WATANABE TAKEHISA 渡邊丈久

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WATANABE Takehisa 渡邊丈久

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Researcher Number	20634843
Other IDs
Affiliation (Current)	2025: 熊本大学, 大学院生命科学研究部(医), 助教
Affiliation (based on the past Project Information) *help	2016 – 2024: 熊本大学, 大学院生命科学研究部(医), 助教 2012 – 2016: 熊本大学, 生命科学研究部, 助教 2014 – 2015: 熊本大学, その他の研究科, 助教 2014: 熊本大学, 生命科学研究部(医), 助教 2012: 熊本大学, 大学院・生命科学研究部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator エピジェネティックス / cccDNA / HBV / エピゲノム / exosome / Chromatin IP / Regulatory Element / Exosome / 肝発癌 / 脂質代謝異常 … More / HCV / 代謝異常 / 癌 / SVR / DAAs / miRNA / B型肝炎ウイルス / 遺伝子型 / エンハンサー / ｴﾋﾟｹﾞﾉﾑ / 予後予測 / 発現制御 / 遺伝子 / ゲノム / epigenetics / CTCF / NF-κB / LTβ … More Except Principal Investigator 治療抵抗性 / 大腸癌 / 代謝リプログラミング / ﾌﾟﾛﾃｵﾐｸｽ / 肝癌 / プロテオミクス / 肝発癌 / マルチオミクス解析 / 分子標的治療薬 / Wnt経路 / Wnt / エピジェネテイクス / 遺伝子解析 / 細胞死抵抗性 / 翻訳後修飾 / 空間的遺伝子発現解析 / コリン欠乏高脂肪食 / 背景大腸粘膜 / AOM-DSS / 肝腫瘍 / 炎症性発癌 / エピゲノム制御薬 / マイクロRNA / 肝発癌進展 / NASH / 脂質代謝 / エピゲノム / 肝癌細胞 / 栄養環境 / LSD2 / STC2 / 脂肪肝 / 小胞体ストレス / 酸化ストレス / 栄養・代謝環境 / エピゲノム制御 / メダボローム解析 / メタボローム / メタボローム解析 / 転写因子 / ヒストン脱メチル化酵素 / 原発性肝癌 / オミクス解析 / 効果予測マーカー / 細胞環境 / 予後 / 抵抗性 / 感受性 / 化学療法 / バイオインフォマティクス / CLU / 分子標的治療 / NR-index / Clusterin / バイオマーカー / ソラフェニブ / 肝細胞癌 / 下部消化管学 / EMT / ｑPCR / 大腸癌発癌 / Cdh1 / 内視鏡治療 / SSAP / miRNA / 消化器 / 内視鏡 / 大腸ポリープ / 発癌 / 浸潤・転移 / 燐酸化 / 内科 / 癌 / マルチオミクス / バイオインフォマテイクス / 微小環境 / トランスクリプトーム / 細胞周期 / ﾄﾗﾝｽｸﾘﾌﾟﾄｰﾑ / 肝再生 / 遺伝子解 Less

Elucidation of Different cccDNA Control Mechanisms Among HBV Genotypes Using Novel Epigenomic Analysis TechniquesPrincipal Investigator
- Principal Investigator
  
  渡邊丈久
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kumamoto University
the analysis of the regulatory mechanism in HBV-cccDNA using a new epigenetic methodPrincipal Investigator
- Principal Investigator
  
  WATANABE TAKEHISA
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kumamoto University
Elucidation of nutrition-induced epigenetic changes in hepatocytes and their application to the regulation of hepatocellular carcinoma development and progression.
- Principal Investigator
  
  SASAKI Yutaka
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kumamoto University
  Nagasaki International University
Clarification of Cdh1 mediated inflammatory carcinogenesis mechanism revealed by spatial gene expression analysis and development of novel preventive strategies.
- Principal Investigator
  
  Naoe Hideaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kumamoto University
Investigation on prediction for medical treatment response to advanced hepatocellular carcinoma
- Principal Investigator
  
  Tanaka Motohiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kumamoto University
The impact of the changes in serum exosomal miRNA profiles induced by DAAs therapy on liver carcinogenesisPrincipal Investigator
- Principal Investigator
  
  Watanabe Takehisa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kumamoto University
Analysis of metabolic reprogramming induced by cellular environment and its application to control hepato-carcinogenesis
- Principal Investigator
  
  SASAKI YUTAKA
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kumamoto University
Regulation of invasion and metastasis of colon cancer via Wnt-Cdh1 axis
- Principal Investigator
  
  Naoe Hideaki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kumamoto University
The role of Cdh1 in colorectal cancer invasion and metastasis
- Principal Investigator
  
  Naoe Hideaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kumamoto University
molecular biological analysis of Sessile serrated adenoma/polyp in the proximal colon
- Principal Investigator
  
  Shono Takashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kumamoto University
Analysis of microenvironment-mediated treatment resistance of hepatocellular carcinoma in terms of integrated proteomics
- Principal Investigator
  
  Sasaki Yutaka
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kumamoto University
Analysis of the higher-order regulatory mechanism of LT-beta epigenome, leading to clinical application.Principal Investigator
- Principal Investigator
  
  WATANABE TAKEHISA
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kumamoto University
Basic study of the cell cycle related molecules affiliated with liver regeneration and clinical application
- Principal Investigator
  
  NAGAHAMA Hiroyasu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kumamoto University
Analysis of mechanisms underlying treatment-resistance ofhepatocelluar carcinoma in the point view of post-translationalmodification evaluated by proteomics
- Principal Investigator
  
  SASAKI Yutaka
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kumamoto University

[Book] 最新医学別冊改訂第2版（新しい診断と治療ABC, 44 肝硬変)2013
- Author(s)
  渡邊丈久、田中基彦、佐々木裕
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-25293173
[Book] 専門医のための消化器病学第2版(肝細胞癌と癌幹細胞）2013
- Author(s)
  渡邊丈久、佐々木裕
- Total Pages
  686
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-25293173
[Book] 肝細胞癌と癌幹細胞.2013
- Author(s)
  渡邊丈久、佐々木裕.
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-25860543
[Book] Hepatology practice 第2巻(アルコール性肝障害と肝炎ウイルス）2013
- Author(s)
  渡邊丈久、佐々木裕
- Total Pages
  399
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-25293173
[Book] アルコール性肝障害と肝炎ウイルス.2013
- Author(s)
  渡邊丈久、佐々木裕.
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-25860543
[Book] 第39回日本急性肝不全研究会　藤原研司先生メモリアル＜追悼文集・記録集＞2013
- Author(s)
  吉丸洋子、溝部典生、泉和寛、川崎剛、渡邊丈久、福林光太郎、立山雅邦、田中基彦
- Publisher
  アークメディア, 東京
- Data Source
  KAKENHI-PROJECT-25860543
[Journal Article] Serum Angiopoietin-2 Levels Predict the Development of Hepatocellular Carcinoma following Hepatitis C Virus Eradication Using Direct-Acting Antiviral Agents2024
- Author(s)
  Suzuki Takanori、Matsuura Kentaro、Nagura Yoshihito、Kawamura Hayato、Fujiwara Kei、Ogawa Shintaro、Nagaoka Katsuya、Iio Etsuko、Watanabe Takehisa、Kataoka Hiromi、Tanaka Yasuhito
- Journal Title
  
  Oncology
  
  Volume: - Issue: 7 Pages: 1-10
- DOI
  10.1159/000536154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15971, KAKENHI-PROJECT-20K08314, KAKENHI-PROJECT-21K07904, KAKENHI-PROJECT-23K27589
[Journal Article] A novel, small anti-HBV compound reduces HBsAg and HBV-DNA by destabilizing HBV-RNA2024
- Author(s)
  Watanabe Takehisa、Hayashi Sanae、Zhaoyu Yan、Inada Hiroki、Nagaoka Katsuya、Tateyama Masakuni、Tanaka Yasuhito
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 59 Issue: 4 Pages: 315-328
- DOI
  10.1007/s00535-023-02070-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15971, KAKENHI-PROJECT-22K16023, KAKENHI-PROJECT-23K07442, KAKENHI-PROJECT-21K07904
[Journal Article] Hepatitis B core-related antigen: a novel and promising surrogate biomarker to guide anti-HBV therapy.2023
- Author(s)
  Inoue T, Watanabe T, Tanaka Y.
- Journal Title
  
  Clin Mol Hepatol
  
  Volume: - Issue: 4 Pages: 851-868
- DOI
  10.3350/cmh.2022.0434
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07904, KAKENHI-PROJECT-23K27589
[Journal Article] MEFV mutation is possibly associated with intestinal phenotype of Bechet disease2023
- Author(s)
  FurutaY, Gushima R, Naoe H, Fujimoto N, Honda M, Hirata S, Miyagawa E, Sakatan K, Mizuhashi Y, Iwakura M, Murai Y, Matsuoka M, Komohara Y, Tanaka Y
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 12 Issue: 9 Pages: 3131-3131
- DOI
  10.3390/jcm12093131
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08009, KAKENHI-PROJECT-20K16961, KAKENHI-PROJECT-22K15971, KAKENHI-PROJECT-22K08546
[Journal Article] Therapeutic Modifications without Discontinuation of Atezolizumab Plus Bevacizumab Therapy Are Associated with Favorable Overall Survival and Time to Progression in Patients with Unresectable Hepatocellular Carcinoma2023
- Author(s)
  Tokunaga Takayuki、Tateyama Masakuni、Kondo Yasuteru、Miuma Satoshi、Miyase Shiho、Tanaka Kentaro、Narahara Satoshi、Inada Hiroki、Kurano Sotaro、Yoshimaru Yoko、Nagaoka Katsuya、Watanabe Takehisa、Setoyama Hiroko、Fukubayashi Kotaro、Tanaka Motohiko、Tanaka Yasuhito
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 5 Pages: 1568-1568
- DOI
  10.3390/cancers15051568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15953, KAKENHI-PROJECT-21K07904
[Journal Article] Serum inducible protein 10?kDa/C‐X‐C motif chemokine?10 levels predict regression of M2BPGi‐based liver fibrosis after hepatitis?C virus eradication by direct‐acting antiviral agents2023
- Author(s)
  Nagura Yoshihito、Suzuki Takanori、Matsuura Kentaro、Ogawa Shintaro、Kawamura Hayato、Kuno Kayoko、Fujiwara Kei、Nojiri Shunsuke、Nagaoka Katsuya、Iio Etsuko、Watanabe Takehisa、Kataoka Hiromi、Tanaka Yasuhito
- Journal Title
  
  Hepatology Research
  
  Volume: 54 Issue: 1 Pages: 32-42
- DOI
  10.1111/hepr.13962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15971, KAKENHI-PROJECT-19K08427, KAKENHI-PROJECT-20K08314, KAKENHI-PROJECT-21K07904, KAKENHI-PROJECT-23K27589
[Journal Article] Clinical usefulness of inside stents in anastomotic biliary strictures after liver transplantation2023
- Author(s)
  Kugiyama Naotaka、Hashigo Shunpei、Nagaoka Katsuya、Watanabe Takehisa、Ushijima Shinya、Uramoto Yukiko、Yoshinari Motohiro、Morinaga Jun、Gushima Ryosuke、Tateyama Masakuni、Tanaka Motohiko、Naoe Hideaki、Sugawara Yasuhiko、Hibi Taizo、Tanaka Yasuhito
- Journal Title
  
  DEN Open
  
  Volume: 4 Issue: 1
- DOI
  10.1002/deo2.305
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15971, KAKENHI-PROJECT-21K07904, KAKENHI-PROJECT-21K08009
[Journal Article] Randomized phase I/II study of vascular endothelial growth factor receptor peptide vaccines for patients with hepatocellular carcinoma2023
- Author(s)
  Yoshimaru Yoko、Nagaoka Katsuya、Tanaka Kentaro、Narahara Satoshi、Inada Hiroki、Kurano Sotaro、Tokunaga Takayuki、Iio Etsuko、Watanabe Takehisa、Setoyama Hiroko、Tateyama Masakuni、Yoshida Koji、Tsunoda Takuya、Nakamura Yusuke、Tanaka Motohiko、Sasaki Yutaka、Tanaka Yasuhito
- Journal Title
  
  Hepatology Research
  
  Volume: - Issue: 5 Pages: 451-464
- DOI
  10.1111/hepr.13995
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15971, KAKENHI-PROJECT-22K16023, KAKENHI-PROJECT-23K15076, KAKENHI-PROJECT-21K07904, KAKENHI-PROJECT-21K15953, KAKENHI-PROJECT-23K27589
[Journal Article] Droplet digital PCR assay provides intrahepatic HBV?cccDNA quantification tool for clinical application2022
- Author(s)
  Hayashi Sanae、Isogawa Masanori、Kawashima Keigo、Ito Kyoko、Chuaypen Natthaya、Morine Yuji、Shimada Mitsuo、Higashi-Kuwata Nobuyo、Watanabe Takehisa、Tangkijvanich Pisit、Mitsuya Hiroaki、Tanaka Yasuhito
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1
- DOI
  10.1038/s41598-022-05882-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08313, KAKENHI-PROJECT-21K07904, KAKENHI-PROJECT-20K16996
[Journal Article] Optimal management of lenvatinib therapy for patients with unresectable hepatocellular carcinoma by balancing the therapeutic effect with the relative dose intensity.2022
- Author(s)
  Tokunaga T, Nagaoka K, Watanabe T, Tanaka M, Tanaka Y, et al.
- Journal Title
  
  Hepatol Res
  
  Volume: 52 Issue: 1 Pages: 105-119
- DOI
  10.1111/hepr.13720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07904, KAKENHI-PROJECT-21K15953
[Journal Article] Murine neonatal ketogenesis preserves mitochondrial energetics by preventing protein hyperacetylation2021
- Author(s)
  Arima Yuichiro、Nakagawa Yoshiko、Takeo Toru、Ishida Toshifumi、Yamada Toshihiro、et al.
- Journal Title
  
  Nature Metabolism
  
  Volume: 3 Issue: 2 Pages: 196-210
- DOI
  10.1038/s42255-021-00342-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08110, KAKENHI-PROJECT-19K08520, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-20H04108, KAKENHI-PROJECT-18K06817, KAKENHI-PROJECT-19K22639, KAKENHI-PROJECT-19K16111, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19K09008, KAKENHI-PROJECT-19K17403, KAKENHI-PROJECT-19H04446, KAKENHI-PROJECT-21H02686, KAKENHI-PROJECT-21K07904, KAKENHI-PROJECT-21K19519, KAKENHI-PROJECT-20KK0185, KAKENHI-PROJECT-18H02798, KAKENHI-PROJECT-19H01048
[Journal Article] Modified albumin?bilirubin grade to predict eligibility for second-line therapies at progression on sorafenib therapy in hepatocellular carcinoma patients2021
- Author(s)
  Tokunaga Takayuki、Tanaka Motohiko、Tanaka Kentaro、Narahara Satoshi、Kawasaki Takeshi、Yoshimaru Yoko、Nagaoka Katsuya、Watanabe Takehisa、Tateyama Masakuni、Naoe Hideaki、Sasaki Yutaka、Tanaka Yasuhito
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 26 Issue: 5 Pages: 922-932
- DOI
  10.1007/s10147-020-01835-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17403, KAKENHI-PROJECT-18K07945, KAKENHI-PROJECT-21K07904, KAKENHI-PROJECT-18H02798
[Journal Article] Clusterin and Related Scoring Index as Potential Early Predictors of Response to Sorafenib in Hepatocellular Carcinoma2021
- Author(s)
  Narahara S, Watanabe T, Nagaoka K, Fujimoto N, Furuta Y, Tanaka K, Tokunaga T, Kawasaki T, Yoshimaru Y, Setoyama H, Oniki K, Saruwatari J, Tateyama M, Naoe H, Tanaka M, Tanaka Y, Sasaki Y.
- Journal Title
  
  Hepatology Communications
  
  Volume: - Issue: 5 Pages: 1198-1212
- DOI
  10.1002/hep4.1872
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07166, KAKENHI-PROJECT-19K17403, KAKENHI-PROJECT-20K07134, KAKENHI-PROJECT-21K07904, KAKENHI-PROJECT-21K15953
[Journal Article] Loss of skeletal muscle mass affects the incidence of minimal hepatic encephalopathy: a case control study2020
- Author(s)
  Tateyama Masakuni、Naoe Hideaki、Tanaka Motohiko、Tanaka Kentaro、Narahara Satoshi、Tokunaga Takayuki、Kawasaki Takeshi、Yoshimaru Yoko、Nagaoka Katsuya、Watanabe Takehisa、Setoyama Hiroko、Sasaki Yutaka、Tanaka Yasuhito
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 20 Issue: 1 Pages: 371-371
- DOI
  10.1186/s12876-020-01501-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17403, KAKENHI-PROJECT-18H02798
[Journal Article] Prostaglandin E2-EP4 axis promotes lipolysis and fibrosis in adipose tissue leading to ectopic fat deposition and insulin resistance.2020
- Author(s)
  Inazumi T, Yamada K, Shirata N, Sato H, Taketomi Y, Morita K, Hohjoh H, Tsuchiya S, Oniki K, Watanabe T, Sasaki Y, Oike Y, Ogata Y, Saruwatari J, Murakami M, Sugimoto Y.
- Journal Title
  
  Cell Rep.
  
  Volume: 33 Issue: 2 Pages: 108265-108265
- DOI
  10.1016/j.celrep.2020.108265
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07166, KAKENHI-PROJECT-20K07134, KAKENHI-PROJECT-19K22503, KAKENHI-PROJECT-20K16507, KAKENHI-PUBLICLY-20H04939, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-18K06128, KAKENHI-PROJECT-18K06624, KAKENHI-PROJECT-19K22483, KAKENHI-PROJECT-18K14904, KAKENHI-PROJECT-20H05691, KAKENHI-PROJECT-18H02798
[Journal Article] Development of Kupffer cell targeting type-I interferon for the treatment of hepatitis via inducing anti-inflammatory and immunomodulatory actions.2018
- Author(s)
  4.Minayoshi Y, Maeda H, Yanagisawa H, Hamasaki K, Mizuta Y, Nishida K, Kinoshita R, Enoki Y, Imafuku T, Chuang VTG, Koga T, Fujiwara Y, Takeya M, Sonoda K, Wakayama T, Taguchi K, Ishima Y, Ishida T, Iwakiri Y, Tanaka M, Sasaki Y, Watanabe H, Otagiri M, Maruyama T.
- Journal Title
  
  Drug delivery
  
  Volume: 25 Pages: 1067-1077
- NAID
  120006941111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07945
[Journal Article] Modeling of the Weight Status and Risk of Nonalcoholic Fatty Liver Disease in Elderly Individuals: The Potential Impact of the Disulfide Bond-Forming Oxidoreductase A-Like Protein (DsbA-L) Polymorphism on the Weight Status.2018
- Author(s)
  Oniki K, Watanabe T, Kudo M, Izuka T, Ono T, Matsuda K, Sakamoto Y, Nagaoka K, Imafuku T, Ishima Y, Watanabe H, Maruyama T, Otake K, Ogata Y, Saruwatari J.
- Journal Title
  
  CPT:Pharmacometrics & Systems Pharmacology
  
  Volume: - Issue: 6 Pages: 384-393
- DOI
  10.1002/psp4.12292
- NAID
  120006937616
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08406, KAKENHI-PROJECT-17K15510, KAKENHI-PROJECT-26350872, KAKENHI-PROJECT-17J11624, KAKENHI-PROJECT-18K15820
[Journal Article] 3.Modeling of the Weight Status and Risk of Nonalcoholic Fatty Liver Disease in Elderly Individuals: The Potential Impact of the Disulfide Bond-Forming Oxidoreductase A-Like Protein (DsbA-L) Polymorphism on the Weight Status.2018
- Author(s)
  Oniki K, Watanabe T, Kudo M, Izuka T, Ono T, Matsuda K, Sakamoto Y, Nagaoka K, Imafuku T, Ishima Y, Watanabe H, Maruyama T, Otake K, Ogata Y, Saruwatari J.
- Journal Title
  
  CPT Pharmacometrics Syst Pharmacol
  
  Volume: 7 Pages: 384-393
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07945
[Journal Article] Genetic Fusion of Type-I Interferon to a Recombinant Albumin Mutant with polymannosylated N-linked oligosaccharide attached is a Novel and Superior Kupffer Cell Targeting Agent for the Treatment of Hepatitis.2018
- Author(s)
  Minayoshi Y, Maeda H, Yanagisawa H, Hamasaki K, Mizuta Y, Nishida K, Kinoshita R, Enoki Y, Imafuku T, Chuang VTG, Koga T, Fujiwara Y, Takeya M, Sonoda K, Wakayama T, Taguchi K, Ishima Y, Ishida T, Iwakiri Y, Tanaka M, Sasaki Y, Watanabe H, Otagiri M, Maruyama T.
- Journal Title
  
  Drug Delivery
  
  Volume: 25 Issue: 1 Pages: 1067-1077
- DOI
  10.1080/10717544.2018.1464083
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08664, KAKENHI-PROJECT-17K15511, KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-16K09247, KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-18H02798
[Journal Article] Outcomes of treatment with daclatasvir and asunaprevir for recurrent hepatitis C after liver transplantation2017
- Author(s)
  Honda M, Sugawara Y, Watanabe T, Tateyama M, Tanaka M, Uchida K, Kawabata S, Yoshii D, Miura K, Isono K, Hayashida S, Ohya Y, Yamamoto H, Sasaki Y, Inomata Y
- Journal Title
  
  Hepatology Research
  
  Volume: - Issue: 11 Pages: 1147-1154
- DOI
  10.1111/hepr.12853
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293173, KAKENHI-PROJECT-16K11349
[Journal Article] The glucocorticoid receptor regulates the ANGPTL4 gene in a CTCF-mediated chromatin context in human hepatic cells2017
- Author(s)
  Nakamoto M, Ishihara K, Watanabe T, Hirosue A, Hino S, Shinohara M, Nakayama H, Nakao M
- Journal Title
  
  PLoS One
  
  Volume: 12
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293173
[Journal Article] Oral branched-chain amino acid granules improve structure and function of human serum albumin in liver cirrhotic patients2017
- Author(s)
  Setoyama　H, Tanaka M, Nagumo K, Naoe H, Watanabe T, Yoshimaru Y, Tateyama M, Sasaki M, Watanabe H, Otagiri M, Maruyama T and Sasaki Y
- Journal Title
  
  J Gastroenterol
  
  Volume: - Issue: 6 Pages: 754-765
- DOI
  10.1007/s00535-016-1281-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293173, KAKENHI-PROJECT-15K15008
[Journal Article] The longitudinal effect of the aldehyde dehydrogenase 2 *2 allele on the risk for non-alcoholic fatty liver disease2016
- Author(s)
  Oniki K, Morita K, Watanabe T, Kajiwara A, Otake K, Nakagawa K, Sasaki Y, OgataY and Saruwatari J
- Journal Title
  
  Nutrition & Diabetes
  
  Volume: 6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293173
[Journal Article] The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome2016
- Author(s)
  Satou Y, Miyazato P, Ishihara K, Yaguchi H, Melamed A, Miura M, Fukuda A, Nosaka K, Watanabe T, Rowan AG, Nakao M, Bangham CR
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 11 Pages: 3054-3059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293173
[Journal Article] The retrovirus HTLV-1 inserts an ectopic CTCF-binding site into the human genome.2016
- Author(s)
  Satou Y, Miyazato P, Ishihara K, Yaguchi H, Melamed A, Miura M, Fukuda A, Nosaka K, Watanabe T, Rowan AG, Nakao M, Bangham CR.
- Journal Title
  
  The Proceedings of the National Academy of Sciences
  
  Volume: 11 Pages: 3054-3059
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860543
[Journal Article] Ledipasvir and sofosbuvir for recurrent hepatitis C after liver transplantation2016
- Author(s)
  Oya Y, Sugawara Y, Watanabe T, Yoshimaru Y, Honda M, Hashimoto S, Yoshii D, Isono K, Hayashida S, Yamamoto H, Tanaka M, Sasaki Y, Inomata Y
- Journal Title
  
  Bioscience Trends
  
  Volume: 10 Pages: 496-499
- NAID
  130005295919
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293173
[Journal Article] Incidence and risk factors of synchronous colorectal cancer in patients with esophageal cancer: an analysis of 480 consecutive colonoscopies before surgery2016
- Author(s)
  Yoshida N, Tamaoki Y, Baba Y, Sakamoto Y, Miyamoto Y, Iwatsuki M, Shono T, Miyamoto H, Imuta M, Kurashige J, Sawayama H, Tokunaga R, Watanabe M, Sasaki Y, Yamashita Y, Baba H.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 6 Issue: 6 Pages: 1079-1084
- DOI
  10.1007/s10147-016-1015-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460974, KAKENHI-PROJECT-16K19942, KAKENHI-PROJECT-16K19943
[Journal Article] Carbohydrate antigen 19-9 is a useful prognostic marker in esophagogastric junction adenocarcinoma.2015
- Author(s)
  Tokunaga R, Imamura Y, Nakamura K, Uchihara T, Ishimoto T, Nakagawa S, Iwatsuki M, Baba Y, Sakamoto Y, Miyamoto Y, Yoshida N, Oyama S, Shono T, Naoe H, Saeki H, Oki E,Watanabe M, Sasaki Y, Maehara Y, Baba H
- Journal Title
  
  Cancer Med
  
  Volume: 11 Issue: 11 Pages: 1659-66
- DOI
  10.1002/cam4.514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293173
[Journal Article] Evaluation of sorafenib treatment and hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma: a comparative study using the propensity score matching method.2015
- Author(s)
  Fukubayashi K, Tanaka M, Izumi K, Watanabe T, Fujie S, Kawasaki T, Yoshimaru Y, Tateyama M, Setoyama H, Naoe H, Kikuchi K, Sasaki Y.
- Journal Title
  
  Cancer Medicine
  
  Volume: 8 Pages: 1214-1223
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25860543
[Journal Article] Polythiol-containing, recombinant mannosylated-albumin is a superior CD68+/CD206+ Kupffer cell-targeted nano-antioxidant for the treatment of two acute hepatitis models.2015
- Author(s)
  Maeda H, Hirata K, Watanabe H, Ishima Y, Chuang VT, Taguchi K, Inatsu A, Kinoshita M, Tanaka M, Sasaki Y, Otagiri M, Maruyama T.
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 352 Issue: 2 Pages: 244-257
- DOI
  10.1124/jpet.114.219493
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390043, KAKENHI-PROJECT-25460190, KAKENHI-PROJECT-25670085, KAKENHI-PROJECT-15K08076, KAKENHI-PROJECT-26670569, KAKENHI-PROJECT-25293173, KAKENHI-PROJECT-25293369
[Journal Article] Evaluation　of　sorafenib　treatment　and　hepatic　arterial　infusion　chemotherapy　for advanced　hepatocellular carcinoma: a comparative study using the propensity score matching method.2015
- Author(s)
  Fukubayashi K, Tanaka M, Izumi K, Watanabe T, Fujie S, Kawasaki T, Yoshimaru Y, Tateyama M, Setoyama H, Naoe H, Kikuchi K and Sasaki Y
- Journal Title
  
  Cancer Med.
  
  Volume: 8 Issue: 8 Pages: 1214-23
- DOI
  10.1002/cam4.476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293173
[Journal Article] 脳死肝移植登録中にB型急性肝炎を発症した原発性胆汁性肝硬変の1例.2014
- Author(s)
  平江麻衣、渡邊丈久、吉丸洋子、川崎剛、泉和寛、溝部典生、福林光太郎、立山雅邦、田中基彦、猪山賢一、佐々木裕.
- Journal Title
  
  肝臓
  
  Volume: 55 Pages: 176-781
- NAID
  130003393972
- Data Source
  KAKENHI-PROJECT-25293173
[Journal Article] NF-κBシグナル研究のこれまでの変遷. 特集／肝胆膵領域におけるNF-κB研究の最前線.2014
- Author(s)
  渡邊丈久、佐々木裕.
- Journal Title
  
  肝胆膵
  
  Volume: 68 Pages: 495-503
- Data Source
  KAKENHI-PROJECT-25860543
[Journal Article] NF-κBシグナル研究のこれまでの変遷2014
- Author(s)
  渡邊丈久、佐々木裕
- Journal Title
  
  特集／肝胆膵領域におけるNF-κB研究の最前線肝胆膵
  
  Volume: 68 Pages: 495-503
- Data Source
  KAKENHI-PROJECT-25860543
[Journal Article] 脳死肝移植登録中にB型急性肝炎を発症した原発性胆汁性肝硬変の1例.2014
- Author(s)
  平江麻衣、渡邊丈久、吉丸洋子、川崎剛、泉和寛、溝部典生、福林光太郎、立山雅邦、田中基彦、猪山賢一、佐々木裕.
- Journal Title
  
  肝臓
  
  Volume: 55 Pages: 176-781
- NAID
  130003393972
- Data Source
  KAKENHI-PROJECT-25860543
[Journal Article] Cys34-cysteinylated human serum albumin is a sensitive plasma marker in oxidative stress-related chronic disease.2014
- Author(s)
  Nagumo K, Tanaka M, Chuang V, Setoyama H, Watanabe H, Yamada N, Kubota K, Tanaka M, Matsushita K, Yoshida A, Jinnouchi H, Anraku M, Kadowaki D, Ishima Y, Sasaki Y, Otagiri M, Maruyama T.
- Journal Title
  
  PLOS ONE　9(1) e85216
  
  Volume: in press
- Data Source
  KAKENHI-PROJECT-25293173
[Journal Article] 脳死肝移植登録中にB 型急性1 肝炎を発症した原発性胆汁性肝硬変の1例2014
- Author(s)
  平江麻衣、渡邊丈久、吉丸洋子、川崎剛、泉和寛、溝部典生、福林光太郎、立山雅邦、田中基彦、猪山賢一、佐々木裕
- Journal Title
  
  肝臓
  
  Volume: 55 Pages: 176-781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860543
[Journal Article] NF-κBシグナル研究のこれまでの変遷. 特集／肝胆膵領域におけるNF-κB研究の最前線.2014
- Author(s)
  渡邊丈久、佐々木裕.
- Journal Title
  
  肝胆膵
  
  Volume: 68 Pages: 495-503
- Data Source
  KAKENHI-PROJECT-25293173
[Journal Article] C型肝炎深慮における肝臓専門医の役割2014
- Author(s)
  立山雅邦、渡邊丈久、福林光太郎、田中基彦、佐々木裕.
- Journal Title
  
  臨床消化器内科
  
  Volume: 6月増刊号 29 Pages: 88-91
- Data Source
  KAKENHI-PROJECT-25293173
[Journal Article] Cys34-cysteinylated human serum albumin is a sensitive plasma marker in oxidative stress-related chronic disease.2014
- Author(s)
  Nagumo K, Tanaka M, Chuang V, Setoyama H, Watanabe H, Yamada N, Kubota K, Tanaka M, Matsushita K, Yoshida A, Jinnouchi H, Anraku M, Kadowaki D, Ishima Y, Sasaki Y, Otagiri M, Maruyama T.
- Journal Title
  
  PLOS ONE
  
  Volume: 9(1)
- Data Source
  KAKENHI-PROJECT-25293173
[Journal Article] 肝癌治療後の化学療法による再発予防.2013
- Author(s)
  田中基彦、渡邊丈久、福林光太郎、立山雅邦、佐々木裕.
- Journal Title
  
  The Liver Cancer Journal
  
  Volume: 5 Pages: 100-109
- Data Source
  KAKENHI-PROJECT-25860543
[Journal Article] 定義と概念2013
- Author(s)
  渡邊丈久、田中基彦、佐々木裕
- Journal Title
  
  最新医学別冊　新しい診断と治療のABC 肝硬変　改訂第2版, 最新医学社
  
  Volume: 44 Pages: 13-19
- Data Source
  KAKENHI-PROJECT-25860543
[Journal Article] Pancreatic metastasis from mixed adenoneuroendocrine carcinoma of the uterine cervix: a case report.2013
- Author(s)
  Nishimura C, Naoe H, Hashigo S, Tsutsumi H, Ishii S, Konoe T, Watanabe T, Shono T, Sakurai K, Takaishi K, Ikuta Y, Chikamoto A, Tanaka M, Iyama K, Baba H, Katabuchi H, and Sasaki Y.
- Journal Title
  
  Case Reports in Oncology
  
  Volume: 6 Pages: 256-262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860543
[Journal Article] Higher-order chromatin regulation and differential gene expression in human Tumor necrosis factor / Lymphotoxin locus in hepatocellular carcinoma cells.2012
- Author(s)
  Watanabe T, Ishihara K, Hirosue A, Watanabe S, Hino S, Ojima H, Kanai Y, Sasaki Y and Nakao M.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 32 Pages: 1529-1541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390230
[Journal Article] Peretinoin　非環式レチノイドによる肝細胞癌再発抑止2012
- Author(s)
  泉和寛、渡邊丈久、立山雅邦、田中基彦、佐々木裕
- Journal Title
  
  肝・胆・膵
  
  Volume: 65 Pages: 1334-1338
- Data Source
  KAKENHI-PROJECT-21390230
[Journal Article] 肝癌予防の基礎と臨床2012
- Author(s)
  渡邊丈久、田中基彦、佐々木裕
- Journal Title
  
  Medicina
  
  Volume: 49 Pages: 1230-1232
- Data Source
  KAKENHI-PROJECT-21390230
[Journal Article] Higher-Order Chromatin Regulation and Differential Gene Expression in the Human Tumor Necrosis Factor/Lymphotoxin Locus in Hepatocellular Carcinoma Cells2012
- Author(s)
  Watanabe T, Ishihara Ko, Hirosue A, Watanabe S, Hino S, Ojima H, Kanai Y, Sasaki Y, Nakao M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 32 Pages: 1529-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390230
[Journal Article] Higher-order chromatin regulation anddifferential gene expression in human TNF/L Tlocus in hapatocellular carcinoma cells2012
- Author(s)
  Watanabe T, Sasaki Y, Nakao M, et al. (他 6名)
- Journal Title
  
  Mol. Cell. Biol
  
  Volume: 32 Pages: 1529-1541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390230
[Journal Article] Efficacy and safety of eltrombopag in Japanese patients with chronic liver disease and thrombocytopenia: a randomized, open-label, phase II study.2012
- Author(s)
  Kawaguchi T, Komori A, Seike M, Fujiyama S, Watanabe H, Tanaka M, Sakisaka S, Nakamuta M, Sasaki Y, Oketani M, Hattori T, Katsura K and Sata M.
- Journal Title
  
  J Gastroenterol
  
  Volume: 47 Pages: 1342-1351
- NAID
  10031145521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390230
[Journal Article] The incidence of hepatocellular carcinoma associated with hepatitis C infection decreased in Kyushu area2011
- Author(s)
  Taura N, Fukushima N, Yatsuhashi H, Takami Y, Seike M, Watanabe H, Mizuta T, Sasaki Y,Nagata K, Tabara A, Komorizono Y, Taketomi A, Matsumoto S, Tamai T, Muro T, Nakao K, Fukuizumi K, Maeshiro T, Inoue O, Sata M
- Journal Title
  
  Med Sci Monit
  
  Volume: 17 Pages: 7-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390230
[Presentation] A Possible diagnostic marker of mitochondrial dysfunction, AREG, is associated with tumor size in hepatocellular carcinoma.2023
- Author(s)
  Nagaoka K, Watanabe T, Tanaka Y, et al.
- Organizer
  APASL Single Topic Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07904
[Presentation] ミトコンドリア機能不全がもたらすNAFLD肝組織におけるアンフィレグリン発現増加2023
- Author(s)
  長岡克弥、渡邊丈久、田中靖人
- Organizer
  第109回日本消化器病学会総会　シンポジウム13
- Data Source
  KAKENHI-PROJECT-21K07904
[Presentation] INTERFERON-RELATED GENE EXPRESSION CHANGES MEDIATED BY ALPHAFETOPROTEIN IN PATIENTS WHO DEVELOPED HEPATOCELLULAR CARCINOMA AFTER HEPATITIS C VIRUS ERADICATION2023
- Author(s)
  Nagaoka K, Watanabe T, Tanaka Y, et al.
- Organizer
  American Association for the Study of Liver Disease, Liver meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07904
[Presentation] 転写因子・エピゲノム統合解析を用いた肝細胞癌ミトコンドリア機能不全の診断マーカーの同定2023
- Author(s)
  長岡克弥、渡邊丈久、田中靖人
- Organizer
  第59回日本肝臓学会総会パネルディスカッション4
- Data Source
  KAKENHI-PROJECT-21K07904
[Presentation] Novel serum biomarkers useful for drug selection of sorafenib and lenvatinib for hepatocellular carcinoma2021
- Author(s)
  Narahara S, Watanabe T, Tanaka Y, et al.,
- Organizer
  The 72nd Annual Meeting of the American Association for the Study of Liver Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07904
[Presentation] ヒストン修飾酵素LSD2による肝脂質代謝制御と栄養環境対応性の発現変化～NAFLDの病態解明を目指して～2021
- Author(s)
  長岡克弥、渡邊丈久、楢原哲史、田中健太郎、徳永尭之、川崎剛、吉丸洋子、瀬戸山博子、立山雅邦、田中基彦、佐々木裕、田中靖人
- Organizer
  第25回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-21K07904
[Presentation] 肝細胞癌に対するソラフェニブ・レンバチニブの薬剤選択に有用な血清バイオマーカーの解析2021
- Author(s)
  楢原哲史、渡邊丈久、田中靖人
- Organizer
  第57回日本肝臓学会
- Data Source
  KAKENHI-PROJECT-21K07904
[Presentation] 翻訳後修飾の網羅的解析による肝癌の治療抵抗性の解明2020
- Author(s)
  直江秀昭、渡邊丈久、田中基彦
- Organizer
  第56回日本肝臓学会総会　シンポジウム
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] Prognostic factors associated with survival in hepatocellular carcinoma patients progressed on lenvatinib therapy, premising subsequent chemotherapy2020
- Author(s)
  Tokunaga T, Nagaoka K, Watanabe T, Tanaka Y, et al.
- Organizer
  Liver Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD)
- Data Source
  KAKENHI-PROJECT-18H02798
[Presentation] A novel serum biomarker, Clusterin, and related predictive index scoring could be an early predictor of response to Sorafenib in patients with advanced hepatocellular carcinoma2020
- Author(s)
  Narahara S, Watanabe T, Nagaoka K, Naoe H, Sasaki Y, Tanaka Y, et al.
- Organizer
  Liver Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD)
- Data Source
  KAKENHI-PROJECT-18H02798
[Presentation] 当院におけるHBV電子カルテスクリーニングシステム導入の有用性の評価2020
- Author(s)
  渡邊丈久、楢原哲史、田中健太郎、徳永尭之、川崎剛、吉丸洋子、長岡克弥、瀬戸山博子、立山雅邦、田中基彦
- Organizer
  第24回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-18H02798
[Presentation] DAAs治療後の血清Exosome中miRNAの変化はSVR後の生体反応を反映する2020
- Author(s)
  渡邊丈久
- Organizer
  第56回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18H02798
[Presentation] DAAs治療後の血清Exosome中miRNAの変化はSVR後の生体反応を反映する2020
- Author(s)
  渡邊丈久、田中基彦
- Organizer
  第56回日本肝臓学会総会　ワークショップ
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] 肝細胞癌に対するソラフェニブの治療効果を早期に予測する血清バイオマーカーの解析2020
- Author(s)
  楢原哲史、渡邊丈久、田中基彦
- Organizer
  第56回日本肝臓学会総会　ワークショップ
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] 翻訳後修飾の網羅的解析による肝癌の治療抵抗性の解明2020
- Author(s)
  直江秀昭、渡邊丈久、田中基彦
- Organizer
  第56回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18H02798
[Presentation] 肝細胞癌に対する肝動脈化学塞栓術から分子標的治療への適切な切り替えタイミングの検討2019
- Author(s)
  徳永尭之、田中健太郎、楢原哲史、吉丸洋子、川崎剛、長岡克弥、渡邊丈久、立山雅邦、田中基彦、佐々木裕
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18H02798
[Presentation] MULTI-OMICS ANALYSES IDENTIFY NUCLEOPHOSMIN AS A KEY REGULATOR OF APOPTOSIS RESISTANCE IN HUMAN HEPATOCELLULAR CARCINOMA2019
- Author(s)
  Hideaki Naoe, Takehisa Watanabe, Katsuya Nagaoka, Nahoko Fujimoto, Norie Araki, Jiro Fujimoto, Motohiko Tanaka and Yutaka Sasaki
- Organizer
  The Liver Meeting 2019 - AASLD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02798
[Presentation] 肝癌分子標的治療薬の治療効果予測と耐性獲得機序の解析2019
- Author(s)
  長岡克弥、楢原哲史、渡邊丈久、田中基彦、佐々木裕
- Organizer
  第26回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] 切除不能進行肝細胞癌に対するソラフェニブを基軸とした集学的治療戦略2019
- Author(s)
  徳永尭之、田中健太郎、楢原哲史、長岡克弥、吉丸洋子、渡邊丈久、立山雅邦、田中基彦、佐々木裕
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18H02798
[Presentation] 肝細胞癌に対するソラフェニブの治療効果を早期に予測する新規血清バイオマーカーの解析2019
- Author(s)
  楢原哲史、渡邊丈久、長岡克弥、田中健太郎、徳永尭之、川崎剛、吉丸洋子、瀬戸山博子、立山雅邦、直江秀昭、田中基彦、佐々木裕
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18H02798
[Presentation] 進行肝細胞癌に対する集学的なソラフェニブ治療戦略2019
- Author(s)
  徳永尭之、田中健太郎、楢原哲史、吉丸洋子、川崎剛、長岡克弥、渡邊丈久、立山雅邦、田中基彦、佐々木裕
- Organizer
  第27回日本消化器関連学会週間
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] Optimal strategy of switching from transarterial chemoembolization to molecular targeted therapy for patients with unresectable hepatocellular carcinoma.2019
- Author(s)
  Takayuki Tokunaga, Motohiko Tanaka, Kentaro Tanaka, Satoshi Narahara, Yoko Yoshimaru, Tekeshi Kawasaki, Katsuya Nagaoka, Takehisa Watanabe, Masakuni Tateyama, Yutaka Sasaki
- Organizer
  The Liver Meeting (AASLD) 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] Altered microRNA expression profiles in serum exosome links to clinical phenotypes induced by direct-acting antiviral therapy.2019
- Author(s)
  Takehisa Watanabe, Nahoko Fujimoto, Katsuya Nagaoka, Satoshi Narahara, Kentaro Tanaka, Takayuki Tokunaga, Takeshi Kawasaki, Yoko Yoshimaru, Masakuni Tateyama, Hideaki Naoe, Motohiko Tanaka, and Yutaka Sasaki.
- Organizer
  THE LIVER MEETING　AASLD 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15820
[Presentation] 肝内腫瘍量の多い切除不能進行肝細胞癌に対するlenvatinibの使用経験2019
- Author(s)
  田中健太郎、楢原哲史、徳永尭之、川崎剛、長岡克弥、吉丸洋子、渡邊丈久、立山雅邦、田中基彦、佐々木裕
- Organizer
  第20回日本肝がん分子標的治療研究会
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] UPREGULATION OF SECRETORY CLUSTERIN IN RESPONSE TO SORAFENIB LINKS TO ACQUIRED TREATMENT RESISTANCE OF HEPATOCELLULAR CARCINOMA.2019
- Author(s)
  Satoshi Narahara, Takehisa Watanabe, Katsuya Nagaoka, Nahoko Fujimoto, Kentaro Tanaka, Takeshi Kawasaki, Yoko Yoshimaru, Masakuni Tateyama, Hideaki Naoe, Motohiko Tanaka and Yutaka Sasaki
- Organizer
  The Liver Meeting 2019 - AASLD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02798
[Presentation] Upregulation of secretory clusterin in response to sorafenib links to acquired treatment resistance of hepatocellular carcinoma.2019
- Author(s)
  Satoshi Narahara, Takehisa Watanabe, Katsuya Nagaoka, Nahoko Fujimoto, Kentaro Tanaka, Takeshi Kawasaki, Yoko Yoshimaru, Masakuni Tateyama, Hideaki Naoe, Motohiko Tanaka, Yutaka Sasaki
- Organizer
  The Liver Meeting (AASLD) 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] 進行肝細胞癌に対する集学的なソラフェニブ治療戦略2019
- Author(s)
  28.徳永尭之、田中基彦、田中健太郎、楢原哲史、吉丸洋子、川崎剛、長岡克弥、渡邊丈久、立山雅邦、佐々木裕
- Organizer
  JDDW 2019（第27回　日本消化器関連学会週間）
- Data Source
  KAKENHI-PROJECT-18H02798
[Presentation] 切除不能進行肝細胞癌に対するソラフェニブを基軸とした集学的治療戦略2019
- Author(s)
  徳永尭之、田中基彦、田中健太郎、楢原哲史、吉丸洋子、川崎剛　長岡克弥　渡邊丈久　立山雅邦　佐々木裕
- Organizer
  第105回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] Multi-omics analyses identify nucleophosmin as a key regulator of apoptosis resistance in human hepatocellular carcinoma.2019
- Author(s)
  Hideaki Naoe, Takehisa Watanabe, Katsuya Nagaoka, Nahoko Fujimoto, Norie Araki, Jiro Fujimoto, Motohiko Tanaka, Yutaka Sasaki
- Organizer
  The Liver Meeting (AASLD) 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] OPTIMAL STRATEGY OF SWITCHING FROM TRANSARTERIAL CHEMOEMBOLIZATION TO MOLECULAR TARGETED THERAPY FOR PATIENTS WITH UNRESECTABLE HEPATOCELLULAR CARCINOMA2019
- Author(s)
  Takayuki Tokunaga, Motohiko Tanaka, Kentaro Tanaka, Satoshi Narahara, Yoko Yoshimaru, Tekeshi Kawasaki, Katsuya Nagaoka, Takehisa Watanabe, Masakuni Tateyama and Yutaka Sasaki
- Organizer
  The Liver Meeting 2019 - AASLD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02798
[Presentation] 肝細胞癌に対する肝動脈化学塞栓術から分子標的治療への適切な切り替えタイミングの検討2019
- Author(s)
  徳永尭之、田中健太郎、楢原哲史、吉丸洋子、川崎剛、長岡克弥、渡邊丈久、立山雅邦、田中基彦、佐々木裕
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] 当科における切除不能肝細胞癌に対するレンバチニブ治療の初期経験2019
- Author(s)
  田中健太郎、徳永尭之、楢原哲史、川崎剛、長岡克弥、瀬戸山博子、吉丸洋子、渡邊丈久、立山雅邦、田中基彦、佐々木裕
- Organizer
  第19回日本肝がん分子標的治療研究会
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] Altered microrna expression profiles in serum exosome links to clinical phenotypes induced by direct-acting antiviral therapy.2019
- Author(s)
  Takehisa Watanabe, Nahoko Fujimoto, Katsuya, Satoshi Narahara, Kentaro Tanaka, Takayuki Tokunaga, Takeshi Kawasaki, Yoko Yoshimaru, Masakuni Tateyama, Hideaki Naoe, Motohiko Tanaka, Yutaka Sasaki
- Organizer
  The Liver Meeting (AASLD) 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] 肝細胞癌に対するソラフェニブの治療効果を早期に予測する新規血清バイオマーカーの解析2019
- Author(s)
  楢原哲史、渡邊丈久、長岡克弥、田中健太郎、徳永尭之、川崎剛、吉丸洋子、瀬戸山博子、立山雅邦、直江秀昭、田中基彦、佐々木裕
- Organizer
  第55回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] 進行肝細胞癌に対するソラフェニブ治療の効果解析から検討する後治療を見据えた治療戦略2018
- Author(s)
  徳永尭之、田中基彦、田中健太郎、楢原哲史、川崎剛、吉丸洋子、渡邊丈久、瀬戸山博子、立山雅邦、佐々木裕
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] Treatment Strategy Based on Sorafenib for Advanced Hepatocellular Carcinoma2018
- Author(s)
  Takayuki Tokunaga,Motohiko Tanaka,Kentaro Tanaka,Satoshi Narahara,Youko Yoshimaru,Katsuya Nagaoka,Takeshi Kawasaki,Hiroko Setoyama,Takehisa Watanabe,Masakuni Tateyama and Yutaka Sasaki
- Organizer
  The Liver Meeting 2018 - AASLD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02798
[Presentation] 11.TACE不応例に対する肝動注化学療法後に進行した肝細胞癌への後治療の検討2018
- Author(s)
  田中健太郎、楢原哲史、徳永尭之、川崎剛、吉丸洋子、渡邊丈久、長岡克弥、立山雅邦、田中基彦、佐々木裕.
- Organizer
  第112回日本消化器病学会九州支部例会
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] 当科における肝細胞癌根治例における抗ウイルス療法後の再発に関する検討2018
- Author(s)
  立山雅邦、田中基彦、田中健太郎、楢原哲史、徳永尭之、川崎剛、吉丸洋子、渡邊丈久、佐々木裕.
- Organizer
  第104回日本消化器病学会総会,
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] Analysis of the Changes of the Profiles of Exosomal miRNA in Serum of the Patients Induced By DAA Treatment.2018
- Author(s)
  Takehisa Watanabe, Nahoko Fujimoto, Katsuya Nagaoka, Satoshi Narahara, Kentaro Tanaka, Takayuki Tokunaga, Takeshi Kawasaki, Youko Yoshimaru, Masakuni Tateyama, Hideaki Naoe, Motohiko Tanaka and Yutaka Sasaki.
- Organizer
  The Liver Meeting (AASLD) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15820
[Presentation] 肝細胞癌に対するソラフェニブの治療効果を早期に予測する新規血清バイオマーカーの解析2018
- Author(s)
  楢原哲史、渡邊丈久、田中健太郎、徳永尭之、川崎剛、吉丸洋子、立山雅邦、田中基彦、佐々木裕.
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K15820
[Presentation] Treatment Strategy Based on Sorafenib for Advanced Hepatocellular Carcinoma Premising Subsequent Treatment with Regorafenib.2018
- Author(s)
  Tokunaga Takayuki, Tanaka Motohiko Tanaka Kentaro, Narahara Satoshi, Yoshimaru Yoko, Nagaoka Katsuya, Kawasaki Takeshi, Setoyama Hiroko, Watanabe Takehisa, Tateyama Masakuni, Sasaki Yutaka.
- Organizer
  The Liver Meeting (AASLD) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] Prognostic Factors in Patients with Advanced HCC Receiving Sorafenib or Hepatic Arterial Infusion Chemotherapy.2018
- Author(s)
  Motohiko Tanaka, Takayuki Tokunaga, Kentaro Tanaka, Satoshi Narahara, Takeshi Kawasaki, Yoko Yoshimaru, Takehisa Watanabe, Masakuni Tateyama, Hideaki Naoe, Yutaka Sasaki.
- Organizer
  The Asian Pacific Association for the Study of the Liver
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] 進行肝細胞癌に対する肝動注化学療法の効果解析から検討する治療戦略2018
- Author(s)
  田中健太郎、徳永尭之、楢原哲史、川崎剛、吉丸洋子、渡邊丈久、瀬戸山博子、立山雅邦、田中基彦、佐々木裕
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] Early Prediction of Sorafenib Response in Patients with Hepatocellular Carcinoma: The Possible Role of Secretory Clusterin in Acquired Sorafenib Resistance.2018
- Author(s)
  Satoshi Narahara,Takehisa Watanabe,Katsuya Nagaoka,Nahoko Fujimoto,Kentaro Tanaka,Takayuki Tokunaga,Takeshi Kawasaki,Youko Yoshimaru,Hiroko Setoyama,Masakuni Tateyama,Hideaki Naoe,Motohiko Tanaka and Yutaka Sasaki
- Organizer
  The Liver Meeting 2018 - AASLD
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02798
[Presentation] Early Prediction of Sorafenib Response in Patients with Hepatocellular Carcinoma: The Possible Role of Secretory Clusterin in Acquired Sorafenib Resistance.2018
- Author(s)
  Narahara Satoshi, Watanabe Takehisa, Nagaoka Katsuya, Fujimoto Nahoko, Tanaka Kentaro, Tokunaga Takayuki, Kawasaki Takeshi, Yoshimaru Youko, Setoyama Hiroko, Tateyama Masakuni, Naoe Hideaki, Tanaka Motohiko, Sasaki Yutaka.
- Organizer
  The Liver Meeting (AASLD) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15820
[Presentation] Early Prediction of Sorafenib Response in Patients with Hepatocellular Carcinoma: The Possible Role of Secretory Clusterin in Acquired Sorafenib Resistance.2018
- Author(s)
  Narahara Satoshi, Watanabe Takehisa, Nagaoka Katsuya, Fujimoto Nahoko, Tanaka Kentaro, Tokunaga Takayuki, Kawasaki Takeshi, Yoshimaru Youko, Setoyama Hiroko, Tateyama Masakuni, Naoe Hideaki, Tanaka Motohiko, Sasaki Yutaka.
- Organizer
  The Liver Meeting (AASLD) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] 肝細胞癌に対するソラフェニブの治療効果を早期に予測する新規血清バイオマーカーの解析2018
- Author(s)
  楢原哲史、渡邊丈久、田中健太郎、徳永尭之、川崎剛、吉丸洋子、立山雅邦、田中基彦、佐々木裕
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18H02798
[Presentation] 肝細胞癌に対するソラフェニブの治療効果を早期に予測する新規血清バイオマーカーの解析2018
- Author(s)
  楢原哲史、渡邊丈久、田中健太郎、徳永尭之、川崎剛、吉丸洋子、立山雅邦、田中基彦、佐々木裕.
- Organizer
  第54回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] Prognostic Factors in Patients with Advanced HCC Receiving Sorafenib or Hepatic Arterial Infusion Chemotherapy2018
- Author(s)
  Motohiko Tanaka, Takayuki Tokunaga, Kentaro Tanaka, Satoshi Narahara, Takeshi Kawasaki, Yoko Yoshimaru, Takehisa Watanabe, Masakuni Tateyama, Hideaki Naoe, Yutaka Sasaki
- Organizer
  The Asian Pacific Association for the Study of the Liver
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02798
[Presentation] Analysis of the Changes of the Profiles of Exosomal miRNA in Serum of the Patients Induced By DAA Treatment.2018
- Author(s)
  Takehisa Watanabe, Nahoko Fujimoto, Katsuya Nagaoka, Satoshi Narahara, Kentaro Tanaka, Takayuki Tokunaga, Takeshi Kawasaki, Youko Yoshimaru, Masakuni Tateyama, Hideaki Naoe, Motohiko Tanaka and Yutaka Sasaki.
- Organizer
  The Liver Meeting (AASLD) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07945
[Presentation] 当科における肝細胞癌根治例における抗ウイルス療法後の再発に関する検討2018
- Author(s)
  立山雅邦、田中基彦、田中健太郎、楢原哲史、徳永尭之、川崎剛、吉丸洋子、渡邊丈久、佐々木裕.
- Organizer
  第104回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18K15820
[Presentation] A novel serum biomarker , clusterin , could be an early predictor of response to sorafenib2016
- Author(s)
  Takehisa Watanabe , Satoshi Narahara , Motohiko Tanaka , Yutaka Sasaki
- Organizer
  AASLD　The　Liver　Meeting
- Place of Presentation
  Boston
- Year and Date
  2016-11-11
- Data Source
  KAKENHI-PROJECT-25293173
[Presentation] Combination therapy with Daclatasvir and Asunaprevir for the patients infected with HCV genotype 12016
- Author(s)
  Masakuni Tateyama , Motohiko Tanaka, Takayuki Tokunaga, Takeshi Kawasaki, Satomi Fujie, Yoko Yoshimaru, Takehisa Watanabe, Hiroko Setoyama, Takeyasu Kounoe, Yoshinari Sakai, Masato Sasaki, Kazuhiro Sugi, Shiho Miyase, Shigetoshi Fujiyama, Yutaka Sasaki
- Organizer
  HCV2016
- Place of Presentation
  Kyoto
- Year and Date
  2016-10-11
- Data Source
  KAKENHI-PROJECT-25293173
[Presentation] エピジェネティクス因子による肝脂質代謝調節～ヒストン修飾酵素LSD2に焦点を当てたNASH・NAFLDの病態解明に向けて～2016
- Author(s)
  長岡克弥、渡邊丈久、佐々木裕
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  千葉
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-25293173
[Presentation] Clinical outcomes of hepatocellular carcinoma patients who obtained HCV eradication after interferon therapy2016
- Author(s)
  Motohiko Tanaka, Yoko Yoshimaru, Takayoshi Sonoda, Takayuki Tokunaga, Takeshi Kawasaki, Satomi Fujie, Takehisa Watanabe, Hiroko Setoyama, Masakuni Tateyama, Yutaka Sasaki
- Organizer
  HCV2016
- Place of Presentation
  Kyoto
- Year and Date
  2016-10-11
- Data Source
  KAKENHI-PROJECT-25293173
[Presentation] 肝炎・肝細胞癌誘導因子であるLTβ の発現様式を用いた肝細胞癌の個別化医療の可能性2015
- Author(s)
  渡邊丈久、藤江里美、徳永尭之、泉和寛、川崎剛、吉丸洋子、瀬戸山博子、福林光太郎、立山雅邦、田中基彦、佐々木裕
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  ホテル日航熊本
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25860543
[Presentation] Lymphotoxin-β　regulated by NF-κB is a useful biomarker related to poor prognosis in hepatocellular carcinoma.2015
- Author(s)
  Takehisa Watanabe, Satomi Fujie, Akiyuki Tokunaga, Kazuhiro Izumi, Takeshi Kawasaki, Yoko yoshimaru, Hiroko Setoyama, Kotaro Fukubayashi, Masakuni Tateyama, Motohiko Tanaka1, and Yutaka Sasaki.
- Organizer
  AASLD2015
- Place of Presentation
  SAN FRANCISCO, CA
- Year and Date
  2015-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860543
[Presentation] 当院におけるDAA登場後の移植後C型肝炎に対する治療の検討2015
- Author(s)
  渡邊丈久、川崎剛、吉丸洋子、立山雅邦、永濱裕康、室川剛廣、本田正樹、林田信太郎、阪本靖介、田中基彦、猪股裕紀洋、佐々木裕
- Organizer
  第51回日本移植学会総会
- Place of Presentation
  ホテル日航熊本
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-25860543
[Presentation] 「おなかの病気を考える」～よくわかる最新の話題～2015
- Author(s)
  渡邊丈久
- Organizer
  日本消化器病学会　九州支部　第85回市民公開講座
- Place of Presentation
  八代ハーモニーホール
- Year and Date
  2015-09-05
- Invited
- Data Source
  KAKENHI-PROJECT-25860543
[Presentation] Integrated proteomics analyses identified a phosphoprotein relevant to apoptosis resistance in human hepatocellular carcinoma2015
- Author(s)
  Naoe H, Hoshida Y, Yokote S, Fujie S, Watanabe T, Nagaoka K, Yamazoe T , Setoyama H, Tanaka M, Fujimoto J, Araki N, Sasaki Y
- Organizer
  The 65th annual meeting of the American association for the study of liver disease (AASLD2015)
- Place of Presentation
  San Francisco, USA
- Year and Date
  2015-11-13
- Data Source
  KAKENHI-PROJECT-25293173
[Presentation] 肝炎・肝細胞癌誘導因子であるLTβの発現様式を用いた肝細胞がんの個別化医療の可能性2015
- Author(s)
  渡邊丈久、田中基彦、佐々木裕
- Organizer
  第51回日本肝臓学会総会
- Place of Presentation
  熊本
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25293173
[Presentation] Human mercapto-albumin level is a useful biomarker of progression and 　functional property of human serum albumin in chronic liver disease2015
- Author(s)
  Setoyama H, Tanaka M, Naoe H, Tateyama M, Watanabe T, Yoshimaru Y, Fujie S, Oniki K, Saruwatari J, Watanabe H, Maruyama T, Sasaki Y
- Organizer
  Human mercapto-albumin level is a useful biomarker of progression and 　functional property of human serum albumin in chronic liver disease
- Place of Presentation
  San Francisco, USA
- Year and Date
  2015-11-13
- Data Source
  KAKENHI-PROJECT-25293173
[Presentation] Lymphotoxin-β regulated by NF-κB is a useful biomarker related to poor prognosis in hepatocellular carcinoma.2015
- Author(s)
  Watanabe T, Fujie S, Tokunaga T, Izumi K, Kawasaki T, Yoshimaru Y, Setoyama H, Fukubayashi K, Tateyama M, Tanaka M, and Sasaki Y
- Organizer
  3.Takehisa Watanabe, Satomi Fujie, Takayuki Tokunaga, Kazuhiro Izumi, Takeshi Kawasaki, Youko yoshimaru, Hiroko Setoyama, Kotaro Fukubayashi, Masakuni Tateyama, Motohiko Tanaka, and Yutaka Sasaki
- Place of Presentation
  San Francisco, USA
- Year and Date
  2015-11-13
- Data Source
  KAKENHI-PROJECT-25293173
[Presentation] 当科におけるソラフェニブ治療反応性の検討. 肝癌分子標的治療研究会2014
- Author(s)
  8.泉和寛、徳永尭之、川崎剛、藤江里美、吉丸洋子、渡邊丈久、瀬戸山博子、福林光太郎、田中基彦、佐々木裕
- Organizer
  肝癌分子標的治療研究会
- Place of Presentation
  兵庫
- Year and Date
  2014-06-29
- Data Source
  KAKENHI-PROJECT-25860543
[Presentation] ワークショップ「最新の遺伝子研究からみた肝臓病の現状と個別化医療への展望」肝炎・肝細胞癌誘導因子である L Tβの時空間的な発現制御メカこズムの解析2012
- Author(s)
  渡邊丈久、佐々木裕、他
- Organizer
  第48回日本肝臓学会総会
- Place of Presentation
  ポルテ金沢、金沢
- Year and Date
  2012-06-07
- Data Source
  KAKENHI-PROJECT-21390230
[Presentation] 門脈腫瘍侵襲を伴う進行肝細胞癌症例における食道胃静脈瘤の合併率と予後との関連についての検討
- Author(s)
  吉丸洋子、福林光太郎、村尾哲哉、渡邊丈久、立山雅邦、田中基彦、佐々木裕
- Organizer
  第21回日本門脈圧亢進症学会
- Place of Presentation
  東京
- Year and Date
  2014-09-12 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25860543
[Presentation] 進行肝細胞癌に対するソラフェニブと肝動注化学療法の位置付け
- Author(s)
  福林光太郎、田中基彦、立山雅邦、吉丸洋子、川崎剛、泉和寛、溝部典生、渡邊丈久、佐々木裕.
- Organizer
  JDDW2013
- Place of Presentation
  ｸﾞﾗﾝﾄﾞﾌﾟﾘﾝｽﾎﾃﾙ新高輪(東京）
- Data Source
  KAKENHI-PROJECT-25860543
[Presentation] 連施設におけるC型慢性肝炎に対するTelaprevir, Peg-IFNα2b, Rivavirin 3剤併用療法の治療効果の検討.
- Author(s)
  立山雅邦、田中基彦、泉和寛、川崎剛、溝部典生、吉丸洋子、渡邊丈久、福林光太郎、岩下博文、宮瀬志保、森下祐子、佐々木雅人、杉和洋、藤山重俊、佐々木裕.
- Organizer
  第17回日本肝臓学会大会(JDDW2013)
- Place of Presentation
  ｸﾞﾗﾝﾄﾞﾌﾟﾘﾝｽﾎﾃﾙ新高輪(東京）
- Data Source
  KAKENHI-PROJECT-25860543
[Presentation] アデフォビル長期投与における腎障害の検討.
- Author(s)
  溝部典生、川崎剛、泉和寛、吉丸洋子、渡邊丈久、福林光太郎、立山雅邦、田中基彦、佐々木裕.
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王ﾌﾟﾗｻﾞﾎﾃﾙ(東京）
- Data Source
  KAKENHI-PROJECT-25860543
[Presentation] 肝炎・肝細胞癌誘導因子である LTβ の慢性炎症におけるエピゲノム制御の解析
- Author(s)
  7.渡邊丈久、藤江里美、徳永尭之、泉和寛、川崎剛、吉丸洋子、瀬戸山博子、福林光太郎、立山雅邦、田中基彦、佐々木裕
- Organizer
  第50回日本肝癌研究会
- Place of Presentation
  京都
- Year and Date
  2014-06-05 – 2014-06-06
- Data Source
  KAKENHI-PROJECT-25860543
[Presentation] 肝炎・肝細胞癌誘導因子であるLTβの時空間的な発現制御メカニズムの解析
- Author(s)
  渡邊　丈久、石原　宏、中尾　光善、佐々木　裕
- Organizer
  第48回日本肝臓学会総会　ワークショップ「最新の遺伝子研究からみた肝臓病の現状と個別化医療への展望」
- Place of Presentation
  ホテル日航金沢（金沢市）
- Data Source
  KAKENHI-PROJECT-21390230
[Presentation] 当院におけるTelaprevir, Peg-IFN, RBV 3剤併用療法の副作用、初期治療効果、投与量に関する検討
- Author(s)
  立山雅邦、田中基彦、泉和寛、川崎剛、溝部典生、吉丸洋子、渡邊丈久、福林光太郎、佐々木裕.
- Organizer
  第49回日本肝臓学会総会
- Place of Presentation
  京王ﾌﾟﾗｻﾞﾎﾃﾙ（東京）
- Data Source
  KAKENHI-PROJECT-25860543
[Presentation] 腹部超音波での描出困難例の結節に対する仮想超音波でのRFAの治療支援の経験
- Author(s)
  6.立山雅邦、田中基彦、泉和寛、藤江里美、川崎剛、吉丸洋子、渡邊丈久、瀬戸山博子、福林光太郎、佐々木裕
- Organizer
  第50回日本肝癌研究会
- Place of Presentation
  京都
- Year and Date
  2014-06-05 – 2014-06-06
- Data Source
  KAKENHI-PROJECT-25860543
[Presentation] C型肝硬変におけるペグインターフェロン、リバビリン併用療法（3剤併用療法を含む）の現状とその予後に関しての検討
- Author(s)
  立山雅邦、田中基彦、徳永尭之、泉和寛、川崎剛、藤江里美、吉丸洋子、渡邊丈久、瀬戸山博子、福林光太郎、佐々木裕
- Organizer
  第21回日本門脈圧亢進症学会
- Place of Presentation
  東京
- Year and Date
  2014-09-12 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25860543
[Presentation] 科および関連施設におけるPeginterferonα2a投与症例の検討
- Author(s)
  立山雅邦、田中基彦、泉和寛、藤江里美、川崎剛、吉丸洋子、渡邊丈久、瀬戸山博子、福林光太郎、佐々木裕、原岡克樹、大内田義博、宮瀬志保、藤山重俊、杉和洋、佐々木雅人、坂井良成、山崎雅史
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2014-04-23 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-25860543
[Presentation] 肝細胞代謝におけるヒストン脱メチル化酵素LSD2の機能と代謝性肝疾患
- Author(s)
  長岡克弥、日野信次朗、渡邊丈久、直江秀昭、坂元顕久、阿南浩太郎、高瀬隆太、横手誠一郎、中尾光善、佐々木裕
- Organizer
  第50回日本臨床分子医学会学術集会
- Place of Presentation
  東京国際ﾌｫｰﾗﾑ
- Data Source
  KAKENHI-PROJECT-25860543
[Presentation] 肝予備能良好進行肝細胞癌の治療成績と長期生存例における後治療の意義
- Author(s)
  福林光太郎、田中基彦、泉和寛、藤江里美、川崎剛、吉丸洋子、渡邊丈久、瀬戸山博子、立山雅邦、佐々木裕
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2014-04-23 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-25860543
[Presentation] Telaprevir/Peginterferon α2b/Ribavirin 3剤併用療法におけるPSE、脾摘の有用性.
- Author(s)
  立山雅邦、田中基彦、泉和寛、川崎剛、藤江里美、吉丸洋子、渡邊丈久、瀬戸山博子、福林光太郎、宮瀬志保、藤山重俊、佐々木裕
- Organizer
  第20回日本門脈圧亢進症学会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-25860543
[Presentation] 初回conventional-TACE症例の治療効果とTACE不応因子の解析
- Author(s)
  福林光太郎、田中基彦、泉和寛、川崎剛、藤江里美、吉丸洋子、渡邊丈久、瀬戸山博子、立山雅邦、前田誠士、佐々木裕
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2014-04-23 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-25860543

1. SASAKI Yutaka (70235282)

# of Collaborated Projects: 9 results

# of Collaborated Products: 66 results
2. NAOE Hideaki (30599246)

# of Collaborated Projects: 9 results

# of Collaborated Products: 21 results
3. FUJIMOTO Jiro (90199373)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
4. ARAKI Norie (80253722)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
5. NAGAOKA KATSUYA (00759524)

# of Collaborated Projects: 3 results

# of Collaborated Products: 27 results
6. NAGAHAMA Hiroyasu (60381000)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TANAKA Motohiko (20346985)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
8. 田中靖人 (90336694)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. NAKAO MITSUYOSHI (00217663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. Shono Takashi (40632667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 吉村亮二 (20782569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 山添太士 (20736219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 古田陽輝 (00869513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. WATANABE Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. MARUYAMA Toru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. SARUWATARI Junji

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
17. KOGA Tomoaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 小田切優樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 鬼木健太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
20. 五十川正記

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 瀬戸山博子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

WATANABE TAKEHISA 渡邊 丈久

WATANABE Takehisa 渡邊 丈久

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Elucidation of Different cccDNA Control Mechanisms Among HBV Genotypes Using Novel Epigenomic Analysis TechniquesPrincipal Investigator

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the analysis of the regulatory mechanism in HBV-cccDNA using a new epigenetic methodPrincipal Investigator

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The impact of the changes in serum exosomal miRNA profiles induced by DAAs therapy on liver carcinogenesisPrincipal Investigator

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Analysis of the higher-order regulatory mechanism of LT-beta epigenome, leading to clinical application.Principal Investigator

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[Book] 最新医学別冊 改訂第2版（新しい診断と治療ABC, 44 肝硬変)2013

WATANABE TAKEHISA 渡邊丈久

WATANABE Takehisa 渡邊丈久

[Book] 最新医学別冊改訂第2版（新しい診断と治療ABC, 44 肝硬変)2013

[Book] 専門医のための消化器病学第2版(肝細胞癌と癌幹細胞）2013

[Book] 第39回日本急性肝不全研究会　藤原研司先生メモリアル＜追悼文集・記録集＞2013