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NIIOKA TAKENORI  新岡 丈典

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Niioka Takenori  新岡 丈典

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Researcher Number 20722276
Other IDs
Affiliation (Current) 2025: 弘前大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help 2018 – 2024: 弘前大学, 医学研究科, 教授
2014 – 2017: 秋田大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Basic Section 47060:Clinical pharmacy-related / Medical pharmacy
Except Principal Investigator
Sections That Are Subject to Joint Review: Basic Section02070:Japanese linguistics-related , Basic Section02090:Japanese language education-related / Basic Section 02090:Japanese language education-related / Basic Section 02070:Japanese linguistics-related / Urology
Keywords
Principal Investigator
炎症反応 / TDM / 薬物動態 / 薬物動態関連遺伝子多型 / EGLN1遺伝子多型 / 血中濃度 / 個別化投与設計 / 血中ヘモグロビン値 / 薬物動態関連遺伝子多型解析 / コプロポルフィリン … More / SLCO1B1遺伝子多型 / OATP1B1 / バダデュスタット / 低酸素誘導因子-プロリン水酸化酵素阻害薬 / 遺伝子多型 / 核内レセプター / CRP / C反応性蛋白 / 核内受容体遺伝子多型 / CYP2C19遺伝子多型 / ボリコナゾールN-オキシド体 / ボリコナゾール / 膠原病 / 薬物動態学的相互作用 / イトラコナゾール / エベロリムス / 骨髄移植 / 腎移植 / CYP3A5遺伝子多型 / タクロリムス … More
Except Principal Investigator
津軽弁アーカイブ / 文字音声変換システム / 人工知能 / 津軽弁 / 方言 / 免疫抑制薬 / 腎移植 / 血中濃度 / 腎線維化 / ドナー特異抗体 / CYP3A5 / 繊維増生 / 拒絶反応 / 個別投与量設計 / 画像解析 / 線維増生 / 薬理遺伝学 / 薬物動態 / 遺伝子多型 / タクロリムス Less
  • Research Projects

    (5 results)
  • Research Products

    (32 results)
  • Co-Researchers

    (15 People)
  •  人工知能を活用した津軽弁から共通語への音声・文字情報変換システムの基盤技術開発

    • Principal Investigator
      今井 雅
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 02070:Japanese linguistics-related
      Basic Section 02090:Japanese language education-related
      Sections That Are Subject to Joint Review: Basic Section02070:Japanese linguistics-related , Basic Section02090:Japanese language education-related
    • Research Institution
      Hirosaki University
  •  Individualization of oral hypoxia-inducible factor prolyl hydroxylase inhibitor dosage based on gene polymorphisms related to drug responsivenessPrincipal Investigator

    • Principal Investigator
      新岡 丈典
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Hirosaki University
  •  Effects of C-reactive protein and nuclear receptors on pharmacokinetics of voriconazolePrincipal Investigator

    • Principal Investigator
      Niioka Takenori
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      Hirosaki University
  •  Influence of tacrolimus initial doing strategy based on the CYP3A5 polymorphisms on quantitative interstitial fibrosis, rejection rate, and long-term graft function in kidney transplant recipients.

    • Principal Investigator
      Satoh Shigeru
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Akita University
  •  Do patients taking tacrolimus need to undergo CYP3A5 genotyping along with blood concentration monitoring?Principal Investigator

    • Principal Investigator
      Niioka Takenori
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Akita University

All 2024 2023 2022 2021 2020 2018 2017 2016 2015 Other

All Journal Article Presentation Book

  • [Book] 月刊薬事2017

    • Author(s)
      新岡丈典
    • Total Pages
      5
    • Publisher
      じほう
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Journal Article] Quantification of the plasma concentration of vadadustat by high-performance liquid chromatography with ultraviolet detection and ultra-performance liquid chromatography-tandem mass spectrometry2024

    • Author(s)
      Satoshi Yokoyama, Junichi Nakagawa, Michiko Shimada, Kayo Ueno, Masahiro Ishiyama, Norio Nakamura, Hirofumi Tomita, Takenori Niioka
    • Journal Title

      Ther Drug Monit.

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K06707
  • [Journal Article] Impact of polymorphisms of pharmacokinetics-related genes and the inflammatory response on the metabolism of voriconazole2022

    • Author(s)
      Naoya Aiuchi, Junichi Nakagawa, Hirotake Sakuraba, Takenori Takahata, Kosuke Kamata, Norihiro Saito, Kayo Ueno, Masahiro Ishiyama, Kazufumi Yamagata, Hiroyuki Kayaba, Takenori Niioka
    • Journal Title

      Pharmacology Research & Perspectives

      Volume: 10 (2) Issue: 2

    • DOI

      10.1002/prp2.935

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06778
  • [Journal Article] Prediction of Tacrolimus Exposure by CYP3A5 Genotype and Exposure of Co-Administered Everolimus in Japanese Renal Transplant Recipients.2018

    • Author(s)
      Kagaya H, Niioka T, Saito M, Inoue T, Numakura K, Yamamoto R, Akamine Y, Habuchi T, Satoh S, Miura M.
    • Journal Title

      Int J Mol Sci

      Volume: 19 Issue: 3 Pages: 882-882

    • DOI

      10.3390/ijms19030882

    • NAID

      120007172094

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460189, KAKENHI-PROJECT-18H00362
  • [Journal Article] Prediction of tacrolimus exposure by CYP3A5 genotype and exposure of co-administrated everolimus in Japanes renal transplant recipients.2018

    • Author(s)
      Kagaya H, Niioka T, Saito M, Inoue M, Numakura K, Yamamoto R, Akamine Y, Habuchi T, Satoh S, Miura M.
    • Journal Title

      Int J Mol Sci

      Volume: 19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10636
  • [Journal Article] Influence of CYP3A5 genetic differences in tacrolimus on quantitative interstitianl fibrosis and long-term graft function in kidney transplant recipients.2018

    • Author(s)
      Komine N, Satoh S, Saito M, Numakura K, Inoue T, Tsuruta H, Narita S, Komatsuda A, Nanjo H, Kagaya H, Niioka T, Miura M, Mitobe Y, Habuchi T.
    • Journal Title

      Int Immunopharmacol

      Volume: 58 Pages: 57-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10636
  • [Journal Article] Impact of the CYP3A5 genotype on the distributions of dose-adjusted trough concentrations and incidence of rejection in Japanes renal transplant recipients receiving different tacrolimus formulations.2017

    • Author(s)
      Niioka, T, Kagaya H, Saito S, Inoue T, Numakura K, Yamamoto R, Habuch T, Satoh S, Miura M.
    • Journal Title

      Clin Exp Nephrol

      Volume: 21 Pages: 787-796

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10636
  • [Journal Article] Impact of the CYP3A5 genotype on the distributions of dose-adjusted trough concentrations and incidence of rejection in Japanese renal transplant recipients receiving different tacrolimus formulations.2017

    • Author(s)
      Niioka T, Kagaya H, Satoh S, et al.
    • Journal Title

      Clin Exp Nephrol

      Volume: Mar 7 Pages: 0-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10636
  • [Journal Article] Quantification of intersititial fibrosis in renal allografts and clinical correlates of long-term graft function.2017

    • Author(s)
      Nara M, Komatsuda, Numakura K, Saito M, Inoue T, Niioka T, Miura M, Mitober Y, Okuyama S, Takahashi N, Habuchi T, Satoh S
    • Journal Title

      Am J Nephrol

      Volume: 46 Pages: 187-194

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10636
  • [Journal Article] Impact of the CYP3A5 genotype on the distributions of dose-adjusted trough concentrations and incidence of rejection in Japanese renal transplant recipients receiving different tacrolimus formulations.2017

    • Author(s)
      Niioka T, Kagaya H, Saito M, Inoue T, Numakura K, Yamamoto R, Habuchi T, Satoh.
    • Journal Title

      Clin Exp Nephrol.

      Volume: 印刷中 Issue: 5 Pages: 787-796

    • DOI

      10.1007/s10157-016-1375-4

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Journal Article] Influence of everolimus on the pharmacokinetics of tacrolimus in Japanese renal transplant patients.2016

    • Author(s)
      Niioka T, Kagaya H, Satoh S, et al.
    • Journal Title

      Int J Urol

      Volume: 23 Pages: 484-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10636
  • [Journal Article] Influence of everolimus on the pharmacokinetics of tacrolimus in Japanese renal transplant patients.2016

    • Author(s)
      Niioka T, Kagaya H, Saito M, Inoue T, Numakura K, Yamamoto R, Akamine Y, Habuchi T, Satoh S, Miura M.
    • Journal Title

      Int J Urol.

      Volume: in press Issue: 6 Pages: 484-490

    • DOI

      10.1111/iju.13081

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Journal Article] Effect of CYP3A5 and ABCB1 polymorphisms on the interaction between tacrolimus and itraconazole in patients with connective tissue disease.2015

    • Author(s)
      Togashi M, Niioka T, Komatsuda A, Nara M, Okuyama S, Omokawa A, Abumiya M, Wakui H, Takahashi N, Miura M.
    • Journal Title

      Eur J Clin Pharmacol.

      Volume: 71 Issue: 9 Pages: 1091-7

    • DOI

      10.1007/s00228-015-1901-4

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Journal Article] Effects of CYP3A5 polymorphism and the tacrolimus 12?h concentration on tacrolimus-induced acute renal dysfunction in patients with lupus nephritis.2015

    • Author(s)
      Niioka T, Komatsuda A, Kato S, Togashi M, Okuyama S, Omokawa A, Nara M, Wakui H, Takahashi N, Miura M.
    • Journal Title

      Xenobiotica.

      Volume: 45 Pages: 1147-53

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Journal Article] Capability of utilizing CYP3A5 polymorphisms to predict therapeutic dosage of tacrolimus at early stage post-renal transplantation.2015

    • Author(s)
      Niioka T, Kagaya H, Saito M, Inoue T, Numakura K, Habuchi T, Satoh S, Miura M.
    • Journal Title

      Int J Mol Sci.

      Volume: 16 Issue: 1 Pages: 1840-1854

    • DOI

      10.3390/ijms16011840

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Journal Article] Capability of utilizing CYP3A5 polymorphisms to predict therapeutic dosage of tacrolimus at early stage post-renal transplantation2015

    • Author(s)
      Niioka T, Kagaya H, Saito M, Inoue T, Numakura K, Habuchi T, Satoh S, Miura M.
    • Journal Title

      Int J Mol Sci

      Volume: 16 Pages: 1840-1854

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10636
  • [Presentation] HPLC-UV法を用いたバダデュスタットの血漿中濃度測定系の確立2023

    • Author(s)
      横山 智士、中川 潤一、島田 美智子、上野 桂代、石山 雅大、中村 典雄、富田 泰史、新岡 丈典
    • Organizer
      第33回日本医療薬学会年会
    • Data Source
      KAKENHI-PROJECT-21K06707
  • [Presentation] ボリコナゾールの薬物動態に及ぼすCYP2C19、CYP3A5、FMO3、NR1I2、NR1I3、POR遺伝子多型及び炎症反応の影響2022

    • Author(s)
      相内 尚也、中川 潤一、櫻庭 裕丈、髙畑 武功、鎌田 耕輔、齋藤 紀先、上野 桂代、石山 雅大、山形 和史、萱場 広之、新岡 丈典
    • Organizer
      第38回日本TDM学会・学術大会
    • Data Source
      KAKENHI-PROJECT-18K06778
  • [Presentation] 薬物血中濃度モニタリングに薬物動態関連遺伝子多型情報を如何に活用すべきか2021

    • Author(s)
      新岡 丈典
    • Organizer
      第42回日本臨床薬理学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K06778
  • [Presentation] ボリコナゾールの体内動態に及ぼすCYP2C19遺伝子多型およびC反応性蛋白の影響2020

    • Author(s)
      相内 尚也、中川 潤一、上野 桂代、木村 正彦、萱場 広之、新岡 丈典
    • Organizer
      日本薬学会第140年会
    • Data Source
      KAKENHI-PROJECT-18K06778
  • [Presentation] ボリコナゾール投与患者における炎症反応がCYP2C19活性に及ぼす影響2020

    • Author(s)
      相内尚也、中川潤一、上野桂代、木村正彦、萱場広之、新岡丈典
    • Organizer
      第30回医療薬学会年会
    • Data Source
      KAKENHI-PROJECT-18K06778
  • [Presentation] 腎移植患者におけるタクロリムス体内曝露量の個体間変動に及ぼすCYP3A5遺伝子多型およびエベロリムスの影響2017

    • Author(s)
      加賀谷 英彰、新岡 丈典、齋藤 満、井上 高光、沼倉 一幸、羽渕 友則、佐藤 滋、三浦 昌朋
    • Organizer
      医療薬学会
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Presentation] 遺伝子多型に基づく免疫抑制薬投与計画の個別化へのアプローチ2016

    • Author(s)
      新岡丈典
    • Organizer
      第52回日本移植学会総会
    • Place of Presentation
      東京
    • Year and Date
      2016-09-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Presentation] 遺伝子多型情報を用いた抗がん剤と免疫抑制剤の個別化投与設計2016

    • Author(s)
      新岡丈典,三浦昌朋
    • Organizer
      日本薬物動態学会第31回年会
    • Place of Presentation
      松本
    • Year and Date
      2016-10-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Presentation] タクロリムス個別化投与設計においてCYP3A5遺伝子多型情報を有効利用するために2016

    • Author(s)
      新岡丈典
    • Organizer
      日本病院薬剤師会東北ブロック第6回学術大会
    • Place of Presentation
      郡山
    • Year and Date
      2016-05-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Presentation] 血液がん領域におけるTDMの実践と個別化療法への応用2016

    • Author(s)
      新岡丈典
    • Organizer
      日本TDM学会第49回セミナー
    • Place of Presentation
      仙台
    • Year and Date
      2016-09-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Presentation] タクロリムスTDMにおけるCYP3A5遺伝子多型解析の有用性と経済的効果2015

    • Author(s)
      新岡 丈典
    • Organizer
      第32回日本TDM学会・学術大会
    • Place of Presentation
      松本
    • Year and Date
      2015-05-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Presentation] ループス腎炎患者の急性腎障害発症に及ぼすタクロリムスの血中濃度とCYP3A5遺伝子多型の影響2015

    • Author(s)
      富樫賢, 新岡丈典, 奈良瑞穂, 面川歩, 奥山慎, 加藤正太郎, 涌井秀樹, 三浦昌朋, 小松田敦
    • Organizer
      第58回日本腎臓学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Presentation] 臨床濃度範囲でエベロリムスはタクロリムス体内動態に影響しない2015

    • Author(s)
      新岡丈典, 加賀谷英彰, 齋藤満, 井上高光, 沼倉一幸, 羽渕友則, 佐藤滋, 三浦昌朋
    • Organizer
      第51回日本移植学会総会
    • Place of Presentation
      熊本
    • Year and Date
      2015-10-01
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Presentation] 膠原病患者におけるタクロリムスとイトラコナゾールとの薬物相互作用に及ぼすCYP3A5およびABCB1遺伝子多型の影響2015

    • Author(s)
      新岡丈典, 富樫賢, 小松田敦, 奈良瑞穂, 奥山慎, 面川歩, 鐙屋舞子, 涌井秀樹, 高橋直人, 三浦昌朋
    • Organizer
      日本医療薬学会第25回年会
    • Place of Presentation
      横浜
    • Year and Date
      2015-11-21
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Presentation] Influence of CYP3A5 gene polymorphisms on pharmacokinetics of tacrolimus modified-release once-daily after hematopoietic stem cell transplantation.2015

    • Author(s)
      Takaya Yamashita, Naohito Fujishima, Masatomo Miura, Takenori Niioka, Maiko Abumiya, Kazuaki Teshima, Kumi Ubukawa, Miho Nara, Masumi Fujishima, Yoshihiro Kameoka, Makoto Hirokawa, Naoto Takahashi
    • Organizer
      20th Congress of European Hematology Association
    • Place of Presentation
      Vienna
    • Year and Date
      2015-06-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460189
  • [Presentation] タクロリムス至適投与量に対する決定要因の経時的検討

    • Author(s)
      新岡丈典、加賀谷英彰、齋藤満、井上高光、沼倉一幸、羽渕友則、佐藤滋、三浦昌朋
    • Organizer
      第50回日本移植学会総会
    • Place of Presentation
      京王プラザホテル(東京)
    • Year and Date
      2014-09-10 – 2014-09-12
    • Data Source
      KAKENHI-PROJECT-26460189
  • 1.  MIURA Masatomo (30265194)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 17 results
  • 2.  SATOH Shigeru (80187195)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 14 results
  • 3.  TAKAHASHI Naoto (80344753)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 4.  SAITO MITSURU (80400505)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 5.  KOMATSUDA ATSUSHI (70272044)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  OKUYAMA SHIN (40543286)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  FUJIYAMA NOBUHIRO (90603275)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  今井 雅 (70323665)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  柏倉 幾郎 (00177370)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  井瀧 千恵子 (00285008)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  松崎 正敏 (10355688)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  辻口 貴清 (90737454)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  杉山 祐子 (30196779)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  吉仲 怜 (70548487)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KAGAYA Hideaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results

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