Oinuma Ken-Ichi 老沼研一

… Alternative Names

老沼研一オイヌマケンイチ

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Researcher Number	20635619
Other IDs	https://orcid.org/0000-0001-8313-5143
Affiliation (Current)	2025: 大阪公立大学, 大学院医学研究科, 講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 大阪公立大学, 大学院医学研究科, 講師 2015 – 2019: 大阪市立大学, 大学院医学研究科, 助教 2014: 筑波大学, 生命環境系, 助教
Review Section/Research Field	Principal Investigator Basic Section 49050:Bacteriology-related / Bacteriology (including mycology) / Applied biochemistry Except Principal Investigator Infectious disease medicine
Keywords	Principal Investigator QscR / RhlR / クオラムセンシング / 緑膿菌 / 分子機能解析 / アシルホモセリンラクトンレセプター / シグナル伝達 / 細菌 / 可溶性 / タンパク質発現 … More / レポーターアッセイ / タンパク質精製 / AHLレセプター / 芳香族ポリマ－ / Aspergillus niger / 加水分解酵素 / 芳香族ポリマー … More Except Principal Investigator 臨床ゲノム / 日和見感染症 / 科学的・効率的な感染制御の実践 / 新規耐性遺伝子の検出 / 耐性因子のリスト化 / 網羅的遺伝子検出 / カルバペネマーゼ / アシネトバクター / 全ゲノム解析 / プラスミド / 薬剤耐性菌 Less

緑膿菌の病原性抑制薬の開発に向けたクオラムセンシング制御機構の基盤研究Principal Investigator
- Principal Investigator
  
  老沼研一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Osaka Metropolitan University
Molecular epidemiology of drug-resistant Acinetobacter
- Principal Investigator
  
  Kaneko Yukihiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Osaka City University
Functional analysis of AHL receptors toward comprehensive understanding of the quorum sensing mechanism in Pseudomonas aeruginosaPrincipal Investigator
- Principal Investigator
  
  Oinuma Ken-Ichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Osaka City University
Screening and analysis of aromatic polymer-hydrolyzing enzymesPrincipal Investigator
- Principal Investigator
  
  Oinuma Ken-Ichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  Osaka City University
  University of Tsukuba

All 2024 2023 2022 2020 2019 2018 2017 2016 2015 Other

All Journal Article Presentation Other

[Journal Article] Discovery of a LuxR-type regulator involved in isoniazid-dependent gene regulation in Mycobacterium smegmatis2023
- Author(s)
  Arata Sakiyama, Ken-Ichi Oinuma, Yukihiro Kaneko
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 29 Issue: 3 Pages: 322-328
- DOI
  10.1016/j.jiac.2022.12.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07072
[Journal Article] Identification of a mycobacterial hydrazidase, an isoniazid-hydrolyzing enzyme2023
- Author(s)
  Arata Sakiyama, Yukihiro Kaneko, Ken-Ichi Oinuma
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1
- DOI
  10.1038/s41598-023-35213-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07072
[Journal Article] Genome-Based Epidemiological Analysis of 13 Acinetobacter Strains Isolated from Blood Cultures of Hospitalized Patients from a University Hospital in Japan2019
- Author(s)
 Oinuma KI, Suzuki M, Nakaie K, Sato K, Saeki K, Sakiyama A, Takizawa E, Niki M, Niki M, Yamada K, Shibayama K, Kakeya H, Kaneko Y
- Journal Title
 
 Jpn J Infect Dis
 
 Volume: 72 Issue: 4 Pages: 274-280
- DOI
 10.7883/yoken.JJID.2018.403
- NAID
 130007682332
- ISSN
 1344-6304, 1884-2836
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-17K08846, KAKENHI-PROJECT-17K10026, KAKENHI-PROJECT-17K15689
[Journal Article] The Pseudomonas aeruginosa orphan quorum sensing signal receptor QscR regulates global quorum sensing gene expression by activating a single linked operon2018
- Author(s)
  Ding F, Oinuma K, Smalley NE, Schaefer AL, Hamwy O, Greenberg EP, Dandekar AA
- Journal Title
  
  mBio
  
  Volume: 9 Issue: 4
- DOI
  10.1128/mbio.01274-18
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15689
[Journal Article] Successful Treatment of Intestinal Mycosis Caused by a Simultaneous Infection with Lichtheimia ramosa and Aspergillus calidoustus2018
- Author(s)
 Kaneko Y, Oinuma KI, Terachi T, Arimura Y, Niki M, Yamada K, Kakeya H, Mizutani T
- Journal Title
 
 Intern. Med.
 
 Volume: 57 Issue: 16 Pages: 2421-2424
- DOI
 10.2169/internalmedicine.0254-17
- NAID
 130007435932
- ISSN
 0918-2918, 1349-7235
- Year and Date
 2018-08-15
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-17K10026
[Journal Article] Clinical characteristics of bacteremia caused by extended-spectrum beta-lactamase-producing Escherichia coli at a tertiary hospital2017
- Author(s)
  Namikawa H., Yamada K., Fujimoto H., Oinuma K., Tochino Y., Takemoto Y., Kaneko Y., Shuto T. and Kakeya H.
- Journal Title
  
  Internal Medicine
  
  Volume: 印刷中
- NAID
  130005773825
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26850060
[Journal Article] Structural basis of the substrate recognition of hydrazidase isolated from Microbacterium sp. strain HM58-2, which catalyzes acylhydrazide compounds as its sole carbon source2017
- Author(s)
  Akiyama T., Ishii M., Takuwa A., Oinuma K., Sasaki Y., Takaya N. and Yajima S.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 482 Issue: 4 Pages: 1007-1012
- DOI
  10.1016/j.bbrc.2016.11.148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26850060, KAKENHI-PROJECT-15K07369
[Journal Article] Alternative fermentation pathway of cinnamic acid production via phenyllactic acid2016
- Author(s)
  Masuo S., Kobayashi Y., Oinuma K. and Takaya N.
- Journal Title
  
  Applied Microbiology and Biotechnology
  
  Volume: 100 Issue: 20 Pages: 8701-8709
- DOI
  10.1007/s00253-016-7623-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26850060
[Journal Article] An Intrinsic Strain of Colistin-resistant Acinetobacter Isolated from a Japanese Patient2016
- Author(s)
 Takizawa E., Yamada K., Oinuma K., Sato K., Niki M., Namikawa H., Fujimoto H., Asai K., Kaneko Y. and Kakeya H.
- Journal Title
 
 Intern. Med.
 
 Volume: 55 Issue: 16 Pages: 2301-2306
- DOI
 10.2169/internalmedicine.55.6807
- NAID
 130005169382
- ISSN
 0918-2918, 1349-7235
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-26850060, KAKENHI-PROJECT-15K09185
[Journal Article] Draft genome sequence of Microbacterium sp. strain HM58-2, which hydrolyzes acylhydrazides2016
- Author(s)
  Akiyama T., Ishige T., Kanesaki Y., Ito S., Oinuma K., Takaya N., Sasaki Y. and Yajima S.
- Journal Title
  
  Genome Announcements
  
  Volume: 4 Issue: 3
- DOI
  10.1128/genomea.00554-16
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26850060, KAKENHI-PROJECT-15K07369
[Journal Article] Genome sequence of an Acinetobacter baumannii strain carrying three acquired carbapenemase genes2016
- Author(s)
  Oinuma K., Suzuki M., Sato K., Nakaie K., Niki M., Takizawa E., Niki M., Shibayama K., Yamada K., Kakeya H. and Kaneko Y.
- Journal Title
  
  Genome Announcements
  
  Volume: 4 Issue: 6
- DOI
  10.1128/genomea.01290-16
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26850060
[Journal Article] Two unusual cases of successful treatment of hypermucoviscous Klebsiella pneumoniae invasive syndrome2016
- Author(s)
  Namikawa H., Yamada K., Fujimoto H., Oinuma K., Tochino Y., Takemoto Y., Kaneko Y., Shuto T. and Kakeya H.
- Journal Title
  
  BMC Infectious Diseases
  
  Volume: 16 Issue: 1 Pages: 680-680
- DOI
  10.1186/s12879-016-2011-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26850060, KAKENHI-PROJECT-15K08649
[Presentation] Acinetobacter baumannii OCU_Ac16b株の莢膜型転換メカニズムの解析2024
- Author(s)
  薩仁朝格吐, 榮山新, 老沼研一, 鈴木仁人, 坪内泰志, 仁木満美子, 金子幸弘
- Organizer
  第58回緑膿菌感染症研究会
- Data Source
  KAKENHI-PROJECT-22K07072
[Presentation] Mycobacterium smegmatisが有するイソニアジド依存的な遺伝子制御に関与するLuxR型制御因子の解析2023
- Author(s)
  榮山新, 金子幸弘, 老沼研一
- Organizer
  第7回抗酸菌研究会
- Data Source
  KAKENHI-PROJECT-22K07072
[Presentation] Acinetobacter baumannii OCU_Ac16b-L株の厚莢膜形成メカニズムの解析2023
- Author(s)
  薩仁朝格吐, 榮山新, 老沼研一, 鈴木仁人, 佐伯康匠, 坪内泰志, 仁木満美子, 山田康一, 柴山恵吾, 掛屋弘, 金子幸弘
- Organizer
  第57回緑膿菌感染症研究会
- Data Source
  KAKENHI-PROJECT-22K07072
[Presentation] Persisterに対する抗菌化学療法2022
- Author(s)
  老沼研一
- Organizer
  第65回日本感染症学会中日本地方会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K07072
[Presentation] 緑膿菌クオラムセンシング制御因子RhlRの組換え大腸菌を用いた機能解析2020
- Author(s)
  老沼研一, 矢守志穏, 松岡俊佑, 金子幸弘
- Organizer
  第54回緑膿菌感染症研究会
- Data Source
  KAKENHI-PROJECT-17K15689
[Presentation] 当院で分離されたカルバペネム高度耐性Acinetobacter baumannii株のカルバペネマーゼ遺伝子の周辺構造と接合伝達性2019
- Author(s)
  老沼研一, 鈴木仁人, 佐伯康匠, 坪内泰志, 仁木満美子, 山田康一, 柴山恵吾, 掛屋弘, 金子幸弘
- Organizer
  第53回緑膿菌感染症研究会学術集会
- Data Source
  KAKENHI-PROJECT-17K15689
[Presentation] アシネトバクター属細菌の内因性因子によるカルバペネム耐性獲得機構の解析2019
- Author(s)
  榮山新, 老沼研一, 金子幸弘
- Organizer
  第53回緑膿菌感染症研究会学術集会
- Data Source
  KAKENHI-PROJECT-17K15689
[Presentation] 当院で分離されたカルバペネム高度耐性Acinetobacter baumannii株のカルバペネマーゼ遺伝子の周辺構造と接合伝達性2019
- Author(s)
  老沼研一, 鈴木仁人, 佐伯康匠, 坪内泰志, 仁木満美子, 山田康一, 柴山恵吾, 掛屋弘, 金子幸弘
- Organizer
  第53回緑膿菌感染症研究会
- Data Source
  KAKENHI-PROJECT-17K10026
[Presentation] アシネトバクター属細菌の内因性因子によるカルバペネム耐性獲得機構の解析2019
- Author(s)
  榮山新, 老沼研一, 金子幸弘
- Organizer
  第53回緑膿菌感染症研究会
- Data Source
  KAKENHI-PROJECT-17K10026
[Presentation] Molecular characterization of Pseudomonas aeruginosa quorum sensing signal receptor RhlR2019
- Author(s)
  Ken-Ichi Oinuma
- Organizer
  ERATO-MiCS International Symposium on Sociomicrobiology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15689
[Presentation] 緑膿菌クオラムセンシングシグナルレセプターRhlRの大腸菌による発現と解析2019
- Author(s)
  老沼研一, 秦大樹, 金子幸弘
- Organizer
  第33回バイオフィルム学会学術集会
- Data Source
  KAKENHI-PROJECT-17K15689
[Presentation] 当院で分離されたカルバペネム高度耐性アシネトバクター株の耐性因子の特定と解析2018
- Author(s)
  老沼研一, 鈴木仁人, 佐藤佳奈子, 佐伯康匠, 中家清隆, 滝沢恵津子, 仁木誠, 仁木満美子, 山田康一, 柴山恵吾, 掛屋弘, 金子幸弘
- Organizer
  第52回緑膿菌感染症研究会
- Data Source
  KAKENHI-PROJECT-17K10026
[Presentation] 散発事例でのAcinetobacter baumanniiにおけるPOT法とMLSTでの遺伝子型の相違2018
- Author(s)
  榮山新, 老沼研一, 鈴木仁人, 佐藤佳奈子, 佐伯康匠, 中家清隆, 滝沢恵津子, 仁木誠, 仁木満美子, 山田康一, 柴山恵吾, 掛屋弘, 金子幸弘
- Organizer
  第52回緑膿菌感染症研究会
- Data Source
  KAKENHI-PROJECT-17K10026
[Presentation] NDM型とTMB型の2種のメタロ-β-ラクタマーゼを有するアシネトバクター属臨床分離株の発見と解析2017
- Author(s)
  老沼研一, 鈴木仁人, 佐藤佳奈子, 佐伯康匠, 中家清隆, 滝沢恵津子, 仁木誠, 仁木満美子, 山田康一, 柴山恵吾, 掛屋弘, 金子幸弘
- Organizer
  第87回日本感染症学会西日本地方会学術集会・第60回日本感染症学会中日本地方会学術集会・第65回日本化学療法学会西日本支部総会
- Data Source
  KAKENHI-PROJECT-17K10026
[Presentation] 当院で血液培養より分離されたアシネトバクター属細菌の分子疫学解析2017
- Author(s)
  金子幸弘, 老沼研一, 佐藤佳奈子, 鈴木仁人, 柴山恵吾, 滝沢恵津子, 仁木誠, 中家清隆, 仁木満美子, 山田康一, 掛屋弘
- Organizer
  第28回日本臨床微生物学会総会・学術集会
- Place of Presentation
  長崎ブリックホール, 長崎新聞文化ホール, 長崎県医師会館（長崎県長崎市）
- Year and Date
  2017-01-20
- Data Source
  KAKENHI-PROJECT-26850060
[Presentation] 血液由来のAcinetobacter baumanniiのPOT法とMLSTによる遺伝子型の比較2017
- Author(s)
  榮山新, 老沼研一, 鈴木仁人, 佐藤佳奈子, 佐伯康匠, 中家清隆, 滝沢恵津子, 仁木誠, 仁木満美子, 山田康一, 柴山恵吾, 掛屋弘, 金子幸弘
- Organizer
  第87回日本感染症学会西日本地方会学術集会・第60回日本感染症学会中日本地方会学術集会・第65回日本化学療法学会西日本支部総会
- Data Source
  KAKENHI-PROJECT-17K10026
[Presentation] ゲノム情報に基づくアシネトバクター属臨床分離株の分子疫学解析2017
- Author(s)
  老沼研一, 鈴木仁人, 佐藤佳奈子, 中家清隆, 滝沢恵津子, 仁木誠, 仁木満美子, 山田康一, 柴山恵吾, 掛屋弘, 金子幸弘
- Organizer
  第91回日本感染症学会総会・学術講演会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2017-04-06
- Data Source
  KAKENHI-PROJECT-26850060
[Presentation] POT法およびMLST法によるアシネトバクター属臨床分離株の遺伝子型解析2017
- Author(s)
  老沼研一, 鈴木仁人, 佐藤佳奈子, 中家清隆, 滝沢恵津子, 仁木誠, 仁木満美子, 山田康一, 柴山恵吾, 掛屋弘, 金子幸弘
- Organizer
  第51回緑膿菌感染症研究会学術集会
- Place of Presentation
  レンブラントホテル大分（大分県大分市）
- Year and Date
  2017-02-10
- Data Source
  KAKENHI-PROJECT-26850060
[Presentation] 遺伝子組換え大腸菌を用いたフェニル乳酸生産に影響を与える遺伝子の発現解析2016
- Author(s)
  宮川寛規, 川口秀夫, 荻野千秋, 老沼研一, 高谷直樹, 近藤昭彦
- Organizer
  第68回日本生物工学会大会
- Place of Presentation
  富山国際会議場, ANAクラウンプラザホテル富山（富山県富山市）
- Year and Date
  2016-09-28
- Data Source
  KAKENHI-PROJECT-26850060
[Presentation] 侵襲性肺ムーコル症マウスモデルにおけるRhizopus oryzae特異的分泌抗原の有用性の検討2016
- Author(s)
  佐藤佳奈子, 老沼研一, 山田康一, 掛屋弘, 金子幸弘
- Organizer
  第60回日本医真菌学会総会・学術集会
- Place of Presentation
  東京都立産業貿易センター台東館（東京都台東区）
- Year and Date
  2016-10-01
- Data Source
  KAKENHI-PROJECT-26850060
[Presentation] Discovery and analysis of a novel Rhizopus antigen as a potential diagnostic marker for mucormycosis2016
- Author(s)
  Oinuma K., Sato K., Niki M., Kakeya H. and Kaneko Y.
- Organizer
  2016 International Symposium on New Frontiers in Microbiology and Biotechnology
- Place of Presentation
  筑波大学（茨城県つくば市）
- Year and Date
  2016-07-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26850060
[Presentation] Aspergillus calidoustus重複感染が確認されたLichtheimia ramosaによる消化管型ムーコル症の一例2016
- Author(s)
  水谷哲, 老沼研一, 寺地つね子, 掛屋弘, 金子幸弘
- Organizer
  第60回日本医真菌学会総会・学術集会
- Place of Presentation
  東京都立産業貿易センター台東館（東京都台東区）
- Year and Date
  2016-10-01
- Data Source
  KAKENHI-PROJECT-26850060
[Presentation] アシネトバクター属臨床分離株の薬剤感受性試験と分子疫学解析2016
- Author(s)
  老沼研一, 佐藤佳奈子, 鈴木仁人, 柴山恵吾, 滝沢恵津子, 仁木誠, 中家清隆, 仁木満美子, 山田康一, 掛屋弘, 金子幸弘
- Organizer
  第59回日本感染症学会中日本地方会学術集会
- Place of Presentation
  沖縄コンベンションセンター, カルチャーリゾートフェストーネ（沖縄県宜野湾市）
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-26850060
[Presentation] マウスモデルを用いた侵襲性肺ムーコル症に対する新規診断系の検討2016
- Author(s)
  金子幸弘, 佐藤佳奈子, 老沼研一, 仁木満美子, 山田康一, 山越智, 宮崎義継, 掛屋弘
- Organizer
  第59回日本感染症学会中日本地方会学術集会
- Place of Presentation
  沖縄コンベンションセンター, カルチャーリゾートフェストーネ（沖縄県宜野湾市）
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-26850060
[Presentation] Aspergillus niger由来芳香族ポリエステル分解酵素の発見と解析2015
- Author(s)
  老沼研一、金子達雄、高谷直樹
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山大学津島キャンパス（岡山県岡山市）
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-26850060
[]

1. Kaneko Yukihiro (90469958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. 仁木満美子 (20438229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 掛屋弘 (40398152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. 鈴木仁人 (70444073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. TAKAYA Naoki

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. KANEKO Tatsuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
7. KIZAWA Yoshie

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 吉村満美子

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results

Oinuma Ken-Ichi 老沼 研一

老沼 研一 オイヌマ ケンイチ

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緑膿菌の病原性抑制薬の開発に向けたクオラムセンシング制御機構の基盤研究Principal Investigator

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Molecular epidemiology of drug-resistant Acinetobacter

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Functional analysis of AHL receptors toward comprehensive understanding of the quorum sensing mechanism in Pseudomonas aeruginosaPrincipal Investigator

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Screening and analysis of aromatic polymer-hydrolyzing enzymesPrincipal Investigator

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[Journal Article] Discovery of a LuxR-type regulator involved in isoniazid-dependent gene regulation in Mycobacterium smegmatis2023

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[Journal Article] Identification of a mycobacterial hydrazidase, an isoniazid-hydrolyzing enzyme2023

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[Journal Article] Genome-Based Epidemiological Analysis of 13 <i>Acinetobacter</i> Strains Isolated from Blood Cultures of Hospitalized Patients from a University Hospital in Japan2019

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[Journal Article] The Pseudomonas aeruginosa orphan quorum sensing signal receptor QscR regulates global quorum sensing gene expression by activating a single linked operon2018

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[Journal Article] Successful Treatment of Intestinal Mycosis Caused by a Simultaneous Infection with <i>Lichtheimia ramosa</i> and <i>Aspergillus calidoustus</i>2018

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[Journal Article] Clinical characteristics of bacteremia caused by extended-spectrum beta-lactamase-producing Escherichia coli at a tertiary hospital2017

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[Journal Article] Structural basis of the substrate recognition of hydrazidase isolated from Microbacterium sp. strain HM58-2, which catalyzes acylhydrazide compounds as its sole carbon source2017

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[Journal Article] Alternative fermentation pathway of cinnamic acid production via phenyllactic acid2016

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[Journal Article] An Intrinsic Strain of Colistin-resistant <i>Acinetobacter</i> Isolated from a Japanese Patient2016

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Oinuma Ken-Ichi 老沼研一

老沼研一オイヌマケンイチ