NAGASHIMA Daichi 長嶋大地

… Alternative Names

Nagashima Daichi 長嶋大地

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Researcher Number	20713720
Other IDs
Affiliation (Current)	2025: 横浜薬科大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 横浜薬科大学, 薬学部, 講師 2020 – 2022: 横浜薬科大学, 薬学部, 助教 2017 – 2018: 昭和大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 38050:Food sciences-related / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Hygiene and public health Except Principal Investigator Basic Section 59040:Nutrition science and health science-related
Keywords	Principal Investigator 神経毒性 / アクリルアミド / NMN / ニコチンアミドモノヌクレオチド / MAPK / 酸化ストレス / α-リポ酸 / プロテオミクス / プロテオーム解析 Except Principal Investigator 卵巣摘出 … More / 発達障害 / マイクロダイアリシス / 不安様行動 / 社会性行動 / OVX / ラクトフェリン Less

神経軸索損傷モデルに対するニコチンアミドモノヌクレオチドの新規薬理作用の探索Principal Investigator
- Principal Investigator
  
  長嶋大地
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Yokohama College of Pharmacy
雌性モデルマウスを用いた発達障害様行動に対するラクトフェリンの効果
- Principal Investigator
  
  出雲信夫
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Yokohama College of Pharmacy
acrylamide誘発神経毒性に対するα-リポ酸の有効性の検討Principal Investigator
- Principal Investigator
  
  長嶋大地
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Yokohama College of Pharmacy
Elucidation of expression mechanism of acrylamide-induce neurotoxicity, and development of therapeutic effects by vitamin B1.Principal Investigator
- Principal Investigator
  
  Nagashima Daichi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Hygiene and public health
- Research Institution
  Showa University

All 2024 2023 2022 2021 2019 2018 2017

All Journal Article Presentation

[Journal Article] Nicotinamide Mononucleotide (NMN) Enhances Neurite Outgrowth Comparable to Nerve Growth Factor (NGF) in PC12 Cells2022
- Author(s)
  Daichi Nagashima、Akane Nakagawa、Chisa Matsubara、Noa Mizukami、Megumi Frukawa、Yasuo Watanabe、Nobuo Izumo
- Journal Title
  
  Pharmacometrics
  
  Volume: 102 Pages: 63-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K18909
[Journal Article] Effect of Coriander on H2O2-induced Oxidative Stress in PC12 Cells2022
- Author(s)
  Daichi Nagashima、Chisa Matsubara、Noa Mizukami、Akane Nakagawa、Megumi Furukawa、Masahiro Toho、Ryoken Aoki、Yasuo Watanabe、Nobuo Izumo
- Journal Title
  
  Journal of Clinical and Medical Research
  
  Volume: 4 Pages: 1-10
- DOI
  10.37191/mapsci-2582-4333-4(3)-115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18909
[Journal Article] Acrylamide reduced neurite outgrowth by suppressing p44/42 expression levels in PC12 cells2022
- Author(s)
  Nagashima Daichi、Izumo Nobuo、Yamauchi Takenori、Okubo Shigeko、Yamano Yuko
- Journal Title
  
  Safety and Health at Work
  
  Volume: 13 Pages: S160-S160
- DOI
  10.1016/j.shaw.2021.12.1251
- Data Source
  KAKENHI-PROJECT-20K18909
[Journal Article] Human Recombinant Lactoferrin Promotes Differentiation and Calcification on MC3T3-E1 Cells2022
- Author(s)
  Nagashima Daichi、Ishibashi Yukiko、Kawaguchi Sachiko、Furukawa Megumi、Toho Masahiro、Ohno Megumi、Nitto Takeaki、Izumo Nobuo
- Journal Title
  
  Pharmaceutics
  
  Volume: 15 Issue: 1 Pages: 60-60
- DOI
  10.3390/pharmaceutics15010060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18909
[Journal Article] Quantification of bromide ion in biological samples using headspace gas chromatography-mass spectrometry2021
- Author(s)
  Yamauchi Takenori、Nagashima Daichi、Okubo Shigeko、Kokaze Akatsuki、Yamano Yuko
- Journal Title
  
  Journal of Occupational Health
  
  Volume: 63 Issue: 1 Pages: n/a
- DOI
  10.1002/1348-9585.12274
- NAID
  130008120338
- ISSN
  1341-9145, 1348-9585
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18909
[Journal Article] Zinc-containing Mohs’ paste affects blood flow and angiogenesis suppression2021
- Author(s)
  Nagashima Daichi、Furukawa Megumi、Yamano Yuko、Yamauchi Takenori、Okubo Shigeko、Toho Masahiro、Ito Yoshihisa、Izumo Nobuo
- Journal Title
  
  DARU Journal of Pharmaceutical Sciences
  
  Volume: 29 Issue: 2 Pages: 321-328
- DOI
  10.1007/s40199-021-00409-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K18909
[Journal Article] Role of microglial activation and neuroinflammation in neurotoxicity of acrylamide in vivo and in vitro2019
- Author(s)
  Zong Cai, Hasegawa Rieka, Urushitani Makoto, Zhang Lingyi, Nagashima Daichi, Sakurai Toshihiro, Ichihara Sahoko, Ohsako Seiichiro, Ichihara Gaku
- Journal Title
  
  Archives of Toxicology
  
  Volume: 印刷中 Issue: 7 Pages: 2007-2019
- DOI
  10.1007/s00204-019-02471-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02965, KAKENHI-PROJECT-17H07105, KAKENHI-PROJECT-19H04279
[Journal Article] Proteomic analysis of hippocampal proteins in acrylamide-exposed Wistar rats2019
- Author(s)
  Daichi Nagashima、Lingyi Zhang、Yuki Kitamura、Sahoko Ichihara、Eri Watanabe、Cai Zong、Yuko Yamano、Toshihiro Sakurai、Shinji Oikawa、Gaku Ichihara
- Journal Title
  
  Archives of Toxicology
  
  Volume: 印刷中
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07105
[Presentation] LPS誘発骨密度減少モデルに対するラロキシフェンの効果とマクロファージの関与2024
- Author(s)
  下里桃子、長嶋大地、鈴木魁、出雲信夫
- Organizer
  第144回日本薬学会年会
- Data Source
  KAKENHI-PROJECT-20K18909
[Presentation] 卵巣摘出高脂肪食マウスの内臓脂肪増加に対する加味逍遙散の効果2024
- Author(s)
  井上真悠子、古川恵、青木亮憲、長嶋大地、出雲信夫
- Organizer
  第144回日本薬学会年会
- Data Source
  KAKENHI-PROJECT-20K18909
[Presentation] PC12細胞に対するラクトフェリンの形態学的評価と薬理学的検討2024
- Author(s)
  小川夏奈、長嶋大地、水上乃愛、大野恵、出雲信夫
- Organizer
  第144回日本薬学会年会
- Data Source
  KAKENHI-PROJECT-23K10859
[Presentation] アクリルアミド誘発神経毒性はノルアドレナリン作動性神経が標的となる2024
- Author(s)
  長嶋大地、市原学、渡邊徹、出雲信夫、山野優子
- Organizer
  第94回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-20K18909
[Presentation] 中枢神経毒性を有する化学物質のヒト曝露事例と動物実験により解明した共通性2024
- Author(s)
  長嶋大地
- Organizer
  第94回日本衛生学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K18909
[Presentation] PC12細胞に対するラクトフェリンの形態学的評価と薬理学的検討2024
- Author(s)
  小川夏奈、長嶋大地、水上乃愛、大野恵、出雲信夫
- Organizer
  第144回日本薬学会年会. 2024年3月
- Data Source
  KAKENHI-PROJECT-20K18909
[Presentation] Aβ注入による記憶障害に対するニコチンアミドモノヌクレオチドの改善効果2024
- Author(s)
  辺もも香、古川恵、石山優奈、青木亮憲、長嶋大地
- Organizer
  第144回日本薬学会年会
- Data Source
  KAKENHI-PROJECT-20K18909
[Presentation] 中枢神経毒性を有する化学物質の共通性に関する洞察2023
- Author(s)
  長嶋大地
- Organizer
  日本衛生学会若手研究者夏の集い2023
- Data Source
  KAKENHI-PROJECT-20K18909
[Presentation] 過酸化水素誘発神経毒性に対するコリアンダーの効果2023
- Author(s)
  小川夏奈、長嶋大地、水上乃愛、飯塚徹、酒井佑宜、出雲信夫、渡邉泰雄
- Organizer
  第24回応用薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-20K18909
[Presentation] 更年期症状に対するはなびらたけの潜在的薬理作用を探る2023
- Author(s)
  長嶋大地、出雲信夫、渡邉泰雄
- Organizer
  第24回応用薬理シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20K18909
[Presentation] ニコチンアミドモノヌクレオチド（NMN）は神経突起を伸長させ記憶力の改善に寄与する2023
- Author(s)
  渡辺もも香、長嶋大地、渡邉泰雄、出雲信夫
- Organizer
  第24回応用薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-20K18909
[Presentation] Acrylamide reduced neurite outgrowth by suppressing p44/42 expression levels in PC12 cells2022
- Author(s)
  Daichi Nagashima, Nobuo Izumo, Takenori Yamauchi, Shigeko Okubo, Yuko Yamano
- Organizer
  33rd International Congress on Occupational Health
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18909
[Presentation] Quantification of bromide ion in biological samples using headspace gas chromatography-mass spectrometer2022
- Author(s)
  Takenori Yamauchi, Daichi Nagashima, Shigeko Okubo, Yuko Yamano
- Organizer
  33rd International Congress on Occupational Health
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K18909
[Presentation] PC12細胞の神経突起伸長に対するラクトフェリンの効果2022
- Author(s)
  水上乃愛、長嶋大地、岩崎莉奈、南條佑磨、古川恵、速水耕介、出雲信夫
- Organizer
  日本薬学会142回年会
- Data Source
  KAKENHI-PROJECT-20K18909
[Presentation] PC12細胞の酸化ストレスに対するコリアンダー効果2022
- Author(s)
  松原智紗、長嶋大地、中川茜、平石直人、渡邉泰雄、出雲信夫
- Organizer
  日本薬学会142回年会
- Data Source
  KAKENHI-PROJECT-20K18909
[Presentation] ニコチンアミドモノヌクレオチドは過酸化水素誘発神経毒性を軽減する2022
- Author(s)
  中川茜、長嶋大地、松原智紗、渡邉泰雄、出雲信夫
- Organizer
  日本薬学会142回年会
- Data Source
  KAKENHI-PROJECT-20K18909
[Presentation] Proteomic Analysis of Liver Proteins of Mice Exposed to 1,2-dichloropropane2019
- Author(s)
  X. Zhang, K. Morikawa, Y. Mori, C. Zong, L. Zhang, E. Garner, C. Huang, W. Wu, J. Chang, D. Nagashima, T. Sakurai, S. Ichihara, S. Oikawa and G. Ichihara
- Organizer
  Society of Toxicology 58th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07105
[Presentation] 1,2-ジクロロプロパン曝露マウスにおける肝臓のプロテオミクス2018
- Author(s)
  森川浩太,　張驍,　森有利絵,　宗才, 張霊逸、エドウィン　ガーナ―、黄晉彦、呉文亭、常杰、長嶋大地、櫻井敏博、市原佐保子、及川伸二、市原学
- Organizer
  第13回ナノ・バイオメディカル学会
- Data Source
  KAKENHI-PROJECT-17H07105
[Presentation] Autophagy in the cerebellar Purkinje cell induced by exposure to acrylamide2017
- Author(s)
  M. Yamamura, K. Morita, T. Matsuzoe, L. Zhang, K. Morita, C. Zhong, D. Nagashima, T. Sakurai, S. Ichihara, G. Ichihara
- Organizer
  10th International Symposium on Biological Monitoring in Occupational and Environmental Health
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07105

1. 出雲信夫 (70368976)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. Yamano Yuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. Ichihara Gaku

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. Ichihara Sahoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. Sakurai Toshihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results

NAGASHIMA Daichi 長嶋 大地

Nagashima Daichi 長嶋 大地

Research Projects

Research Products

Co-Researchers

神経軸索損傷モデルに対するニコチンアミドモノヌクレオチドの新規薬理作用の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

雌性モデルマウスを用いた発達障害様行動に対するラクトフェリンの効果

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

acrylamide誘発神経毒性に対するα-リポ酸の有効性の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of expression mechanism of acrylamide-induce neurotoxicity, and development of therapeutic effects by vitamin B1.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Nicotinamide Mononucleotide (NMN) Enhances Neurite Outgrowth Comparable to Nerve Growth Factor (NGF) in PC12 Cells2022

Author(s)

Journal Title

Data Source

[Journal Article] Effect of Coriander on H2O2-induced Oxidative Stress in PC12 Cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acrylamide reduced neurite outgrowth by suppressing p44/42 expression levels in PC12 cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human Recombinant Lactoferrin Promotes Differentiation and Calcification on MC3T3-E1 Cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Quantification of bromide ion in biological samples using headspace gas chromatography-mass spectrometry2021

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Zinc-containing Mohs’ paste affects blood flow and angiogenesis suppression2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of microglial activation and neuroinflammation in neurotoxicity of acrylamide in vivo and in vitro2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Proteomic analysis of hippocampal proteins in acrylamide-exposed Wistar rats2019

Author(s)

Journal Title

Data Source

[Presentation] LPS誘発骨密度減少モデルに対するラロキシフェンの効果とマクロファージの関与2024

Author(s)

Organizer

Data Source

[Presentation] 卵巣摘出高脂肪食マウスの内臓脂肪増加に対する加味逍遙散の効果2024

Author(s)

Organizer

Data Source

[Presentation] PC12細胞に対するラクトフェリンの形態学的評価と薬理学的検討2024

Author(s)

NAGASHIMA Daichi 長嶋大地

Nagashima Daichi 長嶋大地