Niwa Yuki 丹羽祐貴

Researcher Number	20756077
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院薬学研究科, 特任助教(常勤)
Affiliation (based on the past Project Information) *help	2018: 国立研究開発法人産業技術総合研究所, 生命工学領域, 産総研特別研究員 2017: 慶應義塾大学, 理工学部(矢上), 助教
Review Section/Research Field	Principal Investigator Functional biochemistry
Keywords	Principal Investigator 糖鎖生物学 / CRISPR/Cas9 / C-mannosylation / C型糖転移酵素 / DPY19 / 糖転移酵素 / C型糖修飾

Exploration and identification of novel C-mannosyltransferasePrincipal Investigator
- Principal Investigator
  
  Niwa Yuki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  National Institute of Advanced Industrial Science and Technology
  Keio University

All 2019 2018 2017

All Journal Article Presentation

[Journal Article] C-mannosylation of R-spondin2 activates Wnt/β-catenin signaling and migration activity in human tumor cells.2019
- Author(s)
  Mizuta, H., Kuga, K., Suzuki, T., Niwa, Y., Dohmae, N. & Simizu, S.
- Journal Title
  
  International Journal of Oncology
  
  Volume: - Pages: 2127-2138
- DOI
  10.3892/ijo.2019.4767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06137, KAKENHI-PROJECT-17K15094
[Journal Article] <i>C</i>-Mannosylation: Previous Studies and Future Research Perspectives2018
- Author(s)
  Niwa Yuki、Simizu Siro
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 30 Issue: 177 Pages: E231-E238
- DOI
  10.4052/tigg.1755.1E
- NAID
  130007521332
- ISSN
  0915-7352, 1883-2113
- Year and Date
  2018-11-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15094
[Journal Article] Topological analysis of DPY19L3, a human C-mannosyltransferase2018
- Author(s)
  Niwa Yuki、Nakano Yoshihiko、Suzuki Takehiro、Yamagishi Mizuo、Otani Kei、Dohmae Naoshi、Simizu Siro
- Journal Title
  
  The FEBS Journal
  
  Volume: 285 Issue: 6 Pages: 1162-1174
- DOI
  10.1111/febs.14398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15094
[Journal Article] Regulation of granulocyte colony-stimulating factor receptor-mediated granulocytic differentiation by C -mannosylation2018
- Author(s)
  Otani Kei、Niwa Yuki、Suzuki Takehiro、Sato Natsumi、Sasazawa Yukiko、Dohmae Naoshi、Simizu Siro
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 498 Issue: 3 Pages: 466-472
- DOI
  10.1016/j.bbrc.2018.02.210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15094, KAKENHI-PROJECT-16J40133, KAKENHI-PROJECT-18K15464
[Journal Article] Integrin β1 is an essential factor in vasculogenic mimicry of human cancer cells.2018
- Author(s)
  Kawahara, R., Niwa, Y. & Simizu, S.
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 8 Pages: 2490-2496
- DOI
  10.1111/cas.13693
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06137, KAKENHI-PROJECT-17K15094
[Journal Article] Dpy-19 like 3-mediated C-mannosylation and expression levels of RPE-spondin in human tumor cell lines2017
- Author(s)
  Morishita Shohei、Suzuki Takehiro、Niwa Yuki、Dohmae Naoshi、Simizu Siro
- Journal Title
  
  Oncology Letters
  
  Volume: 14 Issue: 2 Pages: 2537-2544
- DOI
  10.3892/ol.2017.6465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] レクチンによるエクソソーム送達システムの開発2018
- Author(s)
  丹羽祐貴、舘野浩章
- Organizer
  第37回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] Glucosyl-galactosyl-hydroxylation of CCN1 regulates its secretion2018
- Author(s)
  Ishizawa, Y., Niwa, Y., Suzuki, T., Dohmae, N. & Simizu, S.
- Organizer
  29th International Carbohydrate Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] Glucosyl-galactosyl-hydroxylation of CCN1regulates its secretion2018
- Author(s)
  Yudai Ishizawa, Yuki Niwa, Takehiro Suzuki, Naoshi Dohmae, Siro Simizu
- Organizer
  International Symposium on ER stress, glycosylation, homeostasis, and diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] Identification of molecular targets on inhibitory activity of cell proliferation by cytosporolide analogs2018
- Author(s)
  Otake, K., Muroi, M., Niwa, Y., Takao, K., Osada, H. & Simizu, S.
- Organizer
  The 9th Japan-Korea Chemical Biology Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] ヒトiPS細胞由来エクソソームのグライコーム解析2018
- Author(s)
  齊藤佐代子、箕嶋文、清井佳代、丹羽祐貴、舘野浩章
- Organizer
  第37回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] インテグリンβ1は血管擬態形成に重要な因子である2018
- Author(s)
  川原遼太、丹羽祐貴、清水史郎
- Organizer
  第27回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] R-spondin1におけるリン酸化の機能解析2018
- Author(s)
  西谷拓海、鈴木健裕、丹羽祐貴、三浦一輝、堂前直、清水史郎
- Organizer
  日本農芸化学会関東支部2018年度支部大会
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] R-spondin2のC型糖修飾はがんのバイオマーカーに成り得る2018
- Author(s)
  水田隼斗、丹羽祐貴、清水史郎
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] CCN1におけるglucosyl-galactosyl- hydroxylationの機能解析2018
- Author(s)
  石沢雄大、丹羽祐貴、鈴木健裕、堂前直、清水史郎
- Organizer
  第37回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] トポロジー解析によるDPY19L1のC-mannosyltransferase活性中心の探索2018
- Author(s)
  横山典弘、柳原凌太郎、三浦一輝、丹羽祐貴、清水史郎
- Organizer
  日本農芸化学会関東支部2018年度支部大会
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] C-mannosylationによるR-spondin2の機能制御2018
- Author(s)
  水田隼斗、丹羽祐貴、堂前直、清水史郎
- Organizer
  第22回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] Cytosporolide類の細胞増殖抑制活性における責任分子標的の同定2018
- Author(s)
  大竹慶祐、室井誠、丹羽祐貴、宮嵜奏、笹澤有紀子、長田裕之、清水史郎
- Organizer
  第22回日本がん分子標的治療学会学術総会
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] トポロジー解析によるDPY19L1の活性中心の探索2018
- Author(s)
  横山典弘、柳原凌太郎、小松良亮、三浦一輝、丹羽祐貴、清水史郎
- Organizer
  第37回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] Integrin β1 plays a crucial role on vasculogenic mimicry formation2017
- Author(s)
  Ryota Kawahara, Yuki Niwa, Siro Simizu
- Organizer
  AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] がん細胞の血管擬態形成におけるintegrin beta1の役割解析2017
- Author(s)
  川原遼太、丹羽祐貴、清水史郎
- Organizer
  第26回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] Premelanosome Protein (PMEL) is C-Mannosylated at W104, W153 and W1562017
- Author(s)
  Ryosuke Komatsu, Takehiro Suzuki, Yuki Niwa, Erina Shimizu, Naoshi Dohmae, Siro Simizu
- Organizer
  24th International Symposium on Glycoconjugates
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] メラノソーム関連タンパク質PMELにおけるC-mannosylationの解析2017
- Author(s)
  小松良亮、丹羽祐貴、鈴木健裕、清水映輪奈、堂前直、清水史郎
- Organizer
  第36回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] ヒトがん細胞における血管擬態はintegrin beta1依存的である2017
- Author(s)
  川原遼太、丹羽祐貴、清水史郎
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] C型糖修飾酵素DPY19L3のトポロジー解析と活性点の探索2017
- Author(s)
  丹羽祐貴、中野圭彦、鈴木健裕、山岸瑞生、大谷慧、堂前直、清水史郎
- Organizer
  第36回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] 顆粒球コロニー刺激因子受容体のC型糖修飾はその機能に重要である2017
- Author(s)
  丹羽祐貴、清水史郎
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K15094
[Presentation] Identification of membrane topology of human DPY19L3 reveals that C-terminal region is essential for C-mannosyltransferase activity2017
- Author(s)
  Yuki Niwa, Yoshihiko Nakano, Takehiro Suzuki, Mizuo Yamagishi, Kei Otani, Naoshi Dohmae, Siro Simizu
- Organizer
  24th International Symposium on Glycoconjugates
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15094

1. 清水史郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Niwa Yuki 丹羽 祐貴

Research Projects

Research Products

Co-Researchers

Exploration and identification of novel C-mannosyltransferasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] C-mannosylation of R-spondin2 activates Wnt/β-catenin signaling and migration activity in human tumor cells.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] <i>C</i>-Mannosylation: Previous Studies and Future Research Perspectives2018

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Topological analysis of DPY19L3, a human C-mannosyltransferase2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of granulocyte colony-stimulating factor receptor-mediated granulocytic differentiation by C -mannosylation2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Integrin β1 is an essential factor in vasculogenic mimicry of human cancer cells.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dpy-19 like 3-mediated C-mannosylation and expression levels of RPE-spondin in human tumor cell lines2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] レクチンによるエクソソーム送達システムの開発2018

Author(s)

Organizer

Data Source

[Presentation] Glucosyl-galactosyl-hydroxylation of CCN1 regulates its secretion2018

Author(s)

Organizer

Data Source

[Presentation] Glucosyl-galactosyl-hydroxylation of CCN1regulates its secretion2018

Author(s)

Organizer

Data Source

[Presentation] Identification of molecular targets on inhibitory activity of cell proliferation by cytosporolide analogs2018

Author(s)

Organizer

Data Source

[Presentation] ヒトiPS細胞由来エクソソームのグライコーム解析2018

Author(s)

Organizer

Data Source

[Presentation] インテグリンβ1は血管擬態形成に重要な因子である2018

Author(s)

Organizer

Data Source

[Presentation] R-spondin1におけるリン酸化の機能解析2018

Author(s)

Organizer

Data Source

[Presentation] R-spondin2のC型糖修飾はがんのバイオマーカーに成り得る2018

Author(s)

Organizer

Data Source

[Presentation] CCN1におけるglucosyl-galactosyl- hydroxylationの機能解析2018

Author(s)

Organizer

Data Source

Niwa Yuki 丹羽祐貴