Nakamura Akihiko 中村彰彦

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NAKAMURA Akihiko 中村彰彦

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Researcher Number	20752968
Other IDs
Affiliation (Current)	2025: 静岡大学, グリーン科学技術研究所, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 静岡大学, 農学部, 准教授 2018: 分子科学研究所, 生命・錯体分子科学研究領域, 助教 2015 – 2017: 大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 助教
Review Section/Research Field	Principal Investigator Biophysics / Basic Section 43040:Biophysics-related / Basic Section 41050:Environmental agriculture-related / Complex systems Except Principal Investigator Medium-sized Section 40:Forestry and forest products science, applied aquatic science, and related fields / Basic Section 40020:Wood science-related
Keywords	Principal Investigator バイオマス / 1分子計測 / キチナーゼ / 一分子観察 / 糖質加水分解酵素 / キチン / セルロース / セルラーゼ / 酸化還元酵素 / 結晶性基質 … More / プロセッシビティ / PET加水分解酵素 / 構造機能相関 / 海洋微生物 / 吸着 / 海洋性バクテリア / 動力学解析 / １分子計測 / ビブリオ / 糖質吸着ドメイン / ビブリオ菌 / キチン加水分解酵素 / 反応速度論解析 / 加水分解酵素 / 結晶構造解析 / 一分子解析 / 分子モーター / プロセッシブ運動 / X線構造解析 / モータータンパク / 糖鎖修飾 / キネティクス … More Except Principal Investigator 分子育種 / 低分子リグニン / アジピン酸誘導体 / 高活性リグニン分解菌 / バイオリファイナリー / 3-ヒドロキシアジピン酸 / リグニン / 白色腐朽菌 / リグノセルロース / バイオマス分解 / 一分子観察 / 担子菌 / 放線菌 / キシラン分解 / バイオマス / キシラナーゼ / キシラン / ヘミセルラーゼ / ヘミセルロース Less

天然結晶分解酵素を模倣した結晶性プラスチック分解酵素システムの開発Principal Investigator
- Principal Investigator
  
  中村彰彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Shizuoka University
高活性リグニン分解菌を用いた新規リグニンリファイナリー技術の構築
- Principal Investigator
  
  平井浩文
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 40:Forestry and forest products science, applied aquatic science, and related fields
- Research Institution
  Shizuoka University
Elucidation of "biomass decompositionmechanism" learning from nature
- Principal Investigator
  
  Kaneko Satoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 40020:Wood science-related
- Research Institution
  University of the Ryukyus
Single molecule analysis of carbohydrate degrading enzyme with double binding domains form marine bacteriumPrincipal Investigator
- Principal Investigator
  
  Nakamura Akihiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 41050:Environmental agriculture-related
- Research Institution
  Shizuoka University
Analysis of degradation mechanism of crystalline carbohydrates by high speed and precision single molecule observationPrincipal Investigator
- Principal Investigator
  
  Nakamura Akihiko
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Institute for Molecular Science
  Okazaki Research Facilities, National Institutes of Natural Sciences
高時空間分解能一分子観察と理論解析を組み合わせた分子モーター運動解析法の開発Principal Investigator
- Principal Investigator
  
  中村彰彦
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Institute for Molecular Science
  Okazaki Research Facilities, National Institutes of Natural Sciences
Analysis of structural element of cellulases for processive movementPrincipal Investigator
- Principal Investigator
  
  NAKAMURA Akihiko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biophysics
- Research Institution
  Okazaki Research Facilities, National Institutes of Natural Sciences

All 2021 2020 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Label-free monitoring of crystalline chitin hydrolysis by chitinase based on Raman spectroscopy2021
- Author(s)
  Ando Jun、Kawagoe Hiroyuki、Nakamura Akihiko、Iino Ryota、Fujita Katsumasa
- Journal Title
  
  The Analyst
  
  Volume: 146 Issue: 12 Pages: 4087-4094
- DOI
  10.1039/d1an00581b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03094
[Journal Article] Role of Tryptophan 38 in Loading Substrate Chain into the Active-site Tunnel of Cellobiohydrolase I from <i>Trichoderma reesei</i>2021
- Author(s)
  Nakamura, A., Kanazawa, T. Furuta, T., Sakurai, M., Saloheimo, M., Samejima, M., Koivula, A., Igarashi, K.
- Journal Title
  
  Journal of Applied Glycoscience
  
  Volume: 68 Issue: 1 Pages: 19-29
- DOI
  10.5458/jag.jag.JAG-2020_0014
- NAID
  130007996787
- ISSN
  1344-7882, 1880-7291
- Year and Date
  2021-03-11
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05494, KAKENHI-PROJECT-19H03094
[Journal Article] Positive Charge Introduction on the Surface of Thermostabilized PET Hydrolase Facilitates PET Binding and Degradation2021
- Author(s)
  Nakamura Akihiko、Kobayashi Naoya、Koga Nobuyasu、Iino Ryota
- Journal Title
  
  ACS Catalysis
  
  Volume: 11 Issue: 14 Pages: 8550-8564
- DOI
  10.1021/acscatal.1c01204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03094, KAKENHI-PLANNED-18H05420, KAKENHI-PLANNED-18H05424
[Journal Article] Domain architecture divergence leads to functional divergence in binding and catalytic domains of bacterial and fungal cellobiohydrolases2020
- Author(s)
  Nakamura A, Ishiwata D, Visootsat A, Uchiyama T, Mizutani K, Kaneko S, Murata T, Igarashi K, Iino R
- Journal Title
  
  J Biol Chem
  
  Volume: 295 Issue: 43 Pages: 14606-14617
- DOI
  10.1074/jbc.ra120.014792
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05424, KAKENHI-PLANNED-18H05425, KAKENHI-PLANNED-18H05494, KAKENHI-PROJECT-19H03094
[Journal Article] Combined approach to engineer a highly active mutant of processive chitinase hydrolyzing crystalline chitin2020
- Author(s)
  Visootsat A, Nakamura A, Wang T-W, Iino R
- Journal Title
  
  ACS Omega
  
  Volume: 5 Issue: 41 Pages: 26807-26816
- DOI
  10.1021/acsomega.0c03911
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05424, KAKENHI-PROJECT-19H03094
[Journal Article] Visualization of functional structure and kinetic dynamics of cellulases2018
- Author(s)
  Akihiko Nakamura, Ryota Iino
- Journal Title
  
  Glycobiophysics
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05899
[Journal Article] Single-molecule imaging and manipulation of biomolecular machines and systems2018
- Author(s)
  Iino Ryota、Iida Tatsuya、Nakamura Akihiko、Saita Ei-ichiro、You Huijuan、Sako Yasushi
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1862 Issue: 2 Pages: 241-252
- DOI
  10.1016/j.bbagen.2017.08.008
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0087, KAKENHI-PROJECT-16K14716, KAKENHI-PROJECT-17K18429, KAKENHI-PUBLICLY-16H00788, KAKENHI-PUBLICLY-16H00789, KAKENHI-PUBLICLY-17H05899, KAKENHI-PUBLICLY-17H06021, KAKENHI-PROJECT-15H02394
[Journal Article] Visualization of functional structure and kinetic dynamics of cellulases2018
- Author(s)
  Akihiko Nakamura, Ryota Iino
- Journal Title
  
  Glycobiophysics
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K18429
[Journal Article] Rate constants, processivity, and productive binding ratio of chitinase A revealed by single- molecule analysis2018
- Author(s)
  Akihiko Nakamura, Tomoyuki Tasaki, Yasuko Okuni, Chihong Song, Kazuyoshi Murata, Toshiya Kozai, Mayu Hara, Hayuki Sugimoto, Kazushi Suzuki, Takeshi Watanabe, Takayuki Uchihashi, Hiroyuki Noji and Ryota Iino
- Journal Title
  
  Phys. Chem. Chem. Phys.
  
  Volume: 20 Issue: 5 Pages: 3010-3018
- DOI
  10.1039/c7cp04606e
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K18429, KAKENHI-PUBLICLY-16H00758, KAKENHI-PUBLICLY-16H00830, KAKENHI-PUBLICLY-16H00858, KAKENHI-PUBLICLY-17H05899, KAKENHI-PROJECT-15H03540, KAKENHI-PROJECT-15K07355, KAKENHI-PROJECT-26000011, KAKENHI-PROJECT-17K19519, KAKENHI-PROJECT-16H06280
[Journal Article] Processive chitinase is Brownian monorail operated by fast catalysis after peeling rail from crystalline chitin2018
- Author(s)
  Nakamura Akihiko、Okazaki Kei-ichi、Furuta Tadaomi、Sakurai Minoru、Iino Ryota
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 3814-3814
- DOI
  10.1038/s41467-018-06362-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05899, KAKENHI-PLANNED-18H05424, KAKENHI-PROJECT-17K18429
[Journal Article] Single-molecule imaging analysis of binding, processive movement, and dissociation of cellobiohydrolase Trichoderma reesei Cel6A and its domains on crystalline cellulose2016
- Author(s)
  Nakamura A, Tasaki T, Ishiwata D, Yamamoto M, Okuni Y, Visootsat A, Maximilien M, Noji H, Uchiyama T, Samejima M, Igarashi K, Iino R
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 291 Issue: 43 Pages: 22404-22413
- DOI
  10.1074/jbc.m116.752048
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H00789, KAKENHI-PLANNED-24114008, KAKENHI-PROJECT-15H06898, KAKENHI-PROJECT-15K07383, KAKENHI-PROJECT-26000011
[Presentation] バクテリア及びカビ由来 GH6 セロビオヒドロラーゼのドメイン機能の違い2020
- Author(s)
  中村彰彦,石渡大貴,Akasit Visootsat,内山拓,水谷健二,金子哲,村田武士,五十嵐圭日子, 飯野亮太
- Organizer
  日本応用糖質科学会 2020 年度大会
- Data Source
  KAKENHI-PROJECT-19H03094
[Presentation] Resolving 1 nm steps of a Brownian-ratchet chitinase with gold nano particle2018
- Author(s)
  Akihiko Nakamura, Ryota Iino
- Organizer
  日本化学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05899
[Presentation] Direct observation of 1 nm steps of a “burnt‐bridge” Brownian ratchet SmChiA on crystalline chitin with gold nanoprobe2018
- Author(s)
  Akihiko Nakamura
- Organizer
  The 79th Okazaki Conference Synthetic, Biological, and Hybrid Molecular Engines
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05899
[Presentation] キチン加水分解酵素は ATP を使わずに運動するブラウニアンラチェットである2018
- Author(s)
  中村彰彦
- Organizer
  分子モーター討論会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05899
[Presentation] Resolving 1 nm steps of a Brownian-ratchet chitinase with gold nano particle2018
- Author(s)
  Akihiko Nakamura
- Organizer
  International Symposium on Molecular Science - Physical Chemistry / Theoretical Chemistry, Chemoinformatics, Computational Chemistry - Cosponsored by Japan Society for Molecular Science
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05899
[Presentation] rocessive chitinase is Brownian ratchet moving unidirectionally by fast catalysis2018
- Author(s)
  Akihiko Nakamura
- Organizer
  Sendai Molecular Motor Meeting 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18429
[Presentation] Processive chitinase is Brownian ratchet moving unidirectionally by fast catalysis2018
- Author(s)
  Akihiko Nakamura
- Organizer
  Sendai Molecular Motor Meeting 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05899
[Presentation] キチン加水分解酵素は速い加水分解でブラウン運動を制御する2018
- Author(s)
  中村彰彦
- Organizer
  多糖の未来フォーラム
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05899
[Presentation] Resolving 1 nm steps of a Brownian-ratchet chitinase with gold nano particle2018
- Author(s)
  Akihiko Nakamura
- Organizer
  International Symposium on Molecular Science - Physical Chemistry / Theoretical Chemistry, Chemoinformatics, Computational Chemistry - Cosponsored by Japan Society for Molecular Science
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18429
[Presentation] キチン加水分解酵素は ATP を使わずに運動するブラウニアンラチェットである2018
- Author(s)
  中村彰彦
- Organizer
  分子モーター討論会
- Invited
- Data Source
  KAKENHI-PROJECT-17K18429
[Presentation] キチン加水分解酵素は速い加水分解でブラウン運動を制御する2018
- Author(s)
  中村彰彦
- Organizer
  多糖の未来フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-17K18429
[Presentation] Direct observation of 1 nm steps of a “burnt‐bridge” Brownian ratchet SmChiA on crystalline chitin with gold nanoprobe2018
- Author(s)
  Akihiko Nakamura
- Organizer
  The 79th Okazaki Conference Synthetic, Biological, and Hybrid Molecular Engines
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18429
[Presentation] 1 分子解析によりセルラーゼ/キチナーゼの何が見えるのか2017
- Author(s)
  中村彰彦
- Organizer
  セルラーゼ研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K18429
[Presentation] Direct Observation of 1 nm Steps of Chitinase A Molecules with Gold Nano Probes2017
- Author(s)
  Akihiko Nakamura, Ryota Iino
- Organizer
  Gordon Research Conference Cellulases & Other Carbohydrate-Active Enzymes
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05899
[Presentation] 1 分子解析によりセルラーゼ/キチナーゼの何が見えるのか2017
- Author(s)
  中村彰彦
- Organizer
  セルラーゼ研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05899
[Presentation] Direct Observation of 1 nm Steps of Chitinase A Molecules with Gold Nano Probes2017
- Author(s)
  Akihiko Nakamura, Ryota Iino
- Organizer
  Gordon Research Conference Cellulases & Other Carbohydrate-Active Enzymes
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K18429
[Presentation] 霊菌Serratia marcescens由来キチナーゼSmChiAの運動律速段階の解明2017
- Author(s)
  中村彰彦、飯野亮太
- Organizer
  日本応用糖質学会
- Data Source
  KAKENHI-PROJECT-17K18429
[Presentation] One nanometer steps and the rate-limiting step of Serratia marcescens chitinase A resolved by gold nanoprobe2017
- Author(s)
  Akihiko Nakamura, Ryota Iino
- Organizer
  日本生物物理学会
- Data Source
  KAKENHI-PROJECT-17K18429
[Presentation] 霊菌Serratia marcescens由来キチナーゼSmChiAの運動律速段階の解明2017
- Author(s)
  中村彰彦、飯野亮太
- Organizer
  日本応用糖質学会
- Data Source
  KAKENHI-PUBLICLY-17H05899
[Presentation] One nanometer steps and the rate-limiting step of Serratia marcescens chitinase A resolved by gold nanoprobe2017
- Author(s)
  Akihiko Nakamura, Ryota Iino
- Organizer
  日本生物物理学会
- Data Source
  KAKENHI-PUBLICLY-17H05899
[Presentation] Single-molecule fluorescence analysis of binding, dissociation, and processive movement of bacterial and fungal cellobiohydrolases2016
- Author(s)
  Daiki Ishiwata, Akihiko Nakamura, Tomoyuki Tasaki, Akasit Visootsat, Maximilien Morice and Ryota Iino
- Organizer
  第54回日本生物物理学会
- Place of Presentation
  茨城県、つくば市、つくば国際会議場
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-15H06898
[Presentation] Single-molecule fluorescence imaging analysis of processive movement of a bacterial Cellulase Cellulomonas fimi Cel6B2015
- Author(s)
  Daiki Ishiwata, Akihiko Nakamura, Tomoyuki Tasaki, Ryota Iino
- Organizer
  第53回　日本生物物理学会年会
- Place of Presentation
  金沢大学 (石川県金沢市)
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-15H06898
[Presentation] Single-molecule fluorescence imaging analysis of processive movement of fungal cellulases Trichoderma reesei Cel6A and Cel7A2015
- Author(s)
  Tomoyuki Tasaki, Akihiko Nakamura, Daiki Ishiwata, Hiroyuki Noji, Ryota Iino
- Organizer
  第53回　日本生物物理学会年会
- Place of Presentation
  金沢大学 (石川県金沢市)
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-15H06898

1. Kaneko Satoshi (90343821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 五十嵐圭日子 (80345181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 平井浩文 (70322138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Okazaki Kei-ichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Iino Ryota

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. 佐甲靖志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakamura Akihiko 中村 彰彦

NAKAMURA Akihiko 中村 彰彦

Research Projects

Research Products

Co-Researchers

天然結晶分解酵素を模倣した結晶性プラスチック分解酵素システムの開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

高活性リグニン分解菌を用いた新規リグニンリファイナリー技術の構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of "biomass decompositionmechanism" learning from nature

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Single molecule analysis of carbohydrate degrading enzyme with double binding domains form marine bacteriumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of degradation mechanism of crystalline carbohydrates by high speed and precision single molecule observationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

高時空間分解能一分子観察と理論解析を組み合わせた分子モーター運動解析法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of structural element of cellulases for processive movementPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Label-free monitoring of crystalline chitin hydrolysis by chitinase based on Raman spectroscopy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of Tryptophan 38 in Loading Substrate Chain into the Active-site Tunnel of Cellobiohydrolase I from <i>Trichoderma reesei</i>2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Positive Charge Introduction on the Surface of Thermostabilized PET Hydrolase Facilitates PET Binding and Degradation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Domain architecture divergence leads to functional divergence in binding and catalytic domains of bacterial and fungal cellobiohydrolases2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Combined approach to engineer a highly active mutant of processive chitinase hydrolyzing crystalline chitin2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Visualization of functional structure and kinetic dynamics of cellulases2018

Author(s)

Journal Title

Data Source

Nakamura Akihiko 中村彰彦

NAKAMURA Akihiko 中村彰彦