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Kyogoku Hirohisa  京極 博久

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Hirohisa Kyogoku  京極 博久

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Researcher Number 20726038
Other IDs
Affiliation (Current) 2025: 神戸大学, 農学研究科, 准教授
Affiliation (based on the past Project Information) *help 2025: 神戸大学, 農学研究科, 助教
2020 – 2023: 神戸大学, 農学研究科, 助教
2019: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 研究員
2015 – 2016: 国立研究開発法人理化学研究所, 多細胞システム形成研究センター, 訪問研究員
Review Section/Research Field
Principal Investigator
Transformative Research Areas, Section (III) / Biological Sciences / Basic Section 38060:Applied molecular and cellular biology-related / Applied molecular and cellular biology
Except Principal Investigator
Cell biology
Keywords
Principal Investigator
初期胚 / 全能性 / 受精卵 / マウス / ライブイメージング / 卵母細胞 / 片親性ダイソミー / 染色体分配異常 / ヒストンメチル化 / ヒストン … More / サイズ / 前核 / スケーリング / メチル化 / 核サイズ / 染色体分配 / 細胞サイズ / 紡錘体 / 微小管 / ライブセルイメージング / SAC / 顕微操作 / 減数分裂 / 紡錘体形成チェックポイント … More
Except Principal Investigator
減数分裂 / 染色体分配 / 紡錘体 / 卵母細胞 Less
  • Research Projects

    (8 results)
  • Research Products

    (21 results)
  • Co-Researchers

    (2 People)
  •  Understanding Early Embryonic Developmental Strategies: Risk management in early embryonic developmentArea Organizer

    • Area Organizer
      京極 博久
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
  •  初期胚の発生戦略の理解:発生におけるリスクマネジメントPrincipal Investigator

    • Principal Investigator
      京極 博久
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Kobe University
  •  初期胚が持つ染色体分配異常へのリスクマネジメントPrincipal Investigator

    • Principal Investigator
      京極 博久
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Kobe University
  •  Elucidation of the mechanism by which zygotes recovers from abnormal chromosome segregation to maintain totipotencyPrincipal Investigator

    • Principal Investigator
      京極 博久
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  Elucidation of totipotency acquisition mechanism controlled by nuclear sizePrincipal Investigator

    • Principal Investigator
      京極 博久
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
  •  Elucidation of the cause of changes in the frequency of chromosome segregation error during early embryonic developmentPrincipal Investigator

    • Principal Investigator
      Kyogoku Hirohisa
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 38060:Applied molecular and cellular biology-related
    • Research Institution
      Kobe University
      Institute of Physical and Chemical Research
  •  Why is the spindle assembly checkpoint weak in oocytes?Principal Investigator

    • Principal Investigator
      Hirohisa Kyogoku
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Applied molecular and cellular biology
    • Research Institution
      Institute of Physical and Chemical Research
  •  Oocyte-specific spindle scaling

    • Principal Investigator
      Kitajima Tomoya
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Cell biology
    • Research Institution
      Institute of Physical and Chemical Research

All 2024 2023 2021 2020 2019 2017 2016 2015 2014

All Journal Article Presentation

  • [Journal Article] Large Cytoplasm Is Linked to the Error-Prone Nature of Oocytes2017

    • Author(s)
      Hirohisa Kyogoku, Tomoya S. Kitajima
    • Journal Title

      Developmental cell

      Volume: 41 Issue: 3 Pages: 287-298

    • DOI

      10.1016/j.devcel.2017.04.009

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-14J02961, KAKENHI-PROJECT-15K18823, KAKENHI-PUBLICLY-16H01226, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-16H06161
  • [Journal Article] Nucleolus precursor body (NPB): A distinct structure in mammalian oocytes and zygotes2014

    • Author(s)
      Kyogoku H, Kitajima TS, Miyano T
    • Journal Title

      Nucleus

      Volume: 5(6) Issue: 6 Pages: 493-498

    • DOI

      10.4161/19491034.2014.990858

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25660253, KAKENHI-PROJECT-26292136, KAKENHI-PROJECT-26650072
  • [Presentation] 初期胚の染色体分配異常発生メカニズム2024

    • Author(s)
      京極 博久
    • Organizer
      第65回日本卵子学会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-22H04674
  • [Presentation] The source of chromosome abnormalities in early embryos2023

    • Author(s)
      京極 博久
    • Organizer
      BDR symposium 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-22H04674
  • [Presentation] 初期胚の染色体分配はなぜ不安定なのか?2023

    • Author(s)
      京極 博久
    • Organizer
      第116回 日本繁殖生物学会大会
    • Data Source
      KAKENHI-PUBLICLY-22H04674
  • [Presentation] 哺乳類受精卵における前核サイズの制御とその意味2021

    • Author(s)
      京極博久, 多羅間充輔, 柴田達夫, 北島智也
    • Organizer
      日本分子生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-20H05376
  • [Presentation] Competition-based scaling of two pronuclei enables epigenetic maintenance in zygotes2021

    • Author(s)
      Hirohisa Kyogoku, Mitsusuke Tarama, Tappei Mishina, Tatsuo Shibata, Tomoya S Kitajima
    • Organizer
      RIKEN BDR Symposium 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-20H05376
  • [Presentation] 初期受精卵における競合する前核のサイズによるヒストンメチル化制御2021

    • Author(s)
      多羅間充輔, 京極博久, 柴田達夫, 北島智也
    • Organizer
      日本物理学会
    • Data Source
      KAKENHI-PUBLICLY-20H05376
  • [Presentation] 受精卵における雌雄前核のサイズ差が適切なヒストンメチル化修飾を制御している2021

    • Author(s)
      京極 博久,多羅間 充輔,三品 達平,柴田 達夫,北島 智也
    • Organizer
      日本繁殖生物学会
    • Data Source
      KAKENHI-PUBLICLY-20H05376
  • [Presentation] Competition-based scaling of two pronuclei enables epigenetic maintenance in zygotes2021

    • Author(s)
      Hirohisa Kyogoku, Mitsusuke Tarama, Tappei Mishina, Tatsuo Shibata, Tomoya S Kitajima
    • Organizer
      RIKEN BDR Symposium 2021「Structuring biosystems: Functions emerging from molecules」
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-20H05376
  • [Presentation] 受精卵の核サイズによるヒストンメチル化修飾制御機構の解明2020

    • Author(s)
      京極 博久
    • Organizer
      新学術領域研究 『配偶子インテグリティの構築』『全能性プログラム』 合同公開シンポジウム
    • Data Source
      KAKENHI-PUBLICLY-20H05376
  • [Presentation] 受精卵の核サイズによるヒストンメチル化修飾制御2020

    • Author(s)
      京極 博久, 北島 智也
    • Organizer
      第113回 日本繁殖生物学会大会
    • Data Source
      KAKENHI-PUBLICLY-20H05376
  • [Presentation] 受精卵における二つの前核形成の意義2020

    • Author(s)
      北島智也, 京極博久
    • Organizer
      第65回日本生殖医学会
    • Data Source
      KAKENHI-PUBLICLY-20H05376
  • [Presentation] 受精卵における核サイズによるヒストンメチル化修飾の制御2020

    • Author(s)
      京極 博久
    • Organizer
      日本遺伝学会第92回大会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-20H05376
  • [Presentation] Cytoplasmic size modulates kinetochore-microtubule stability in early embryonic development2019

    • Author(s)
      京極博久
    • Organizer
      第2 回 新学術領域研究「配偶子インテグリティの構築」領域会議
    • Data Source
      KAKENHI-PROJECT-19K15811
  • [Presentation] 卵母細胞は大きな細胞質のために染色体分配異常を起こしやすい2016

    • Author(s)
      京極 博久
    • Organizer
      第109回日本繁殖生物学会大会
    • Place of Presentation
      麻布大学(神奈川県相模原市)
    • Year and Date
      2016-09-13
    • Data Source
      KAKENHI-PROJECT-15K18823
  • [Presentation] Effects of oocyte size on chromosome segregation during meiosis2016

    • Author(s)
      Kyogoku H. and Kitajima T.S.
    • Organizer
      Meiosis: Gordon Research Conference
    • Place of Presentation
      Colby-Sawyer College (米国New London)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26650072
  • [Presentation] Large cytoplasmic size is linked to the error-prone nature of oocytes2016

    • Author(s)
      Hirohisa Kyogoku, Tomoya S Kitajima
    • Organizer
      CDB symposium 2016 Size in Development
    • Place of Presentation
      RIKEN Center for Developmental Biology (Kobe, Japan)
    • Year and Date
      2016-03-29
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18823
  • [Presentation] 卵母細胞の紡錘体チェックポイントは、なぜ弱いのか?2015

    • Author(s)
      京極博久、北島智也
    • Organizer
      第108回日本繁殖生物学会大会
    • Place of Presentation
      宮崎大学 (宮崎県・宮崎市)
    • Year and Date
      2015-09-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18823
  • [Presentation] The cytoplasmic volume controls the spindle size and checkpoint in oocytes2015

    • Author(s)
      Hirohisa Kyogoku, Tomoya S Kitajima
    • Organizer
      The 26th CDB meeting Mechanistic Perspectives of Multicellular Organization
    • Place of Presentation
      RIKEN Center for Developmental Biology (Kobe, Japan)
    • Year and Date
      2015-09-08
    • Data Source
      KAKENHI-PROJECT-15K18823
  • [Presentation] 卵母細胞では細胞質の体積が紡錘体チェックポイントの強さに影響する2015

    • Author(s)
      京極博久、北島智也
    • Organizer
      BMB2015 (第38回日本分子生物学会年会、第88回日本生化学会大会合同大会)
    • Place of Presentation
      神戸ポートアイランド (兵庫県・神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15K18823
  • 1.  Kitajima Tomoya (00376641)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 2.  宮野 隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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