Tanaka Hiroki 田中宏樹

… Alternative Names

田中宏樹タナカヒロキ

TANAKA HIROKI 田中宏樹

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Researcher Number	20725452
Other IDs	https://orcid.org/0000-0003-3469-6555
Affiliation (Current)	2025: 京都大学, 医学研究科, 特定助教
Affiliation (based on the past Project Information) *help	2021: 京都大学, 医学研究科, 特定助教 2018 – 2019: 京都大学, 医学研究科, 特定助教 2018: 愛知県がんセンター(研究所), 腫瘍医化学部, リサーチレジデント 2014 – 2015: 愛知県がんセンター(研究所), 腫瘍医化学部, リサーチレジデント
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Pathobiological dentistry/Dental radiology Except Principal Investigator Cell biology
Keywords	Principal Investigator がん微小環境 / ケモタキシス / Sipa1 / Rap1 / CML(幹)細胞 / T細胞 / 間葉系幹細胞 / 染色体異数性 Except Principal Investigator 中間系フィラメント / 染色体 … More / 中心体 / 分化 / aneuploidy / 染色体不安定性 / がん化 / 老化 / 細胞質分裂 / 中間径フィラメント / 染色体異数性 Less

免疫系とストローマ細胞による癌制御の分子基盤の解明Principal Investigator
- Principal Investigator
  
  田中宏樹
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kyoto University
Uncover molecular basis on cancer microenvironment regulating leukemia stem cellsPrincipal Investigator
- Principal Investigator
  
  TANAKA HIROKI
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kyoto University
The fate of aneuploid cells
- Principal Investigator
  
  Inagaki Masaki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cell biology
- Research Institution
  Mie University
Development of a new mouse model caused aneuploidyPrincipal Investigator
- Principal Investigator
  
  Tanaka Hiroki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Aichi Cancer Center Research Institute

All 2019 2018 2016 2015 Other

All Journal Article Presentation Book

[Book] 月刊細胞2015
- Author(s)
  後藤英仁、田中宏樹、稲垣昌樹
- Total Pages
  4
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-26861585
[Journal Article] Rap1 signal modulators control the maintenance of hematopoietic progenitors in bone marrow and adult long-term hematopoiesis2019
- Author(s)
  Imai T, Tanaka H, Hamazaki Y, Minato N
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 4 Pages: 1317-1330
- DOI
  10.1111/cas.13974
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15209, KAKENHI-PROJECT-18K19442, KAKENHI-PUBLICLY-17H05641, KAKENHI-PROJECT-18H02640
[Journal Article] Thymic Development of a Unique Bone Marrow-Resident Innate-like T Cell Subset with a Potent Innate Immune Function2019
- Author(s)
  Ryusuke Yamamoto, Yan Xu, Satoshi Ikeda, Kentaro Sumida, Hiroki Tanaka, Katsuto Hozumi, Akifumi Takaori-Kondo and Nagahiro Minato
- Journal Title
  
  The Journal of Immunology
  
  Volume: 203 Issue: 1 Pages: 167-177
- DOI
  10.4049/jimmunol.1900111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15209
[Journal Article] Tetraploidy in cancer and its possible link to aging.2018
- Author(s)
  Tanaka K, Goto H, Nishimura Y, Kasahara K, Mizoguchi A, Inagaki M.
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 9 Pages: 2632-2640
- DOI
  10.1111/cas.13717
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08269, KAKENHI-PROJECT-15H02398, KAKENHI-PROJECT-18H02434, KAKENHI-PROJECT-16K08547, KAKENHI-PUBLICLY-18H04896
[Journal Article] Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells2018
- Author(s)
  Xu Yan、Ikeda Satoshi、Sumida Kentaro、Yamamoto Ryusuke、Tanaka Hiroki、Minato Nagahiro
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 914-914
- DOI
  10.1038/s41467-018-03307-8
- NAID
  120006406847
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24111008, KAKENHI-PROJECT-18K15209
[Journal Article] EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase2018
- Author(s)
  Kasahara K, Aoki H, Kiyono T, Wang S, Kagiwada H, Yuge M, Tanaka T, Nishimura Y, Mizoguchi A, Goshima N, Inagaki M
- Journal Title
  
  Nat Commun
  
  Volume: 9 Issue: 1 Pages: 758-758
- DOI
  10.1038/s41467-018-03117-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08269, KAKENHI-PLANNED-24113005, KAKENHI-PROJECT-15H02398, KAKENHI-PROJECT-16K08547
[Journal Article] Desmin phosphorylation by Cdk1 is required for efficient separation of desmin intermediate filaments in mitosis and detected in murine embryonic/newborn muscle and human rhabdomyosarcoma tissues.2016
- Author(s)
  Makihara H., Inaba H., Enomoto A., Tanaka H., Tomono Y., Ushida K., Goto M., Kurita K., Nishida Y., Kasahara K., Goto H., and Inagaki M.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 478 Issue: 3 Pages: 1323-1329
- DOI
  10.1016/j.bbrc.2016.08.122
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08324, KAKENHI-PROJECT-15H02398
[Journal Article] Phospho-Specific Antibody Probes of Intermediate Filament Proteins2016
- Author(s)
  Goto H, Tanaka H, Kasahara K, Inagaki M.
- Journal Title
  
  Methods in Enzymology
  
  Volume: 568 Pages: 85-111
- DOI
  10.1016/bs.mie.2015.07.010
- ISBN
  9780128034705
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24113005, KAKENHI-PROJECT-25460089, KAKENHI-PROJECT-26861585, KAKENHI-PROJECT-15H02398
[Journal Article] Cytokinetic failure-induced tetraploidy develops into aneuploidy, triggering skin aging in phospho-vimentin deficient mice.2015
- Author(s)
  Tanaka, H., Goto, H., Inoko, A., Makihara, H., Enomoto, A., Horimoto, K., Matsuyama, M., Kurita, K., Izawa, I., and Inagaki, M.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Issue: 21 Pages: 12984-12998
- DOI
  10.1074/jbc.m114.633891
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-24113005, KAKENHI-PROJECT-26440111, KAKENHI-PROJECT-26670650, KAKENHI-PROJECT-26861585, KAKENHI-PROJECT-15K08324
[Presentation] Sipa1 deficiency unleashes a potent host anti-cancer immune mechanism2019
- Author(s)
  Yan Xu, Satoshi Ikeda, Kentaro Sumida, Ryusuke Yamamoto, Hiroki Tanaka, Nagahiro Minato
- Organizer
  Keystone Symposia Cancer Metastasis: The Role of Metabolism, Immunity and the Microenvironment
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15209
[Presentation] Sipa1 deficient mouse rejects cancer cell through immune cell migration into the tumor tissue2019
- Author(s)
  Ikeda Satoshi, Yan Xu, Kentaro Sumida, Ryusuke Yamamoto, Hiroki Tanaka, Nagahiro Minato
- Organizer
  CSHL Meeting on Biology of Cancer; Microenvironment & Metastasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15209
[Presentation] Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells2018
- Author(s)
  Yan Xu, Satoshi Ikeda, Kentaro Sumida, Ryusuke Yamamoto, Hiroki Tanaka, Nagahiro Minato
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15209
[Presentation] Sipa1 deficiency uncovers a host-immune mechanism eradicating CML-initiating cells2018
- Author(s)
  Hiroki Tanaka, Yan Xu, Satoshi Ikeda, Kentaro Sumida, Ryusuke Yamamoto, Nagahiro Minato
- Organizer
  CSHL Meeting on Mechanisms & Models of Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15209
[Presentation] Vimenti phospho-deficient mice display aneuploidy and skin premature aging2015
- Author(s)
  田中宏樹、後藤英仁、猪子誠人、牧原博幸、榎本篤、井澤一郎、稲垣昌樹
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26861585
[Presentation] 分裂期ビメンチンリン酸化不全マウスは染色体異数性と老化を引き起こす
- Author(s)
  田中宏樹、後藤英仁、猪子誠人、井澤一郎、稲垣昌樹
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26861585
[Presentation] Phosphorylation-deficient vimentin mutant mice develop premature aging via aneuploidy and cellular senescence
- Author(s)
  Tanaka H., Goto H., Inoko A., Makihara H., Izawa I., and Inagaki M.
- Organizer
  Gordon Research Conference - Intermediate Filaments
- Place of Presentation
  West Dover, USA
- Year and Date
  2014-06-15 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-26861585

1. Inagaki Masaki (30183007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 後藤英仁 (20393126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 笠原広介 (90455535)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 猪子誠人 (30393127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 井澤一郎 (20311441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 湊長博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanaka Hiroki 田中 宏樹

田中 宏樹 タナカ ヒロキ

TANAKA HIROKI 田中 宏樹

Research Projects

Research Products

Co-Researchers

免疫系とストローマ細胞による癌制御の分子基盤の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Uncover molecular basis on cancer microenvironment regulating leukemia stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The fate of aneuploid cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a new mouse model caused aneuploidyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 月刊 細胞2015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Rap1 signal modulators control the maintenance of hematopoietic progenitors in bone marrow and adult long-term hematopoiesis2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Thymic Development of a Unique Bone Marrow-Resident Innate-like T Cell Subset with a Potent Innate Immune Function2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tetraploidy in cancer and its possible link to aging.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Desmin phosphorylation by Cdk1 is required for efficient separation of desmin intermediate filaments in mitosis and detected in murine embryonic/newborn muscle and human rhabdomyosarcoma tissues.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phospho-Specific Antibody Probes of Intermediate Filament Proteins2016

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Cytokinetic failure-induced tetraploidy develops into aneuploidy, triggering skin aging in phospho-vimentin deficient mice.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] Sipa1 deficiency unleashes a potent host anti-cancer immune mechanism2019

Author(s)

Organizer

Tanaka Hiroki 田中宏樹

田中宏樹タナカヒロキ

TANAKA HIROKI 田中宏樹

[Book] 月刊細胞2015