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Ishihara Mikiya  石原 幹也

ORCIDConnect your ORCID iD *help
Researcher Number 20707369
Other IDs
Affiliation (Current) 2025: 地方独立行政法人大阪府立病院機構大阪国際がんセンター(研究所), その他部局等, 腫瘍内科 副部長
2025: 三重大学, 医学系研究科, リサーチアソシエイト
Affiliation (based on the past Project Information) *help 2023: 三重大学, 医学系研究科, リサーチアソシエイト
2020 – 2022: 三重大学, 医学部附属病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related
Except Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords
Principal Investigator
γδ-T細胞 / 幹細胞様メモリーT細胞 / CAR / 遺伝子改変 / ミトコンドリア機能 / αβ-TCR / γδT細胞
Except Principal Investigator
off-the-shelf / 細胞免疫療法 / 固形がん … More / persistence / CAR-T細胞 / 幹細胞様メモリーT細胞 / 同種γδ-T細胞 Less
  • Research Projects

    (3 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (8 People)
  •  幹細胞様メモリーT細胞分画に優れるγδ-T細胞の誘導法の検討Principal Investigator

    • Principal Investigator
      石原 幹也
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Mie University
  •  Aim to eliminate a bottleneck in the practical realization of anticancer immunotherapy with gene-modified allogeneic gammadelta T cells.

    • Principal Investigator
      藤原 弘
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Mie University
  •  Pursuit of multifunctional gene-modified gamma-delta T cells focusing on energy metabolismPrincipal Investigator

    • Principal Investigator
      Ishihara Mikiya
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Mie University

All 2023 2022 2021

All Journal Article Presentation

  • [Journal Article] Ganglioside GD2 Expression Is Associated With Unfavorable Prognosis in Early Triple-negative Breast Cancer2023

    • Author(s)
      HIGASHI CHIHIRO、SAITO KANAKO、KOZUKA YUJI、YUASA HIROTO、NAKAMURA KAHO、ISHITOBI MAKOTO、ISHIHARA MIKIYA、MIZUNO TOSHIRO、TAWARA ISAO、FUJIWARA HIROSHI、OGAWA TOMOKO
    • Journal Title

      Anticancer Research

      Volume: 43 Issue: 9 Pages: 4045-4053

    • DOI

      10.21873/anticanres.16593

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08593, KAKENHI-PROJECT-18K06988, KAKENHI-PROJECT-23K27455
  • [Journal Article] αβ-T cell receptor transduction gives superior mitochondrial function to γδ-T cells with promising persistence2023

    • Author(s)
      Ishihara Mikiya、Miwa Hiroshi、Fujiwara Hiroshi、Akahori Yasushi、Kato Takuma、Tanaka Yoshimasa、Tawara Isao、Shiku Hiroshi
    • Journal Title

      iScience

      Volume: 26 Issue: 10 Pages: 107802-107802

    • DOI

      10.1016/j.isci.2023.107802

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07228, KAKENHI-PROJECT-23K06714, KAKENHI-PROJECT-23K06740, KAKENHI-PROJECT-23K27455
  • [Presentation] αβ-TCR transduction into γδ-T cells enhances mitochondrial function2023

    • Author(s)
      Mikiya Ishihara, Hiroshi Miwa, Hiroshi Fujiwara, Yasushi Akahori, Takuma Kato, Yoshimasa Tanaka, Isao Tawara and Hiroshi Shiku
    • Organizer
      The 10th International γδ T cell conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K06740
  • [Presentation] NY-ESO-1特異的αβTCR遺伝子導入γδT細胞の機能とエネルギー代謝特性2022

    • Author(s)
      石原 幹也、三輪 啓志、藤原 弘、赤堀 泰、加藤 琢磨、田中 義正、俵 功、珠玖 洋
    • Organizer
      第6回 日本サルコーマ治療研究学会
    • Data Source
      KAKENHI-PROJECT-20K07656
  • [Presentation] Energy metabolism spread to non-glycolysis in αβ-TCR transduced γδ-T cells2022

    • Author(s)
      石原 幹也、三輪 啓志、藤原 弘、赤堀 泰、加藤 琢磨、田中 義正、俵 功、珠玖 洋
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K07656
  • [Presentation] NY-ESO-1特異的αβTCR遺伝子導入γδT細胞のエネルギー代謝2022

    • Author(s)
      石原 幹也、三輪 啓志、藤原 弘、赤堀 泰、加藤 琢磨、田中 義正、俵 功、珠玖 洋
    • Organizer
      第26回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20K07656
  • [Presentation] Function and metabolism of NY-ESO-1-specific γδ TCR transduced Vδ2+ cells2021

    • Author(s)
      Mikiya Ishihara,Hiroshi Miwa, Yasushi Akahori, Hiroshi Fujiwara, Takuma Kato, Yoshimasa Tanaka, Isao Tawara and Hiroshi Shiku
    • Organizer
      第80回日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-20K07656
  • 1.  三輪 啓志 (00209967)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 2.  藤原 弘 (20398291)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 3.  赤堀 泰 (80221711)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  瀬尾 尚宏 (50283354)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  加藤 琢磨 (60224515)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  SAITO Kanako
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  小塚 祐司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  小川 朋子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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