NIIOKA TAKENORI 新岡丈典

… Alternative Names

Researcher Number	20722276
Affiliation (Current)	2022: 弘前大学, 医学研究科, 教授
Affiliation (based on the past Project Information) *help	2018 – 2021: 弘前大学, 医学研究科, 教授 2014 – 2017: 秋田大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Medical pharmacy Except Principal Investigator Urology
Keywords	Principal Investigator TDM / タクロリムス / CYP3A5遺伝子多型 / 薬物動態 / 腎移植 / 骨髄移植 / エベロリムス / イトラコナゾール / 薬物動態学的相互作用 / 膠原病 … More Except Principal Investigator タクロリムス / 遺伝子多型 / 薬物動態 / 薬理遺伝学 / 線維増生 / 画像解析 / 個別投与量設計 / 拒絶反応 / 繊維増生 / CYP3A5 / ドナー特異抗体 / 腎線維化 / 血中濃度 / 腎移植 / 免疫抑制薬 Less

Individualization of oral hypoxia-inducible factor prolyl hydroxylase inhibitor dosage based on gene polymorphisms related to drug responsivenessPrincipal Investigator
- Principal Investigator
  
  新岡丈典
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Hirosaki University
Effects of C-reactive protein and nuclear receptors on pharmacokinetics of voriconazolePrincipal Investigator
- Principal Investigator
  
  新岡丈典
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Hirosaki University
Influence of tacrolimus initial doing strategy based on the CYP3A5 polymorphisms on quantitative interstitial fibrosis, rejection rate, and long-term graft function in kidney transplant recipients.
- Principal Investigator
  
  Satoh Shigeru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Akita University
Do patients taking tacrolimus need to undergo CYP3A5 genotyping along with blood concentration monitoring?Principal Investigator
- Principal Investigator
  
  Niioka Takenori
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Akita University

All 2020 2018 2017 2016 2015 Other

All Journal Article Presentation Book

[Book] 月刊薬事2017
- Author(s)
  新岡丈典
- Total Pages
  5
- Publisher
  じほう
- Data Source
  KAKENHI-PROJECT-26460189
[Journal Article] Prediction of Tacrolimus Exposure by CYP3A5 Genotype and Exposure of Co-Administered Everolimus in Japanese Renal Transplant Recipients.2018
- Author(s)
  Kagaya H
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Pages: 882-882
- DOI
  10.3390/ijms19030882
- NAID
  120007172094
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460189, KAKENHI-PROJECT-18H00362
[Journal Article] Prediction of tacrolimus exposure by CYP3A5 genotype and exposure of co-administrated everolimus in Japanes renal transplant recipients.2018
- Author(s)
  Kagaya H, Niioka T, Saito M, Inoue M, Numakura K, Yamamoto R, Akamine Y, Habuchi T, Satoh S, Miura M.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10636
[Journal Article] Influence of CYP3A5 genetic differences in tacrolimus on quantitative interstitianl fibrosis and long-term graft function in kidney transplant recipients.2018
- Author(s)
  Komine N, Satoh S, Saito M, Numakura K, Inoue T, Tsuruta H, Narita S, Komatsuda A, Nanjo H, Kagaya H, Niioka T, Miura M, Mitobe Y, Habuchi T.
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 58 Pages: 57-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10636
[Journal Article] Impact of the CYP3A5 genotype on the distributions of dose-adjusted trough concentrations and incidence of rejection in Japanes renal transplant recipients receiving different tacrolimus formulations.2017
- Author(s)
  Niioka, T, Kagaya H, Saito S, Inoue T, Numakura K, Yamamoto R, Habuch T, Satoh S, Miura M.
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 21 Pages: 787-796
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10636
[Journal Article] Impact of the CYP3A5 genotype on the distributions of dose-adjusted trough concentrations and incidence of rejection in Japanese renal transplant recipients receiving different tacrolimus formulations.2017
- Author(s)
  Niioka T, Kagaya H, Satoh S, et al.
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: Mar 7 Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10636
[Journal Article] Quantification of intersititial fibrosis in renal allografts and clinical correlates of long-term graft function.2017
- Author(s)
  Nara M, Komatsuda, Numakura K, Saito M, Inoue T, Niioka T, Miura M, Mitober Y, Okuyama S, Takahashi N, Habuchi T, Satoh S
- Journal Title
  
  Am J Nephrol
  
  Volume: 46 Pages: 187-194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10636
[Journal Article] Impact of the CYP3A5 genotype on the distributions of dose-adjusted trough concentrations and incidence of rejection in Japanese renal transplant recipients receiving different tacrolimus formulations.2017
- Author(s)
  Niioka T, Kagaya H, Saito M, Inoue T, Numakura K, Yamamoto R, Habuchi T, Satoh.
- Journal Title
  
  Clin Exp Nephrol.
  
  Volume: 印刷中
- DOI
  10.1007/s10157-016-1375-4
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460189
[Journal Article] Influence of everolimus on the pharmacokinetics of tacrolimus in Japanese renal transplant patients.2016
- Author(s)
  Niioka T, Kagaya H, Satoh S, et al.
- Journal Title
  
  Int J Urol
  
  Volume: 23 Pages: 484-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10636
[Journal Article] Influence of everolimus on the pharmacokinetics of tacrolimus in Japanese renal transplant patients.2016
- Author(s)
  Niioka T, Kagaya H, Saito M, Inoue T, Numakura K, Yamamoto R, Akamine Y, Habuchi T, Satoh S, Miura M.
- Journal Title
  
  Int J Urol.
  
  Volume: in press
- DOI
  10.1111/iju.13081
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460189
[Journal Article] Effect of CYP3A5 and ABCB1 polymorphisms on the interaction between tacrolimus and itraconazole in patients with connective tissue disease.2015
- Author(s)
  Togashi M, Niioka T, Komatsuda A, Nara M, Okuyama S, Omokawa A, Abumiya M, Wakui H, Takahashi N, Miura M.
- Journal Title
  
  Eur J Clin Pharmacol.
  
  Volume: 71 Pages: 1091-7
- DOI
  10.1007/s00228-015-1901-4
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460189
[Journal Article] Effects of CYP3A5 polymorphism and the tacrolimus 12?h concentration on tacrolimus-induced acute renal dysfunction in patients with lupus nephritis.2015
- Author(s)
  Niioka T, Komatsuda A, Kato S, Togashi M, Okuyama S, Omokawa A, Nara M, Wakui H, Takahashi N, Miura M.
- Journal Title
  
  Xenobiotica.
  
  Volume: 45 Pages: 1147-53
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460189
[Journal Article] Capability of utilizing CYP3A5 polymorphisms to predict therapeutic dosage of tacrolimus at early stage post-renal transplantation.2015
- Author(s)
  Niioka T, Kagaya H, Saito M, Inoue T, Numakura K, Habuchi T, Satoh S, Miura M.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 16 Pages: 1840-1854
- DOI
  10.3390/ijms16011840
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460189
[Journal Article] Capability of utilizing CYP3A5 polymorphisms to predict therapeutic dosage of tacrolimus at early stage post-renal transplantation2015
- Author(s)
  Niioka T, Kagaya H, Saito M, Inoue T, Numakura K, Habuchi T, Satoh S, Miura M.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 16 Pages: 1840-1854
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10636
[Presentation] ボリコナゾールの体内動態に及ぼすCYP2C19遺伝子多型およびC反応性蛋白の影響2020
- Author(s)
  相内尚也、中川潤一、上野桂代、木村正彦、萱場広之、新岡丈典
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K06778
[Presentation] ボリコナゾール投与患者における炎症反応がCYP2C19活性に及ぼす影響2020
- Author(s)
  相内尚也、中川潤一、上野桂代、木村正彦、萱場広之、新岡丈典
- Organizer
  第30回医療薬学会年会
- Data Source
  KAKENHI-PROJECT-18K06778
[Presentation] 腎移植患者におけるタクロリムス体内曝露量の個体間変動に及ぼすCYP3A5遺伝子多型およびエベロリムスの影響2017
- Author(s)
  加賀谷　英彰、新岡　丈典、齋藤　満、井上　高光、沼倉　一幸、羽渕　友則、佐藤　滋、三浦　昌朋
- Organizer
  医療薬学会
- Data Source
  KAKENHI-PROJECT-26460189
[Presentation] 遺伝子多型に基づく免疫抑制薬投与計画の個別化へのアプローチ2016
- Author(s)
  新岡丈典
- Organizer
  第52回日本移植学会総会
- Place of Presentation
  東京
- Year and Date
  2016-09-29
- Invited
- Data Source
  KAKENHI-PROJECT-26460189
[Presentation] 遺伝子多型情報を用いた抗がん剤と免疫抑制剤の個別化投与設計2016
- Author(s)
  新岡丈典，三浦昌朋
- Organizer
  日本薬物動態学会第31回年会
- Place of Presentation
  松本
- Year and Date
  2016-10-13
- Invited
- Data Source
  KAKENHI-PROJECT-26460189
[Presentation] タクロリムス個別化投与設計においてCYP3A5遺伝子多型情報を有効利用するために2016
- Author(s)
  新岡丈典
- Organizer
  日本病院薬剤師会東北ブロック第6回学術大会
- Place of Presentation
  郡山
- Year and Date
  2016-05-21
- Invited
- Data Source
  KAKENHI-PROJECT-26460189
[Presentation] 血液がん領域におけるTDMの実践と個別化療法への応用2016
- Author(s)
  新岡丈典
- Organizer
  日本TDM学会第49回セミナー
- Place of Presentation
  仙台
- Year and Date
  2016-09-03
- Invited
- Data Source
  KAKENHI-PROJECT-26460189
[Presentation] タクロリムスTDMにおけるCYP3A5遺伝子多型解析の有用性と経済的効果2015
- Author(s)
  新岡丈典
- Organizer
  第32回日本TDM学会・学術大会
- Place of Presentation
  松本
- Year and Date
  2015-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-26460189
[Presentation] ループス腎炎患者の急性腎障害発症に及ぼすタクロリムスの血中濃度とCYP3A5遺伝子多型の影響2015
- Author(s)
  富樫賢, 新岡丈典, 奈良瑞穂, 面川歩, 奥山慎, 加藤正太郎, 涌井秀樹, 三浦昌朋, 小松田敦
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-26460189
[Presentation] 臨床濃度範囲でエベロリムスはタクロリムス体内動態に影響しない2015
- Author(s)
  新岡丈典, 加賀谷英彰, 齋藤満, 井上高光, 沼倉一幸, 羽渕友則, 佐藤滋, 三浦昌朋
- Organizer
  第51回日本移植学会総会
- Place of Presentation
  熊本
- Year and Date
  2015-10-01
- Data Source
  KAKENHI-PROJECT-26460189
[Presentation] 膠原病患者におけるタクロリムスとイトラコナゾールとの薬物相互作用に及ぼすCYP3A5およびABCB1遺伝子多型の影響2015
- Author(s)
  新岡丈典, 富樫賢, 小松田敦, 奈良瑞穂, 奥山慎, 面川歩, 鐙屋舞子, 涌井秀樹, 高橋直人, 三浦昌朋
- Organizer
  日本医療薬学会第25回年会
- Place of Presentation
  横浜
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-26460189
[Presentation] Influence of CYP3A5 gene polymorphisms on pharmacokinetics of tacrolimus modified-release once-daily after hematopoietic stem cell transplantation.2015
- Author(s)
  Takaya Yamashita, Naohito Fujishima, Masatomo Miura, Takenori Niioka, Maiko Abumiya, Kazuaki Teshima, Kumi Ubukawa, Miho Nara, Masumi Fujishima, Yoshihiro Kameoka, Makoto Hirokawa, Naoto Takahashi
- Organizer
  20th Congress of European Hematology Association
- Place of Presentation
  Vienna
- Year and Date
  2015-06-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460189
[Presentation] タクロリムス至適投与量に対する決定要因の経時的検討
- Author(s)
  新岡丈典、加賀谷英彰、齋藤満、井上高光、沼倉一幸、羽渕友則、佐藤滋、三浦昌朋
- Organizer
  第50回日本移植学会総会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2014-09-10 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-26460189

1. MIURA Masatomo (30265194)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
2. SATOH Shigeru (80187195)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
3. TAKAHASHI Naoto (80344753)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. SAITO MITSURU (80400505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. KOMATSUDA ATSUSHI (70272044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. OKUYAMA SHIN (40543286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. FUJIYAMA NOBUHIRO (90603275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KAGAYA Hideaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results

NIIOKA TAKENORI 新岡 丈典

Niioka Takenori 新岡 丈典

Research Projects

Research Products

Co-Researchers

Individualization of oral hypoxia-inducible factor prolyl hydroxylase inhibitor dosage based on gene polymorphisms related to drug responsivenessPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of C-reactive protein and nuclear receptors on pharmacokinetics of voriconazolePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Influence of tacrolimus initial doing strategy based on the CYP3A5 polymorphisms on quantitative interstitial fibrosis, rejection rate, and long-term graft function in kidney transplant recipients.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Do patients taking tacrolimus need to undergo CYP3A5 genotyping along with blood concentration monitoring?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 月刊薬事2017

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Prediction of Tacrolimus Exposure by CYP3A5 Genotype and Exposure of Co-Administered Everolimus in Japanese Renal Transplant Recipients.2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Prediction of tacrolimus exposure by CYP3A5 genotype and exposure of co-administrated everolimus in Japanes renal transplant recipients.2018

Author(s)

Journal Title

Data Source

[Journal Article] Influence of CYP3A5 genetic differences in tacrolimus on quantitative interstitianl fibrosis and long-term graft function in kidney transplant recipients.2018

Author(s)

Journal Title

Data Source

[Journal Article] Impact of the CYP3A5 genotype on the distributions of dose-adjusted trough concentrations and incidence of rejection in Japanes renal transplant recipients receiving different tacrolimus formulations.2017

Author(s)

Journal Title

Data Source

[Journal Article] Impact of the CYP3A5 genotype on the distributions of dose-adjusted trough concentrations and incidence of rejection in Japanese renal transplant recipients receiving different tacrolimus formulations.2017

Author(s)

Journal Title

Data Source

[Journal Article] Quantification of intersititial fibrosis in renal allografts and clinical correlates of long-term graft function.2017

Author(s)

Journal Title

Data Source

[Journal Article] Impact of the CYP3A5 genotype on the distributions of dose-adjusted trough concentrations and incidence of rejection in Japanese renal transplant recipients receiving different tacrolimus formulations.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Influence of everolimus on the pharmacokinetics of tacrolimus in Japanese renal transplant patients.2016

Author(s)

Journal Title

Data Source

[Journal Article] Influence of everolimus on the pharmacokinetics of tacrolimus in Japanese renal transplant patients.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of CYP3A5 and ABCB1 polymorphisms on the interaction between tacrolimus and itraconazole in patients with connective tissue disease.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of CYP3A5 polymorphism and the tacrolimus 12?h concentration on tacrolimus-induced acute renal dysfunction in patients with lupus nephritis.2015

NIIOKA TAKENORI 新岡丈典

Niioka Takenori 新岡丈典