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Inoue Masanori  井上 真紀

ORCIDConnect your ORCID iD *help
Researcher Number 20726913
Other IDs
Affiliation (Current) 2025: 大分大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2022 – 2025: 大分大学, 医学部, 講師
2020 – 2021: 大分大学, 医学部, 助教
2019: 大分大学, 医学部, 医員
Review Section/Research Field
Principal Investigator
Basic Section 52050:Embryonic medicine and pediatrics-related
Except Principal Investigator
Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 58070:Lifelong developmental nursing-related
Keywords
Principal Investigator
ゼブラフィッシュ / マウス / オートファジー / 急性肝不全 / LARS1 / 乳児肝不全症候群1型 / 神経変性疾患 / RNA代謝 / 橋小脳低形成 / PKM2 … More / p53 / 神経細胞死 / tRNA fragment / 橋小脳低形成10型 … More
Except Principal Investigator
ゼブラフィッシュ / オートファジー / 難聴 / ゼブラフィッシュXLMTMモデル / ライトシート型超解像顕微鏡 / 生体ライブイメージング / 重度肝障害 / MTM1遺伝子 / 疾患モデル動物 / イメージング解析 / 肝障害 / MTM1遺伝子 / X連鎖性ミオチュブラーミオパチー / 早老症 / 遠位尿細管アシドーシス / 細胞内代謝 / 機能獲得型変異 / 免疫疲弊 / 解糖系 / SLE / PIK3CD / pH / リソソーム / 遠位尿細管性アシドーシス / 遺伝子変異率 / MELAS / ミトコンドリア / 脳卒中様エピソード / ヘテロプラスミー / ミトコンドリア病 Less
  • Research Projects

    (10 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (15 People)
  •  乳児肝不全症候群1型における炎症増悪機序と治療標的の解明Principal Investigator

    • Principal Investigator
      井上 真紀
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Oita University
  •  ゼブラフィッシュatp6v1ba遺伝子変異による耳石形成障害と難聴の機序解明

    • Principal Investigator
      池内 真代
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Oita University
  •  Environmental factors under autophagy regulation causing the development of Hutchinson-Gilford progeria syndrome

    • Principal Investigator
      井原 健二
    • Project Period (FY)
      2024 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Oita University
  •  臨床的意義不明の変化と判定された小児と保護者への遺伝カウンセリング体制の構築

    • Principal Investigator
      小栗 沙織
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58070:Lifelong developmental nursing-related
    • Research Institution
      Oita University
  •  X連鎖性ミオチュブラーミオパチーに合併する肝紫斑病の病態メカニズムの解明

    • Principal Investigator
      清水 誠之
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Oita University
  •  乳児肝不全症候群1型における乳児期重症化と発熱時増悪因子の解明Principal Investigator

    • Principal Investigator
      井上 真紀
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Oita University
  •  Elucidation of the mechanism of hearing loss associated with distal tubular acidosis

    • Principal Investigator
      Ikeuchi Mayo
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Oita University
  •  新規PIK3CD遺伝子変異によるSLE発症機構を解明する

    • Principal Investigator
      清田 今日子
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Oita University
  •  Mitochondria function analysis using autopsied brain samples of MELAS

    • Principal Investigator
      宮原 弘明
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Aichi Medical University
  •  Physiological and pathological significance of tRNA fragments in hereditary neurodegenerative diseasesPrincipal Investigator

    • Principal Investigator
      Inoue Masanori
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Oita University

All 2024 2023 2022 2020 2019

All Journal Article Presentation

  • [Journal Article] Cardiac manifestations of human ACTA2 variants recapitulated in a zebrafish model2024

    • Author(s)
      Sebastian Wulan Apridita、Inoue Masanori、Shimizu Nobuyuki、Sato Ryosuke、Oguri Saori、Itonaga Tomoyo、Kishimoto Shintaro、Shiraishi Hiroshi、Hanada Toshikatsu、Ihara Kenji
    • Journal Title

      Journal of Human Genetics

      Volume: 69 Issue: 3-4 Pages: 133-138

    • DOI

      10.1038/s10038-024-01221-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K07336, KAKENHI-PROJECT-20H03644
  • [Journal Article] A pH imbalance is linked to autophagic dysregulation of inner ear hair cells in Atp6v1ba-deficient zebrafish2024

    • Author(s)
      Ikeuchi Mayo、Inoue Masanori、Miyahara Hiroaki、Sebastian Wulan Apridita、Miyazaki Shuya、Takeno Takashi、Kiyota Kyoko、Yano Shinji、Shiraishi Hiroshi、Shimizu Nobuyuki、Hanada Reiko、Yoshimura Akihiko、Ihara Kenji、Hanada Toshikatsu
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 699 Pages: 149551-149551

    • DOI

      10.1016/j.bbrc.2024.149551

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K07336, KAKENHI-PROJECT-21K06871, KAKENHI-PROJECT-21K07756, KAKENHI-PROJECT-20H03644, KAKENHI-PROJECT-23K21629
  • [Journal Article] Tyrosine pre-transfer RNA fragments are linked to p53-dependent neuronal cell death via PKM22020

    • Author(s)
      Inoue Masanori、Hada Kazumasa、Shiraishi Hiroshi、Yatsuka Hiroyuki、Fujinami Hiroyuki、Morisaki Ikuko、Nishida Yoshihiro、Matsubara Etsuro、Ishitani Tohru、Hanada Reiko、Matsumoto Masaki、Penninger Josef M.、Ihara Kenji、Hanada Toshikatsu
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: May 3 Issue: 3 Pages: 155-163

    • DOI

      10.1016/j.bbrc.2020.02.157

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22973, KAKENHI-PROJECT-19K17366, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-16H05154, KAKENHI-PROJECT-19H03566, KAKENHI-PROJECT-16K11096, KAKENHI-PROJECT-17K19919, KAKENHI-PROJECT-18K19522, KAKENHI-PROJECT-17K15623, KAKENHI-PROJECT-20K21502, KAKENHI-PROJECT-19H03412, KAKENHI-PROJECT-20H03644, KAKENHI-PROJECT-18K06963, KAKENHI-PROJECT-18K08522, KAKENHI-PLANNED-20H05930
  • [Presentation] X連鎖性ミオチュブラーミオパチーに伴う重度肝障害の病態メカニズム2024

    • Author(s)
      清水 誠之, 白石 裕士, 井上 真紀, 清田 今日子, 井原 健二, 花田 俊勝
    • Organizer
      第101回 日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-23K07336
  • [Presentation] X連鎖性ミオチュブラーミオパチーに伴う重度肝障害の分子メカニズムの解明2023

    • Author(s)
      清水 誠之, 白石 裕士, 井上 真紀, 清田 今日子, 井原 健二, 花田 俊勝
    • Organizer
      第96回 日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-23K07336
  • [Presentation] Autophagy enhancement induces steatosis in the developing liver of lars-knock-in zebrafish2023

    • Author(s)
      Masanori Inoue, Wulan Apridita Sebastian, Hiroaki Miyahara, Nobuyuki Shimizu, Hiroshi Shiraishi, Miwako Maeda, Reiko Hanada, Toshikatsu Hanada, Kenji Ihara
    • Organizer
      Human Genetics Asia 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15947
  • [Presentation] ゼブラフィッシュイメージングを用いたX連鎖性ミオチュブラーミオパチーに合併する重度肝障害の病態機構解明2023

    • Author(s)
      清水 誠之, 白石 裕士, 井上 真紀, 清田 今日子, 井原 健二, 花田 俊勝
    • Organizer
      第13回 癌・炎症と抗酸化研究会プログラム(CIA研究会)
    • Data Source
      KAKENHI-PROJECT-23K07336
  • [Presentation] Analysis of the liver damage mechanism in infantile liver failure syndrome type 1 using lars knock-in zebrafish.2022

    • Author(s)
      Masanori Inoue, Kazuhito Sekiguchi, Hiroaki Miyahara, Shota Sonoda, Nobuyuki Shimizu, Hiroshi Shiraishi, Miwako Maeda, Reiko Hanada, Toshikatsu Hanada, Kenji Ihara
    • Organizer
      日本人類遺伝学会第67回大会
    • Data Source
      KAKENHI-PROJECT-22K15947
  • [Presentation] tRNA代謝異常によるp53依存的神経細胞死の分子機構解明2019

    • Author(s)
      井上 真紀, 波田 一誠, 白石 裕士, 石谷 太, 松本 雅記, 井原 健二, 花田 俊勝
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-19K17366
  • 1.  Ikeuchi Mayo (80865668)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  井原 健二 (80294932)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  清田 今日子 (30774492)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  Sebastian WulanApridita (60979540)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  宮原 弘明 (00457615)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  吉田 眞理 (60288545)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  岩崎 靖 (60378172)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  関口 和人 (40437926)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  花田 俊勝 (10363350)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  松尾 宗明 (20219398)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  小崎 里華 (50234745)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  小栗 沙織 (00993106)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  清水 誠之 (30817143)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 14.  西田 欣広
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  井上 尚実
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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