NAGASHIMA Yu 長島優

… Alternative Names

Nagashima Yu 長島優

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Researcher Number	20635586
Other IDs
Affiliation (Current)	2025: 浜松医科大学, 光医学総合研究所, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 浜松医科大学, 光尖端医学教育研究センター, 教授 2018 – 2019: 東京大学, 医学部附属病院, 助教 2016 – 2017: 東京大学, 大学院理学系研究科(理学部), 特任研究員 2015: 東京大学, 医学部附属病院, 特別研究員PD 2014: 東京大学, 医学部附属病院, 日本学術振興会特別研究員(PD) 2012 – 2013: 東京大学, 医学部附属病院, その他
Review Section/Research Field	Principal Investigator Neurology / Basic Section 52020:Neurology-related Except Principal Investigator Basic Section 21030:Measurement engineering-related / Basic Section 52020:Neurology-related / Basic Section 56060:Ophthalmology-related
Keywords	Principal Investigator ラマン分光法 / 脂質イメージング / 神経筋疾患 / 脳神経内科 / サルコペニア / 脂質 / アミロイドβ / フォトニック結晶 / バイオマーカー / アルツハイマー病 … More / スパースコーディング / 分光顕微鏡画像 / 独立成分分析 / 振動スペクトル / ラマン分光 / α-シヌクレイン / パーキンソン病 / シヌクレイン / ハンチントン舞踏病 … More Except Principal Investigator 光生体計測 / ラマン分光法 / 凝集体 / スプライソソーム / 筋萎縮性側索硬化症 / spliceosome / granule / OPTN / FUS / ALS / 細胞死機構 / ラマン顕微鏡 / 網膜光障害 Less

Development of measurement system using light and ultrasound for inflammatory and degenerative diseases
- Principal Investigator
  
  大川晋平
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 21030:Measurement engineering-related
- Research Institution
  Hamamatsu University School of Medicine
Estimation of pathological mechanism through lipid composition imaging of adipose tissue in muscle fibers from patients of neuromuscular disordersPrincipal Investigator
- Principal Investigator
  
  長島優
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hamamatsu University School of Medicine
網膜光障害感受性遺伝子Ｐａｎｋ４の機能追究とラマン分光顕微鏡による鉄代謝解析
- Principal Investigator
  
  大石健太郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Hamamatsu University School of Medicine
ALS発症におけるOPTNの新規核内機能：スプライソソーム異常と凝集体形成
- Principal Investigator
  
  大坪正史
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hamamatsu University School of Medicine
過完備独立基底の内因性特徴に基いた分光顕微鏡画像のデータマイニングPrincipal Investigator
- Principal Investigator
  
  長島優
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
Development of photonic crystal based sensor for measuring blood biomarkers of Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  Nagashima Yu
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  The University of Tokyo
Development of label-free vibrational spectroscopy to quantify and visualize alpha-synuclein molecules in vivoPrincipal Investigator
- Principal Investigator
  
  Nagashima Yu
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  The University of Tokyo
ラマン分光法によるハンチントン病凝集タンパク質の定量的モニタリングシステムの開発Principal Investigator
- Principal Investigator
  
  長島優
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Neurology
- Research Institution
  The University of Tokyo

All 2024 2023 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Patent Other

[Journal Article] Rare Co-occurrence of Spinal Cord Hemorrhage from Radiation-induced Cavernous Hemangioma and Classical Hodgkin Lymphoma Post-transplant Lymphoproliferative Disorder2024
- Author(s)
  Takahiro Shimizu, Yu Nagashima, Takashi Matsukawa, Akihiko Mitsutake, Mizuho Kawai, Yurino Horiuchi, Keishi Yokoyama, Kensuke Takaoka, Yuya Kurihara, Kazuhiro Toyama, Kaori Sakuishi, Mineo Kurokawa, Tatsushi Toda
- Journal Title
  
  Intern. Med.
  
  Volume: 63 Issue: 20 Pages: 2853-2856
- DOI
  10.2169/internalmedicine.2898-23
- ISSN
  0918-2918, 1349-7235
- URL
  https://pure.teikyo.jp/en/publications/94adff3a-6080-4609-bc8a-efd9ef68a873
- Year and Date
  2024-10-15
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06925
[Journal Article] Enhanced spectral resolution for broadband coherent anti-Stokes Raman spectroscopy2020
- Author(s)
  Sinjab Faris、Hashimoto Kazuki、Zhao Xuanqiang、Nagashima Yu、Ideguchi Takuro
- Journal Title
  
  Optics Letters
  
  Volume: 45 Issue: 6 Pages: 1515-1515
- DOI
  10.1364/ol.388624
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04729, KAKENHI-PROJECT-18F18012
[Journal Article] Quantifying normal and parkinsonian gait features from home movies: Practical application of a deep learning?based 2D pose estimator2019
- Author(s)
  Sato Kenichiro、Nagashima Yu、Mano Tatsuo、Iwata Atsushi、Toda Tatsushi
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 11 Pages: 0223549-0223549
- DOI
  10.1371/journal.pone.0223549
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17027, KAKENHI-PUBLICLY-18H04729
[Journal Article] Estimating acceleration time point of respiratory decline in ALS patients: A novel metric2019
- Author(s)
  Sato Kenichiro、Iwata Atsushi、Kurihara Masanori、Nagashima Yu、Mano Tatsuo、Toda Tatsushi
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 403 Pages: 7-12
- DOI
  10.1016/j.jns.2019.05.031
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17027, KAKENHI-PUBLICLY-18H04729, KAKENHI-PROJECT-19J10924
[Journal Article] Molecular contrast on phase-contrast microscope2019
- Author(s)
  Toda Keiichiro、Tamamitsu Miu、Nagashima Yu、Horisaki Ryoichi、Ideguchi Takuro
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 1-7
- DOI
  10.1038/s41598-019-46383-6
- NAID
  120006711373
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04729, KAKENHI-PROJECT-19J12981
[Journal Article] 創薬における超高速ラマン分光法の活用2018
- Author(s)
  長島優, 橋本和樹, 大間知潤子, 井手口拓郎
- Journal Title
  
  光アライアンス
  
  Volume: 29(6) Pages: 21-26
- Data Source
  KAKENHI-PUBLICLY-18H04729
[Journal Article] Atypical parkinsonism caused by Pro105Leu mutation of prion protein: A broad clinical spectrum.2016
- Author(s)
  Mano KK, Matsukawa T, Mitsui J, Ishiura H, Tokushige S, Takahashi Y, Sato NS, Nakamoto FK, Ichikawa Y, Nagashima Y, Terao Y, Shimizu J, Hamada M, Uesaka Y, Oyama G, Ogawa G, Yoshimura J, Doi K, Morishita S, Tsuji S, Goto J.
- Journal Title
  
  Neurol Genet.
  
  Volume: 2 Issue: 1 Pages: 1-9
- DOI
  10.1212/nxg.0000000000000048
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19498, KAKENHI-PROJECT-26860660, KAKENHI-PROJECT-13J06016
[Patent] 運動失調軽減装置2015
- Inventor(s)
  長島　優、相阪　有理、長野　智晃
- Industrial Property Rights Holder
  長島　優、相阪　有理、長野　智晃
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-151110
- Filing Date
  2015-07-30
- Data Source
  KAKENHI-PROJECT-26860660
[Patent] 眼鏡型ウェアラブル装置2015
- Inventor(s)
  長島　優
- Industrial Property Rights Holder
  長島　優
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-139267
- Filing Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-26860660
[Presentation] Structural imaging technology to elucidate the chemical structure of aggregates in the brain2023
- Author(s)
  Yu Nagashima
- Organizer
  日本神経化学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K06925
[Presentation] ラマン分光顕微鏡を用いた患者由来組織のラベルフリー脂質イメージング技術の開発2023
- Author(s)
  長島　優
- Organizer
  日本生体医工学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K06925
[Presentation] Label-free imaging of abnormal lipid accumulation in muscle fibers from inclusion body myositis patients using Raman spectroscopy2019
- Author(s)
  Yu Nagashima, Jun Shimizu, Atsushi Iwata, Kosuke Yoshioka, Junko Omachi, Junji Yumoto, Makoto Kuwata-Gonokami, Tatsushi Toda
- Organizer
  Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04729
[Presentation] Label-free visualization of abnormal lipid accumulation in rimmed vacuoles in muscle fibers from inclusion body myositis patients2019
- Author(s)
  Yu Nagashima, Jun Shimizu, Atsushi Iwata, Tatsushi Toda
- Organizer
  International Conference on the Bioscience of Lipids
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04729
[Presentation] 非線形ラマン分光およびフォトニック構造を用いた診断技術の開発2017
- Author(s)
  長島　優
- Organizer
  日本物理学会秋季大会
- Invited
- Data Source
  KAKENHI-PROJECT-26860660
[Presentation] Spatial distribution of Raman spectra within amyloid beta aggregates in vitro2017
- Author(s)
  Yu Nagashima, Atsushi Iwata
- Organizer
  第7回新潟大学脳研究所共同研究拠点国際シンポジウム
- Place of Presentation
  新潟大学(新潟県新潟市)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860660
[Presentation] 非線形ラマン分光およびフォトニック構造を用いた診断技術の開発2017
- Author(s)
  長島　優
- Organizer
  日本物理学会秋季大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K16114
[Presentation] Spatially localized Raman shifts within amyloid beta aggregates in vitro2016
- Author(s)
  Yu Nagashima, Atsushi Iwata
- Organizer
  2016分子分光国際シンポジウム
- Place of Presentation
  九州大学(福岡県福岡市)
- Year and Date
  2016-07-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860660
[Presentation] ポリマー製フォトニック結晶を用いた非標識光学バイオセンサーの開発とアミロイドβの検出2016
- Author(s)
  遠藤達郎・長島優・岩田淳
- Organizer
  応用物理学会
- Place of Presentation
  東京都
- Year and Date
  2016-03-21
- Data Source
  KAKENHI-PROJECT-26860660
[Presentation] Spatial distribution of Raman shifts within amyloid beta aggregates in vitro2016
- Author(s)
  Yu Nagashima, Atsushi Iwata
- Organizer
  Society for Neuroscience 2016
- Place of Presentation
  San Diego (USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860660
[Presentation] Label-free monitoring of amyloid β aggregation using polymer-based photonic crystal.2015
- Author(s)
  Tatsuro Endo, Yu Nagashima, Atsushi Iwata
- Organizer
  応用物理学会
- Place of Presentation
  愛知県
- Year and Date
  2015-09-04
- Data Source
  KAKENHI-PROJECT-26860660
[Presentation] ポリマー製フォトニック結晶を用いた神経変性疾患検査への取り組み2015
- Author(s)
  遠藤達郎・長島優・岩田淳
- Organizer
  光科学異分野横断萌芽研究会
- Place of Presentation
  愛知県
- Year and Date
  2015-08-05
- Data Source
  KAKENHI-PROJECT-26860660
[Presentation] 乳児期より精神発達遅滞を伴い、30歳代から歩行障害と嚥下障害が急速に進行、WDR45遺伝子変異を認めた40歳女性例2014
- Author(s)
  内尾直裕, 長島優, 平賢一郎, 市川弥生子, 寺尾安生, 松本直通, 辻省次
- Organizer
  第209回日本神経学会関東・甲信越地方会
- Place of Presentation
  東京都
- Year and Date
  2014-06-07
- Data Source
  KAKENHI-PROJECT-26860660
[Presentation] Quantitative analysis of surface EMG for pediatric neuromuscular disorders
- Author(s)
  Mana Higashihara, Masahiro Sonoo, Akihiko Ishiyama, Yu Nagashima, Haruo Uesugi, Madoka Mori, Miho Murata, Shigeo Murayama, Hirofumi Komaki
- Organizer
  the AANEM 61st Annual Meeting 2014
- Place of Presentation
  米国
- Year and Date
  2014-10-29 – 2014-11-01
- Data Source
  KAKENHI-PROJECT-26860660
[Presentation] 小児神経筋疾患の診断における表面筋電図の定量解析法(CI法)の有用性　非侵襲的に神経原性疾患と筋疾患を鑑別する
- Author(s)
  東原真奈, 園生雅弘, 石山昭彦, 長島優, 上杉春雄, 森まどか, 村田美穂, 村山繁雄, 小牧宏文
- Organizer
  第44回日本臨床神経生理学会学術大会
- Place of Presentation
  福岡県
- Year and Date
  2014-11-19 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-26860660
[Presentation] ラマン分光法によるポリグルタミン凝集タンパク質の非染色・非標識での検出法の開発
- Author(s)
  長島　優, 岩田　淳, 辻省次
- Organizer
  第55回日本神経学会総会
- Place of Presentation
  福岡県
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26860660
[Presentation] ラマン分光法によるポリグルタミン封入体の観測
- Author(s)
  長島　優, 岩田　淳, 辻省次
- Organizer
  平成26年応用物理学会量子エレクトロニクス研究会
- Place of Presentation
  長野県
- Year and Date
  2014-12-19 – 2014-12-21
- Data Source
  KAKENHI-PROJECT-26860660
[]

1. 大石健太郎 (80345826)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 大坪正史 (10327653)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 大川晋平 (20432049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 田村和輝 (40822614)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 中村友彦 (00437039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 瀬藤光利 (20302664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 前田明子 (20646799)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 間野達雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 大山彦光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAGASHIMA Yu 長島 優

Nagashima Yu 長島 優

Research Projects

Research Products

Co-Researchers

Development of measurement system using light and ultrasound for inflammatory and degenerative diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Estimation of pathological mechanism through lipid composition imaging of adipose tissue in muscle fibers from patients of neuromuscular disordersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

網膜光障害感受性遺伝子Ｐａｎｋ４の機能追究とラマン分光顕微鏡による鉄代謝解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ALS発症におけるOPTNの新規核内機能：スプライソソーム異常と凝集体形成

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

過完備独立基底の内因性特徴に基いた分光顕微鏡画像のデータマイニングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Development of photonic crystal based sensor for measuring blood biomarkers of Alzheimer's diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of label-free vibrational spectroscopy to quantify and visualize alpha-synuclein molecules in vivoPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ラマン分光法によるハンチントン病凝集タンパク質の定量的モニタリングシステムの開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Rare Co-occurrence of Spinal Cord Hemorrhage from Radiation-induced Cavernous Hemangioma and Classical Hodgkin Lymphoma Post-transplant Lymphoproliferative Disorder2024

Author(s)

Journal Title

DOI

ISSN

URL

Year and Date

Language

Data Source

[Journal Article] Enhanced spectral resolution for broadband coherent anti-Stokes Raman spectroscopy2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Quantifying normal and parkinsonian gait features from home movies: Practical application of a deep learning?based 2D pose estimator2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Estimating acceleration time point of respiratory decline in ALS patients: A novel metric2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular contrast on phase-contrast microscope2019

Author(s)

Journal Title

DOI

NAGASHIMA Yu 長島優

Nagashima Yu 長島優