TAMURA Tamura 田村孝史

Researcher Number	20633192
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2021: 筑波大学, 医学医療系, 研究員 2012 – 2015: 筑波大学, 医学医療系, 講師
Review Section/Research Field	Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related Except Principal Investigator Digestive surgery / Basic Section 55020:Digestive surgery-related / General surgery
Keywords	Principal Investigator Drug Delivery System / 肝線維化 / アデノシン / 肝星細胞 / 膵液瘻ラットモデル / ハイドロゲル / 膵液瘻 / MEND / Bax / Apoptosis … More / SiRNA / DDS / SiRNA, Bax / アポトーシス / 肝細胞 / 肝類洞内皮細胞 / α-SMA / TIMP-1 / RT-PCR / 肝線維化モデル / drug delivery system / ATP … More Except Principal Investigator 血小板 / 大腸癌 / 肝微小循環 / クッパー細胞 / 肝転移 / ヒアルロン酸 / インスリン抵抗性 / LXR / 肝細胞癌 / 非アルコール性脂肪性肝疾患 / 最大腫瘍径 / 腫瘍最大径 / SGLT-2 / Src / NASH肝発癌 / NASH / キメララット / 間葉系幹細胞 / 血管内皮前駆細胞 / 体性幹細胞 / 間葉系細胞 / 造血幹細胞 / 血管内皮前駆細、 / 肝オルガノイド / 羊膜上皮細胞 / 再生医療 / ヒト化ラット / 生体顕微鏡 / 生体蛍光顕微鏡 / 肝臓外科学 / 肝類洞 / 蛍光顕微鏡 / 微小循環 / 炎症性サイトカイン / 膠着 / 癌細胞 / PRP / 消化器吻合 / 膵液瘻 / 縫合不全 / ハイドロゲル / テーラーメイド医療 / IL-2 / 免疫抑制薬 / 薬剤感受性 / 免疫抑制 / ナノバイオ / S1P / 肝硬変 / 線維化抑制 / 肝再生 Less

Analysis of carcinogenesis mechanism and development of novel therapeutic agents using a novel mouse model of NASH hepatocarcinogenesis
- Principal Investigator
  
  Ohkohchi Nobuhiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  University of Tsukuba
Development of a novel method of prevention for pancreatic fistula using hydrogel sheetsPrincipal Investigator
- Principal Investigator
  
  Tamura Takafumi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  University of Tsukuba
A novel hydrogel sheet prevents postoperative anastomotic leakage in a rat model
- Principal Investigator
  
  hisakura katsuji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Tsukuba
Clarification of the mechanisms of cancer cell attachment and infiltration to suppress liver metastasis, and development of its prophylaxis.
- Principal Investigator
  
  kondo tadashi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Tsukuba
Rat liver disease modeling with humanized liver and immune system
- Principal Investigator
  
  Zheng Yunwen
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  University of Tsukuba
Protecting liver sinusoidal endothelial cells suppresses apoptosis in acute liver damagePrincipal Investigator
- Principal Investigator
  
  TAMURA Takafumi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Tsukuba
ナノバイオ装置を用いた新規免疫抑制薬感受性試験の開発
- Principal Investigator
  
  福永潔
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  University of Tsukuba
mechanism of liver metastasis focused on the interaction between tumor cells and Kupffer cells
- Principal Investigator
  
  Kondo Tadashi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Tsukuba
The development of novel therapeutic agents for liver cirrhosis using retinoic acid-modified adenosine encapsulating LiposomePrincipal Investigator
- Principal Investigator
  
  TAMURA Takafumi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Tsukuba
レチノイン酸修飾アデノシン封入リポソームを用いた肝硬変に対する新規治療薬の開発Principal Investigator
- Principal Investigator
  
  田村孝史
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Digestive surgery
- Research Institution
  University of Tsukuba
Development of new reagent for liver diseases using S1P and hyaluronic acid
- Principal Investigator
  
  OHKOHCHI NOBUHIRO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  University of Tsukuba

All 2021 2020 2019 2018 2016 2015 2014 2013 2012

All Journal Article Presentation Patent

[Journal Article] A novel hydrogel sheet prevents postoperative pancreatic fistula in a rat model2021
- Author(s)
  Akira Kemmochi, Takafumi Tamura, Yoshio Shimizu, Yohei Owada, Yusuke Ozawa, Katsuji Hisakura, Tatsuya Oda, Yayoi Kawano, Takehisa Hanawa, Nobuhiro Ohkohchi
- Journal Title
  
  Journal of Hepato-Biliary-Pancreatic Sciences
  
  Volume: Volume28, Issue2 Issue: 2 Pages: 192-201
- DOI
  10.1002/jhbp.867
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08641
[Journal Article] Oxidative stress and Liver X Receptor agonist induce hepatocellular carcinoma in Non‐alcoholic steatohepatitis model2020
- Author(s)
  Shimizu Yoshio、Tamura Takafumi、Kemmochi Akira、Owada Yohei、Ozawa Yusuke、Hisakura Katsuji、Matsuzaka Takashi、Shimano Hitoshi、Nakano Noriyuki、Sakashita Shingo、Oda Tatsuya、Ohkohchi Nobuhiro
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 36 Issue: 3 Pages: 800-810
- DOI
  10.1111/jgh.15239
- NAID
  120007165441
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21611, KAKENHI-PROJECT-20K21643, KAKENHI-PLANNED-17H06395, KAKENHI-PROJECT-18H04051, KAKENHI-PROJECT-18H03189, KAKENHI-PROJECT-19K09162
[Journal Article] Protecting liver sinusoidal endothelial cells suppresses apoptosis in acute liver damage.2016
- Author(s)
  Tanoi T, Tamura T, Sano N, Nakayama K, Fukunaga K, Zheng YW, Akhter A, Sakurai Y, Hayashi Y, Harashima H, Ohkohchi N.
- Journal Title
  
  Hepatol Res
  
  Volume: 未定 Issue: 7 Pages: 697-706
- DOI
  10.1111/hepr.12607
- NAID
  120007129460
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293296, KAKENHI-PROJECT-15K19870
[Journal Article] Kupffer cells have suppressive function for liver metastasis formation of colon cancer in early stage.2015
- Author(s)
  松村英樹, 近藤匡, 小川光一, 田村孝史, 福永潔, 大河内信弘.
- Journal Title
  
  Organ Biology
  
  Volume: 22 Issue: 2 Pages: 184-192
- DOI
  10.11378/organbio.22.184
- NAID
  130005142916
- ISSN
  1340-5152, 2188-0204
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462078
[Journal Article] Platelet transfusion improves liver function in patients with chronic liver disease and cirrhosis2013
- Author(s)
  Maruyama T, Murata S, Takahashi K, Tamura T, Nozaki R, Ikeda N, Fukuna ga K, Oda T, Sasaki R, Ohkohchi N
- Journal Title
  
  Tohoku J Exp Med
  
  Volume: 229(3) Pages: 213-20
- NAID
  10031161721
- Data Source
  KAKENHI-PROJECT-23390319
[Journal Article] Protective effect of heme oxygenase-1 on hepatic isch emia-reperfusion injury through inh ibition of platelet adhesion to the sinusoids2013
- Author(s)
  Tamura T, Kondo T, Ogawa K, Fukunag a K, Ohkohchi N
- Journal Title
  
  J Surg Res
  
  Volume: 180(1) Issue: 1 Pages: 62-72
- DOI
  10.1016/j.jss.2012.11.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390319, KAKENHI-PROJECT-23791480
[Journal Article] Platelet transfusion improves liver function in patients with chronic liver disease and cirrhosis.2013
- Author(s)
  Maruyama T, Murata S, Takahashi K, Tamura T, Nozaki R, Ikeda N, Fukunaga K, Oda T, Sasaki R, Ohkohchi N.
- Journal Title
  
  Tohoku J Exp Med
  
  Volume: 229(3) Pages: 213-220
- NAID
  10031161721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390319
[Journal Article] Protective effect of heme oxygenase-1 on hepaticischemia-reperfusion injury throughinhibition of platelet adhesion to the sinusoids2012
- Author(s)
  Tamura T, Kondo T, Ogawa K, Fukunaga K, Ohkohchi N.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 28(4) Issue: 4 Pages: 700-6
- DOI
  10.1111/jgh.12075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591499, KAKENHI-PROJECT-23390319, KAKENHI-PROJECT-24890032
[Journal Article] Interaction between Kupffer cells and platelets in the early period of hepatic ischemia-reperfusion injury--an in vivo study2012
- Author(s)
  Tamura T, Kondo T, Pak S, NakanoY, Murata S, Fukunaga K, Ohkohchi N
- Journal Title
  
  J Surg Res
  
  Volume: 178(1) Issue: 1 Pages: 443-51
- DOI
  10.1016/j.jss.2011.12.010
- NAID
  120007137160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591499, KAKENHI-PROJECT-23791480, KAKENHI-PROJECT-24890032
[Patent] スフィンゴシン 1 リン酸により修飾されたヒアルロン酸2014
- Inventor(s)
  原島秀吉, 兵藤守, 鳥谷部尚之, 大河内信弘, 田村孝史, 佐野直樹
- Industrial Property Rights Holder
  北海道大学, 筑波大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-043549
- Filing Date
  2014-03-06
- Data Source
  KAKENHI-PROJECT-23390319
[Presentation] 新規ハイドロゲル製剤の膵液瘻予防効果の検討2019
- Author(s)
  釼持明、田村孝史、久倉勝治
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K10489
[Presentation] 新規ハイドロゲル製剤の膵液瘻予防効果の検討2019
- Author(s)
  釼持明、田村孝史、久倉勝治
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K08641
[Presentation] 新規ハイドロゲル製剤を用いた膵切除術後の膵液瘻治療2018
- Author(s)
  釼持明、田村孝史、久倉勝治
- Organizer
  第73回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18K08641
[Presentation] 新規ハイドロゲル製剤を用いた膵切除術後の膵液瘻治療2018
- Author(s)
  釼持明、田村孝史、久倉勝治
- Organizer
  第73回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-16K10489
[Presentation] 新規ハイドロゲル製剤を用いた膵液瘻治療法の開発2018
- Author(s)
  釼持明、田村孝史、久倉勝治
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K08641
[Presentation] 新規ハイドロゲル製剤を用いた膵液瘻治療法の開発2018
- Author(s)
  釼持明、田村孝史、久倉勝治
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-16K10489
[Presentation] 血行性肝転移早期におけるKupffer細胞と腫瘍細胞の類洞内動態2015
- Author(s)
  松村英樹, 近藤匡, 小川光一, 田村孝史, 福永潔, 大河内信弘.
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-25462078
[Presentation] 肝類洞内皮細胞選択的アポトーシス抑制による急性肝障害治療の検討2015
- Author(s)
  田野井智倫, 田村孝史, 佐野直樹, 中山健, Afsana Akhter, 櫻井遊, 林泰弘, 原島秀吉, 大河内信弘
- Organizer
  第70回消化器外科学会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-15K19870
[Presentation] 新規Drug Dwlivery System を用いた肝類洞内皮細胞のアポトーシス抑制の急性肝障害における効果の検討2015
- Author(s)
  田野井智倫,田村孝史,佐野直樹,中山　健,福永　潔,村田聡一郎,Akhter A,櫻井　遊,林　泰弘,原島秀吉,大河内信弘
- Organizer
  第11回広島肝臓プロジェクト研究センターシンポジウム
- Place of Presentation
  ホテルグランヴィア広島（広島県広島市）
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-15K19870
[Presentation] リンパ球刺激による簡便で迅速な免疫抑制度判定2014
- Author(s)
  岩崎健一、村田聡一郎、小川光一、田村孝史、福永潔、本間真人、大河内信弘
- Organizer
  第41回日本臓器保存生物医学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター(豊中市）
- Year and Date
  2014-11-29
- Data Source
  KAKENHI-PROJECT-25461941
[Presentation] 肝虚血再潅流後早期における血小板の動態（Kupffer細胞との関係）2012
- Author(s)
  田村孝史
- Organizer
  第16回日本肝臓学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24890032
[Presentation] carbon monoxideによる肝虚血再潅流障害軽減メカニズムの解明2012
- Author(s)
  田村孝史
- Organizer
  第39回日本臓器保存生物医学会学術集会
- Place of Presentation
  福島
- Data Source
  KAKENHI-PROJECT-24890032

1. OHKOHCHI NOBUHIRO (40213673)

# of Collaborated Projects: 5 results

# of Collaborated Products: 8 results
2. FUKUNAGA Kiyoshi (20361339)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
3. Kondo Tadashi (00375495)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. 高橋一広 (80794528)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KOBAYASHI Akihiko (10446552)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MURATA Soichiro (40436275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. hisakura katsuji (60550168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. Zheng Yunwen (80404995)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 横川雅俊 (50447885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 本間真人 (90199589)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 小川光一 (20733637)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Matsumura Hideki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. FURUYA Kinji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. GE Jianyun

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. FURUTA Tomoaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SAKO Daisuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. IWASAKI Kinichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. LIU Liping

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. SHIMIZU Yoshio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. LIANG Chen

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SONG Dan

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. UCHIDA Yoshiaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. RAMIREZ R. Sabrina

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. YAGI Hiroya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. HAMADA Hiromi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. ISODA Hiroko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 島野仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAMURA Tamura 田村 孝史

Research Projects

Research Products

Co-Researchers

Analysis of carcinogenesis mechanism and development of novel therapeutic agents using a novel mouse model of NASH hepatocarcinogenesis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel method of prevention for pancreatic fistula using hydrogel sheetsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A novel hydrogel sheet prevents postoperative anastomotic leakage in a rat model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of the mechanisms of cancer cell attachment and infiltration to suppress liver metastasis, and development of its prophylaxis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Rat liver disease modeling with humanized liver and immune system

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Protecting liver sinusoidal endothelial cells suppresses apoptosis in acute liver damagePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ナノバイオ装置を用いた新規免疫抑制薬感受性試験の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

mechanism of liver metastasis focused on the interaction between tumor cells and Kupffer cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The development of novel therapeutic agents for liver cirrhosis using retinoic acid-modified adenosine encapsulating LiposomePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

レチノイン酸修飾アデノシン封入リポソームを用いた肝硬変に対する新規治療薬の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new reagent for liver diseases using S1P and hyaluronic acid

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A novel hydrogel sheet prevents postoperative pancreatic fistula in a rat model2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oxidative stress and Liver X Receptor agonist induce hepatocellular carcinoma in Non‐alcoholic steatohepatitis model2020

Author(s)

Journal Title

DOI

NAID

TAMURA Tamura 田村孝史