ISHIKAWA Naoki 石川直樹

Researcher Number	20748826
Affiliation (based on the past Project Information) *help	2019: 千葉大学, 大学院薬学研究院, 助教 2015 – 2017: 千葉大学, 大学院薬学研究院, 助教 2014 – 2016: 千葉大学, 薬学研究科(研究院), 助教
Review Section/Research Field	Except Principal Investigator Natural medicines / Biomolecular chemistry / Science and Engineering
Keywords	Except Principal Investigator 有機化学 / 生体分子 / 薬学 / 生理活性 / シグナル伝達 / 植物 / 癌 / ヘッジホッグ / ウィント / スクリーニング / 天然物 / 蛋白質

Search and function elucidation of highly active natural products targeting cancer microenvironmental signals
- Principal Investigator
  
  Ishibashi Masami
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Natural medicines
- Research Institution
  Chiba University
Search and functional analysis of natural products targeting intracellular signals that control the development and recurrence of cancer
- Principal Investigator
  
  Ishibashi Masami
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Natural medicines
- Research Institution
  Chiba University
Field study of medicinal natural resources in Bangladesh
- Principal Investigator
  
  Ishibashi Masami
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Chiba University
Search for new natural products ligands having effects on disease and development pathways
- Principal Investigator
  
  Ishibashi Masami
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Chiba University

All 2020 2017 2016 Other

All Journal Article Presentation Patent

[Journal Article] Cadinane sesquiterpenoids isolated from Santalum album using a screening program for Wnt signal inhibitory activity2020
- Author(s)
  Tomoyuki Sato, Midori A. Arai, Yixizhuoma, Yasumasa Hara, Takashi Koyano, Thaworn Kowithayakorn, Masami Ishibashi
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 74 Issue: 2 Pages: 476-481
- DOI
  10.1007/s11418-019-01380-x
- NAID
  40022183696
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03992, KAKENHI-PUBLICLY-19H04640, KAKENHI-PROJECT-20H03394
[Journal Article] Identification of BMI1 Promoter Inhibitors from Beaumontia murtonii and Eugenia operculata2017
- Author(s)
  Kaneta Yui、Arai Midori A.、Ishikawa Naoki、Toume Kazufumi、Koyano Takashi、Kowithayakorn Thaworn、Chiba Tetsuhiro、Iwama Atsushi、Ishibashi Masami
- Journal Title
  
  Journal of Natural Products
  
  Volume: 80 Issue: 6 Pages: 1853-1859
- DOI
  10.1021/acs.jnatprod.7b00138
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07993, KAKENHI-PROJECT-26305001, KAKENHI-PROJECT-17H03992
[Journal Article] Hes1 binding compounds isolated by Target Protein Oriented Natural Products Isolation (TPO-NAPI)2017
- Author(s)
  Arai, M. A.*; Tanaka, M.; Tanouchi, K.; Ishikawa, N.; Ahmed, F.; Sadhu, S. K.; Ishibashi, M.*
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 80 Issue: 2 Pages: 538-543
- DOI
  10.1021/acs.jnatprod.6b01072
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04650, KAKENHI-PROJECT-17H03992
[Journal Article] Elmenols C-H, new angucycline derivatives isolated from a culture of Streptomyces sp. IFM 114902017
- Author(s)
  Yixizhuoma、Ishikawa Naoki、Abdelfattah Mohamed S、Ishibashi Masami
- Journal Title
  
  Journal of Antibiotics
  
  Volume: 70 Issue: 5 Pages: 601-606
- DOI
  10.1038/ja.2016.158
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03992
[Journal Article] Germacranolides from Enhydra fluctuans with TRAIL-resistance abrogating activity2017
- Author(s)
  Ahmed Firoj、Karmakar Utpal K.、Arai Midori A.、Ishikawa Naoki、Samir K. Sadhu、Ishibashi Masami
- Journal Title
  
  Natural Product Communications
  
  Volume: 12 Pages: 1169-1170
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26305001
[Journal Article] Nabscessins A and B, new aminocyclitol derivatives from Nocardia abscessus IFM 10029T2016
- Author(s)
  Shoko Hara, Naoki Ishikawa, Yasumasa Hara, Tatsuo Nehira, Kanae Sakai, Tohru Gonoi, Masami Ishibashi
- Journal Title
  
  Journal of Natural Products
  
  Volume: 80 Issue: 2 Pages: 565-568
- DOI
  10.1021/acs.jnatprod.6b00935
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K05696, KAKENHI-PROJECT-16K14910, KAKENHI-PROJECT-17H03992
[Patent] ナブセシンA、ナブセシンB、及びその製造方法2016
- Inventor(s)
  石橋正己・原昇子・原康雅・石川直樹・酒井香奈江・五ノ井透
- Industrial Property Rights Holder
  千葉大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-120162
- Filing Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-26293022
[Presentation] 標的タンパク質指向型天然物単離による生物活性天然物の探索2017
- Author(s)
  荒井緑，越智富美江，林奈留美，橋本真波，田中光葉，田内加奈，石川直樹，F. Ahmed，S. K. Sadhu，石橋正己
- Organizer
  第59回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-26305001
[Presentation] 標的タンパク質指向型天然物単離による生物活性天然物の探索2017
- Author(s)
  荒井緑，越智富美江，林奈留美，橋本真波，田中光葉，田内加奈，石川直樹，F. Ahmed，S. K. Sadhu，石橋正己
- Organizer
  第59回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-17H03992
[Presentation] 神経幹細胞で働く転写因子Hes1ビーズを用いる迅速的天然物探索
- Author(s)
  石川直樹
- Organizer
  天然有機化合物討論会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PLANNED-23102008

1. ARAI A. Midori (40373261)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. Ishibashi Masami (90212927)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
3. TOUME Kazufumi (80563981)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. 原康雅 (10824625)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 大崎愛弓 (50161360)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 根平達夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 荒井孝義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ISHIKAWA Naoki 石川 直樹

Research Projects

Research Products

Co-Researchers

Search and function elucidation of highly active natural products targeting cancer microenvironmental signals

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search and functional analysis of natural products targeting intracellular signals that control the development and recurrence of cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Field study of medicinal natural resources in Bangladesh

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search for new natural products ligands having effects on disease and development pathways

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Cadinane sesquiterpenoids isolated from Santalum album using a screening program for Wnt signal inhibitory activity2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Identification of BMI1 Promoter Inhibitors from Beaumontia murtonii and Eugenia operculata2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hes1 binding compounds isolated by Target Protein Oriented Natural Products Isolation (TPO-NAPI)2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elmenols C-H, new angucycline derivatives isolated from a culture of Streptomyces sp. IFM 114902017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Germacranolides from Enhydra fluctuans with TRAIL-resistance abrogating activity2017

Author(s)

Journal Title

Data Source

[Journal Article] Nabscessins A and B, new aminocyclitol derivatives from Nocardia abscessus IFM 10029T2016

Author(s)

Journal Title

DOI

Data Source

[Patent] ナブセシンA、ナブセシンB、及びその製造方法2016

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Presentation] 標的タンパク質指向型天然物単離による生物活性天然物の探索2017

Author(s)

Organizer

Data Source

[Presentation] 標的タンパク質指向型天然物単離による生物活性天然物の探索2017

Author(s)

Organizer

Data Source

[Presentation] 神経幹細胞で働く転写因子Hes1ビーズを用いる迅速的天然物探索

Author(s)

Organizer

Place of Presentation

Data Source

ISHIKAWA Naoki 石川直樹