Ikeda Kazuho 池田一穂

Researcher Number	20642565
Affiliation (Current)	2025: 東京大学, 大学院医学系研究科(医学部), 講師
Affiliation (based on the past Project Information) *help	2019 – 2025: 東京大学, 大学院医学系研究科(医学部), 講師 2018 – 2019: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 上級研究員 2017: 国立研究開発法人理化学研究所, 生命システム研究センター, 上級研究員 2015 – 2017: 国立研究開発法人理化学研究所, 生命システム研究センター, 研究員 2013 – 2014: 独立行政法人理化学研究所, 生命システム研究センター, 研究員
Review Section/Research Field	Principal Investigator Cell biology / Basic Section 48010:Anatomy-related Except Principal Investigator Basic Section 48010:Anatomy-related / General anatomy (including histology/embryology) / Mathematical Sciences in Search of New Cooperation
Keywords	Principal Investigator 細胞内物質輸送 / メラノソーム / ゲノム編集 / メラノサイト / メラノソーム輸送 / 黒色素胞細胞 / 蛍光プローブ / 分子モーター / ゲノム編集技術 / キネシン / 黒色素胞 / TALEN … More Except Principal Investigator … More 分子モーター / キネシン / 微小管 / ライブイメージング / RNA / 軸索輸送 / ライブセルイメージング / 一分子計測 / 超解像顕微鏡法 / 一分子イメージング / 微小管内腔結合タンパク質 / 1分子計測 / イメージングプローブ / 細胞生物学 / 液－液相分離 / 小胞輸送 / 分子混雑 / 発生生物学 / 遺伝子発現 / ゆらぎ / 分子進化 / 揺らぎの定理 / １分子計測 / 生物物理 / 医療 / 非平衡統計力学 / 微小管結合タンパク質 / 細胞極性 / 細胞内輸送 Less

細胞質流動性の維持制御機構の探索
- Principal Investigator
  
  岡田康志
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Institute of Physical and Chemical Research
超解像・一分子イメージングによる微小管内腔結合タンパク質の解析
- Principal Investigator
  
  岡田康志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Institute of Physical and Chemical Research
Phase-separation dynamics of pathogenic RNA granules revealed by visualization and manipulation method of endogenous RNA
- Principal Investigator
  
  Takai Akira
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  The University of Tokyo
  Institute of Physical and Chemical Research
Comparison of melanosome transport kinetics to characterize molecular motor intracellular motilityPrincipal Investigator
- Principal Investigator
  
  Ikeda Kazuho
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  The University of Tokyo
Why do vesicles move faster in the axon than in vitro?
- Principal Investigator
  
  Yasushi Okada
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  The University of Tokyo
Development of visualization and manipulation of RNAs based on artificial RNA-binding protein and analysis of sum total RNA
- Principal Investigator
  
  Takai Akira
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Institute of Physical and Chemical Research
The mechanism of switching cytoskeletons in intracellular transport.Principal Investigator
- Principal Investigator
  
  Ikeda Kazuho
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokyo
  Institute of Physical and Chemical Research
Why are there more than 40 kinesins in our genome?
- Principal Investigator
  
  Yasushi Okada
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  The University of Tokyo
Application of theorems of non-equilibrium stochastic models to medical and cosmetic problems
- Principal Investigator
  
  Hayashi Kumiko
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Mathematical Sciences in Search of New Cooperation
- Research Institution
  Tohoku University
Study of regulatory mechanism for intracellular transport using high efficient genome editing mediated by improved TALEN.Principal Investigator
- Principal Investigator
  
  Ikeda Kazuho
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Institute of Physical and Chemical Research
Mechanisms for the navigation of the intracellular transport
- Principal Investigator
  
  Okada Yasushi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Institute of Physical and Chemical Research

All 2024 2023 2022 2020 2019 2018 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] c-Src-mediated phosphorylation and activation of kinesin KIF1C promotes elongation of invadopodia in cancer cells2022
- Author(s)
  Saji Takeshi、Nishita Michiru、Ikeda Kazuho、Endo Mitsuharu、Okada Yasushi、Minami Yasuhiro
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 7 Pages: 102090-102090
- DOI
  10.1016/j.jbc.2022.102090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07575, KAKENHI-PROJECT-21K06748, KAKENHI-PROJECT-21K20641, KAKENHI-PROJECT-23K24060, KAKENHI-ORGANIZER-19H05794, KAKENHI-PLANNED-19H05795
[Journal Article] Investigation of multiple-dynein transport of melanosomes by non-invasive force measurement using fluctuation unit χ2019
- Author(s)
  Hasegawa Shin、Sagawa Takashi、Ikeda Kazuho、Okada Yasushi、Hayashi Kumiko
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 5099-5108
- DOI
  10.1038/s41598-019-41458-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07400, KAKENHI-PROJECT-16H05119, KAKENHI-PROJECT-17H03659, KAKENHI-PROJECT-17K19511
[Journal Article] Engineered Tug-of-War Between Kinesin and Dynein Controls Direction of Microtubule Based Transport In Vivo2016
- Author(s)
  Rezaul K, Gupta D, Semenova I, Ikeda K, Kraikivski P, Yu J, Cowan A, Zaliapin I, Rodionov V.
- Journal Title
  
  Traffic
  
  Volume: 17(5) Issue: 5 Pages: 475-486
- DOI
  10.1111/tra.12385
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440108
[Journal Article] Regulation of microtubule-based transport by MAP4.2014
- Author(s)
  Semenova I, Ikeda K, Resaul K, Kraikivski P, Aguiar M, Gygi S, Zaliapin I, Cowan A, Rodionov V.
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 25 Issue: 20 Pages: 3119-32
- DOI
  10.1091/mbc.e14-01-0022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293046, KAKENHI-PROJECT-26440108
[Presentation] ゲノム構造のライブイメージングのための多階層プローブの開発2024
- Author(s)
  池田一穂
- Organizer
  第129回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-21K06748
[Presentation] ゲノム可視化プローブの開発2023
- Author(s)
  池田一穂、岡田康志
- Organizer
  第128回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-21K06748
[Presentation] ゲノム配列特異的結合プローブの結合動態解析と改良2022
- Author(s)
  池田一穂、岡田康志
- Organizer
  第127回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-21K06748
[Presentation] ゲノム配列認識プローブの一分子解析2020
- Author(s)
  池田一穂
- Organizer
  第125回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-17K07400
[Presentation] TALE蛋白質の新規構築法と応用2018
- Author(s)
  池田一穂、寺原陽子、岡田康志
- Organizer
  第123回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-17K07400
[Presentation] A simple and accurate construction of TALEs and its applications2018
- Author(s)
  K.Ikeda, Y.Terahara, Y.Okada
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-17K07400
[Presentation] A simple and accurate construction of TALEs and its applications2018
- Author(s)
  K.Ikeda, Y.Terahara, Y.Okada
- Organizer
  第70回日本細胞生物学会総会
- Data Source
  KAKENHI-PROJECT-17K07400
[Presentation] Application of the fluctuation theorem to the non-invasive force measurement during the transport of pigment granules in melanocytes2016
- Author(s)
  S. Hasegawa, K. Ikeda, T. Sagawa, Y. Okada, K. Hayashi
- Organizer
  ASCB (American Society for Cel Biology) annual meeting
- Place of Presentation
  サンフランシスコ、アメリカ
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-26310204
[Presentation] ゲノム任意配列可視化のための高活性TALEプローブの開発2016
- Author(s)
  池田一穂、寺原陽子、隅山健太、岡田康志
- Organizer
  第121回日本解剖学会総会・全国学術集会
- Place of Presentation
  ビッグパレットふくしま(郡山市福島県)
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-26440108
[Presentation] In vitro analysis of super-active TALE protein2016
- Author(s)
  Ikeda, K., Terahara, Y., Miyashita, N., and Okada, Y.
- Organizer
  ASCB annual meeting
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2016-12-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440108
[Presentation] ゆらぎの定理を用いた非侵襲な力測定によるメラニン色素顆粒輸送のメカニズムの解明2016
- Author(s)
  長谷川慎, 池田一穂, 佐川貴志, 岡田康志, 林久美子
- Organizer
  第５４回日本生物物理学会年会
- Place of Presentation
  つくば国際会議場（つくば市）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-26310204
[Presentation] Development of super-active TALEs for efficient genome visualizing and manipulating tools2015
- Author(s)
  Kazuho Ikeda, Yoko Terahara, Kenta Sumiyama, Naoyuki Miyashita, and Yasushi Okada
- Organizer
  The International Chemical Congress of Pacific Basin Societies
- Place of Presentation
  Honolulu, HI, USA
- Year and Date
  2015-12-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440108
[Presentation] 高活性TALE蛋白質の開発とゲノム配列ライブイメージングへの応用2015
- Author(s)
  池田一穂、寺原陽子、隅山健太、岡田康志
- Organizer
  第67回日本細胞生物学会大会
- Place of Presentation
  タワーホール船堀(東京都江戸川区)
- Year and Date
  2015-07-02
- Data Source
  KAKENHI-PROJECT-26440108
[Presentation] In vitro analysis of super-active TALE2015
- Author(s)
  Yoko Terahara, Kazuho Ikeda, Kenta Sumiyama, Naoyuki Miyashita, and Yasushi Okada
- Organizer
  ASCB annual meeting
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440108
[Presentation] ゆらぎ計測によるゼブラフィッシュ色素顆粒輸送の力-速度関係2015
- Author(s)
  長谷川慎、池田一穂、岡田康志、林久美子
- Organizer
  第53回日本生物物理学会年会
- Place of Presentation
  金沢大学
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-26310204
[Presentation] Development and application of improved TALE protein2015
- Author(s)
  池田一穂、寺原陽子、隅山健太、岡田康志
- Organizer
  第53回日本生物物理学会年会
- Place of Presentation
  金沢大学(石川県金沢市)
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-26440108
[Presentation] Super-active TALEN with improved stability at 37 degree Celsius enables highly efficient and homogeneous gene knockout in mammalian embryos
- Author(s)
  K. Ikeda, Y. Terahara, K. Sumiyama, N. Miyashita, Y. Sugita, Y. Okada
- Organizer
  The 2014 ASCB/IFCB meeting
- Place of Presentation
  Philadelphia, PA, USA
- Year and Date
  2014-12-06 – 2014-12-10
- Invited
- Data Source
  KAKENHI-PROJECT-26440108
[Presentation] 熱安定型高活性TALENの開発
- Author(s)
  池田一穂、宮下尚之
- Organizer
  バイオスーパーコンピューティング研究会(BSCRC)「ウィンタースクール 2015」
- Place of Presentation
  愛知県田原市中山町
- Year and Date
  2015-01-30 – 2015-01-31
- Invited
- Data Source
  KAKENHI-PROJECT-26440108

1. Okada Yasushi (50272430)

# of Collaborated Projects: 7 results

# of Collaborated Products: 10 results
2. 神原丈敏 (40451637)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. Takai Akira (60637205)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 池崎圭吾 (10722960)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 榎佐和子 (50467635)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. Ito Yoko (60584571)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 丹羽伸介 (30714985)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. Shima Tomohiro (60631786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Hayashi Kumiko (00585979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. 木村暁 (10365447)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 有吉哲郎 (00782103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Li Xue (50936507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NISHITA MICHIRU

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ikeda Kazuho 池田 一穂

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Comparison of melanosome transport kinetics to characterize molecular motor intracellular motilityPrincipal Investigator

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The mechanism of switching cytoskeletons in intracellular transport.Principal Investigator

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Study of regulatory mechanism for intracellular transport using high efficient genome editing mediated by improved TALEN.Principal Investigator

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[Journal Article] c-Src-mediated phosphorylation and activation of kinesin KIF1C promotes elongation of invadopodia in cancer cells2022

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[Journal Article] Investigation of multiple-dynein transport of melanosomes by non-invasive force measurement using fluctuation unit χ2019

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[Journal Article] Engineered Tug-of-War Between Kinesin and Dynein Controls Direction of Microtubule Based Transport In Vivo2016

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[Journal Article] Regulation of microtubule-based transport by MAP4.2014

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Ikeda Kazuho 池田一穂