03727-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H01030, KAKENHI-PROJECT-21H04862, KAKENHI-PROJECT-19K05907
[Journal Article] CD8+ regulatory T cells are critical in prevention of autoimmune-mediated diabetes2020
- Author(s)
  3.Shimokawa C, Kato T, Takeuchi T, Ohshima N, Furuki T, Ohtsu Y, Suzue K, Imai T, Obi S, Olia A, Izumi T, Sakurai M, Arakawa H, Ohno H, Hisaeda H
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 1922-1922
- DOI
  10.1038/s41467-020-15857-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07530, KAKENHI-PROJECT-19K16682, KAKENHI-PROJECT-19H01030
[Journal Article] Increased serum PCSK9, a potential biomarker to screen for periodontitis, and decreased total bilirubin associated with probing depth in a Japanese community survey2018
- Author(s)
  Tabeta K.、Hosojima M.、Nakajima M.、Miyauchi S.、Miyazawa H.、Takahashi N.、Matsuda Y.、Sugita N.、Komatsu Y.、Sato K.、Ishikawa T.、Akiishi K.、Yamazaki K.、Kato K.、Saito A.、Yoshie H.
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: 印刷中 Issue: 3 Pages: 446-456
- DOI
  10.1111/jre.12533
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02578, KAKENHI-PROJECT-15H05052, KAKENHI-PROJECT-17H06700, KAKENHI-PROJECT-17H06701, KAKENHI-PROJECT-17K09104, KAKENHI-PROJECT-16K11827
[Journal Article] Aggravation of collagen-induced arthritis by orally administered Porphyromonas gingivalis through modulation of the gut microbiota and gut immune system.2017
- Author(s)
  Sato K, Takahashi N, Kato T, Matsuda Y, Yokoji M, Yamada M, Nakajima T, Kondo N, Endo N, Yamamoto R, Noiri Y, Ohno H, Yamazaki K
- Journal Title
  
  Sci. Rep.
  
  Volume: 7(1) Issue: 1 Pages: 6955-6955
- DOI
  10.1038/s41598-017-07196-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11827, KAKENHI-PROJECT-15H02578, KAKENHI-PROJECT-15H05021, KAKENHI-PROJECT-16H05554, KAKENHI-PROJECT-17H06701
[Journal Article] Ligature-induced periodontitis in mice induces elevated levels of circulating IL-6 but shows only weak effects on adipose and liver tissues.2016
- Author(s)
  3.Matsuda Y, Kato T, Takahashi N, Nakajima M, Arimatsu K, Minagawa T, Sato K, Ohno H, Yamazaki K.
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: 51 Issue: 5 Pages: 639-646
- DOI
  10.1111/jre.12344
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02578, KAKENHI-PROJECT-25463216, KAKENHI-PROJECT-26861808, KAKENHI-PROJECT-16K11827
[Journal Article] Oral Administration of P. gingivalis Induces Dysbiosis of Gut Microbiota and Impaired Barrier Function Leading to Dissemination of Enterobacteria to the Liver.2015
- Author(s)
  4.Nakajima M, Arimatsu K, Kato T, Matsuda Y, Minagawa T, Takahashi N, Ohno H, Yamazaki K.
- Journal Title
  
  PLoS ONE
  
  Volume: 10 Issue: 7 Pages: 1-15
- DOI
  10.1371/journal.pone.0134234
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02578, KAKENHI-PROJECT-13J04959
[Presentation] Periodontopathic bacteria increases the severity of collagen-induced arthritis by affecting gut microbiota.2017
- Author(s)
  Yamazaki K, Sato K, Takahashi N, Kato T, Matsuda Y, Yokoji M, Yamada M, Yamazaki K, Nakajima T, Hiroshi Ohno.
- Organizer
  PgMelbourne
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02578
[Presentation] Periodontopathic bacteria increases the risk of rheumatoid arthritis by affecting gut immune system.2016
- Author(s)
  Sato K, Takahashi N, Nakajima M, Kato T, Matsuda Y, Yokoji M, Yamada M, Ohno H, Yamazaki K.
- Organizer
  International Congress of Immunology 2016
- Place of Presentation
  メルボルン（オーストラリア）
- Year and Date
  2016-08-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02578
[Presentation] 歯周炎モデルマウスにおける腸内細菌叢の変動と免疫応答への影響．2015
- Author(s)
  高橋直紀、有松　圭、中島麻由佳、松田由実、佐藤圭祐、多部田康一、中島貴子，加藤　完、大野博司、山崎和久．
- Organizer
  第19回腸内細菌学会
- Place of Presentation
  北里大学（東京都・港区）
- Year and Date
  2015-06-18
- Data Source
  KAKENHI-PROJECT-15H02578

1. Ohno Hiroshi (50233226)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
2. 中西裕美子 (10614274)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. 宮内栄治 (60634706)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. 孫安生 (30447924)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. Yamazaki Kazuhisa (00182478)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
6. 下川周子 (60708569)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 小椋英樹 (20573174)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 池内浩基 (80319863)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 石戸聡 (10273781)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. Uchino Motoi (00388810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 池田正孝 (80335356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 堀尾勇規 (10838999)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 皆川知洋 (70839000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 桑原隆一 (90839010)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 伊藤崇 (20823561)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 野瀬聡子 (90467564)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 竹島泰弘 (40281141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 銭谷昌弘 (40643531)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 大植孝治 (50314315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 松尾禎之 (50447926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 久枝一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 高橋直紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kato Tamotsu 加藤 完

Research Projects

Research Products

Co-Researchers

早産児・低出生体重児における重症感染症関連病原性常在細菌(Pathobiont)の検索

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanisms of oral-gut connection in inflammaging induced by periodontitis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

潰瘍性大腸炎における腸内細菌叢ー免疫系の相互作用の解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

宿主ー腸内細菌叢相互作用が宿主の病理に及ぼす影響の研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The alteration of gut microbiome during treatment of pouchitis in patients with ulcerative colitis.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of changes in microbiome and mycobiome by fructo-oligosaccharide intakePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The impact of gut microbiota on autoimmune diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of intestinal environmental change by intake of fructooligosaccharide in the ultra-short termPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Integrated analysis of perio-systemic association based on the oral-gut connection

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Gut microbiota and fecal metabolites in sustained unresponsiveness by oral immunotherapy in school-age children with cow&apos;s milk allergy2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Fatty acid overproduction by gut commensal microbiota exacerbates obesity2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bacterial cancer therapy in autochthonous colorectal cancer affects tumor growth and metabolic landscape2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acetate differentially regulates IgA reactivity to commensal bacteria2021

Author(s)

Journal Title

DOI

Data Source

Kato Tamotsu 加藤完

[Journal Article] Gut microbiota and fecal metabolites in sustained unresponsiveness by oral immunotherapy in school-age children with cow's milk allergy2024