Inoue Masanori 井上真紀

Researcher Number	20726913
Other IDs
Affiliation (Current)	2025: 大分大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2022 – 2025: 大分大学, 医学部, 講師 2020 – 2021: 大分大学, 医学部, 助教 2019: 大分大学, 医学部, 医員
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 58070:Lifelong developmental nursing-related
Keywords	Principal Investigator ゼブラフィッシュ / マウス / オートファジー / 急性肝不全 / LARS1 / 乳児肝不全症候群1型 / 神経変性疾患 / RNA代謝 / 橋小脳低形成 / PKM2 … More / p53 / 神経細胞死 / tRNA fragment / 橋小脳低形成10型 … More Except Principal Investigator ゼブラフィッシュ / オートファジー / 難聴 / ゼブラフィッシュXLMTMモデル / ライトシート型超解像顕微鏡 / 生体ライブイメージング / 重度肝障害 / ＭＴＭ１遺伝子 / 疾患モデル動物 / イメージング解析 / 肝障害 / MTM1遺伝子 / X連鎖性ミオチュブラーミオパチー / 早老症 / 遠位尿細管アシドーシス / 細胞内代謝 / 機能獲得型変異 / 免疫疲弊 / 解糖系 / SLE / PIK3CD / pH / リソソーム / 遠位尿細管性アシドーシス / 遺伝子変異率 / MELAS / ミトコンドリア / 脳卒中様エピソード / ヘテロプラスミー / ミトコンドリア病 Less

乳児肝不全症候群1型における炎症増悪機序と治療標的の解明Principal Investigator
- Principal Investigator
  
  井上真紀
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Oita University
ゼブラフィッシュatp6v1ba遺伝子変異による耳石形成障害と難聴の機序解明
- Principal Investigator
  
  池内真代
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Oita University
Environmental factors under autophagy regulation causing the development of Hutchinson-Gilford progeria syndrome
- Principal Investigator
  
  井原健二
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Oita University
臨床的意義不明の変化と判定された小児と保護者への遺伝カウンセリング体制の構築
- Principal Investigator
  
  小栗沙織
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58070:Lifelong developmental nursing-related
- Research Institution
  Oita University
X連鎖性ミオチュブラーミオパチーに合併する肝紫斑病の病態メカニズムの解明
- Principal Investigator
  
  清水誠之
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Oita University
乳児肝不全症候群1型における乳児期重症化と発熱時増悪因子の解明Principal Investigator
- Principal Investigator
  
  井上真紀
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Oita University
Elucidation of the mechanism of hearing loss associated with distal tubular acidosis
- Principal Investigator
  
  Ikeuchi Mayo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Oita University
新規PIK3CD遺伝子変異によるSLE発症機構を解明する
- Principal Investigator
  
  清田今日子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Oita University
Mitochondria function analysis using autopsied brain samples of MELAS
- Principal Investigator
  
  宮原弘明
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Aichi Medical University
Physiological and pathological significance of tRNA fragments in hereditary neurodegenerative diseasesPrincipal Investigator
- Principal Investigator
  
  Inoue Masanori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Oita University

All 2024 2023 2022 2020 2019

All Journal Article Presentation

[Journal Article] Cardiac manifestations of human ACTA2 variants recapitulated in a zebrafish model2024
- Author(s)
  Sebastian Wulan Apridita、Inoue Masanori、Shimizu Nobuyuki、Sato Ryosuke、Oguri Saori、Itonaga Tomoyo、Kishimoto Shintaro、Shiraishi Hiroshi、Hanada Toshikatsu、Ihara Kenji
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 69 Issue: 3-4 Pages: 133-138
- DOI
  10.1038/s10038-024-01221-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07336, KAKENHI-PROJECT-20H03644
[Journal Article] A pH imbalance is linked to autophagic dysregulation of inner ear hair cells in Atp6v1ba-deficient zebrafish2024
- Author(s)
  Ikeuchi Mayo、Inoue Masanori、Miyahara Hiroaki、Sebastian Wulan Apridita、Miyazaki Shuya、Takeno Takashi、Kiyota Kyoko、Yano Shinji、Shiraishi Hiroshi、Shimizu Nobuyuki、Hanada Reiko、Yoshimura Akihiko、Ihara Kenji、Hanada Toshikatsu
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 699 Pages: 149551-149551
- DOI
  10.1016/j.bbrc.2024.149551
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K07336, KAKENHI-PROJECT-21K06871, KAKENHI-PROJECT-21K07756, KAKENHI-PROJECT-20H03644, KAKENHI-PROJECT-23K21629
[Journal Article] Tyrosine pre-transfer RNA fragments are linked to p53-dependent neuronal cell death via PKM22020
- Author(s)
  Inoue Masanori、Hada Kazumasa、Shiraishi Hiroshi、Yatsuka Hiroyuki、Fujinami Hiroyuki、Morisaki Ikuko、Nishida Yoshihiro、Matsubara Etsuro、Ishitani Tohru、Hanada Reiko、Matsumoto Masaki、Penninger Josef M.、Ihara Kenji、Hanada Toshikatsu
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: May 3 Issue: 3 Pages: 155-163
- DOI
  10.1016/j.bbrc.2020.02.157
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22973, KAKENHI-PROJECT-19K17366, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-16H05154, KAKENHI-PROJECT-19H03566, KAKENHI-PROJECT-16K11096, KAKENHI-PROJECT-17K19919, KAKENHI-PROJECT-18K19522, KAKENHI-PROJECT-17K15623, KAKENHI-PROJECT-20K21502, KAKENHI-PROJECT-19H03412, KAKENHI-PROJECT-20H03644, KAKENHI-PROJECT-18K06963, KAKENHI-PROJECT-18K08522, KAKENHI-PLANNED-20H05930
[Presentation] X連鎖性ミオチュブラーミオパチーに伴う重度肝障害の病態メカニズム2024
- Author(s)
  清水誠之, 白石裕士, 井上真紀, 清田今日子, 井原健二, 花田俊勝
- Organizer
  第101回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-23K07336
[Presentation] X連鎖性ミオチュブラーミオパチーに伴う重度肝障害の分子メカニズムの解明2023
- Author(s)
  清水誠之, 白石裕士, 井上真紀, 清田今日子, 井原健二, 花田俊勝
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K07336
[Presentation] Autophagy enhancement induces steatosis in the developing liver of lars-knock-in zebrafish2023
- Author(s)
  Masanori Inoue, Wulan Apridita Sebastian, Hiroaki Miyahara, Nobuyuki Shimizu, Hiroshi Shiraishi, Miwako Maeda, Reiko Hanada, Toshikatsu Hanada, Kenji Ihara
- Organizer
  Human Genetics Asia 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15947
[Presentation] ゼブラフィッシュイメージングを用いたX連鎖性ミオチュブラーミオパチーに合併する重度肝障害の病態機構解明2023
- Author(s)
  清水誠之, 白石裕士, 井上真紀, 清田今日子, 井原健二, 花田俊勝
- Organizer
  第13回癌・炎症と抗酸化研究会プログラム（CIA研究会）
- Data Source
  KAKENHI-PROJECT-23K07336
[Presentation] Analysis of the liver damage mechanism in infantile liver failure syndrome type 1 using lars knock-in zebrafish.2022
- Author(s)
  Masanori Inoue, Kazuhito Sekiguchi, Hiroaki Miyahara, Shota Sonoda, Nobuyuki Shimizu, Hiroshi Shiraishi, Miwako Maeda, Reiko Hanada, Toshikatsu Hanada, Kenji Ihara
- Organizer
  日本人類遺伝学会第67回大会
- Data Source
  KAKENHI-PROJECT-22K15947
[Presentation] tRNA代謝異常によるp53依存的神経細胞死の分子機構解明2019
- Author(s)
  井上真紀, 波田一誠, 白石裕士, 石谷太, 松本雅記, 井原健二, 花田俊勝
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K17366

1. Ikeuchi Mayo (80865668)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 井原健二 (80294932)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 清田今日子 (30774492)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Sebastian WulanApridita (60979540)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 宮原弘明 (00457615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 吉田眞理 (60288545)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 岩崎靖 (60378172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 関口和人 (40437926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 花田俊勝 (10363350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 松尾宗明 (20219398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 小崎里華 (50234745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 小栗沙織 (00993106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 清水誠之 (30817143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
14. 西田欣広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 井上尚実

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Inoue Masanori 井上 真紀

Research Projects

Research Products

Co-Researchers

乳児肝不全症候群1型における炎症増悪機序と治療標的の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ゼブラフィッシュatp6v1ba遺伝子変異による耳石形成障害と難聴の機序解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Environmental factors under autophagy regulation causing the development of Hutchinson-Gilford progeria syndrome

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

臨床的意義不明の変化と判定された小児と保護者への遺伝カウンセリング体制の構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

X連鎖性ミオチュブラーミオパチーに合併する肝紫斑病の病態メカニズムの解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

乳児肝不全症候群1型における乳児期重症化と発熱時増悪因子の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism of hearing loss associated with distal tubular acidosis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新規PIK3CD遺伝子変異によるSLE発症機構を解明する

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mitochondria function analysis using autopsied brain samples of MELAS

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Physiological and pathological significance of tRNA fragments in hereditary neurodegenerative diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Cardiac manifestations of human ACTA2 variants recapitulated in a zebrafish model2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A pH imbalance is linked to autophagic dysregulation of inner ear hair cells in Atp6v1ba-deficient zebrafish2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tyrosine pre-transfer RNA fragments are linked to p53-dependent neuronal cell death via PKM22020

Author(s)

Journal Title

DOI

Data Source

[Presentation] X連鎖性ミオチュブラーミオパチーに伴う重度肝障害の病態メカニズム2024

Inoue Masanori 井上真紀