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0 0  坊野 恵子

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… Alternative Names

Bono Keiko  坊野 恵子

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Researcher Number 20753320
Other IDs
Affiliation (Current) 2025: 東京慈恵会医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2018 – 2023: 東京慈恵会医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 52020:Neurology-related
Keywords
Principal Investigator
オートファジー / VPS35 / iPS細胞 / パーキンソン病 / Rab9 / PARK17 / PAKR17 / レトロマー / エンドソーム
  • Research Projects

    (2 results)
  • Research Products

    (5 results)
  •  家族性パーキンソン病PARK17由来iPS細胞を用いたオートファジー障害の解析Principal Investigator

    • Principal Investigator
      坊野 恵子
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Jikei University School of Medicine
  •  Cell biological analysis of VPS35 mutation using iPSCsPrincipal Investigator

    • Principal Investigator
      Bono Keiko
    • Project Period (FY)
      2018 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Jikei University School of Medicine

All 2024 2023 2020 2019

All Journal Article Presentation

  • [Journal Article] The impact of VPS35 D620N mutation on alternative autophagy and its reversal by estrogen in Parkinson's disease2024

    • Author(s)
      Tomotaka Shiraishi, Keiko Bono, Hiromi Hiraki, Yoko Manome, Hisayoshi Oka, Yasuyuki Iguchi, Hirotaka James Okano
    • Journal Title

      Cellular and Molecular Life Sciences

      Volume: 81 Issue: 1 Pages: 103-103

    • DOI

      10.1007/s00018-024-05123-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K15719, KAKENHI-PROJECT-21K07302, KAKENHI-PROJECT-18K15468, KAKENHI-PROJECT-22KJ2783
  • [Journal Article] Specific vulnerability of iPSC-derived motor neurons with TDP-43 gene mutation to oxidative stress2023

    • Author(s)
      Asako Onda-Ohto, Minami Hasegawa-Ogawa, Hiromasa Matsuno, Tomotaka Shiraishi, Keiko Bono, Hiromi Hiraki, Yumi Kanegae, Yasuyuki Iguchi, Hirotaka James Okano
    • Journal Title

      Molecular Brain

      Volume: 16 Issue: 1 Pages: 62-62

    • DOI

      10.1186/s13041-023-01050-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K15719, KAKENHI-PROJECT-22K20696, KAKENHI-PROJECT-23K06812, KAKENHI-PROJECT-18K15468
  • [Journal Article] Endosomal dysfunction in iPSC-derived neural cells from Parkinson's disease patients with VPS35 D620N2020

    • Author(s)
      Keiko Bono, Chikako Hara-Miyauchi, Shunsuke Sumi, Hisayoshi Oka, Yasuyuki Iguchi, Hirotaka James Okano
    • Journal Title

      Molecular Brain

      Volume: 13 Issue: 1

    • DOI

      10.1186/s13041-020-00675-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15468
  • [Presentation] 疾患iPS細胞を用いたVPS35遺伝子変異パーキンソン病の病態解析2019

    • Author(s)
      坊野恵子
    • Organizer
      日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-18K15468
  • [Presentation] Cell biological analysis of VPS35 mutation using iPSCs2019

    • Author(s)
      Keiko Bono, Chikako Hara, Syunsuke Sumi, Yasuyuki Iguchi, Hirotaka James Okano
    • Organizer
      日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K15468

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