Taguchi Akihiko 田口昭彦

… Alternative Names

田口昭彦タグチアキヒコ

TAGUCHI Akihiko 田口昭彦

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Researcher Number	20634744
Other IDs
Affiliation (Current)	2025: 山口大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2023: 山口大学, 医学部附属病院, 講師 2018 – 2021: 山口大学, 大学院医学系研究科, 助教 2014 – 2016: 山口大学, 医学(系)研究科(研究院), 助教 2013: 山口大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 49010:Pathological biochemistry-related / Basic Section 54040:Metabolism and endocrinology-related / Metabolomics Except Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Experimental pathology / Pathological medical chemistry
Keywords	Principal Investigator E4BP4 / Wolfram症候群 / 出力系時計遺伝子 / 炎症性腸疾患 / マクロファージ / 概日リズム / 時計遺伝子 / Wolfram症候 / 糖尿病 / 小胞体ストレス / 全エキソーム解析 / 原因遺伝子 … More Except Principal Investigator … More インスリン分泌 / 膵β細胞 / 概日リズム / 時計遺伝子 / 体内時計 / ウォルフラム症候群 / 小胞体ストレス / インスリン / 糖尿病 / 糖代謝 / サーカディアンリズム / E4BP4 / DBP / 視神経萎縮 / 脱分化 / DBPシグナル / 生体リズム / 2型糖尿病 / β細胞 / Wolfram症候群 / ストレス / アポトーシス Less

出力系時計遺伝子に着目した炎症性腸疾患の病態解明と治療法の展開Principal Investigator
- Principal Investigator
  
  田口昭彦
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Yamaguchi University
From Cellular Stress to beta-cell failure and insulin resistance: Investigation of new mechanisms
- Principal Investigator
  
  Tanizawa Yukio
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Yamaguchi University
Identification and treatment of targets that cause beta cell death by Wolfram SyndromePrincipal Investigator
- Principal Investigator
  
  Taguchi Akihiko
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Yamaguchi University
glucose metabolism in pancrateic beta-cell via circadian clock genes DBP and E4BP4
- Principal Investigator
  
  OHTA Yasuharu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Yamaguchi University
膵β細胞死および神経細胞死に共通する新たな原因遺伝子の同定Principal Investigator
- Principal Investigator
  
  田口昭彦
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Yamaguchi University
Investigation of the mechanism of beta-cell failure in diabetes using Wolfram Syndrome as a model
- Principal Investigator
  
  TANIZAWA Yukio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Yamaguchi University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Effects of pemafibrate on left ventricular diastolic function in patients with type 2 diabetes mellitus: a pilot study2023
- Author(s)
  Yamamoto Kaoru、Ohta Yasuharu、Taguchi Akihiko、Akiyama Masaru、Nakabayashi Hiroko、Nagao Yuko、Ryoko Hatanaka、Wada Yasuaki、Yamamoto Takeshi、Yano Masafumi、Tanizawa Yukio
- Journal Title
  
  Diabetology International
  
  Volume: 14 Issue: 4 Pages: 434-439
- DOI
  10.1007/s13340-023-00645-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08626, KAKENHI-PROJECT-23K06401, KAKENHI-PROJECT-21K08054
[Journal Article] Metabolic state switches between morning and evening in association with circadian clock in non‐diabetic humans2022
- Author(s)
  Fujimoto Ruriko、Ohta Ysuharu、Masuda Konosuke、Taguchi Akihiko、Akiyama Masaru、Yamamoto Kaoru、Nakabayashi Hiroko、Nagao Yuko、Matsumura Takuro、Hiroshige Syunsuke、Kajimura Yasuko、Akashi Makoto、Tanizawa Yukio
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: - Issue: 9 Pages: 1496-1505
- DOI
  10.1111/jdi.13810
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09006, KAKENHI-PROJECT-19H03710, KAKENHI-PROJECT-22K08626
[Journal Article] P2Y1 purinergic receptor identified as a diabetes target in a small-molecule screen to reverse circadian β-cell failure2022
- Author(s)
  Marcheva B, Weidemann BJ, Taguchi A, Perelis M, Ramsey KM, Newman MV, Kobayashi Y, Omura C, Manning Fox JE, Lin H, Macdonald PE, Bass J.
- Journal Title
  
  Elife
  
  Volume: 21
- DOI
  10.7554/elife.75132
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08517
[Journal Article] Liver-specific dysregulation of clock-controlled output signal impairs energy metabolism in liver and muscle2021
- Author(s)
  Matsumura T, Ohta Y, Taguchi A, Hiroshige S, Kajimura Y, Fukuda N, Yamamoto K, Nakabayashi H, Fujimoto R, Yanai A, Shinoda K, Watanabe K, Mizukami Y, Kanki K, Shiota G, Tanizawa Y.
- Journal Title
  
  Biochem Biophys Res Commun .
  
  Volume: 534 Pages: 415-421
- DOI
  10.1016/j.bbrc.2020.11.066
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08517, KAKENHI-PROJECT-19K02318, KAKENHI-PROJECT-19K09006, KAKENHI-PROJECT-18K16255, KAKENHI-PROJECT-20K22781, KAKENHI-PROJECT-19H03710, KAKENHI-PROJECT-18K11128, KAKENHI-PROJECT-21K08644
[Journal Article] Adrenomedullin has a cytoprotective role against endoplasmic reticulum stress for pancreatic β‐cells in autocrine and paracrine manners2020
- Author(s)
  Suetomi Risa、Ohta Yasuharu、Akiyama Masaru、Matsumura Takuro、Taguchi Akihiko、Yamamoto Kaoru、Kamatani Takashi、Tanizawa Yukio
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: - Issue: 4 Pages: 823-833
- DOI
  10.1111/jdi.13218
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08517, KAKENHI-PROJECT-19K09006, KAKENHI-PROJECT-19H03710
[Journal Article] 【インスリン分泌機構とその異常】時計遺伝子とインスリン分泌異常について2020
- Author(s)
  田口昭彦, 谷澤幸生
- Journal Title
  
  月刊糖尿病
  
  Volume: 12(7) Pages: 40-46
- Data Source
  KAKENHI-PROJECT-19H03710
[Journal Article] 時計遺伝子と糖代謝2020
- Author(s)
  田口昭彦, 太田康晴, 谷澤幸生
- Journal Title
  
  日本体質医学会雑誌
  
  Volume: 82(2) Pages: 73-82
- NAID
  40022281033
- Data Source
  KAKENHI-PROJECT-19H03710
[Journal Article] Molecular clock as a regulator of β-cell function2018
- Author(s)
  Taguchi Akihiko、Ohta Yasuharu、Tanizawa Yukio
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 9 Issue: 3 Pages: 453-456
- DOI
  10.1111/jdi.12835
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04849, KAKENHI-PROJECT-18K08517
[Journal Article] Clock Gene Dysregulation Induced by Chronic ER Stress Disrupts β-cell Function.2017
- Author(s)
  Ohta Y., Taguchi A., Matsumura T., Nakabayashi H., Akiyama M., Yamamoto K., Fujimoto R., Suetomi R., Yanai A., Shinoda K., Tanizawa Y.
- Journal Title
  
  EBioMedicine
  
  Volume: 18 Pages: 146-156
- DOI
  10.1016/j.ebiom.2017.03.040
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04849, KAKENHI-PROJECT-26460489, KAKENHI-PROJECT-16H05118
[Journal Article] Wolfram syndrome in the Japanese population; molecular analysis of WFS1 gene and characterization of clinical features.2014
- Author(s)
  Matsunaga K, Tanabe K, Inoue H, Okuya S, Ohta Y, Akiyama M, Taguchi A, Kora Y, Okayama N, Yamada Y, Wada Y, Amemiya S, Sugihara S, Nakao Y, Oka Y, Tanizawa Y.
- Journal Title
  
  PLoS One
  
  Volume: 9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460489
[Journal Article] Wolfram syndrome in the Japanese Population; Molecular Analysis of WFS1 gene and Characterization of Clinical Features2014
- Author(s)
  Kimie Matsunaga, Akihiko Taguchi, Yukio Tanizawa,et al.
- Journal Title
  
  PLOS ONE
  
  Volume: 9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860696
[Journal Article] Clock-controlled output gene Dbp is a regulator of Arnt/Hif-1β gene expression in pancreatic islet β-cells2013
- Author(s)
  Nakabayashi H, Ohta Y, Yamamoto M, Susuki Y, Taguchi A, Tanabe K, Kondo M, Hatanaka M, Nagao Y, Tanizawa Y
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 434 Issue: 2 Pages: 370-5
- DOI
  10.1016/j.bbrc.2013.03.084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590984, KAKENHI-PROJECT-23390080, KAKENHI-PROJECT-25461357
[Journal Article] Clock-controlled output gene Dbp is a regulator of Arnt/Hif-1 β gene expression in pancreatic islet β -cells2013
- Author(s)
  Nakabayashi H., Ohta Y., Yamamoto M., Susuki Y., Taguchi A., Tanabe K., Kondo M.,Hatanaka M., Nagao Y., Tanizawa Y.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 434(2) Pages: 370-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] スダチチンは高グルコース条件においてインスリン分泌を促進する2023
- Author(s)
  畠中諒子、田口昭彦、増田香之介、永尾優子、太田康晴、谷澤幸生
- Organizer
  第66回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-23K06401
[Presentation] 出力系時計遺伝子DBPの欠損により骨格筋のインスリン感受性の日内変動が消失する2023
- Author(s)
  太田康晴, 田口昭彦, 廣重俊典, 梶邑泰子, 淀川千佳, 藤岡侑香, 畠中諒子, 松村卓郎, 谷澤幸生
- Organizer
  第66回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-23K06401
[Presentation] Txnip preserves brown fat innate thermogenic capacity2023
- Author(s)
  鄒朦, 田部勝也, 椎木幾久子, 河野大輔, 香川正太, 田口昭彦, 池田賢司, 山田哲也, 奥屋茂, 北村忠弘, 増谷弘, 谷澤幸生
- Organizer
  第34回分子糖尿病学シンポジウムプログラム
- Data Source
  KAKENHI-PROJECT-23K06401
[Presentation] 骨格筋インスリン感受性における出力系時計遺伝子DBPの役割の解明2023
- Author(s)
  田口昭彦、藤岡侑香、淀川千佳、廣重俊典、梶邑泰子、畠中諒子、永尾優子、谷澤幸生、太田康晴
- Organizer
  第38回日本糖尿病合併症学会年次学術集会
- Data Source
  KAKENHI-PROJECT-23K06401
[Presentation] ペマフィブラートが2型糖尿病患者の左室拡張能に与える効果の検討2022
- Author(s)
  太田康晴，田口昭彦，秋山優，山本薫，中林容子，廣重俊典，畠中諒子，和田靖明，山本健，矢野雅文，谷澤幸生
- Organizer
  第６５回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] Txnip preserves brown fat innate thermogenic activity2022
- Author(s)
  MENG ZOU，田部勝也，椎木幾久子，田口昭彦，河野大輔，北村忠弘，奥屋茂，増谷弘，谷澤幸生
- Organizer
  第６５回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] スダチチンによるインスリン分泌促進機構の解明2022
- Author(s)
  畠中諒子，田口昭彦，増田香之介，尾野孝夫，對馬千沙都，二階堂隆人，高岡彰子，太田康晴，谷澤幸生
- Organizer
  第６５回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 非糖尿病者における糖代謝の概日リズムに基づいた時計遺伝子モニタリングの有用性の検討2021
- Author(s)
  藤本留理子，太田康晴，松村卓郎，田口昭彦，山本薫，廣重俊典，秋山優，竹田孔明，明石真，谷澤幸生
- Organizer
  第２０回日本先進糖尿病治療研究会　第１８回１型糖尿病研究会（合同開催）
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 糖尿病基礎研究最前線　「時計遺伝子による代謝制御はどこまで糖尿病に関わっているのか」を探求する2021
- Author(s)
  太田康晴，田口昭彦，松村卓郎，藤本留理子，中林容子，廣重俊典，梶邑泰子，山本薫，神吉けい太，汐田剛史，明石真，谷澤幸生
- Organizer
  第６４回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 出力系時計遺伝子Dbpを欠損したマウスでは骨格筋のインスリン感受性の亢進を認める2021
- Author(s)
  廣重俊典，太田康晴，田口昭彦，山本薫，松村卓郎，梶邑泰子，谷澤幸生
- Organizer
  第７１回日本体質医学会総会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 出力系時計遺伝子DBPの欠損は骨格筋のインスリン感受性を亢進させる2021
- Author(s)
  廣重俊典，太田康晴，田口昭彦，山本薫，松村卓郎，梶邑泰子，藤本留理子，谷澤幸生
- Organizer
  第６４回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 非糖尿病者における糖代謝の概日リズムとそのメカニズムの検討2020
- Author(s)
  藤本留理子，太田康晴，松村卓郎，田口昭彦，山本薫，廣重俊典，秋山優，竹田孔明，明石真，谷澤幸生
- Organizer
  第63回　日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] ヒトにおける糖代謝の概日リズムと時計遺伝子との関連性の検討2020
- Author(s)
  松村卓郎，太田康晴，藤本留理子，田口昭彦，山本薫，廣重俊典，竹田孔明，明石真，谷澤幸生
- Organizer
  第63回　日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 時計遺伝子E4BP4によるマクロファージの炎症制御機構の解明2020
- Author(s)
  梶邑泰子, 田口昭彦, 山本薫, 太田康晴, 谷澤幸生
- Organizer
  第70回日本体質医学会総会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 出力系時計遺伝子E4BP4の肝特異的過剰発現は骨格筋でのインスリン感受性を低下させる2020
- Author(s)
  太田康晴，松村卓郎，田口昭彦，福田尚文，山本薫，柳井章江，秋山優，藤本留理子，神吉けい太，汐田剛史，水上洋一，篠田晃，谷澤幸生
- Organizer
  第63回　日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 体内時計による代謝制御と糖尿病2020
- Author(s)
  太田康晴，田口昭彦，松村卓郎，藤本留理子，秋山優，福田尚文，山本薫，神吉けい太，汐田剛史，水上洋一，篠田晃，柳井章江，明石真，谷澤幸生
- Organizer
  第63回　日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 健常者における糖代謝の概日リズムとそのメカニズムの検討2020
- Author(s)
  藤本留理子, 太田康晴, 松村卓郎, 田口昭彦, 山本薫, 廣重俊典, 秋山優, 竹田孔明, 明石真, 谷澤幸生
- Organizer
  第93回日本内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 体内時計と代謝制御機構2019
- Author(s)
  太田康晴、田口昭彦、松村卓郎、福田尚文、山本薫、柳井章江、秋山優、藤本留理子、神吉けい太、汐田剛史、水上洋一、篠田晃、谷澤幸生
- Organizer
  第69回日本体質医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 小胞体ストレス下における膵β細胞での時計遺伝子E4BP4, DBPの役割2019
- Author(s)
  田口昭彦
- Organizer
  第62回糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K08517
[Presentation] 健康成人の糖代謝の概日リズムとそのメカニズムの解明2019
- Author(s)
  藤本留理子、太田康晴、松村卓郎、田口昭彦、山本　薫、廣重俊典、秋山優、竹田孔明、明石真、谷澤幸生
- Organizer
  日本糖尿病学会中国四国地方会第57回総会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] New messengers in β-cell function：Physiology and pathophysiology　WFS1 and β-cell function2019
- Author(s)
  谷澤幸生、太田康晴、田部勝也、田口昭彦、椎木幾久子、秋山優、幡中雅行
- Organizer
  第62回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 筋・脂肪・肝のインスリン作用　出力系時計遺伝子 DBP, E4BP4を介した肝臓における脂質代謝制御機構2019
- Author(s)
  太田康晴、松村卓郎、田口昭彦、福田尚文、山本薫、柳井章江、秋山優、藤本留理子、神吉けい太、汐田剛史、水上洋一、篠田晃、谷澤幸生
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 時計遺伝子 E4BP4, DBPと膵β細胞機能との関連2019
- Author(s)
  田口昭彦、太田康晴、松村卓郎、梶邑泰子、山本薫、中林容子、藤本留理子、秋山優、末冨吏佐、柳井章江、篠田晃、谷澤幸生
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19H03710
[Presentation] 時計遺伝子E4BP4を介する肝臓でのエネルギー代謝調節機構の解明2018
- Author(s)
  田口　昭彦
- Organizer
  第68回日本体質医学会総会
- Data Source
  KAKENHI-PROJECT-18K08517
[Presentation] 時計遺伝子E4BP4/DBPの膵β細胞における役割の解明2018
- Author(s)
  田口　昭彦
- Organizer
  日本糖尿病学会中国四国地方会第56回総会
- Data Source
  KAKENHI-PROJECT-18K08517
[Presentation] Circadian Dysregulationによる肝インスリン抵抗性と肝脂質代謝異常2018
- Author(s)
  田口　昭彦
- Organizer
  第33回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-18K08517
[Presentation] Clock gene dysreguration induced by chronic ER stress disrupts β-cell function2016
- Author(s)
  Yasuharu Ohta, Akihiko Taguchi, Takuro Matsumura, Hiroko Nakabayashi, Masaru Akiyama, Risa Suetomi, Akie Yanai, Koh Shinoda, Yukio Tanizawa
- Organizer
  The Islet Study Group meeting 2016
- Place of Presentation
  Riessersee Hotel Resort, Garmisch-Partenkirchen, Germany
- Year and Date
  2016-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460489
[Presentation] 肝細胞特異的E4BP4過剰発現マウスを用いた時計遺伝子を介する新たな肝臓の糖代謝調節機構の解明2016
- Author(s)
  松村卓郎、太田康晴、田口昭彦、中林容子、秋山　優、末冨吏佐、山本薫、谷澤幸生、神吉けい太、汐田剛史
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26460489
[Presentation] DBPシグナルによるインスリン分泌調節機構の解明2016
- Author(s)
  太田康晴、田口昭彦、松村卓郎、中林容子、秋山　優、末富吏佐、谷澤幸生
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26460489
[Presentation] 肝細胞特異的E4BP4過剰発現マウスを用いた時計遺伝子を介する新たな肝臓の糖代謝調節機構の解明2016
- Author(s)
  松村卓郎、太田康晴、田口昭彦、中林容子、福田尚文、秋山　優、末冨吏佐、山本薫、谷澤幸生、神吉けい太、汐田剛史
- Organizer
  第３回肝臓と糖尿病代謝研究会
- Place of Presentation
  金沢市石川県立音楽堂
- Data Source
  KAKENHI-PROJECT-26460489
[Presentation] 膵β細胞におけるDBPシグナルはfirst meal摂取時の鋭敏なインスリン分泌にとって重要である2016
- Author(s)
  松村卓郎、太田康晴、田口昭彦、中林容子、秋山優、末冨吏佐、山本薫、谷澤幸生
- Organizer
  第59回日本内分泌学会学術総会
- Place of Presentation
  京都府京都市京都国際会館
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26460489
[Presentation] Clock gene dysregulation induced by chronic endoplasmic reticulum stress disrupts β-cell function2016
- Author(s)
  Yasuharu Ohta, Akihiko Taguchi, Takuro Matsumura, Hiroko Nakabayashi, Masaru Akiyama, Risa Suetomi, Akie Yanai, Koh Shinoda, Yukio Tanizawa
- Organizer
  11th IDF-WPR Congress & 8th AASD Scientific Meeting
- Place of Presentation
  Taipei International Convention Center, Taipei, Taiwan
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460489
[Presentation] 肝細胞特異的E4BP4過剰発現マウスを用いた時計遺伝子を介する糖代謝調節機構の解明2016
- Author(s)
  松村卓郎、太田康晴、田口昭彦、福田尚文、秋山優、末冨吏佐、山本薫、谷澤幸生、神吉けい太、汐田　剛史
- Organizer
  日本糖尿病学会中国四国地方会第54回総会
- Place of Presentation
  高知県立県民文化ホール
- Year and Date
  2016-11-11
- Data Source
  KAKENHI-PROJECT-26460489
[Presentation] DBP/E4BP4 plays a pivotal role in circadian regulation of β-cell function2015
- Author(s)
  Ohta Y., Taguchi A., Akiyama M., Nakabayashi H., Suetomi R., Yanai A., Shinoda K., Tanizawa Y.
- Organizer
  16th Servier-IGIS (International Group on Insulin Secretion) symposium
- Place of Presentation
  St. Jean Cap Ferrat, France
- Year and Date
  2015-04-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460489
[Presentation] 膵β細胞特異的E4BP4過剰発現マウスを用いた時計遺伝子を介するインスリン分泌調節機構の解明2015
- Author(s)
  太田康晴、松村卓郎、田口昭彦、秋山優、中林容子、末冨吏佐、柳井章江、篠田晃、谷澤幸生
- Organizer
  第65回日本体質医学会総会
- Place of Presentation
  北海道札幌市札幌コンベンションセンター
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-26460489
[Presentation] DBPシグナルはグルコース応答性のインスリン分泌とりわけfirst meal摂取時のインスリン分泌にとって重要である2015
- Author(s)
  松村卓郎、太田康晴、田口昭彦、中林容子、秋山　優、末冨吏佐、谷澤幸生
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  山口県下関市　シーモールホール
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26460489
[Presentation] 全エキゾーム解析による Wolfram 症候群の新たな原因遺伝子同定の試み2014
- Author(s)
  田口昭彦,田部勝也,松永仁恵,太田康晴,細道一善,井ノ上逸朗,谷澤幸生
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] 時計遺伝子DBP/E4BP4 による膵 β 細胞機能調節2014
- Author(s)
  田口昭彦,太田康晴,山本将義,薄陽祐,中林容子,谷澤幸生
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] 膵 β 細胞特異的E4BP4 過剰発現マウスを用いた時計遺伝子を介する新たなインスリン分泌調節機構の解明2014
- Author(s)
  太田康晴,田口昭彦,中林容子,秋山優,末冨吏佐,谷澤幸生
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] 次世代シーケンサーによるWolfram症候群の新たな原因遺伝子同定の試み2014
- Author(s)
  田口昭彦
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-26860696
[Presentation] 時計遺伝子DBP/E4BP4による膵β細胞機能調節2014
- Author(s)
  田口昭彦
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-26860696
[Presentation] Clock-controlled output gene Dbp is a regulator of Arnt/Hif- 1β gene expression in pancreatic islet β-cells2013
- Author(s)
  Tanizawa Y., Nakabayashi H., Ohta Y., Yamamoto M., Susuki Y., Taguchi A., Tanabe K., Kondo M., Hatanaka M., Nagao Y.
- Organizer
  EASD ISLET STUDY GROUP ANNUAL MEETING 2013 (Beta-cell Regeneration and Genome Regulation)
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Clock-Controlled Output Gene Dbp is a Regulator of Arnt/Hif-1β Gene Expression in Pancreatic Islet β-Cells.2013
- Author(s)
  Nakabayashi H., Ohta Y., Yamamoto M., Susuki Y., Taguchi A., Tanabe K., Kondo M., Hatanaka M., Nagao Y., Tanizawa Y.
- Organizer
  73th Annual Meeting and Scientific Sessions of the American Diabetes Association
- Place of Presentation
  Chicago, IL, USA.
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Clock-controlled output gene Dbp is a regulator of Arnt/Hif-1βgene expression in pancreatic islet β-cells.2013
- Author(s)
  Tanizawa Y., Nakabayashi H., Ohta Y., Yamamoto M., Susuki Y., Taguchi A., Tanabe K., Kondo M., Hatanaka M., Nagao Y.
- Organizer
  EASD ISLET STUDY GROUP ANNUAL MEETING 2013
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] Clock-Controlled Output Gene Dbp is a Regulator of Arnt/Hif-1β Gene Expression in Pancreatic Islet β-Cells2013
- Author(s)
  Nakabayashi H., Ohta Y., Yamamoto M., Susuki Y., Taguchi A., Tanabe K., Kondo M., Hatanaka M., Nagao Y., Tanizawa Y
- Organizer
  73th Annual Meeting and Scientific Sessions of the American Diabetes Association
- Place of Presentation
  Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-23390080
[Presentation] 時計遺伝子DBP/E4BP4による膵β細胞機能調節
- Author(s)
  田口昭彦　太田康晴　山本将義　薄陽祐　中林容子　谷澤幸生
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡サンパレス（福岡市）
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26460489
[Presentation] DBP/E4BP4 signaling has a pivotal role in the development of beta-cell failure caused by circadian disruption
- Author(s)
  Yasuharu Ohta, Takuro Matsumura, Akihiko Taguchi, Hiroko Nakabayashi, Masaru Akiyama, Risa Sutomi, Akie Yanai, Kou Shinoda, Yukio Tanizawa
- Organizer
  THE 10TH IDF-WPR CONGRESS AND 6TH AASD SCIENTIFIC MEETING
- Place of Presentation
  Suntec, Singapore
- Year and Date
  2014-11-21 – 2014-11-24
- Data Source
  KAKENHI-PROJECT-26460489
[Presentation] 膵β細胞特異的E4BP4過剰発現マウスを用いた時計遺伝子を介する新たなインスリン分泌調節機構
- Author(s)
  太田康晴　田口昭彦　中林容子　秋山優　末富吏佐　谷澤幸生
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場（大阪市）
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26460489
[Presentation] DBP/E4BP4 signaling plays a pivotal role in the development of beta-cell failure caused by circadian disruption
- Author(s)
  Yasuharu Ohta, Akihiko Taguchi, Hiroko Nakabayashi, Masaru Akiyama, Takuro Matsumura, Risa Suetomi, Akie Yanai, Kou Shinoda, Yukio Tanizawa
- Organizer
  Islet Study Group Meeting-IGS2014
- Place of Presentation
  Lausanne, Switzerland
- Year and Date
  2014-09-12 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-26460489
[Presentation] 3種類のDPP4阻害薬の使用状況および血糖改善に寄与する因子の検討
- Author(s)
  永尾優子、田口昭彦、太田康晴、奥屋　茂、谷澤幸生、山口県CHOUSHU-5研究会
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場（大阪市）
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26460489
[Presentation] 全エキソーム解析によるWolfram症候群の新たな原因遺伝子同定の試み
- Author(s)
  田口昭彦　田部勝也　松永仁恵　太田康晴　細道一善　井上逸郎　谷澤幸生
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場（大阪市）
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26460489

1. OHTA Yasuharu (60448280)

# of Collaborated Projects: 4 results

# of Collaborated Products: 50 results
2. TANIZAWA Yukio (00217142)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TANABE Katsuya (00397994)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. 秋山優 (90717547)

# of Collaborated Projects: 2 results

# of Collaborated Products: 28 results
5. 幡中雅行 (60572534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. 柴田健輔 (50529972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 富永直臣 (90891507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 谷沢幸生

# of Collaborated Projects: 0 results

# of Collaborated Products: 30 results

Taguchi Akihiko 田口 昭彦

田口 昭彦 タグチ アキヒコ

TAGUCHI Akihiko 田口 昭彦

Research Projects

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Co-Researchers

出力系時計遺伝子に着目した炎症性腸疾患の病態解明と治療法の展開Principal Investigator

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From Cellular Stress to beta-cell failure and insulin resistance: Investigation of new mechanisms

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Identification and treatment of targets that cause beta cell death by Wolfram SyndromePrincipal Investigator

Principal Investigator

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glucose metabolism in pancrateic beta-cell via circadian clock genes DBP and E4BP4

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膵β細胞死および神経細胞死に共通する新たな原因遺伝子の同定Principal Investigator

Principal Investigator

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Investigation of the mechanism of beta-cell failure in diabetes using Wolfram Syndrome as a model

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[Journal Article] Effects of pemafibrate on left ventricular diastolic function in patients with type 2 diabetes mellitus: a pilot study2023

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[Journal Article] Metabolic state switches between morning and evening in association with circadian clock in non‐diabetic humans2022

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[Journal Article] P2Y1 purinergic receptor identified as a diabetes target in a small-molecule screen to reverse circadian β-cell failure2022

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[Journal Article] Liver-specific dysregulation of clock-controlled output signal impairs energy metabolism in liver and muscle2021

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[Journal Article] Adrenomedullin has a cytoprotective role against endoplasmic reticulum stress for pancreatic β‐cells in autocrine and paracrine manners2020

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[Journal Article] 【インスリン分泌機構とその異常】時計遺伝子とインスリン分泌異常について2020

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[Journal Article] 時計遺伝子と糖代謝2020

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NAID

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[Journal Article] Molecular clock as a regulator of β-cell function2018

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DOI

Taguchi Akihiko 田口昭彦

田口昭彦タグチアキヒコ

TAGUCHI Akihiko 田口昭彦

[Presentation] 糖尿病基礎研究最前線　「時計遺伝子による代謝制御はどこまで糖尿病に関わっているのか」を探求する2021