Mochizuki Kentaro 望月研太郎

Researcher Number	20633499
Other IDs	https://orcid.org/0000-0002-7624-9350
Affiliation (based on the past Project Information) *help	2017 – 2021: 東北大学, 医学系研究科, 大学院非常勤講師 2017: 東北大学, 医学(系)研究科(研究院), 助教 2016: 東北大学, 加齢医学研究所, 助教
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / General anatomy (including histology/embryology) Except Principal Investigator Dental engineering/Regenerative dentistry
Keywords	Principal Investigator 始原生殖細胞 / ヒストン修飾 / SETDB1 / HDAC3 / RNAiスクリーニング / エピゲノム / 多能性細胞 / エピブラスト / エピジェネティクス / 生殖細胞 … More / マウス / 胚発生 / 生殖系列遺伝子 / クロストーク / DNAメチル化 … More Except Principal Investigator 歯科医用工学 / 神経分化誘導 / 再生医歯学 / SH-SY5Y細胞 / N2A細胞 / 神経成長因子 / 骨形成タンパク質 / サブクローニング / 温熱刺激 / 神経細胞分化 / PC12細胞 Less

Epigenome dynamics in regulation of germ cell fate via histone modification crosstalkPrincipal Investigator
- Principal Investigator
  
  MOCHIZUKI Kentaro
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Tohoku University
Comprehensive identification and functional elucidation of regulators of histone modifications that regulate germ cell fatePrincipal Investigator
- Principal Investigator
  
  Mochizuki Kentaro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
Development of efficient and versatile method for inducing neuronal differentiation with temperature-controlled repeated thermal stimulation (TRTS)
- Principal Investigator
  
  Kudo Tada-aki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Tohoku University

All 2021 2019 2018 2017

All Journal Article Presentation

[Journal Article] Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing2021
- Author(s)
  Mochizuki K, Sharif J, Shirane K, Uranishi K, Bogutz AB, Janssen SM, Suzuki A, Okuda A, Koseki H, Lorincz MC.
- Journal Title
  
  Nature Communications
  
  Volume: 12(1) Issue: 1 Pages: 7020-7020
- DOI
  10.1038/s41467-021-27345-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16147, KAKENHI-PROJECT-17KK0185, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-19H03426, KAKENHI-PROJECT-21K06843
[Journal Article] SETDB1 is essential for mouse primordial germ cell fate determination by ensuring BMP signaling2018
- Author(s)
  Mochizuki Kentaro, Tando Yukio, Sekinaka Tamotsu, Otsuka Kei, Hayashi Yohei, Kobayashi Misato, Kamio Asuka, Ito-Matsuoka Yumi, Takehara Asuka, Kono Tomohiro, Osumi Noriko, Matsui Yasuhisa
- Journal Title
  
  Development
  
  Volume: 145 Issue: 23 Pages: 1-10
- DOI
  10.1242/dev.164160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K17594, KAKENHI-PROJECT-18K15001, KAKENHI-PROJECT-17J02039, KAKENHI-PROJECT-17K19372, KAKENHI-PROJECT-15H05579, KAKENHI-PUBLICLY-18H04875
[Journal Article] Repression of somatic genes by selective recruitment of HDAC3 by BLIMP1 is essential for mouse primordial germ cell fate determination2018
- Author(s)
  Mochizuki Kentaro, Hayashi Yohei, Sekinaka Tamotsu, Otsuka Kei, Ito-Matsuoka Yumi, Kobayashi Misato, Oki Shinya, Takehara Asuka, Kono Tomohiro, Osumi Noriko, Matsui Yasuhisa
- Journal Title
  
  Cell Reports
  
  Volume: 24 Issue: 10 Pages: 2682-2693
- DOI
  10.1016/j.celrep.2018.07.108
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17594, KAKENHI-PLANNED-16H06530, KAKENHI-PROJECT-17J02039, KAKENHI-PROJECT-17K19372, KAKENHI-PROJECT-15H05579, KAKENHI-PUBLICLY-18H04875, KAKENHI-PROJECT-18KT0024
[Presentation] 初期胚におけるポリコムPRC1.6複合体およびSETDB1による生殖系列遺伝子群の抑制はDNAメチル化を介したサイレンシングに先行する2021
- Author(s)
  望月研太郎
- Organizer
  科学研究費新学術領域「非ゲノム情報複製」第12回Webinar
- Invited
- Data Source
  KAKENHI-PROJECT-17KK0185
[Presentation] Role of histone methylation, and its reader proteins in DNA methylation and silencing of germline genome-defense genes.2019
- Author(s)
  Kentaro Mochizuki, Kevin Jeffers, Matthew C. Lorincz
- Organizer
  The 6th Canadian Conference on Epigenetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KK0185
[Presentation] Repression of somatic genes by selective recruitment of HDAC3 by BLIMP1 is essential for mouse primordial germ cell fate determination2018
- Author(s)
  Mochizuki Kentaro, Hayashi Yohei, Sekinaka Tamotsu, Otsuka Kei, Ito-Matsuoka Yumi, Kobayashi Misato, Oki Shinya, Takehara Asuka, Kono Tomohiro, Osumi Noriko, Lorincz Matthew, Matsui Yasuhisa
- Organizer
  The 5th Canadian Conference on Epigenetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17594
[Presentation] Hdac3 recruitment on somatic developmental genes by Blimp1 and their repression is essential for mouse primordial germ cell fate determination2017
- Author(s)
  Kentaro Mochizuki, Hisato Kobayashi, Yumi Matsuoka, Tomohiro Kono, Noriko Osumi, Yasuhisa Matsui
- Organizer
  日本発生生物学会第50回大会
- Data Source
  KAKENHI-PROJECT-17K17594

1. Kudo Tada-aki (50431606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 野口拓也 (20431893)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 冨並香菜子 (10815351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 出江紳一 (80176239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 金高弘恭 (50292222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 高木敏行 (20197065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 浦西洸介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mochizuki Kentaro 望月 研太郎

Research Projects

Research Products

Co-Researchers

Epigenome dynamics in regulation of germ cell fate via histone modification crosstalkPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive identification and functional elucidation of regulators of histone modifications that regulate germ cell fatePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of efficient and versatile method for inducing neuronal differentiation with temperature-controlled repeated thermal stimulation (TRTS)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Repression of germline genes by PRC1.6 and SETDB1 in the early embryo precedes DNA methylation-mediated silencing2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] SETDB1 is essential for mouse primordial germ cell fate determination by ensuring BMP signaling2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Repression of somatic genes by selective recruitment of HDAC3 by BLIMP1 is essential for mouse primordial germ cell fate determination2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] 初期胚におけるポリコムPRC1.6複合体およびSETDB1による生殖系列遺伝子群の抑制はDNAメチル化を介したサイレンシングに先行する2021

Author(s)

Organizer

Data Source

[Presentation] Role of histone methylation, and its reader proteins in DNA methylation and silencing of germline genome-defense genes.2019

Author(s)

Organizer

Data Source

[Presentation] Repression of somatic genes by selective recruitment of HDAC3 by BLIMP1 is essential for mouse primordial germ cell fate determination2018

Author(s)

Organizer

Data Source

[Presentation] Hdac3 recruitment on somatic developmental genes by Blimp1 and their repression is essential for mouse primordial germ cell fate determination2017

Author(s)

Organizer

Data Source

Mochizuki Kentaro 望月研太郎