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Tomohiro TANAKA)  田中 智博

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Tanaka Tomohiro  田中 智博

TANAKA tomohiro  田中 智博

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Researcher Number 20711667
Other IDs
Affiliation (Current) 2025: 岡山大学, 医歯薬学域, 准教授
Affiliation (based on the past Project Information) *help 2025: 岡山大学, 医歯薬学域, 准教授
2022: 岡山大学, 医歯薬学域, 准教授
2020 – 2021: 東京理科大学, 薬学部生命創薬科学科, 助教
2016 – 2017: 公益財団法人野口研究所, 研究部, 研究員
2013 – 2014: 東京理科大学, 薬学部, ポストドクトラル研究員
Review Section/Research Field
Principal Investigator
Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Basic Section 37030:Chemical biology-related / Drug development chemistry / Chemical pharmacy
Keywords
Principal Investigator
ホウ素クラスター / メディシナルケミストリー / 亜鉛錯体 / グルコーストランスポータ / ホウ素中性子線補足療法 / カチオン性ポリマー / キャリア分子 / BSH / ホウ素中性子線捕捉療法 / 銅イオン検出 … More / 薬学 / 銅(II)イオン / カルボラン / ホウ素MRI / キラル分子 / 酵素反応 / チオール / リン酸化酵素 / 水溶性 / バイオミメティック / ロタキサン / 分子機械 Less
  • Research Projects

    (4 results)
  • Research Products

    (41 results)
  • Co-Researchers

    (4 People)
  •  静電的相互作用に基づくがん標的中分子キャリアの創出と次世代放射線療法への応用Principal Investigator

    • Principal Investigator
      田中 智博
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
    • Research Institution
      Okayama University
  •  Development of carrier molecule targeted GLUTPrincipal Investigator

    • Principal Investigator
      Tanaka Tomohiro
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 37030:Chemical biology-related
    • Research Institution
      Okayama University
      Tokyo University of Science
  •  Development of signal amplification probes for detection of Copper (II) ions Using 11B NMR/MRIPrincipal Investigator

    • Principal Investigator
      Tanaka Tomohiro
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Drug development chemistry
    • Research Institution
      The Noguchi Institute
  •  Design and Synthesis of Helical Moving Rotaxane Molecules Having Chiral AxisPrincipal Investigator

    • Principal Investigator
      TANAKA tomohiro
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Chemical pharmacy
    • Research Institution
      Tokyo University of Science

All 2023 2022 2021 2020 2017 2016 2014 Other

All Journal Article Presentation Patent

  • [Journal Article] Effect of N-Benzyl Group in Indole Scaffold of Thiosemicarbazones on the Biological Activity of Their Pd(II) Complexes: DFT, Biomolecular Interaction, in Silico Docking, ADME and Cytotoxicity Studies2022

    • Author(s)
      Nithya Balakrishnan, Jebiti Haribabu, Rahime Eshaghimalekshah, Srividya Swaminathan, Chandrasekar Balachandran, Nattamai S.P. Bhuvanesh, Shin Aoki, Ramasamy Karvembu,
    • Journal Title

      Inorganica Chimica Acta

      Volume: 534 Issue: 5

    • DOI

      10.1002/ejic.202100949

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K05712, KAKENHI-PROJECT-20K05755
  • [Journal Article] Development of Metallosupramolecular Phosphatases Based on Combinatorial Self-Assembly of Metal Complexes and Organic Building Blocks for Catalytic Hydrolysis of Phosphate Monoesters2021

    • Author(s)
      S. Aoki, A. B. Rahman, Y. Hisamatsu, Y. Miyazawa, M. Zulkefeli, Y. Saga, and Tomohiro Tanaka
    • Journal Title

      Results in Chemistry (a joint special issue with Inorganica Chimica Acta)

      Volume: 3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Journal Article] Isohamnetin Promotes 53BP1 Recruitment through the Enhancement of ATM Phosphorylation and Protects Mice from Radiation Gastrointestinal Syndrome2021

    • Author(s)
      Yuichi Nishiyama, Akinori Morita, Shogo Tatsuta, Misaki Kanamaru, Masahiro Sakaue, Kenta Ueda, Manami Shono, Rie Fujita, Bing Wang, Yoshio Hosoi, Shin Aoki and Takeshi Sugai
    • Journal Title

      Genes

      Volume: 12 Issue: 12 Pages: 8523-8544

    • DOI

      10.1021/acs.jmedchem.1c00445

    • Data Source
      KAKENHI-PROJECT-20K05712, KAKENHI-PROJECT-20K05755
  • [Journal Article] Potential Anti-COVID-19 Agents, Cepharanthine and Nelfinavir, and Their Usage for Combination Treatment2021

    • Author(s)
      H. Ohashi, K. Watashi, W. Saso, K. Shionoya, et al.
    • Journal Title

      iScience

      Volume: 24 Issue: 4 Pages: 335-337

    • DOI

      10.1016/j.isci.2021.102367

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K05712, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PROJECT-19J12155, KAKENHI-ORGANIZER-16H06429, KAKENHI-PROJECT-19J21455, KAKENHI-PROJECT-18K07055, KAKENHI-PROJECT-20K05755, KAKENHI-PROJECT-20K16267, KAKENHI-PROJECT-23K21721
  • [Journal Article] Potential Anti-COVID-19 Agents, Cepharanthine and Nelfinavir, and Their Usage for Combination Treatment2021

    • Author(s)
      H. Ohashi, K. Watashi, T. Tanaka, S. Aoki 他26名
    • Journal Title

      iScience

      Volume: 24

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Journal Article] Crystal structures of fukutin-related protein (FKRP), a ribitol-phosphate transferase related to muscular dystrophy.2020

    • Author(s)
      N. Kuwabara, R. Imae, H. Manya, T. Tanaka, M. Mizuno, H. Tsumoto, M. Kanagawa, K. Kobayashi, T. Toda, T. Senda, T. Endo & R. Kato
    • Journal Title

      NAT COMMUN

      Volume: 11

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Journal Article] Bivalent 14-mer Peptide Ligands of CXCR4 with Polyproline Linkers with Anti-Chemotactic Activity against Jurkat Cells2017

    • Author(s)
      Tomohiro Tanaka, Toru Aoki, Wataru Nomura, Hirokazu Tamamura
    • Journal Title

      J. Pept. Sci.

      Volume: 印刷中 Issue: 7-8 Pages: 574-580

    • DOI

      10.1002/psc.2946

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01420, KAKENHI-PROJECT-16K01931, KAKENHI-PROJECT-16K18915, KAKENHI-PROJECT-15H04652, KAKENHI-PROJECT-16K15139
  • [Journal Article] Concise and Versatile Synthesis of Sulfoquinovosyl Acyl Glycerol Derivatives for Biological Applications2017

    • Author(s)
      Tomohiro Tanaka, Yasuhiro Sawamoto, and Shin Aoki
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 65 Issue: 6 Pages: 566-572

    • DOI

      10.1248/cpb.c17-00135

    • NAID

      130005686027

    • ISSN
      0009-2363, 1347-5223
    • Language
      English
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08225, KAKENHI-PROJECT-16K18915
  • [Journal Article] 11B NMR Probes of Copper(II): Finding and Implications of the Cu2+-Promoted Decomposition of ortho-Carborane Deriviatives.2016

    • Author(s)
      Tomohiro Tanaka, Yukiko Nishiura, Rikita Araki, Takaomi Saido, Ryo Abe and Shin Aoki,
    • Journal Title

      European Journal of Inorganic Chemistry,

      Volume: 2016 Issue: 12 Pages: 1819-1834

    • DOI

      10.1002/ejic.201600117

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460156, KAKENHI-PROJECT-16K18915
  • [Journal Article] 11B NMR/MRI Sensing of Copper(II) Ions In Vitro by the Decomposition of a Hybrid Compound of a nido-o-Carborane and a Metal Chelator2016

    • Author(s)
      omohiro Tanaka, Rikita Araki, Takaomi Saido, Ryo Abe, and Shin Aoki
    • Journal Title

      European Journal of Inorganic Chemistry

      Volume: - Issue: 20 Pages: 3330-3337

    • DOI

      10.1002/ejic.201600346

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460156, KAKENHI-PROJECT-16K18915
  • [Patent] 抗SARS-CoV-2薬2021

    • Inventor(s)
      馬場昌範、岡本美佳、外山政明、青木伸、田中智博、横井健汰
    • Industrial Property Rights Holder
      馬場昌範、岡本美佳、外山政明、青木伸、田中智博、横井健汰
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] ホウ素中性子線捕捉療法のための BSH/CPナノ粒子の開発2023

    • Author(s)
      田中智博、上田大貴、鈴木実、櫻井良憲、上田真史、青木伸
    • Organizer
      日本薬学会第143回年会
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] 抗マラリア薬アモジアキンをリード化合物とした抗SARS-CoV-2治療薬の創製2022

    • Author(s)
      田中智博、横井健汰、佐藤秀哉、森田都望恵、岡本実佳、外山政明、馬場昌範、青木伸
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] Development of Nanoparticle Composed of BSH and Cationic Polymer for Boron Neutron Capture Therapy (BNCT)2022

    • Author(s)
      Tomohiro Tanaka
    • Organizer
      icpac kota kinabalu 2022
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] Development of Boron-containing Macrocyclic Polyamines and Their Zn(Ⅱ) Complexes for Boron Neutron Capture Therapy2021

    • Author(s)
      上田大貴 、田中智博 、鈴木実 、青木伸
    • Organizer
      錯体化学会第71回討論会
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] 選択的セロトニン再取り込み阻害薬SSRIの抗炎症効果の解明2021

    • Author(s)
      竹中洋平、北畠和己、田中智博、青木伸、月本光俊
    • Organizer
      第65回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] Development of Nanoparticle Composed of BSH and Cationic Polymer for Boron Neutron Capture Therapy (BNCT)2021

    • Author(s)
      Tomohiro Tanaka, Hiroki Ueda, Shin Aoki, Minoru Suzuki, Yoshinori Sakurai
    • Organizer
      13th AFMC International Medicinal Chemistry Symposium (AIMECS 2021)
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] Development of Light-driven Molecular Machines that Perform Unidirectional Motion2021

    • Author(s)
      Ryota Shibauchi, Ong Yong Liang, Mohd Zulkefeli, Tomohiro Tanaka, Shin Aoki
    • Organizer
      2020/2021 International Chemical Congress of Pacific Basin Societies (PACICHEM2020/2021)
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] Development of Boron-containing Macrocyclic Polyamine Derivatives for Boron Neutron Capture Therapy2021

    • Author(s)
      Hiroki Ueda, Taiki Itoh, Kosuke Mizuno, Tomohiro Tanaka, Minoru Suzuki, Yoshinori Sakurai, and Shin Aoki
    • Organizer
      2020/2021 International Chemical Congress of Pacific Basin Societies (PACICHEM2020/2021)
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] Design, Synthesis, and BNCT (Boron Neutron Capture Therapy) Activity of Boron-Containing Macrocyclic Polyamines2021

    • Author(s)
      Hiroki Ueda, Minoru Suzuki, Tomohiro Tanaka, Shin Aoki
    • Organizer
      13th AFMC International Medicinal Chemistry Symposium (AIMECS 2021)
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] 情報科学及び機械工学と連携した抗SARS-CoV-2治療薬の設計及び合成2021

    • Author(s)
      内山 遥、田中 智博、大橋 啓史、塩野谷 果歩、渡士 幸一、倉持 幸司、秋本 康平、竹村 裕、岡本 実佳、外山 政明、馬場 昌範、青木 伸
    • Organizer
      第65回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] Design and Synthesis of Poly(2,2’-bipyridyl) Ligands Directed toward Chelation Therapy of Cancer2021

    • Author(s)
      Masumi Hirose, Zhu Jun Jie, Chandrasekar Balacahndran, Tomohiro Tanaka, Yosuke Hisamatsu, Yasuyuki Yamada, Shin Aoki
    • Organizer
      International Research Network Initiative (IRNI) and 8th International Postgraduate Conference on Pharmaceutical Sciences 2021 (iPoPS2021)
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] Design, Synthesis, and Antiviral Activity of Anti-SARS-CoV-2 Agents in Interdisciplinary Research2021

    • Author(s)
      Haruka Uchiyama, Mayuka Nii, Tomohiro Tanaka, Kohei Akimoto, Hiroshi Takemura, Kaho Shionoya, Hirofumi Ohashi, Koichi Watashi, and Shin Aoki
    • Organizer
      2020/2021 International Chemical Congress of Pacific Basin Societies (PACICHEM2020/2021)
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] Mefloquine Has a Potent Antiviral Activity against Severe Acute Respiratory Syndrome Related Coronavirus 22021

    • Author(s)
      Kaho Shionoya, Masako Yamasaki, Shoya Iwanami, Yusuke Ito, Shuetsu Fukushi, Hirofumi Ohashi, Wakana Saso, Tomohiro Tanaka, Shin Aoki, Kouji Kuramochi, Shingo Iwami, Yoshimasa Takahashi, Tadaki Suzuki, Masamichi Muramatsu, Makoto Takeda, Takaji Wakita and Koichi Watashi
    • Organizer
      第68回日本ウイルス学会学術学会
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] ホウ素中性子捕捉療法のための新規ポリアミン誘導体の開発2021

    • Author(s)
      上田大貴 、田中智博 、鈴木実 、青木伸
    • Organizer
      第30回金属の関与する生体関連反応シンポジウム
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] Development of Nanoparticle Composed of BSH and Cationic Polymer for Boron Neutron Capture Therapy (BNCT)2021

    • Author(s)
      Tomohiro Tanaka, Hiroki Ueda, Shin Aoki, Minoru Suzuki, Yoshinori Sakurai
    • Organizer
      2020/2021 International Chemical Congress of Pacific Basin Societies (PACICHEM2020/2021)
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] cis型アゾベンゼンを含むキラル大環状化合物の合成と異性化反応の検討2021

    • Author(s)
      芝内涼太、田中智博、青木伸
    • Organizer
      第65回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] ホウ素中性子捕捉療法のための新規ポリアミン誘導体の開発2021

    • Author(s)
      〇上田大貴 1、田中智博 1、鈴木実 2、櫻井良憲 2、青木伸 1,3(1東京理大薬、2京大複合研、 3東京理大総合研究院)
    • Organizer
      日本薬学会第141回年会
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] カチオン性ポリマーを用いたホウ素中性子線捕捉療法のためのBSH含有ナノ粒子の開発2021

    • Author(s)
      〇田中智博 1、上田大貴 1、鈴木実 2、櫻井良憲 2、青木伸 1,3(1東京理大薬、2京大複合研、 3東京理大総合研究院)
    • Organizer
      日本薬学会第141回年会
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] Design, Synthesis, and Anti-SARS-CoV-2 Activity of Amodiaquine Analogs2021

    • Author(s)
      Tomoe Morita, Tomohiro Tanaka, Kenta Yokoi, Hidetoshi Sato, Mika Okamoto, Masaaki Toyama, Masanori Baba, and Shin Aoki
    • Organizer
      2020/2021 International Chemical Congress of Pacific Basin Societies (PACICHEM2020/2021)
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] ホウ素中性子捕捉療法を指向したBSH含有ナノ粒子の開発2020

    • Author(s)
      〇田中智博 1、上田大貴 1、鈴木実 2、櫻井良憲 2、青木伸 1,3(1東京理大薬、2京大複合研、 3東京理大総合研究院)
    • Organizer
      京都大学複合原子力科学研究所 第55回学術講演会
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] ホウ素中性子捕捉療法のためのポリアミン誘導体の創製2020

    • Author(s)
      〇上田大貴 1、田中智博 1、鈴木実 2、櫻井良憲 2、青木伸 1,3(1東京理大薬、2京大複合研、 3東京理大総合研究院)
    • Organizer
      京都大学複合原子力科学研究所 第55回学術講演会
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] BNCT 用ポリアミン誘導体の設計・合成および生物学的評価2020

    • Author(s)
      〇上田大貴 1、田中智博 1、鈴木実 2、櫻井良憲 2、青木伸 1,3(1東京理大薬、2京大複合研、 3東京理大総合研究院)
    • Organizer
      第64回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] ホウ素中性子線捕捉療法のための BSH 含有ナノ粒子の創製2020

    • Author(s)
      〇田中智博 1、上田大貴 1、鈴木実 2、櫻井良憲 2、青木伸 1,3(1東京理大薬、2京大複合研、 3東京理大総合研究院)
    • Organizer
      第64回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-20K05755
  • [Presentation] 糖水酸基をBoc基で保護した糖アミノ酸を用いた糖ペプチドの効率的合成法の開発2017

    • Author(s)
      田中智博、杉原礼子、白石美香、松田昭生、水野真盛
    • Organizer
      第36回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-16K18915
  • [Presentation] Synthesis of Glycopeptide Using Boc Group For the Protection of Carbohydrate Hydroxyl Groups2017

    • Author(s)
      田中智博、杉原礼子、白石美香、松田昭生、水野真盛
    • Organizer
      第54回ペプチド討論会
    • Data Source
      KAKENHI-PROJECT-16K18915
  • [Presentation] カルボラン分解反応を利用した銅 (II) イオン検出のための 11 B NMR/MRI プローブの 設計と合成2016

    • Author(s)
      田中 智博、西浦由希子、田村佳、荒木力太、西道隆臣、安部良、青木伸
    • Organizer
      反応と合成の進歩シンポジウム
    • Place of Presentation
      静岡
    • Year and Date
      2016-11-07
    • Data Source
      KAKENHI-PROJECT-16K18915
  • [Presentation] りん酸化を駆動力として構造が変化する分子シャトルの設計と合成2014

    • Author(s)
      2) 大田麻人、田中智博、久松洋介、青木伸、、2014年3月 (予定)
    • Organizer
      日本薬学会第134年
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-25893259
  • [Presentation] 金属イオンによる o-carborane 骨格分解反応の発見と応

    • Author(s)
      田中智博、西浦由希子、久松洋介、荒木力太、西道高臣、安部良、青木伸
    • Organizer
      薬学会第135回年会
    • Place of Presentation
      神戸学院大学(兵庫県)
    • Year and Date
      2015-03-25 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-25893259
  • [Presentation] シクロデキストリン及び亜鉛錯体を有するロタキサンの設計と合成

    • Author(s)
      大田麻人、田中智博、久松洋介、青木伸
    • Organizer
      第57回日本薬学会関東支部大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25893259
  • [Presentation] 放射線増感剤 Sulfoquinovosyl acylglycerol (SQAG) およびその 誘導体の新合成 ルート と放射線増感作用機構の解

    • Author(s)
      澤本 泰宏、田中 智博、久保田 昭、前田 彩、梅澤 雅和、久松 洋介、玉井 郁巳、坂口 謙吾、青木 伸
    • Organizer
      薬学会第135回年会
    • Place of Presentation
      デザインクリエイティブセンター神戸(兵庫県)
    • Year and Date
      2015-03-25 – 2015-03-28
    • Data Source
      KAKENHI-PROJECT-25893259
  • 1.  NOMURA Wataru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  安部 良
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 3.  西道 隆臣
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 4.  青木 伸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results

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