sakakibara yasufumi 榊原泰史

… Alternative Names

Sakakibara Yasufumi 榊原泰史

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Researcher Number	20734099
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立長寿医療研究センター, 研究所認知症先進医療開発センター, 研究員
Affiliation (based on the past Project Information) *help	2023 – 2024: 国立研究開発法人国立長寿医療研究センター, 研究所認知症先進医療開発センター, 研究員 2022: 国立研究開発法人国立長寿医療研究センター, 研究所認知症先進医療開発センター, 特任研究員 2018 – 2021: 国立研究開発法人国立長寿医療研究センター, 認知症先進医療開発センター, 研究技術員
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 51030:Pathophysiologic neuroscience-related
Keywords	Principal Investigator ノルアドレナリン / 青斑核 / タウ病理 / 神経変性 / アルツハイマー病 / 軸索変性 / セロトニン神経系 / アミロイドβ病理 / 抑うつ症状 / 認知症 … More / 食事介入 / マウスモデル / 糖尿病 / WFS1 / 嗅内皮質 / アデノ随伴ウイルス Less

老年性認知症の抑うつ症状の原因となるセロトニン神経軸索変性の機序解明Principal Investigator
- Principal Investigator
  
  榊原泰史
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  National Center for Geriatrics and Gerontology
Elucidation of mechanisms underlying tau-mediated neurodegeneration by WFS1 deficiencyPrincipal Investigator
- Principal Investigator
  
  Sakakibara Yasufumi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  National Center for Geriatrics and Gerontology
Characterization of a novel genetic modifier of tau-mediated neurodegenerationPrincipal Investigator
- Principal Investigator
  
  Sakakibara Yasufumi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  National Center for Geriatrics and Gerontology

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Drosophila Toll-9 is induced by aging and neurodegeneration to modulate stress signaling and its deficiency exacerbates tau-mediated neurodegeneration2023
- Author(s)
  Sakakibara Yasufumi、Yamashiro Risa、Chikamatsu Sachie、Hirota Yu、Tsubokawa Yoko、Nishijima Risa、Takei Kimi、Sekiya Michiko、Iijima Koichi M.
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 2 Pages: 105968-105968
- DOI
  10.1016/j.isci.2023.105968
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K17655, KAKENHI-PROJECT-23K24224
[Journal Article] Alzheimer’s Disease-Related Phospho-Tau181 Signals Are Localized to Demyelinated Axons of Parvalbumin-Positive GABAergic Interneurons in an App Knock-In Mouse Model of Amyloid-β Pathology2023
- Author(s)
  Hirota Yu、Sakakibara Yasufumi、Takei Kimi、Nishijima Risa、Sekiya Michiko、Iijima Koichi M.
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 93 Issue: 3 Pages: 1065-1081
- DOI
  10.3233/jad-230121
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K17655, KAKENHI-PROJECT-23K24224
[Journal Article] Role for μ-opioid receptor in antidepressant effects of δ-opioid receptor agonist KNT-1272023
- Author(s)
  Moriya Yuki、Kasahara Yoshiyuki、Shimada Masafumi、Sakakibara Yasufumi、Fujii Hideaki、Nagase Hiroshi、Ide Soichiro、Ikeda Kazutaka、Hall F. Scott、Uhl George R.、Sora Ichiro
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 151 Issue: 3 Pages: 135-141
- DOI
  10.1016/j.jphs.2022.12.008
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06814, KAKENHI-PROJECT-21K17655, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-18K15532, KAKENHI-PROJECT-23K21457
[Journal Article] Distinct brain pathologies associated with Alzheimer’s disease biomarker-related phospho-tau 181 and phospho-tau 217 in <i>App</i> knock-in mouse models of amyloid-β amyloidosis2022
- Author(s)
  Hirota Yu、Sakakibara Yasufumi、Ibaraki Kyoko、Takei Kimi、Iijima Koichi M、Sekiya Michiko
- Journal Title
  
  Brain Communications
  
  Volume: 4 Issue: 6
- DOI
  10.1093/braincomms/fcac286
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K17655, KAKENHI-PROJECT-23K24224
[Journal Article] Widespread Reduced Density of Noradrenergic Locus Coeruleus Axons in the App Knock-In Mouse Model of Amyloid-β Amyloidosis2021
- Author(s)
  Yasufumi Sakakibara、Yu Hirota、Kyoko Ibaraki、Kimi Takei、Sachie Chikamatsu、Yoko Tsubokawa、Takashi Saito、Takaomi C. Saido、Michiko Sekiya、Koichi M. Iijima
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 82 Issue: 4 Pages: 1513-1530
- DOI
  10.3233/jad-210385
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K17655, KAKENHI-PROJECT-22KJ3205
[Journal Article] Repeated methamphetamine treatment increases spine density in the nucleus accumbens of serotonin transporter knockout mice2019
- Author(s)
  Yoshiyuki Kasahara、Yasufumi Sakakibara、Takashi Hiratsuka、Yuki Moriya、Klaus‐Peter Lesch、F. Scott Hall、George R. Uhl、Ichiro Sora
- Journal Title
  
  Neuropsychopharmacology Reports
  
  Volume: - Issue: 2 Pages: 1-4
- DOI
  10.1002/npr2.12049
- NAID
  120006996916
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15381, KAKENHI-PROJECT-18K15532, KAKENHI-PROJECT-16H06276
[Journal Article] Amyloid-β plaque formation and reactive gliosis are required for induction of cognitive deficits in App knock-in mouse models of Alzheimer's disease2019
- Author(s)
  Yasufumi Sakakibara、Michiko Sekiya、Takashi Saito、Takaomi C. Saido、Koichi M. Iijima
- Journal Title
  
  BMC Neuroscience
  
  Volume: 20 Issue: 1 Pages: 13-13
- DOI
  10.1186/s12868-019-0496-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15381, KAKENHI-PROJECT-16K08637
[Journal Article] Cognitive and emotional alterations in App knock-in mouse models of Aβ amyloidosis2018
- Author(s)
  Yasufumi Sakakibara、Michiko Sekiya、Takashi Saito、Takaomi C. Saido、Koichi M. Iijima
- Journal Title
  
  BMC Neuroscience
  
  Volume: 19 Issue: 1 Pages: 46-46
- DOI
  10.1186/s12868-018-0446-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15381, KAKENHI-PROJECT-16K08637
[Presentation] Mechanisms underlying reductions of serotonergic axon projections to the cortex in App knock-in mouse model of Aβ pathology2024
- Author(s)
  Sakakibara, Y., Hirota, Y., Ibaraki, K., Takei, K., Nishijima, R., Sekiya, M., Iijima, K.M.
- Organizer
  AD/PD2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] The delta opioid receptor activation and low mu opioid receptors expression interact to reduce depressive-like behavior2023
- Author(s)
  Moriya, Y., Kasahara, Y., Shimada, M., Sakakibara, Y., Fujii, H., Nagase, H., Ide, S., Ikeda, K., Hall, F.S., Uhl, G.R., Sora, I.
- Organizer
  34th CINP World Congress of Neuropsychopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] δオピオイド受容体作動薬KNT-127の抗うつ作用におけるμオピオイド受容体の役割2023
- Author(s)
  森屋由紀、笠原好之、嶋田政史、榊原泰史、藤井秀明、長瀬博、井手聡一郎、池田和隆、F.S. Hall、G.R. Uhl、曽良一郎
- Organizer
  第42回鎮痛薬・オピオイドペプチドシンポジウム
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] アルツハイマー病バイオマーカーリン酸化タウ181はパルブアルブミン陽性介在ニューロンの有髄軸索に局在する2023
- Author(s)
  廣田湧、榊原泰史、竹井喜美、西島里咲、関谷倫子、飯島浩一
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] 脳内のAβ病理を反映する血液・髄液バイオマーカーリン酸化タウの脳内局在解析2023
- Author(s)
  廣田湧、榊原泰史、茨木京子、竹井喜美、西島里咲、飯島浩一、関谷倫子
- Organizer
  第42回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] Biomarker-related phosphor-tau 181 signals localize to axons of myelinated neurons but not unmyelinated neurons in App knock-in mouse2023
- Author(s)
  Hirota, Y., Sakakibara, Y., Ibaraki, K., Takei, K., Nishijima, R., Takei, K., Sekiya, M., Iijima, K.M.
- Organizer
  AD/PD 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] Toll-like receptor exerts neuroprotection through p38 MAPK/SAPK in Drosophila model of tauopathy2023
- Author(s)
  Sakakibara, Y., Yamashiro, R., Chikamatsu, S., Tsubokawa, Y., Nishijima, R., Takei, K., Sekiya, M., Iijima, K.M.
- Organizer
  AD/PD 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] アミロイドβ病理モデルマウスを用いたアルツハイマー病バイオマーカー関連リン酸化タウ181、217、231の脳内局在解析2023
- Author(s)
  廣田湧、榊原泰史、茨木京子、竹井喜美、西島里咲、飯島浩一、関谷倫子
- Organizer
  6NCリトリート（第31回日本医学会総会）
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] アルツハイマー病のプレクリニカル期を検出する血液バイオマーカーリン酸化タウの脳内局在解析2023
- Author(s)
  廣田湧、榊原泰史、竹井喜美、西島里咲、飯島浩一、関谷倫子
- Organizer
  第8回NCGGサマーリサーチセミナー
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] Omics analysis of Alzheimer's disease stratified by the microglial polygenic effect2023
- Author(s)
  Kikuchi, M., Miyashita, A., Hirota, Y., Hara, N., Hasegawa, M., Sakakibara, Y., Sekiya, M., Saito, Y., Murayama, S., Iijima, K.M., Ikeuchi, T.
- Organizer
  Alzheimer’s Association International Conference 2023 (AAIC 2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] Additive effects of delta opioid receptor activation and mu opioid receptor knockout in reducing hopelessness2023
- Author(s)
  Moriya, Y., Kasahara, Y., Shimada, M., Sakakibara, Y., Fujii, H., Nagase, H., Ide, S., Ikeda, K., Hall, F.S., Uhl, G.R., Sora, I.
- Organizer
  8th Congress of Asian College of Neuropsychopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] Reduced density of serotonergic axons without prominent neuron loss or tau pathology in the dorsal raphe nucleus in App knock-in mouse models of amyloid-β pathology2023
- Author(s)
  Sakakibara, Y., Hirota, Y., Ibaraki, K., Takei, K., Nishijima, R., Sekiya, M., Iijima, K.M.
- Organizer
  Alzheimer’s Association International Conference 2023 (AAIC 2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] Alzheimer’s disease biomarker-related phospho-tau 181 signals localize to demyelinated axons of parvalbumin-positive GABAergic interneurons in App knock-in mouse2023
- Author(s)
  Hirota, Y., Sakakibara, Y., Takei, K., Nishijima, R., Iijima, K.M., Sekiya, M.
- Organizer
  Alzheimer’s Association International Conference 2023 (AAIC 2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] μオピオイド受容体欠損マウスにおけるδオピオイド受容体作動薬の相加効果による絶望感軽減の雌雄差2023
- Author(s)
  森屋由紀、笠原好之、嶋田政史、榊原泰史、藤井秀明、長瀬博、井手聡一郎、池田和隆、F.S. Hall、G.R. Uhl、曽良一郎
- Organizer
  第53回日本神経精神薬理学会年会
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] アミロイド病理モデルマウスにおける縫線核セロトニン作動性神経の変性機序の解析2023
- Author(s)
  榊原泰史、廣田湧、茨木京子、竹井喜美、西島里咲、関谷倫子、飯島浩一
- Organizer
  第42回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] Alzheimer’s disease biomarker-related phospho-tau 181 signals localize to demyelinated axons of parvalbumin-positive GABAergic interneurons in App knock-in mouse models of amyloid-β amyloidosis2023
- Author(s)
  Hirota, Y., Sakakibara, Y., Takei, K., Nishijima, R., Sekiya, M., Iijima, K.M.
- Organizer
  IAGG Asia/Oceania Regional Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] δオピオイド受容体作動薬の抗うつ作用におけるμオピオイド受容体の役割.2023
- Author(s)
  森屋由紀、笠原好之、嶋田政史、榊原泰史、藤井秀明、長瀬博、井手聡一郎、池田和隆、F.S. Hall、G.R. Uhl、曽良一郎
- Organizer
  第46回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] ウォルフラム症候群の原因遺伝子WFS1の欠損が加齢性脳病理に及ぼす影響の解析2022
- Author(s)
  榊原泰史、廣田湧、茨木京子、竹井喜美、西島里咲、田部勝也、谷澤幸生、関谷倫子、飯島浩一
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] Reduced density of cholinergic fibers in App knock-in mouse models of Aβ amyloidosis2022
- Author(s)
  Hirota, Y., Sakakibara, Y., Ibaraki, K., Takei, K., Nishijima, R., Iijima, K.M., Sekiya, M.
- Organizer
  Alzheimer’s Association International Conference 2022 (AAIC 2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] A role for the mu opioid receptor in the antidepressant effects of a delta opioid receptor agonist KNT-1272022
- Author(s)
  Moriya, Y., Kasahara, Y., Shimada, M., Sakakibara, Y., Fujii, H., Nagase, H., Ide, S., Ikeda, K., Hall, F.S., Uhl, G.R., Sora, I.
- Organizer
  33rd CINP World Congress of Neuropsychopharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] A Drosophila ortholog of Toll-like receptors modulates c-Jun N-terminal kinase and p38 MAPK signaling and protects against tau-mediated neurodegeneration independent of innate immune response2022
- Author(s)
  Sakakibara, Y., Yamashiro, R., Chikamatsu, S., Tsubokawa, Y., Nishijima, R., Takei, K., Sekiya, M., Iijima, K.M.
- Organizer
  Alzheimer’s Association International Conference 2022 (AAIC 2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] Aβ病理を呈するAppノックインマウスにおけるコリン作動性神経軸索の変性2022
- Author(s)
  廣田湧、榊原泰史、茨木京子、竹井喜美、西島里咲、飯島浩一、関谷倫子
- Organizer
  第41回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] Aβ病理モデルマウスを用いたアルツハイマー病血液バイオマーカーリン酸化タウ181，217，231の脳内局在解析2022
- Author(s)
  廣田湧、榊原泰史、茨木京子、竹井喜美、飯島浩一、関谷倫子
- Organizer
  第45回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] ショウジョウバエToll受容体9は自然免疫応答には影響を与えずJNK シグナル伝達経路を調節し神経保護作用を発揮する2022
- Author(s)
  山城梨沙、榊原泰史、近松幸枝、坪川陽子、西島里咲、竹井喜美、関谷倫子、飯島浩一
- Organizer
  第86回日本生化学会中部支部例会
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] Loss of locus coeruleus-noradrenergic afferents in the App knock-in mouse model of Aβ amyloidosis2021
- Author(s)
  Koichi M. Iijima, Yasufumi Sakakibara, Yu Hirota, Kyoko Ibaraki, Kimi Takei, Yoko Tsubokawa, Takashi Saito, Takaomi C. Saido, Michiko Sekiya
- Organizer
  The 15th International Conference on Alzheimer's & Parkinson's Diseases (AD/PD 2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] Cognitive function and brain pathology in mice with a heterozygous deficiency in ABCC9/SUR2, a gene associated with hippocampal sclerosis of aging2021
- Author(s)
  Yasufumi Sakakibara, Yu Hirota, Sachie Chikamatsu, Kyoko Ibaraki, Kimi Takei, Ming Zhou, Hiroshi Abe, Michiko Sekiya, Koichi M. Iijima
- Organizer
  Alzheimer's Association International Conference (AAIC 2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] Sulfonylurea receptor/Sur deficiency increased vulnerability to neurodegeneration in Drosophila models of Alzheimer’s disease2021
- Author(s)
  Michiko Sekiya, Xiuming Quan, Yasufumi Sakakibara, Sachie Chikamatsu, Koichi M. Iijima
- Organizer
  The 15th International Conference on Alzheimer's & Parkinson's Diseases (AD/PD 2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] 加齢性海馬硬化症関連遺伝子ABCC9のヘテロ欠損マウスにおける認知機能と脳病理の解析2021
- Author(s)
  榊原泰史、廣田湧、近松幸枝、茨木京子、竹井喜美、周明、阿部寛、関谷倫子、飯島浩一
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] AppノックインマウスにおけるADバイオマーカー関連リン酸化タウの脳内局在解析2021
- Author(s)
  廣田湧、榊原泰史、茨木京子、竹井喜美、飯島浩一、関谷倫子
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] Localization of AD biomarker phospho-tau proteins in the brains of App knock-in mouse model of Aβ amyloidosis2021
- Author(s)
  Yu Hirota, Yasufumi Sakakibara, Kyoko Ibaraki, Kimi Takei, Koichi M. Iijima, Michiko Sekiya
- Organizer
  Alzheimer's Association International Conference (AAIC 2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K17655
[Presentation] Appノックインマウスにおける青斑核神経投射とneurovascular couplingの変化の解析2020
- Author(s)
  榊原泰史、茨城京子、竹井喜美、斉藤貴志、西道隆臣、関谷倫子、飯島浩一
- Organizer
  第39回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] Deficiency in a fly ortholog of HS-Aging related gene, sulfonylurea receptor/Sur, increased vulnerability to neurodegeneration in Drosophila models of Alzheimer's disease2020
- Author(s)
  Michiko Sekiya, Xiuming Quan, Yasufumi Sakakibara, Sachie Chikamatsu, Koichi M. Iijima
- Organizer
  Alzheimer's Association International Conference (AAIC 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] 遺伝子ネットワーク解析を用いたアルツハイマー病の発症機序解明と創薬標的の探索2020
- Author(s)
  関谷倫子、Minghui Wang、榊原泰史、近松幸枝、Bin Zhang、飯島浩一
- Organizer
  第93回日本生化学大会
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] Reduced density of noradrenergic fibers without prominent neuron loss or tau pathology in the locus coeruleus in App knock-in mouse models of Aβ amyloidosis2020
- Author(s)
  Koichi M. Iijima, Yasufumi Sakakibara, Yu Hirota, Kyoko Ibaraki, Kimi Takei, Takashi Saito, Takaomi C. Saido, Michiko Sekiya
- Organizer
  Alzheimer's Association International Conference (AAIC 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] アルツハイマー病におけるATP感受性K+チャネル機能の役割2020
- Author(s)
  関谷倫子、権秀明、榊原泰史、近松幸枝、飯島浩一
- Organizer
  第39回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] ネットワーク解析から解き明かすAβ病態2020
- Author(s)
  飯島浩一、Minghui Wang、榊原泰史、Bin Zhang、関谷倫子
- Organizer
  第39回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] Appノックインマウスでは青斑核で神経細胞脱落、またタウ病理は起こらないが、ノルアドレナリン投射線維が減少する2020
- Author(s)
  榊原泰史、茨城京子、竹井喜美、斉藤貴志、西道隆臣、関谷倫子、飯島浩一
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] 新規アルツハイマー病モデルショウジョウバエの作製2019
- Author(s)
  関谷倫子、榊原泰史、近松幸枝、飯島浩一
- Organizer
  第38回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] Amyloid-β plaque formation and reactive gliosis are required for induction of cognitive deficits and synaptic degeneration in App knock-in mouse models of Alzheimer’s disease2019
- Author(s)
  Koichi M. Iijima, Yasufumi Sakakibara, Takashi Saito, Takaomi C. Saido, Michiko Sekiya
- Organizer
  AAIC 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] 加齢性海馬硬化症発症機序の解明2019
- Author(s)
  権秀明、榊原泰史、飯島浩一、関谷倫子
- Organizer
  第11回NAGOYAグローバルリトリート
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] Cognitive deficits and synaptic degeneration in App knock-in mouse models of AD2019
- Author(s)
  飯島浩一、榊原泰史、斉藤貴志、西道隆臣、関谷倫子
- Organizer
  第38回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] アルツハイマー病モデルであるAppノックインマウスにおける認知機能障害はアミロイドβ斑の形成とグリオーシスに起因する2019
- Author(s)
  榊原泰史、関谷倫子、斉藤貴志、西道隆臣、飯島浩一
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] Amyloid-β plaque formation and reactive gliosis are required for induction of cognitive deficits in App knock-in mouse models of Alzheimer’s disease2019
- Author(s)
  Yasufumi Sakakibara, Takashi Saito, Takaomi C. Saido, Michiko, Koichi M. Iijima
- Organizer
  6th Congress of AsCNP
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] A novel Drosophila model of Alzheimer’s disease2019
- Author(s)
  Michiko Sekiya, Yasufumi Sakakibara, Sachie Chikamatsu, Koichi M. Iijima
- Organizer
  AAIC 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] Studying mechanisms underlying hippocampal sclerosis of aging in Drosophila2019
- Author(s)
  Koichi M. Iijima、Xiuming Quan、Yasufumi Sakakibara、Michiko Sekiya
- Organizer
  The 14th International Conference on Alzheimer's & Parkinson's Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] スルフォニル尿素受容体欠損がもたらす老年性神経変性への脆弱性2019
- Author(s)
  権秀明、関谷倫子、榊原泰史、飯島浩一
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] Sur deficiency increases vulnerability to age-related neurodegeneration in Drosophila2019
- Author(s)
  Xiuming Quan, Michiko Sekiya, Yasufumi Sakakibara, Koichi M. Iijima
- Organizer
  Neuroscience 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] 加齢性海馬硬化症モデルショウジョウバエの解析2018
- Author(s)
  飯島浩一、権秀明、榊原泰史、関谷倫子
- Organizer
  第37回日本認知症学会
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] AβアミロイドーシスモデルであるAppノックインマウスにおける情動および認知機能に関する行動解析2018
- Author(s)
  榊原泰史、関谷倫子、斉藤貴志、西道隆臣、飯島浩一
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K15381
[Presentation] 加齢性海馬硬化症発症機序の解明2018
- Author(s)
  権秀明、関谷倫子、榊原泰史、飯島浩一
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-18K15381

1. 関谷倫子 (40367412)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. IDE Soichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

sakakibara yasufumi 榊原 泰史

Sakakibara Yasufumi 榊原 泰史

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老年性認知症の抑うつ症状の原因となるセロトニン神経軸索変性の機序解明Principal Investigator

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Elucidation of mechanisms underlying tau-mediated neurodegeneration by WFS1 deficiencyPrincipal Investigator

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Characterization of a novel genetic modifier of tau-mediated neurodegenerationPrincipal Investigator

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[Journal Article] Drosophila Toll-9 is induced by aging and neurodegeneration to modulate stress signaling and its deficiency exacerbates tau-mediated neurodegeneration2023

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[Journal Article] Alzheimer’s Disease-Related Phospho-Tau181 Signals Are Localized to Demyelinated Axons of Parvalbumin-Positive GABAergic Interneurons in an App Knock-In Mouse Model of Amyloid-β Pathology2023

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[Journal Article] Role for μ-opioid receptor in antidepressant effects of δ-opioid receptor agonist KNT-1272023

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[Journal Article] Distinct brain pathologies associated with Alzheimer’s disease biomarker-related phospho-tau 181 and phospho-tau 217 in <i>App</i> knock-in mouse models of amyloid-β amyloidosis2022

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[Journal Article] Widespread Reduced Density of Noradrenergic Locus Coeruleus Axons in the App Knock-In Mouse Model of Amyloid-β Amyloidosis2021

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[Journal Article] Repeated methamphetamine treatment increases spine density in the nucleus accumbens of serotonin transporter knockout mice2019

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[Journal Article] Amyloid-β plaque formation and reactive gliosis are required for induction of cognitive deficits in App knock-in mouse models of Alzheimer's disease2019

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[Journal Article] Cognitive and emotional alterations in App knock-in mouse models of Aβ amyloidosis2018

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[Presentation] Mechanisms underlying reductions of serotonergic axon projections to the cortex in App knock-in mouse model of Aβ pathology2024

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[Presentation] The delta opioid receptor activation and low mu opioid receptors expression interact to reduce depressive-like behavior2023

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[Presentation] δオピオイド受容体作動薬KNT-127の抗うつ作用におけるμオピオイド受容体の役割2023

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[Presentation] アルツハイマー病バイオマーカーリン酸化タウ181はパルブアルブミン陽性介在ニューロンの有髄軸索に局在する2023

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sakakibara yasufumi 榊原泰史

Sakakibara Yasufumi 榊原泰史