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Goto Hiroki  後藤 裕樹

ORCIDConnect your ORCID iD *help
Researcher Number 20734495
Other IDs
Affiliation (Current) 2025: 熊本大学, 生命資源研究・支援センター, 准教授
Affiliation (based on the past Project Information) *help 2018: 九州大学, 生体防御医学研究所, 助教
2017 – 2018: 熊本大学, エイズ学研究センター, 厚労科研研究員
2015 – 2016: 九州大学, 生体防御医学研究所, 助教
Review Section/Research Field
Principal Investigator
Hematology / Pathological medical chemistry
Except Principal Investigator
Biological Sciences
Keywords
Principal Investigator
ウイルス / 転写因子 / 悪性リンパ腫 / Hippo経路 / シグナル伝達 / Hippo経路
Except Principal Investigator
TAZ / Hippo経路 / 癌 / 細胞・組織 … More / シグナル伝達 / YAP / cell competition / 細胞競合 / YAP1 / Hippo Less
  • Research Projects

    (3 results)
  • Research Products

    (37 results)
  • Co-Researchers

    (15 People)
  •  Role of B-cell transcription factors for the development of primary effusion lymphomaPrincipal Investigator

    • Principal Investigator
      Goto Hiroki
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hematology
    • Research Institution
      Kumamoto University
  •  Elucidation of regulation of osteogenesis and chondrogenesis by Hippo pathwayPrincipal Investigator

    • Principal Investigator
      Goto Hiroki
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kyushu University
  •  Role of Hippo signaling in cell competition

    • Principal Investigator
      Suzuki Akira
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kobe University
      Kyushu University

All 2019 2018 2017 2016 2015 2014

All Journal Article Presentation Book

  • [Book] Targeting the Hippo Signaling Pathway for Cancer Treatment2017

    • Author(s)
      Nakatani K, Maehama T, Nishio M, Goto H, Kato W, Omori H, Miyachi Y, Togashi H, Shimono Y, Suzuki A
    • Publisher
      JOURNAL OF BIOCHEMISTRY
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Book] Hippo vs. Crab: Tissue-specific functions of the mammalian Hippo pathway2017

    • Author(s)
      Nishio M, Maehama T, Goto H, Nakatani K, Kato W, Omori H, Miyachi Y, Togashi H, Shimono Y, Suzuki A
    • Publisher
      GENES TO CELLS
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Book] 機械的刺激によるHippo-YAZ/TAZ経路の活性化,生理作用,腫瘍進展メカニズムと意義2016

    • Author(s)
      後藤裕樹, 西尾美希, 加藤稚子, 前濱朝彦, 鈴木 聡
    • Publisher
      生体の科学
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Book] 生体の科学「YAZ/TAZ経路の活性化、生理作用、腫瘍進展メカニズムと意義」2016

    • Author(s)
      後藤裕樹、西尾美希、加藤稚子、前濱朝彦、鈴木聡
    • Total Pages
      5
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Book] INNOVATIVE MEDICINE : Basic Research and Development (editted by Nakao K)「Pathway: A Candidate New Drug Target for Malignant Tumors」2015

    • Author(s)
      Nishio M, Goto H, Suzuki M, Fujimoto A, Mimori K, Suzuki A
    • Total Pages
      16
    • Publisher
      Springer
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Book] INNOVATIVE MEDICINE2014

    • Author(s)
      Nishio M, Goto H, Suzuki M, Fujimoto A, Mimori K, Suzuki A
    • Publisher
      Springer
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Journal Article] Downregulation of RalGTPase-activating protein promotes invasion of prostatic epithelial cells and progression from intraepithelial neoplasia to cancer during prostate carcinogenesis.2019

    • Author(s)
      Kobayashi T, Uegaki M, Kita Y, Shirakawa R, Teramoto Y, Kamiyama Y, Saito R, Yoshikawa T, Sakamoto H, Goto T, Akamatsu S, Yamasaki T, Inoue T, Suzuki A, Horiuchi H, Ogawa O.
    • Journal Title

      Carcinogenesis

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Journal Article] Effect of histidine on sorafenib-induced vascular damage: Analysis using novel medaka fish model.2018

    • Author(s)
      Shinagawa-Kobayashi Y, Kamimura K, Goto R, Ogawa K, Inoue R, Yokoo T, Sakai N, Nagoya T, Sakamaki A, Abe S, Sugitani S, Yanagi M, Fujisawa K, Nozawa Y, Koyama N, Nishina H, Furutani- Seiki M, Sakaida I, Terai S.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 496 Issue: 2 Pages: 556-561

    • DOI

      10.1016/j.bbrc.2018.01.057

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19701, KAKENHI-PUBLICLY-16H01643, KAKENHI-PUBLICLY-17H05769, KAKENHI-PROJECT-17H04043, KAKENHI-PROJECT-16K15424, KAKENHI-PROJECT-17K09408, KAKENHI-PLANNED-26114005
  • [Journal Article] Effect of a neural relay on liver regeneration in mice: activation of serotonin release from the gastrointestinal tract2018

    • Author(s)
      Inoue Ryosuke、Kamimura Kenya、Nagoya Takuro、Sakai Norihiro、Yokoo Takeshi、Goto Ryo、Ogawa Kohei、Shinagawa-Kobayashi Yoko、Watanabe-Mori Yukari、Sakamaki Akira、Abe Satoshi、Kamimura Hiroteru、Miyamura Norio、Nishina Hiroshi、Terai Shuji
    • Journal Title

      FEBS Open Bio

      Volume: 8 Issue: 3 Pages: 449-460

    • DOI

      10.1002/2211-5463.12382

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H06691, KAKENHI-PROJECT-17K09408, KAKENHI-PROJECT-18K19537, KAKENHI-PLANNED-26114005
  • [Journal Article] Loss of Mob1a/b in mice results in chondrodysplasia due to YAP1/TAZ-TEAD-dependent repression of SOX9.2018

    • Author(s)
      Goto H, Nishio M, To Y, Oishi T, Miyachi Y, Maehama T, Nishina H, Akiyama H, Mak TW, Makii Y, Saito T, Yasoda A, Tsumaki N, Suzuki A.
    • Journal Title

      Development

      Volume: 145 Issue: 6 Pages: 159244-159244

    • DOI

      10.1242/dev.159244

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08626, KAKENHI-PROJECT-17K16188, KAKENHI-PROJECT-15K07020, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-17H01400
  • [Journal Article] Transcriptional regulation of HIV-1 host factor COMMD1 by the Sp family.2018

    • Author(s)
      Kudo E, Taura M, Suico MA, Goto H, Kai H, Okada S.
    • Journal Title

      Int J Mol Med.

      Volume: 41 Pages: 2366-2374

    • DOI

      10.3892/ijmm.2018.3386

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16188
  • [Journal Article] MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion and tumour formation. Oncogene2017

    • Author(s)
      Otsubo K, Goto H, Nishio M, Kawamura K, Yanagi S, Nishie W, Sasaki T, Maehama T, Nishina H, Mimori K, Nakano T, Shimizu H, Mak TW, Nakao K, Nakanishi Y, Suzuki A
    • Journal Title

      Oncogene

      Volume: 印刷中 Issue: 29 Pages: 4201-4211

    • DOI

      10.1038/onc.2017.58

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15495, KAKENHI-PROJECT-15K19026, KAKENHI-PROJECT-15K07020, KAKENHI-PROJECT-16K08626, KAKENHI-PROJECT-17K19608, KAKENHI-PUBLICLY-16H01576, KAKENHI-PUBLICLY-17H05996, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-17H01400, KAKENHI-PROJECT-17H01566, KAKENHI-PROJECT-15H04921, KAKENHI-PROJECT-17H03982, KAKENHI-PROJECT-26640081
  • [Journal Article] Vps34 regulates myofibril proteostasis to prevent hypertrophic cardiomyopathy.2017

    • Author(s)
      Kimura H, Eguchi S, Sasaki J, Kuba K, Nakanishi H, Takasuga S, Yamazaki M, Goto A, Watanabe H, Itoh H, Imai Y, Suzuki A, Mizushima N, Sasaki T
    • Journal Title

      JCI Insight

      Volume: 2 Issue: 1 Pages: 89462-89478

    • DOI

      10.1172/jci.insight.89462

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05978, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-26253083, KAKENHI-PROJECT-15H04693, KAKENHI-PROJECT-26293050, KAKENHI-PROJECT-26460059, KAKENHI-PROJECT-26461458, KAKENHI-PROJECT-15K14947, KAKENHI-PROJECT-15K15304, KAKENHI-PLANNED-25111005, KAKENHI-PROJECT-26440020, KAKENHI-PROJECT-26670132, KAKENHI-PROJECT-15K18857, KAKENHI-PROJECT-17H01400, KAKENHI-PROJECT-26253006, KAKENHI-PROJECT-26640081, KAKENHI-PLANNED-15H05899, KAKENHI-PROJECT-17H03980
  • [Journal Article] Hippo vs. Crab: tissue-specific functions of the mammalian Hippo pathway2017

    • Author(s)
      M. Nishio, T. Maehama, H. Goto, K. Nakatani, W. Kato, H. Omori, Y. Miyachi, H. Togashi, Y. Shimono and A. Suzuki
    • Journal Title

      Genes to Cells

      Volume: 22 Issue: 1 Pages: 6-31

    • DOI

      10.1111/gtc.12461

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26400205, KAKENHI-PROJECT-15K14381, KAKENHI-PROJECT-15K19026, KAKENHI-PROJECT-15K07020, KAKENHI-PROJECT-16K08626, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-17H01400
  • [Journal Article] Targeting the Hippo signalling pathway for cancer treatment2016

    • Author(s)
      K. Nakatani, T. Maehama, M. Nishio, H. Goto, W. Kato, H. Omori, Y. Miyachi, H. Togashi, Y. Shimono and A. Suzuki
    • Journal Title

      J. Biochem.

      Volume: 161 Pages: 237-244

    • DOI

      10.1093/jb/mvw074

    • NAID

      40021162008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26400205, KAKENHI-PROJECT-15K14381, KAKENHI-PROJECT-15K19026, KAKENHI-PROJECT-15K07020
  • [Journal Article] Dysregulated YAP1/TAZ and TGF-beta signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice2016

    • Author(s)
      Nishio M, Sugimachi K, Goto H, Wang J, Morikawa T, Miyachi Y, Takano Y, Hikasa H, Itoh T, Suzuki SO, Kurihara H, Aishima S, Leask A, Sasaki T, Nakano T, Nishina H, Nishikawa Y, Sekido Y, Nakao K, Shin-ya K, Mimori K, Suzuki A
    • Journal Title

      PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCE USA

      Volume: 113(1)

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Journal Article] Dysregulated YAP1/TAZ and TGF signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice2015

    • Author(s)
      Nishio, M., Sugimachi, K., Goto, H., Wang, J., Morikawa, T., Miyachi, Y., Takano, Y., Hikasa, H., Itoh, T., Suzuki, S.O., Kurihara, H., Aishima, S., Leask, A., Sasaki, T., Nakano, T., Nishina, H., Nishikawa, Y., Sekido, Y., Nakao, K., Shin-ya, K., Mimori, K. and Suzuki, A.
    • Journal Title

      PNAS

      Volume: 113 Issue: 1 Pages: 71-80

    • DOI

      10.1073/pnas.1517188113

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07052, KAKENHI-PROJECT-15K14947, KAKENHI-PROJECT-15K15107, KAKENHI-PROJECT-15K19026, KAKENHI-PLANNED-15H05899, KAKENHI-PROJECT-26253006, KAKENHI-PROJECT-15H04921, KAKENHI-PROJECT-26670396, KAKENHI-PROJECT-24390092, KAKENHI-PROJECT-15H02536, KAKENHI-PROJECT-26293012
  • [Journal Article] Hippo経路と腫瘍-Hippo経路変異によるがんモデルマウス-2014

    • Author(s)
      後藤裕樹、西尾美希、杉町圭史、三森功士、鈴木 聡
    • Journal Title

      医学のあゆみ

      Volume: 251(5) Pages: 428-435

    • Data Source
      KAKENHI-PLANNED-26114005
  • [Presentation] 原発性滲出性リンパ腫におけるエピジェネティック制御の破綻2018

    • Author(s)
      岡田 誠治、刈谷 龍昇、後藤 裕樹
    • Organizer
      第22回造血器腫瘍研究会
    • Data Source
      KAKENHI-PROJECT-17K16188
  • [Presentation] Role of Hippo signaling in chondrogenesis.2017

    • Author(s)
      Goto H, Nishio M, Miyachi Y, Nishina H, Suzuki A.
    • Organizer
      EMBO workshop ‘The Hippo pathway across species and disciplines’
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Presentation] Role of MOB1A/1B in salivary gland2017

    • Author(s)
      Miyachi Y, Nishio M, Goto H, Maehama T, Suzuki A.
    • Organizer
      EMBO workshop ‘The Hippo pathway across species and disciplines’.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Presentation] 乳がん幹細胞の潜在転移に伴う独自の幹細胞性制御機構の獲得2017

    • Author(s)
      下野洋平,西村建徳,向山順子,渋谷尚樹,鈴木 聡,後藤典子
    • Organizer
      金沢大学がん進展制御研究所 共同利用・共同研究拠点シンポジウム
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Presentation] オルガノイド培養を用いた転移乳がん幹細胞の幹細胞性制御機構の解析2017

    • Author(s)
      下野洋平,西村建徳,鈴木 聡,後藤典子
    • Organizer
      第1回がん三次元培養研究会
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Presentation] 唾液腺におけるMOB1A/1Bの機能解析2017

    • Author(s)
      宮地洋佑,西尾美希,後藤裕樹,前濱朝彦,鈴木 聡
    • Organizer
      文部科学省 新学術領域研究 学術研究支援基盤形成 先端モデル動物支援プラットフォーム 若手支援技術講習会
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Presentation] 軟骨形成におけるがん抑制遺伝子Mob1の役割2017

    • Author(s)
      後藤裕樹,西尾美希,宮地洋佑,鈴木 聡
    • Organizer
      第76回日本癌学会学術総会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Presentation] MOB1A/1B欠損による肝がん発症機構2016

    • Author(s)
      鈴木 聡, 西尾美希, 杉町圭史, 後藤裕樹, 宮地洋佑, 新家一男,三森功士
    • Organizer
      第20回日本分子標的治療学会シンポジウム~微小環境を標的にした治療
    • Place of Presentation
      別府
    • Year and Date
      2016-05-30
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Presentation] マウス唾液腺におけるMob1a/1bの機能解析2016

    • Author(s)
      宮地洋佑, 西尾美希, 後藤裕樹, 鈴木 聡
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Presentation] Role of Hippo pathway in vivo2016

    • Author(s)
      Miki Nishio, Hiroki Goto, Kohei Otsubo, Hideru Togashi, Yohei Shimono, Tomohiko Maehama, Akira Suzuki
    • Organizer
      第75回日本癌学会学術総会シンポジウムS12 Advances in cancer animal model: from mechanisms to clinical output がん動物モデルの新展開:メカニズムから臨床応用まで
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Presentation] Function of MOB1A/1B in murine liver2015

    • Author(s)
      Miki Nishio, Hiroki Goto, Keishi Sugimachi, Koshi Mimori, Akira Suzuki
    • Organizer
      The Hippo Pathway: Signaling, Development and Disease KEYSTONE SYMPOSIA-on Molecular and Cellular Biology
    • Place of Presentation
      Taos, New Mexico, USA
    • Year and Date
      2015-05-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Presentation] Regulation of chondrogenesis and osteogenesis by Hippo pathway2015

    • Author(s)
      Hiroki Goto, Miki Nishio, Hiroshi Nishina, Akira Suzuki
    • Organizer
      1st International Symposium on Cell Competition.
    • Place of Presentation
      京都
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Presentation] Regulation of chondrogenesis and osteogenesis by Hippo pathway2015

    • Author(s)
      Hiroki Goto, Miki Nishio, Akira Suzuki
    • Organizer
      The 25th Hot Spring Harbor International Symposium, Cutting Edge of Technical Innovations in Structural and Systems Biology 2015
    • Place of Presentation
      福岡
    • Year and Date
      2015-11-13
    • Data Source
      KAKENHI-PROJECT-15K19026
  • [Presentation] Function of MOB1A/1B in murine liver2015

    • Author(s)
      Miki Nishio, Hiroki Goto, Keishi Sugimachi, Koshi Mimori, Akira Suzuki
    • Organizer
      1st International Symposium on Cell Competition.
    • Place of Presentation
      京都
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Presentation] Regulation of chondrogenesis and osteogenesis by Hippo pathway2015

    • Author(s)
      Hiroki Goto, Miki Nishio, Akira Suzuki
    • Organizer
      The 25th Hot Spring Harbor International Symposium
    • Place of Presentation
      福岡
    • Year and Date
      2015-11-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Presentation] マウス肝臓におけるMOB1の機能解析2015

    • Author(s)
      西尾美希、後藤裕樹、大坪孝平、藤 庸子、宮地洋佑、日笠弘基、杉町圭史、三森功士、鈴木 聡
    • Organizer
      Biochemistry and Molecular Biology 2015
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Presentation] Function of MOB1A/1B in murine liver2015

    • Author(s)
      Miki Nishio, Hiroki Goto, Keishi Sugimachi, Koshi Mimori, Akira Suzuki
    • Organizer
      The 18th Retreat Medical Institute of Bioregulation Kyushu University
    • Place of Presentation
      熊本
    • Year and Date
      2015-07-16
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Presentation] Regulation of chondrogenesis and osteogenesis by MOB1A/1B2015

    • Author(s)
      Hiroki Goto, Miki Nishio, Akira Suzuki
    • Organizer
      The 18th Retreat Medical Institute of Bioregulation Kyushu University
    • Place of Presentation
      熊本
    • Year and Date
      2015-07-16
    • Data Source
      KAKENHI-PLANNED-26114005
  • [Presentation] MOB1による生体制御2015

    • Author(s)
      鈴木 聡、西尾美希、後藤裕樹、大坪孝平、藤 庸子、宮地洋佑、日笠弘基、三森功士
    • Organizer
      第24回日本Cell Death学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-07-11
    • Data Source
      KAKENHI-PLANNED-26114005
  • 1.  NISHIO Miki
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 25 results
  • 2.  Suzuki Akira (10311565)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 27 results
  • 3.  仁科 博史 (60212122)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 4.  Maehama Tomohiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 5.  Miyamura Norio
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  Ishihara Erika
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TOGASHI Hideru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 8.  Kamimura Kenya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  Terai Shuji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  MIYACHI Yosuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  中尾 一和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  佐々木 雄彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  清木 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  上村 博輝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  日笠 弘基
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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