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maeda yuka  前田 優香

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Maeda Yuka  前田 優香

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Researcher Number 20757223
Other IDs
Affiliation (Current) 2025: 国立研究開発法人国立がん研究センター, 研究所, ユニット長
Affiliation (based on the past Project Information) *help 2019 – 2020: 国立研究開発法人国立がん研究センター, 研究所, 主任研究員
2016 – 2018: 国立研究開発法人国立がん研究センター, 研究所, 研究員
2015: 国立研究開発法人国立がん研究センター, その他部局等, 研究員
Review Section/Research Field
Principal Investigator
Immunology / Tumor therapeutics
Keywords
Principal Investigator
免疫学 / 免疫療法 / 免疫抑制 / ステロイド / irAE / 免疫チェックポイント阻害剤 / 不応答 / 抗腫瘍免疫応答 / 悪性黒色腫 / 腫瘍免疫 / 制御性T細胞 / がん免疫療法
  • Research Projects

    (2 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (9 People)
  •  Effects of steroids on anti-tumor immune response induced by immune checkpoint inhibitorsPrincipal Investigator

    • Principal Investigator
      Maeda Yuka
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Immunology
    • Research Institution
      National Cancer Center Japan
  •  Development of novel cancer immunotherapy based on the release of immune anergic statePrincipal Investigator

    • Principal Investigator
      Maeda Yuka
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Tumor therapeutics
    • Research Institution
      National Cancer Center Japan

All 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

  • [Journal Article] The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies2020

    • Author(s)
      Kumagai S,Togashi Y,Kamada T,Sugiyama E,Nishinakamura H,Takeuchi Y,Vitaly K,Itahashi K,Maeda Y,Matsui S,Shibahara T,Yamashita Y,Irie T,Tsuge A,Fukuoka S,Kawazoe A,Udagawa H,Kirita K,Aokage K,Ishii G,Kuwata T,Nakama K,Kawazu M,Ueno T,Yamazaki N,Goto K,Tsuboi M,Mano H,Doi T,Shitara K,Nishikawa H
    • Journal Title

      Nature Immunology

      Volume: 21 Issue: 11 Pages: 1346-1358

    • DOI

      10.1038/s41590-020-0769-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08531, KAKENHI-PROJECT-20H03694, KAKENHI-PROJECT-18J21551, KAKENHI-PROJECT-18K07320, KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-17K15738, KAKENHI-PROJECT-17H06162, KAKENHI-PROJECT-16H06299
  • [Journal Article] CYBERTRACK2.0: zero-inflated model-based cell clustering and population tracking method for longitudinal mass cytometry data2020

    • Author(s)
      Minoura K*, Abe K*, Maeda Y, Nishikawa H, Shimamura T§
    • Journal Title

      Bioinformatics

      Volume: - Issue: 11 Pages: 873-873

    • DOI

      10.1093/bioinformatics/btaa873

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-19H05210, KAKENHI-PROJECT-17K15738, KAKENHI-PROJECT-17H06162, KAKENHI-PUBLICLY-20H04841, KAKENHI-PROJECT-20H04281, KAKENHI-PROJECT-20K21832
  • [Journal Article] Adult-Onset Anti-Citrullinated Peptide Antibody-Negative Destructive Rheumatoid Arthritis Is Characterized by a Disease-Specific CD8+ T Lymphocyte Signature2020

    • Author(s)
      Kelkka T, Savola P, Bhattacharya D, Huuhtanen J, Lonnberg T, Kankainen M, Paalanen K, Tyster M, Lepisto M, Ellonen P, Smolander J, Eldfors S, Yadav B, Khan S, Koivuniemi R, Sjowall C, Elo LL, Lahdesmaki H, Maeda Y, Nishikawa H, Leirisalo-Repo M, Sokka-Isler T, Mustjoki S.
    • Journal Title

      Front Immunol.

      Volume: -

    • DOI

      10.3389/fimmu.2020.578848

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15738
  • [Journal Article] Model-based clustering for flow and mass cytometry data with clinical information2020

    • Author(s)
      Abe K, Minoura K, Maeda Y, Nishikawa H, Shimamura T§
    • Journal Title

      BMC Bioinformatics

      Volume: 21(Suppl 13) Issue: S13 Pages: 393-393

    • DOI

      10.1186/s12859-020-03671-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21832, KAKENHI-PUBLICLY-19H05210, KAKENHI-PUBLICLY-20H04841, KAKENHI-PROJECT-20H04281, KAKENHI-PROJECT-17K15738, KAKENHI-PROJECT-17H06162
  • [Journal Article] Selective inhibition of low-affinity memory CD8+ T cells by corticosteroids2019

    • Author(s)
      Tokunaga Akihiro、Sugiyama Daisuke、Maeda Yuka、Warner Allison Betof、Panageas Katherine S.、Ito Sachiko、Togashi Yosuke、Sakai Chika、Wolchok Jedd D.、Nishikawa Hiroyoshi
    • Journal Title

      Journal of Experimental Medicine

      Volume: 216 Issue: 12 Pages: 2701-2713

    • DOI

      10.1084/jem.20190738

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22574, KAKENHI-PROJECT-17K15738, KAKENHI-PROJECT-17H06162
  • [Journal Article] がん免疫療法におけるT細胞応答の効果予測因子としての可能性2016

    • Author(s)
      前田優香
    • Journal Title

      医学の歩み がん標的分子と治療開発ー現状と将来

      Volume: 258 Pages: 465-470

    • Data Source
      KAKENHI-PROJECT-15H06878
  • [Journal Article] Two FOXP3(+)CD4(+) T cell subpopulations distinctly control the prognosis of colorectal cancers.2016

    • Author(s)
      Saito, T., Nishikawa, H., Wada, H., Nagano, Y., Sugiyama, D., Atarashi, K., Maeda, Y., Hamaguchi, M., Ohkura, N., Sato, E., Nagase, H., Nishimura, J., Yamamoto, H., Takiguchi, S., Tanoue, T., Suda, W., Morita, H., Hattori, M., Honda, K., Mori, M., Doki, Y., Sakaguchi, S.
    • Journal Title

      Nat. Med

      Volume: 22 Issue: 6 Pages: 679-684

    • DOI

      10.1038/nm.4086

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05791, KAKENHI-PROJECT-15H04744, KAKENHI-PROJECT-15H06878, KAKENHI-PROJECT-15H06880, KAKENHI-PROJECT-16K15551, KAKENHI-PROJECT-16H06295, KAKENHI-PROJECT-26290054
  • [Presentation] Elucidation of the antigen-specific immunosuppression mechanism in the tumor microenvironment2020

    • Author(s)
      前田優香
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K15738
  • [Presentation] がん免疫-基礎研究から臨床応用の可能性2018

    • Author(s)
      前田優香
    • Organizer
      第58回日本リンパ網内系学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K15738
  • [Presentation] 免疫抑制-制御性T細胞とステロイド2018

    • Author(s)
      前田優香
    • Organizer
      第28回日本色素細胞学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K15738
  • [Presentation] Predicting patient response to immune checkpoint therapies through deep immune profiling2017

    • Author(s)
      Yuka Maeda
    • Organizer
      Interstellar Initiative (The New York Academy of Science)
    • Place of Presentation
      The New York Academy of Science, US
    • Year and Date
      2017-03-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H06878
  • [Presentation] Cancer antigens recognized by CD8+ T cells that induce tumor regression2016

    • Author(s)
      前田優香
    • Organizer
      第31回名古屋国際癌治療シンポジウム
    • Place of Presentation
      愛知がんセンター、日本
    • Year and Date
      2016-02-13
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H06878
  • [Presentation] がん免疫療法におけるT細胞応答の効果予測因子としての可能性2016

    • Author(s)
      前田優香
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜、第4会場
    • Year and Date
      2016-10-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H06878
  • [Presentation] Regulatory T Cell-mediated Anergy Induction in Tumor-selfantigen-specific CD8+ T Cells2015

    • Author(s)
      前田優香
    • Organizer
      Society for Immunotherapy of Cancer 30th Anniversary Annual Meeting
    • Place of Presentation
      National Harbor, MD, US
    • Year and Date
      2015-11-04
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H06878
  • [Presentation] Cancer antigens recognized by CD8+ T cells which induce tumor regression2015

    • Author(s)
      前田優香
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H06878
  • 1.  YAMAZAKI Naoya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  MORI Taisuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  NISHINAKAMURA Hitomi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  板橋 耕太
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  冨樫 庸介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  島村 徹平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 7.  土岐 祐一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  永野 浩昭
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  森 正樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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