Matsuhisa Fumikazu 松久葉一

… Alternative Names

MATSUHISA Fumikazu 松久葉一

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Researcher Number	20754253
Other IDs
Affiliation (Current)	2025: 佐賀大学, 総合分析実験センター, 助教
Affiliation (based on the past Project Information) *help	2017 – 2024: 佐賀大学, 総合分析実験センター, 助教 2015: 佐賀大学, 総合分析実験センター, 助教
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Laboratory animal science
Keywords	Principal Investigator 細胞内シグナル伝達 / ADP受容体 / グルココルチコイド / 巨核球 / 血小板 Except Principal Investigator ウサギ / 動脈硬化 / ウサギモデル / ANGPTLs / 脂質代謝異常 … More / 遺伝子欠損ウサギ / アポリポタンパクA-V / ゲノム編集 / アポリポ蛋白A-V / ノックアウト / CRISPR-Cas9 / リポ蛋白代謝 / レムナントリポタンパク / 食後高脂血症 / 脂質異常症 / 中性脂肪 / リポタンパク / アポA-V / 実験動物学 / 系統保存 / 生殖工学 / 疾患モデル / バイオリソース / 凍結保存 Less

高感受性血小板産生の展望：巨核球系細胞に及ぼすストレスホルモンの作用Principal Investigator
- Principal Investigator
  
  松久葉一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Saga University
Effects of ANGPTLs on dyslipidemia and atherosclerosis: analysis using gene-modified rabbits.
- Principal Investigator
  
  西島和俊
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Okazaki Research Facilities, National Institutes of Natural Sciences
Functions of apo A-V in atherosclerosis: a study of knockout rabbit model
- Principal Investigator
  
  Niimi Manabu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  University of Yamanashi
Improvement of reproductive technology in rabbit
- Principal Investigator
  
  Kitajima Shuji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Saga University
Establishment of freezing method of rabbit embryos for cryopreservation of laboratory rabbits as human disease models
- Principal Investigator
  
  KITAJIMA Shuji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Saga University

All 2023 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Macrophage‐derived MMP‐9 enhances the progression of atherosclerotic lesions and vascular calcification in transgenic rabbits2020
- Author(s)
  Chen Yajie、Waqar Ahmed Bilal、Nishijima Kazutoshi、Ning Bo、Kitajima Shuji、Matsuhisa Fumikazu、Chen Lu、Liu Enqi、Koike Tomonari、Yu Ying、Zhang Jifeng、Chen Yuqing Eugene、Sun Huijun、Liang Jingyan、Fan Jianglin
- Journal Title
  
  Journal of Cellular and Molecular Medicine
  
  Volume: 24 Issue: 7 Pages: 4261-4274
- DOI
  10.1111/jcmm.15087
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07138
[Journal Article] Apolipoprotein CIII Deficiency Protects Against Atherosclerosis in Knockout Rabbits2020
- Author(s)
  Yan Haizhao、Niimi Manabu、Matsuhisa Fumikazu、Zhou Huanjin、Kitajima Shuji、Chen Yajie、Wang Chuan、Yang Xiawen、Yao Jian、Yang Dongshan、Zhang Jifeng、Murakami Masami、Nakajima Katsuyuki、Wang Yao、Liu Enqi、Liang Jingyan、Chen Y. Eugene、Fan Jianglin
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 40 Issue: 9 Pages: 2095-2107
- DOI
  10.1161/atvbaha.120.314368
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08858, KAKENHI-PROJECT-20KK0190
[Journal Article] Macrophage-derived matrix metalloproteinase-1 enhances aortic aneurysm formation in transgenic rabbits.2019
- Author(s)
  Niimi, M., Nishijima, K., Kitajima, S., Matsuhisa, F., Satoh, K., Yamazaki, H., Zhang, J., Chen, Y.E., Fan, J
- Journal Title
  
  J. Biomed. Res.
  
  Volume: 33 Pages: 271-279
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07138
[Journal Article] Sex hormones affect endothelial lipase-mediated lipid metabolism and atherosclerosis2019
- Author(s)
  Wang Chuan、Niimi Manabu、Kitajima Shuji、Matsuhisa Fumikazu、Yan Haizhao、Dong Sijun、Liang Jingyan、Fan Jianglin
- Journal Title
  
  Lipids in Health and Disease
  
  Volume: 18 Issue: 1 Pages: 226-226
- DOI
  10.1186/s12944-019-1175-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07138, KAKENHI-PROJECT-17K08783
[Journal Article] Growing oocyte specific transcription-dependent de novo DNA methylation at the imprinted Zrsr1-DMR2018
- Author(s)
  Joh, K., Matsuhisa, F., Kitajima, S., Nishioka, K., Higashimoto, K., Yatsuki, H., Kono, T., Koseki, H., Soejima, H.
- Journal Title
  
  Epigenetics & Chromatin
  
  Volume: 11 Issue: 1 Pages: 28-28
- DOI
  10.1186/s13072-018-0200-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07138, KAKENHI-PROJECT-17K08687, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-16K09970, KAKENHI-PROJECT-18H00338
[Journal Article] ウサギ精子凍結保存液における卵黄代替物としての大豆由来機能性改質レシチンに関する検討2018
- Author(s)
  松尾　完，松久葉一，秋吉俊明，西島和俊，森本正敏，北嶋修司
- Journal Title
  
  九州実験動物雑誌
  
  Volume: 34 Pages: 15-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07138
[Journal Article] Increased hepatic expression of endothelial lipase inhibits cholesterol diet induced hypercholesterolemia and atherosclerosis in transgenic rabbits2017
- Author(s)
  Wang, C., Nishijima, K., Kitajima, S., Niimi, M., Yan, H., Chen, Y., Ning, B., Matsuhisa, F., Liu, E., Zhang, J., Chen, Y. E., Fan. J.
- Journal Title
  
  Arterioscler. Thromb. Vasc. Biol.
  
  Volume: 37 Issue: 7 Pages: 1282-1289
- DOI
  10.1161/atvbaha.117.309139
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07138, KAKENHI-PROJECT-17K08783, KAKENHI-PROJECT-15H04718
[Presentation] アポE欠損カイロミクロンレムナントはウサギの動脈硬化を促進させる2023
- Author(s)
  新見学、松久葉一、唐向明、陳露、Chen Yajie、Yan Haizhao、北嶋修司、範江林
- Organizer
  第6回日本ウサギバイオサイエンス研究会学術集会
- Data Source
  KAKENHI-PROJECT-20K08858
[Presentation] 中性脂肪代謝異常の新規疾患モデル：アポA-V欠損ウサギの樹立2023
- Author(s)
  新見学、松久葉一、北嶋修司、範江林
- Organizer
  第70回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-20K08858
[Presentation] Apolipoprotein CIII deficiency inhibits cholesterol diet-induced hyperlipidemia and atherosclerosis in knockout rabbits2021
- Author(s)
  Haizhao Yan, Manabu Niimi, Fumikazu Matsuhisa, Xiawen Yang, Huanjin Zhou, Shuji Kitajima, Yajie Chen, Chuan Wang, Jian Yao, Dongshan Yang, Jifeng Zhang, Masami Murakami, Katsuyuki Nakajima, Yao Wang, Enqi Liu, Jingyan Liang, Liangxue Lai, Y. Eugene Chen, Jianglin Fan
- Organizer
  The 19th International Symposium on Atherosclerosis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08858
[Presentation] カイロミクロンレムナントはアポE欠損ウサギの動脈硬化進展を促進させる2021
- Author(s)
  新見学、松久葉一、北嶋修司、範江林
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-20K08858
[Presentation] カイロミクロンレムナントは動脈硬化進展を促進させる：アポE欠損ウサギを用いた研究2021
- Author(s)
  新見学、松久葉一、周煥錦、Chen Yajie、Yan Haizhao、北嶋修司、範江林
- Organizer
  第53回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-20K08858
[Presentation] Deletion of the apoCIII gene in knockout rabbits attenuates cholesterol diet-induced hyperlipidemia and protects against atherosclerosis2020
- Author(s)
  Yan H, Niimi M, Zhou H, Matsuhisa F, Kitajima S, Yang X, Chen YJ, Murakami M, Nakajima K, Liang J, Jifeng Zhang J, Chen YE, Yao J, Fan J.
- Organizer
  88th European Atherosclerosis Society (EAS) Congress 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08858
[Presentation] 若齢ウサギから過排卵処置により採取した卵子の受精能力について2019
- Author(s)
  秋吉俊明、吉岡翔太、松久葉一、向平崚太郎、森本正敏、塩見雅志、北嶋修司
- Organizer
  第36回九州実験動物研究会
- Data Source
  KAKENHI-PROJECT-17K07138
[Presentation] 内皮リパーゼは脂質低下を介して抗動脈硬化作用を発揮する－遺伝子改変ウサギを用いた検討－2019
- Author(s)
  新見学、Yan Haizhao、Chen Yajie、Zhou Huanjin、王川、松久葉一、西島和俊、北嶋修司、範江林
- Organizer
  第51回日本動脈硬化学会
- Data Source
  KAKENHI-PROJECT-17K07138
[Presentation] 超急速ガラス化法によるWHHLウサギ胚の凍結成績について2019
- Author(s)
  向平崚太郎、松久葉一、高井直史、前田達弘、水田あい、吉岡翔太、森本正敏、北嶋修司
- Organizer
  第36回九州実験動物研究会
- Data Source
  KAKENHI-PROJECT-17K07138
[Presentation] ウサギ体外受精における精子前培養法の検討2019
- Author(s)
  吉岡翔太、秋吉俊明、松久葉一、向平崚太郎、森本正敏、北嶋修司
- Organizer
  第36回九州実験動物研究会
- Data Source
  KAKENHI-PROJECT-17K07138
[Presentation] Transcription-dependent de novo DNA methylation at the imprinted Zrsr1-DMR occurs in the growing oocyte, but not in early embryonic cells2018
- Author(s)
  Hidenobu Soejima, Fumikazu Matsuhisa,Shuji Kitajima, Kenichi Nishioka, Ken Higashimoto, Hitomi Yatsuki, Tomohiro Kono, Haruhiko Koseki, Keiichiro Joh
- Organizer
  European Human Genetics Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07138
[Presentation] Characterization of apolipoprotein C-III knockout rabbits2018
- Author(s)
  Haizhao Yan, Manabu Niimi, Fumikazu Matsuhisa, Shuji Kitajima, Y. Eugene Chen, Jianglin Fan
- Organizer
  第5回日本ウサギバイオサイエンス研究会
- Data Source
  KAKENHI-PROJECT-17K07138
[Presentation] WHHLMIウサギの凍結胚による系統保存に関する検討2018
- Author(s)
  松久葉一、秋吉俊明、塩見雅志、向平峻太郎、吉岡翔太、森本正敏、北嶋修司
- Organizer
  第5回日本ウサギバイオサイエンス研究会
- Data Source
  KAKENHI-PROJECT-17K07138
[Presentation] 若齢ウサギにおける過排卵処置および卵子回収の試み（その２）2018
- Author(s)
  秋吉俊明、松久葉一、向平崚太郎、吉岡翔太、森本正敏、塩見雅志、北嶋修司
- Organizer
  第5回日本ウサギバイオサイエンス研究会
- Data Source
  KAKENHI-PROJECT-17K07138
[Presentation] パルス電界印加によるウサギ精子の先体反応の誘導2018
- Author(s)
  白石将平、猪原　哲、松久葉一、北嶋修司
- Organizer
  平成30年電気学会全国大会
- Data Source
  KAKENHI-PROJECT-17K07138
[Presentation] Comparison of cryoprotectants for ultra-rapid vitrification (Cryotop method) in rabbit embryos2017
- Author(s)
  Fumikazu Matsuhisa, Toshiaki Akiyoshi, Kan Matsuo, Masatohi Morimoto, Manabu Niimi, Jianglin Fan, Shuji Kitajima
- Organizer
  The 7th International Meeting on Rabbit Biotechnology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07138
[Presentation] Macrophage-derived matrix metalloprotease-1 accelerates aortic aneurysm formation in transgenic rabbits2017
- Author(s)
  Manabu Niimi, Kazutoshi Nishijima, Shuji Kitajima, Fumikazu Matsuhisa, Kaneo Satoh, Jianglin Fan
- Organizer
  第49回日本動脈硬化学会
- Data Source
  KAKENHI-PROJECT-17K07138
[Presentation] ウサギ精子の凍結保存における大豆由来分別レシチンの有用性について2017
- Author(s)
  松尾　完、松久葉一、秋吉俊明、西島和俊、森本正敏、北嶋修司
- Organizer
  第35回九州実験動物研究会総会
- Data Source
  KAKENHI-PROJECT-17K07138
[Presentation] パルス電界印加によるウサギ精子の先体反応の誘導2017
- Author(s)
  白石将平、猪原　哲、松久葉一、北嶋修司
- Organizer
  平成30年電気学会全国大会
- Data Source
  KAKENHI-PROJECT-17K07138
[Presentation] ウサギにおける効率的な受精卵作製の試み2017
- Author(s)
  松久葉一、秋吉俊明、松尾　完、塩見雅志、森本正敏、北嶋修司
- Organizer
  第35回動物生殖工学研究会
- Data Source
  KAKENHI-PROJECT-17K07138
[Presentation] ウサギにおける生殖工学技術の現状と今後の課題2017
- Author(s)
  北嶋修司、松久葉一、西島和俊、森本正敏
- Organizer
  第51回日本実験動物技術者協会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K07138
[Presentation] Increased hepatic expression of endothelial lipase inhibits cholesterol diet induced hypercholesterolemia and atherosclerosis in transgenic rabbits2017
- Author(s)
  Chuan Wang, Kazutoshi Nishijima, Shuji Kitajima, Manabu Niimi, Hizhao Yan, Yajie Chen, Bo Ning, Fumikazu Matsuhisa, Enqi Liu, Jifeng Zhang, Y. Eugene Chen, Jianglin Fan.
- Organizer
  The 7th International Meeting on Rabbit Biotechnology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07138
[Presentation] ウサギ胚凍結におけるデバイスおよび凍結液の比較検討2016
- Author(s)
  松久葉一、秋吉俊明、新見　学、森本正敏、範　江林、北嶋修司
- Organizer
  第63回日本実験動物学会
- Place of Presentation
  ミューザ川崎（神奈川）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-25430091
[Presentation] クライオトップを用いたウサギ桑実胚の凍結における凍結保存液の検討2015
- Author(s)
  秋吉俊明、松久葉一、江里口理嘉、森本正敏、北嶋修司
- Organizer
  第33回九州実験動物研究会総会
- Place of Presentation
  九州大学（福岡）
- Year and Date
  2015-11-07
- Data Source
  KAKENHI-PROJECT-25430091

1. KITAJIMA Shuji (70284643)

# of Collaborated Projects: 3 results

# of Collaborated Products: 24 results
2. NISHIJIMA Kazutoshi (70435874)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. FAN Jianglin (60272192)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Niimi Manabu (80644898)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
5. MATSUDA Yukihisa (50157327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. チェンヤジェ (90867756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 范江霖

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Matsuhisa Fumikazu 松久 葉一

MATSUHISA Fumikazu 松久 葉一

Research Projects

Research Products

Co-Researchers

高感受性血小板産生の展望：巨核球系細胞に及ぼすストレスホルモンの作用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effects of ANGPTLs on dyslipidemia and atherosclerosis: analysis using gene-modified rabbits.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functions of apo A-V in atherosclerosis: a study of knockout rabbit model

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Improvement of reproductive technology in rabbit

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of freezing method of rabbit embryos for cryopreservation of laboratory rabbits as human disease models

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Macrophage‐derived MMP‐9 enhances the progression of atherosclerotic lesions and vascular calcification in transgenic rabbits2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Apolipoprotein CIII Deficiency Protects Against Atherosclerosis in Knockout Rabbits2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Macrophage-derived matrix metalloproteinase-1 enhances aortic aneurysm formation in transgenic rabbits.2019

Author(s)

Journal Title

Data Source

[Journal Article] Sex hormones affect endothelial lipase-mediated lipid metabolism and atherosclerosis2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Growing oocyte specific transcription-dependent de novo DNA methylation at the imprinted Zrsr1-DMR2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ウサギ精子凍結保存液における卵黄代替物としての大豆由来機能性改質レシチンに関する検討2018

Author(s)

Journal Title

Data Source

[Journal Article] Increased hepatic expression of endothelial lipase inhibits cholesterol diet induced hypercholesterolemia and atherosclerosis in transgenic rabbits2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] アポE欠損カイロミクロンレムナントはウサギの動脈硬化を促進させる2023

Author(s)

Organizer

Data Source

[Presentation] 中性脂肪代謝異常の新規疾患モデル：アポA-V欠損ウサギの樹立2023

Author(s)

Organizer

Data Source

[Presentation] Apolipoprotein CIII deficiency inhibits cholesterol diet-induced hyperlipidemia and atherosclerosis in knockout rabbits2021

Author(s)

Organizer

Data Source

Matsuhisa Fumikazu 松久葉一

MATSUHISA Fumikazu 松久葉一