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Natsubori Akiyo  夏堀 晃世

… Alternative Names

夏堀 晃世  ナツボリ アキヨ

NATSUBORI Akiyo  夏堀 晃世

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Researcher Number 20732837
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-6401-4469
Affiliation (Current) 2025: 公益財団法人東京都医学総合研究所, 精神行動医学研究分野, 主席研究員
2025: 公益財団法人東京都医学総合研究所, 臨床医科学研究分野, 主席研究員
Affiliation (based on the past Project Information) *help 2021 – 2023: 公益財団法人東京都医学総合研究所, 精神行動医学研究分野, 主席研究員
2016 – 2019: 公益財団法人東京都医学総合研究所, 精神行動医学研究分野, 主席研究員
Review Section/Research Field
Principal Investigator
Basic Section 46030:Function of nervous system-related / Transformative Research Areas, Section (III) / Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / Environmental physiology(including physical medicine and nutritional physiology)
Keywords
Principal Investigator
ファイバフォトメトリー / ATP / 睡眠 / インビボ計測 / in vivo / 睡眠覚醒 / 空間記憶 / 光遺伝学 / 海馬 / 脳血流 … More / 脳代謝 / 乳酸シャトル / オプトジェネティクス / アストロサイト / セロトニン神経 / オレキシン神経 / アデノシン3リン酸 (ATP) / アデノシン3リン酸 / 生体計測 / アデノシン三リン酸 / 生体脳計測 / アデノシン3リン酸 (ATP) / 代謝 / 神経科学 / 脳・神経 / In vivo / 脳 / 細胞内ATP / アデノシン3リン酸(ATP) / 大脳皮質 / アデノシン三リン酸(ATP) Less
  • Research Projects

    (4 results)
  • Research Products

    (33 results)
  • Co-Researchers

    (5 People)
  •  神経細胞内ATPによる神経活動と脳機能の調節機構の検証Principal Investigator

    • Principal Investigator
      夏堀 晃世
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 46030:Function of nervous system-related
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  セロトニン神経とアストロサイト代謝ネットワークによるエネルギー恒常性維持の解明Principal Investigator

    • Principal Investigator
      夏堀 晃世
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Cellular energy dynamics in orexin neurons across sleep-wake cyclePrincipal Investigator

    • Principal Investigator
      NATSUBORI Akiyo
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Study for brain cellular energy dynamics across sleep-wake cyclePrincipal Investigator

    • Principal Investigator
      NATSUBORI Akiyo
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Environmental physiology(including physical medicine and nutritional physiology)
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science

All 2024 2023 2022 2021 2019 2018 2017

All Journal Article Presentation Book

  • [Book] 睡眠医療2021

    • Author(s)
      夏堀 晃世
    • Total Pages
      4
    • Publisher
      株式会社 ライフ・サイエンス
    • ISBN
      9784898017166
    • Data Source
      KAKENHI-PUBLICLY-21H05641
  • [Journal Article] Serotonergic regulation of cortical neurovascular coupling and hemodynamics upon awakening from sleep in mice2024

    • Author(s)
      Natsubori A., Kwon S., Honda Yoshiko., Kojima T., Karashima A., Masamoto K., Honda M.
    • Journal Title

      Journal of Cerebral Blood Flow & Metabolism

      Volume: - Issue: 9 Pages: 1591-1607

    • DOI

      10.1177/0271678x241238843

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K12811, KAKENHI-PROJECT-23K06009
  • [Journal Article] Immediate glucose signaling transmitted via the vagus nerve in gut-brain neural communication2024

    • Author(s)
      Serika Yamada, Akiyo Natsubori, Kazuki Harada, Takashi Tsuboi, Hiromu Monai
    • Journal Title

      bioRxiv

      Volume: -

    • DOI

      10.1101/2024.03.27.586971

    • Open Access
    • Data Source
      KAKENHI-PROJECT-23K06009
  • [Journal Article] Serotonergic neurons control cortical neuronal intracellular energy dynamics by modulating astrocyte-neuron lactate shuttle2023

    • Author(s)
      Natsubori Akiyo、Hirai Shinobu、Kwon Soojin、Ono Daisuke、Deng Fei、Wan Jinxia、Miyazawa Momoka、Kojima Takashi、Okado Haruo、Karashima Akihiro、Li Yulong、Tanaka Kenji F.、Honda Makoto
    • Journal Title

      iScience

      Volume: 26 Issue: 1 Pages: 105830-105830

    • DOI

      10.1016/j.isci.2022.105830

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K12811, KAKENHI-PROJECT-20KK0177, KAKENHI-PLANNED-20H05896, KAKENHI-PUBLICLY-21H05641, KAKENHI-PROJECT-21H02526, KAKENHI-PROJECT-22KF0166, KAKENHI-PROJECT-21K19255, KAKENHI-PROJECT-18H02537, KAKENHI-PUBLICLY-21H00307, KAKENHI-PUBLICLY-21H00422, KAKENHI-PROJECT-23K23992
  • [Journal Article] Dopamine Receptor Type 2-Expressing Medium Spiny Neurons in the Ventral Lateral Striatum Have a Non-REM Sleep-Induce Function2023

    • Author(s)
      Tomonobu Kato, Kenji F. Tanaka, Akiyo Natsubori
    • Journal Title

      eNeuro

      Volume: 10 Issue: 9 Pages: ENEURO.0327-23.2023

    • DOI

      10.1523/eneuro.0327-23.2023

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K06009
  • [Journal Article] アストロサイトのエネルギー代謝調節機能と役割2022

    • Author(s)
      夏堀 晃世
    • Journal Title

      Farumashia

      Volume: 58 Issue: 9 Pages: 877-881

    • DOI

      10.14894/faruawpsj.58.9_877

    • ISSN
      0014-8601, 2189-7026
    • Language
      Japanese
    • Data Source
      KAKENHI-PUBLICLY-21H05641
  • [Journal Article] Region-specific involvement of ventral striatal dopamine D2 receptor-expressing medium spiny neurons in nociception.2022

    • Author(s)
      Natsubori, A, Miyazawa, M., Kojima, T., Honda, M.
    • Journal Title

      Neuroscience Research

      Volume: 22 Pages: 00298-00298

    • DOI

      10.1016/j.neures.2022.12.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-21H05641
  • [Journal Article] The Mlc1 Promoter Directs M?ller Cell-specific Gene Expression in the Retina2022

    • Author(s)
      Danjo Yosuke、Shinozaki Youichi、Natsubori Akiyo、Kubota Yuto、Kashiwagi Kenji、Tanaka Kenji F.、Koizumi Schuichi
    • Journal Title

      Translational Vision Science & Technology

      Volume: 11 Issue: 1 Pages: 25-25

    • DOI

      10.1167/tvst.11.1.25

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06481, KAKENHI-PUBLICLY-21H05641, KAKENHI-PROJECT-20K09786, KAKENHI-PROJECT-20KK0366, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-22H04922, KAKENHI-PLANNED-20H05896, KAKENHI-PLANNED-20H05902, KAKENHI-PROJECT-21H04786
  • [Journal Article] FoxG1 regulates the formation of cortical GABAergic circuit during an early postnatal critical period resulting in autism spectrum disorder-like phenotypes2021

    • Author(s)
      Miyoshi Goichi、Ueta Yoshifumi、Natsubori Akiyo、Hiraga Kou、Osaki Hironobu、Yagasaki Yuki、Kishi Yusuke、Yanagawa Yuchio、Fishell Gord、Machold Robert P、Miyata Mariko
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 3773-3773

    • DOI

      10.1038/s41467-021-23987-z

    • NAID

      120007125060

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04789, KAKENHI-PUBLICLY-19H05228, KAKENHI-PROJECT-21K15634, KAKENHI-PUBLICLY-20H05383, KAKENHI-PUBLICLY-21H00242, KAKENHI-PUBLICLY-21H05641, KAKENHI-PROJECT-20H03179, KAKENHI-PROJECT-19H03343, KAKENHI-PROJECT-16H06279, KAKENHI-ORGANIZER-20H05914
  • [Journal Article] Logistics Mechanisms Involved in Maintaining Energy Homeostasis in the Brain2021

    • Author(s)
      夏堀 晃世
    • Journal Title

      The Brain & Neural Networks

      Volume: 28 Issue: 2 Pages: 87-92

    • DOI

      10.3902/jnns.28.87

    • NAID

      130008062344

    • ISSN
      1340-766X, 1883-0455
    • Year and Date
      2021-06-05
    • Language
      Japanese
    • Open Access
    • Data Source
      KAKENHI-PUBLICLY-21H05641
  • [Journal Article] Neuroimaging correlates of narcolepsy with cataplexy: A systematic review.2019

    • Author(s)
      Wada M, Mimura M, Noda Y, Takasu S, Plitman E, Honda M, Natsubori A, Ogyu K, Tarumi R, Graff-Guerrero A, Nakajima S.
    • Journal Title

      Neurosci Res.

      Volume: 142 Pages: 16-29

    • DOI

      10.1016/j.neures.2018.03.005

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14756
  • [Journal Article] Ventrolateral striatal medium spiny neurons positively regulate food-incentive, goal-directed behavior independently of D1 and D2 selectivity.2017

    • Author(s)
      Akiyo Natsubori, Iku Tsustui-Kimura, Hiroshi Nishida, Youcef Bouchekioua, Hiroshi Sekiya, Motokazu Uchigashima, Masahiko Watanabe, Alban de Kerchove d'Exaerde, Masaru Mimura, Norio Takata, and Kenji Tanaka
    • Journal Title

      Journal of Neuroscience

      Volume: 37 Issue: 10 Pages: 2723-2733

    • DOI

      10.1523/jneurosci.3377-16.2017

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01620, KAKENHI-PUBLICLY-16H01621, KAKENHI-PLANNED-25117005, KAKENHI-PROJECT-24220007, KAKENHI-PROJECT-15H03123, KAKENHI-PROJECT-14J40100, KAKENHI-PROJECT-26460335, KAKENHI-PROJECT-15K06732, KAKENHI-PROJECT-15KT0111, KAKENHI-PROJECT-16K07032, KAKENHI-PROJECT-16K19009, KAKENHI-PUBLICLY-17H06062
  • [Journal Article] Distinct Roles of Ventromedial versus Ventrolateral Striatal Medium Spiny Neurons in Reward-Oriented Behavior.2017

    • Author(s)
      Tsutsui-Kimura I, Natsubori A, Mori M, Kobayashi K, Drew MR, de Kerchove d'Exaerde A, Mimura M, Tanaka KF.
    • Journal Title

      Curr Biol

      Volume: 27 Issue: 19 Pages: 3042-3048

    • DOI

      10.1016/j.cub.2017.08.061

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01621, KAKENHI-PUBLICLY-17H06062, KAKENHI-PLANNED-25117005, KAKENHI-PROJECT-15H03123, KAKENHI-PROJECT-16K19009
  • [Presentation] 光遺伝学が切り拓く睡眠・脳代謝研究2024

    • Author(s)
      夏堀 晃世
    • Organizer
      レーザー学会学術講演会第44回年次大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K06009
  • [Presentation] 縫線核セロトニン神経による脳内エネルギー代謝調節機構2023

    • Author(s)
      夏堀 晃世
    • Organizer
      第100回 日本生理学会大会
    • Data Source
      KAKENHI-PUBLICLY-21H05641
  • [Presentation] 縫線核セロトニン神経の脳内エネルギー代謝調節機能2023

    • Author(s)
      夏堀 晃世
    • Organizer
      第97回日本薬理学会年会・第44回日本臨床薬理学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K06009
  • [Presentation] 縫線核セロトニン神経による脳内エネルギー代謝活動調節2023

    • Author(s)
      夏堀 晃世
    • Organizer
      日本睡眠学会第45回定期学術集会・第30回日本時間生物学会学術大会
    • Data Source
      KAKENHI-PROJECT-23K06009
  • [Presentation] セロトニン神経とアストロサイト代謝ネットワークによるエネルギー恒常性維持の解明2023

    • Author(s)
      夏堀 晃世
    • Organizer
      第5回グリアデコード領域会議
    • Data Source
      KAKENHI-PUBLICLY-21H05641
  • [Presentation] 睡眠覚醒に伴う脳のエネルギー代謝活動2023

    • Author(s)
      夏堀 晃世
    • Organizer
      脳の世紀推進会議 第31回脳の世紀シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K06009
  • [Presentation] セロトニン神経とアストロサイト代謝ネットワークによるエネルギー恒常性維持の解明2022

    • Author(s)
      夏堀 晃世
    • Organizer
      第4回グリアデコード領域会議
    • Data Source
      KAKENHI-PUBLICLY-21H05641
  • [Presentation] 睡眠覚醒に伴う脳内エネルギー代謝調節におけるセロトニン神経の役割2022

    • Author(s)
      夏堀 晃世
    • Organizer
      TOBIRA 第10回研究交流フォーラム
    • Data Source
      KAKENHI-PUBLICLY-21H05641
  • [Presentation] セロトニン神経調節下のアストロサイトによる脳内エネルギー代謝調節機構2022

    • Author(s)
      夏堀 晃世
    • Organizer
      第45回 日本分子生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-21H05641
  • [Presentation] 睡眠覚醒に伴う神経細胞内ATP動態とそれを支える脳のエネルギー代謝活動2021

    • Author(s)
      夏堀 晃世
    • Organizer
      日本睡眠学会 第46回定期学術集会
    • Data Source
      KAKENHI-PUBLICLY-21H05641
  • [Presentation] Intracellular ATP levels in mouse cortical excitatory neurons varies with sleep-wake states2021

    • Author(s)
      夏堀 晃世
    • Organizer
      日本睡眠学会 第46回定期学術集会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-21H05641
  • [Presentation] State-dependent regulation of cortical neuronal ATP dynamics2021

    • Author(s)
      Akiyo Natsubori
    • Organizer
      第44回 日本神経科学大会
    • Data Source
      KAKENHI-PUBLICLY-21H05641
  • [Presentation] In vivo dynamics of cortical neuronal intracellular ATP levels.2019

    • Author(s)
      夏堀 晃世
    • Organizer
      Optogenetics2019
    • Data Source
      KAKENHI-PROJECT-18K14756
  • [Presentation] In vivo optical recording reveal state-dependent intracellular ATP dynamics in neurons2019

    • Author(s)
      夏堀 晃世
    • Organizer
      第43回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-18K14756
  • [Presentation] 睡眠覚醒に伴う大脳皮質の細胞内ATP動態の解明2018

    • Author(s)
      夏堀 晃世
    • Organizer
      日本睡眠学会第43回定期学術集会
    • Data Source
      KAKENHI-PROJECT-18K14756
  • [Presentation] The intracellular ATP dynamics in the cerebral cortex is closely related to the neurometabolic coupling2018

    • Author(s)
      Akiyo Natsubori, Akihiro Karashima, Takashi Kojima, Toru Kodama, Kazuto Masamoto, Norio Takata, Kenji F Tanaka, Masamichi Yamamoto, Makoto Honda
    • Organizer
      Sapporo Symposium on Biological Rhythm in 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14756
  • [Presentation] 目的指向型行動における腹側線条体カルシウム振動の役割2017

    • Author(s)
      木村 生、夏堀 晃世、西田 洋司、田中 謙二
    • Organizer
      第94回日本生理学会大会
    • Place of Presentation
      アクトシティ浜松(静岡県浜松市)
    • Data Source
      KAKENHI-PROJECT-16K19009
  • [Presentation] 光ファイバ計測システムを用いたマウス脳の細胞内ATP動態計測.2017

    • Author(s)
      夏堀 晃世, 児玉 亨, 辛島 彰弘, 山本 正道, 高田 則雄, 田中 謙二, 本多 真.
    • Organizer
      第40回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-16K19009
  • [Presentation] 光ファイバを用いたマウス脳の細胞内ATP動態計測2017

    • Author(s)
      夏堀 晃世、児玉 亨、辛島 彰洋、山本 正道、高田 則雄、田中 謙二、本多 真
    • Organizer
      第94回日本生理学会大会
    • Place of Presentation
      アクトシティ浜松(静岡県浜松市)
    • Data Source
      KAKENHI-PROJECT-16K19009
  • [Presentation] 光ファイバを用いたマウス脳の細胞内ATP動態計測.2017

    • Author(s)
      夏堀 晃世, 児玉 亨, 辛島 彰弘, 山本 正道, 高田 則雄, 田中 謙二, 本多 真.
    • Organizer
      第94回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-16K19009
  • 1.  KARASHIMA Akihiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 2.  SHINOZAKI Youichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  三好 悟一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  高田 則雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  田中 謙二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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