Hasegawa Natsumi 長谷川菜摘

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HASEGAWA Natsumi 長谷川菜摘

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Researcher Number	20708599
Other IDs
Affiliation (Current)	2025: 神戸大学, 保健学研究科, 助教
Affiliation (based on the past Project Information) *help	2013 – 2023: 神戸大学, 保健学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 52010:General internal medicine-related / Laboratory medicine
Keywords	Principal Investigator MED1 / 乳癌 / 転写メディエーター / ERα / エストロゲン受容体 / エストロゲン受容体α / 転写コアクチベーター / MED１ / ホルモン依存性癌 / 発癌 / メディエーター転写共役複合体 / 転写因子

基本的転写共役因子MED1が統合する乳癌増殖機構と介入の可能性Principal Investigator
- Principal Investigator
  
  長谷川菜摘
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kobe University
Hormone-dependent cancer and the transcriptional coactivator MED1Principal Investigator
- Principal Investigator
  
  HASEGAWA NATSUMI
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kobe University
The role for Mediator subunits MED1 in the property of breast carcinomasPrincipal Investigator
- Principal Investigator
  
  Hasegawa Natsumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kobe University
The role for Mediator transcriptional coregulator complex in the property of breast carcinomasPrincipal Investigator
- Principal Investigator
  
  HASEGAWA Natsumi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Laboratory medicine
- Research Institution
  Kobe University

All 2020 2019 2016 2015 2014 2013

All Journal Article Presentation

[Journal Article] Matrix Gla protein maintains normal and malignant hematopoietic progenitor cells by interacting with bone morphogenetic protein-42020
- Author(s)
  Kana Kuronuma, Aya Yokoi, Tomoya Fukuoka, Muneaki Miyata, Akio Maekawa, Satowa Tanaka, Leo Matsubara, Chie Goto, Miki Matsuo, Hao-Wei Han, Mai Tsuruta, Haruka Murata, Hikari Okamoto, Natsumi Hasegawa, Shigetaka Asano, Mitsuhiro Ito
- Journal Title
  
  Heliyon
  
  Volume: 6 Issue: 4 Pages: 03743-03743
- DOI
  10.1016/j.heliyon.2020.e03743
- NAID
  120006844969
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09012, KAKENHI-PROJECT-20K07782, KAKENHI-PROJECT-18K15418
[Journal Article] PML-RARα Induces All-Trans Retinoic Acid-Dependent Transcriptional Activation Through Interaction With MED12019
- Author(s)
  Tomoya Fukuoka, Asami Kawai, Taku Takahara, Mahiro Mori, Robert G Roeder, Natsumi Hasegawa, Mitsuhiro Ito
- Journal Title
  
  Transcription
  
  Volume: 10 Issue: 3 Pages: 147-156
- DOI
  10.1080/21541264.2019.1624467
- NAID
  120006653243
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15418, KAKENHI-PROJECT-17K09012
[Journal Article] Translin restricts the growth of pubertal mammary epithelial cells estrogen-independently in mice.2019
- Author(s)
  Matsubara L, Fukuoka T, Sudo K, Fukunaga T, Imanishi A, Kuronuma K, Matsuo M, Kamoshida S, Hasegawa N, Asano S, Ito M.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 521 Issue: 3 Pages: 562-568
- DOI
  10.1016/j.bbrc.2019.10.176
- NAID
  120006784500
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15418, KAKENHI-PROJECT-17K09012, KAKENHI-PROJECT-20K07782
[Journal Article] CCAR1/CoCoA pair-mediated recruitment of the Mediator defines a novel pathway for GATA1 function.2014
- Author(s)
  Mizuta S, Minami T, Fujita H, Kaminaga C, Matsui K, Ishino R, Fujita A, Oda K, Kawai A, Hasegawa N, Urahama N, Roeder RG, Ito M
- Journal Title
  
  Genes to cells
  
  Volume: 19 Issue: 1 Pages: 28-51
- DOI
  10.1111/gtc.12104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J03621, KAKENHI-PROJECT-23591388, KAKENHI-PROJECT-23790623, KAKENHI-PROJECT-25893130, KAKENHI-PROJECT-26460677
[Journal Article] Mediator subunit MED1 is a T3-dependent and T3-independent coactivator on the thyrotropin β gene promoter.2013
- Author(s)
  Matsui K. Oda K, Mizuta S, Ishino R, Urahama N, Hasegawa N, Roeder RG, Ito M
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 440 Issue: 1 Pages: 184-189
- DOI
  10.1016/j.bbrc.2013.09.061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J03621, KAKENHI-PROJECT-23591388, KAKENHI-PROJECT-23790623, KAKENHI-PROJECT-25893130
[Journal Article] FGF7 supports hematopoietic stem and progenitor cells and niche-dependent myeloblastoma cells via autocrine action on bone marrow stromal cells in vitro.2013
- Author(s)
  Ishino R, Minami K, Tanaka S, Nagai M, Matsui K, Hasegawa N, Roeder RG, Asano S, Ito M
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 440 Issue: 1 Pages: 125-131
- DOI
  10.1016/j.bbrc.2013.09.044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J03621, KAKENHI-PROJECT-23591388, KAKENHI-PROJECT-25893130
[Presentation] MGP supports niche-dependent myeloid leukemic cells in a Glu γ-carboxylation independent manner.2019
- Author(s)
  Haruka Murata，Kana Kuronuma，Leo Matsubara，Aya Yokoi， Hikari Okamoto，Mai Tsuruta，Tomoya Fukuoka，Miki Matsuo, Natsumi Hasegawa，Shigetaka Asano，Mitsuhiro Ito.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15418
[Presentation] ATRA dependent interaction of MED1 with oncofusion protein PML-RARα initiates transcriptional activation.2019
- Author(s)
  Tomoya Fukuoka, Miki Matsuo, Hikaru Tsutsumi, Rino Kishida, Manami Tsuji, Mana Morikawa, Mizuha Anamoto, Naoya Kanada, Kyo Saiki, Robert G. Roeder, Natsumi Hasegawa, Mitsuhiro Ito.
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K15418
[Presentation] Translin modulates mesenchymal cell proliferation and differentiation in mice.2019
- Author(s)
  Kana Kuronuma, Yukiko Ikeuchi, Azusa Imanishi, Katsuko Sudo, Takako Fukunaga, Leo Matsubara, Aya Yokoi, Chie Goto, Tomoya Fukuoka, Miki Matsuo, Ruri Kono, Natsumi Hasegawa, Shigetaka Asano, Mitsuhiro Ito.
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K15418
[Presentation] The interaction of PML-RARα with MED1 initiates ATRA dependent transcriptional activation.2019
- Author(s)
  Tomoya Fukuoka，Miki Matsuo，Hikaru Tsutsumi，Mana Morikawa， Rino Kishida，Manami Tsuji，Kyo Saiki，Naoya Kanada， Mizuha Anamoto，Natsumi Hasegawa，Mitsuhiro Ito.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15418
[Presentation] Matrix Gla protein is a niche factor that supports myeloid leukemic cells without Glu γ-carboxylation.2019
- Author(s)
  Mai Tsuruta, Kana Kuronuma, Leo Matsubara, Haruka Murata, Hikari Okamoto, Hao-Wei Han, Tomoya Fukuoka, Miki Matsuo, Shun Ito, Natsumi Hasegawa, Shigetaka Asano, Mitsuhiro Ito.
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K15418
[Presentation] MED1-dependent and -independent coactivation mechanism of Mediator for GATA1 action2016
- Author(s)
  森　真洋,長谷川　菜摘,伊藤　光宏
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K19180
[Presentation] The role of MED1 in breast carcinogenesis and progression2016
- Author(s)
  峰松　有希,長谷川　菜摘,伊藤　光宏
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K19180
[Presentation] Periostin supports hematopoietic stem/progenitor cells and niche-dependent myeloblastoma cells in vitro2016
- Author(s)
  前川　晶保,長谷川　菜摘,伊藤　光宏
- Organizer
  58th ASH Annual Meeting and Exposition
- Place of Presentation
  San Diego Convention Center
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-15K19180
[Presentation] RAR-binding ability of MED1 is required for high-concentrationATRA-dependent activation of PML-RARα2016
- Author(s)
  高原　拓,長谷川　菜摘,伊藤　光宏
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-15K19180
[Presentation] High-concentration ATRA-dependent activation of PML-RARα requires Mediator subunit MED1.2015
- Author(s)
  Asami Kawai, Natsumi Hasegawa, Mitsuhiro Ito
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K19180
[Presentation] Mediator subunit MED1 is required for PML-RARα fusion protein-induced transcriptional activation in response high concentration all-trans retinoic acid.2015
- Author(s)
  Taku Takahara, Asami Kawai, Mahiro Mori, Gentaro Tango, Yusuke Takemoto, Akane Maekawa, Norinaga Urahama, Natsumi Hasegawa, Mitsuhiro Ito
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K19180
[Presentation] 乳癌発症が遺伝要因と環境要因に依存する可能性ー乳癌モデルマウスの検討2015
- Author(s)
  井之上菜名子、長谷川菜摘、神田織江、峰松侑希、武元優允、丹後元太郎、前川茜、長崎洋樹、今西梓、伊藤光宏
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K19180
[Presentation] 乳癌発症が遺伝要因と環境要因に依存する可能性−乳癌モデルマウスの検討2015
- Author(s)
  武元優允、松井啓治、前川茜、長崎洋樹、井之上菜名子、物延沙耶、長谷川菜摘、Robert G. Roeder、伊藤光宏
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K19180

1. ITO Mitsuhiro (50362794)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results

Hasegawa Natsumi 長谷川 菜摘

HASEGAWA Natsumi 長谷川 菜摘

Research Projects

Research Products

Co-Researchers

基本的転写共役因子MED1が統合する乳癌増殖機構と介入の可能性Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Hormone-dependent cancer and the transcriptional coactivator MED1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role for Mediator subunits MED1 in the property of breast carcinomasPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role for Mediator transcriptional coregulator complex in the property of breast carcinomasPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Matrix Gla protein maintains normal and malignant hematopoietic progenitor cells by interacting with bone morphogenetic protein-42020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] PML-RARα Induces All-Trans Retinoic Acid-Dependent Transcriptional Activation Through Interaction With MED12019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Translin restricts the growth of pubertal mammary epithelial cells estrogen-independently in mice.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] CCAR1/CoCoA pair-mediated recruitment of the Mediator defines a novel pathway for GATA1 function.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mediator subunit MED1 is a T3-dependent and T3-independent coactivator on the thyrotropin β gene promoter.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] FGF7 supports hematopoietic stem and progenitor cells and niche-dependent myeloblastoma cells via autocrine action on bone marrow stromal cells in vitro.2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] MGP supports niche-dependent myeloid leukemic cells in a Glu γ-carboxylation independent manner.2019

Author(s)

Organizer

Data Source

[Presentation] ATRA dependent interaction of MED1 with oncofusion protein PML-RARα initiates transcriptional activation.2019

Author(s)

Organizer

Data Source

[Presentation] Translin modulates mesenchymal cell proliferation and differentiation in mice.2019

Author(s)

Organizer

Data Source

[Presentation] The interaction of PML-RARα with MED1 initiates ATRA dependent transcriptional activation.2019

Author(s)

Organizer

Data Source

[Presentation] Matrix Gla protein is a niche factor that supports myeloid leukemic cells without Glu γ-carboxylation.2019

Author(s)

Hasegawa Natsumi 長谷川菜摘

HASEGAWA Natsumi 長谷川菜摘

[Presentation] 乳癌発症が遺伝要因と環境要因に依存する可能性−乳癌モデルマウスの検討2015