Miyamoto Shohei 宮本将平

… Alternative Names

宮本将平ミヤモトショウヘイ

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Researcher Number	20758536
Other IDs
Affiliation (Current)	2025: 東京慈恵会医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2025: 東京慈恵会医科大学, 医学部, 講師 2022 – 2023: 東京慈恵会医科大学, 医学部, 講師 2020 – 2022: 東京大学, 定量生命科学研究所, 特任講師 2018 – 2019: 東京大学, 医科学研究所, 特任助教 2016: 東京大学, 医科学研究所, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 48030:Pharmacology-related / Basic Section 42040:Laboratory animal science-related / Applied pharmacology Except Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 55020:Digestive surgery-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 腫瘍溶解性ウイルス / がん治療 / 免疫 / ゲノム編集 / ウイルス療法 / トランスレーショナルリサーチ / 遺伝子 / 癌 / ウィルス / エンテロウイルス / コクサッキーウイルス … More Except Principal Investigator … More 腫瘍溶解性ウイルス / がん指向性リポソーム / 膵癌 / リポソーム / 免疫療法 / 腫瘍溶解ウィルス / 食道癌 / ワクチン / ネオ抗原ペプチド / 胃癌 / 悪性腫瘍 / キメラ抗原受容体T細胞 / 免疫不全マウス / Met分解酵素 / CAR-T / METase / メチオニン分解酵素 / オンコレトロウイルスベクター / レンチウイルスベクター / 麻疹ウイルスベクター / キメラ抗原受容体遺伝子導入T細胞療法 / CAR-T療法 / リンパ性悪性腫瘍 / 耐性克服 / 腫瘍特異的代謝 / バイスタンダー効果 / 腫瘍特異的栄養要求性 / 腫瘍溶解ウイルス療法 / 難治性腫瘍 / グリオブラストーマ Less

癌指向性リポソームを用いた腫瘍溶解性ウイルス療法のブレイクスルーPrincipal Investigator
- Principal Investigator
  
  宮本将平
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Jikei University School of Medicine
進行・再発胃がんに対するがん指向性リポソームを利用した腫瘍溶解ウイルス療法の開発
- Principal Investigator
  
  原圭吾
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Jikei University School of Medicine
ネオ抗原ペプチドを用いた胃癌に対する革新的個別化ワクチンの開発
- Principal Investigator
  
  藤崎宗春
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
腫瘍溶解ウイルス併用免疫療法による進行再発食道癌に対する革新的治療の開発
- Principal Investigator
  
  谷島雄一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Jikei University School of Medicine
がん指向性リポソームによる遺伝子制御を利用した膵癌腫瘍溶解性ウイルス療法の開発
- Principal Investigator
  
  百田禎郎
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Jikei University School of Medicine
免疫刺激性腫瘍溶解性ウイルス療法の抗腫瘍免疫機構の解明とその治療応用Principal Investigator
- Principal Investigator
  
  宮本将平
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  The University of Tokyo
Development of multi-drug immunotherapy using anti-fibrotic peptide and oncolytic virus for pancreatic cancer
- Principal Investigator
  
  緒方久修
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kyushu University
Development of evolutional gene modified T cell transfusion therapy using novel and self-developed measles viral vector
- Principal Investigator
  
  Tani Kenzaburo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  The University of Tokyo
Armored oncolytic virus targeting tumor-specific amino acid metabolism
- Principal Investigator
  
  Soda Yasushi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  The University of Tokyo
膵癌に対する抗線維化療法を併用した新規腫瘍溶解性ウイルス免疫療法の開発
- Principal Investigator
  
  緒方久修
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kyushu University
Elucidation of cytotoxicity mechanism for oncolytic virus by genome-editing high-throughput knockoutPrincipal Investigator
- Principal Investigator
  
  Miyamoto Shohei
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Jikei University School of Medicine
  The University of Tokyo
Development of novel recombinant oncolytic virotherapy which has superiority in safety and antitumor efficacyPrincipal Investigator
- Principal Investigator
  
  Miyamoto Shohei
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  The University of Tokyo

All 2023 2021 2020 2019 2018

All Journal Article Presentation Patent

[Journal Article] Development of New Oncolytic Virotherapy Targeting Breast Cancer Using Coxsackievirus B32021
- Author(s)
  SAGARA MIYAKO、MIYAMOTO SHOHEI、ITOH SHUN、SODA YASUSHI、TANI KENZABURO
- Journal Title
  
  Anticancer Research
  
  Volume: 41 Issue: 1 Pages: 81-89
- DOI
  10.21873/anticanres.14753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16500
[Journal Article] A pilot study to establish human T‐cell leukemia virus type 1 (HTLV‐1) carrier model using common marmoset ( Callithrix jacchus )2020
- Author(s)
  Hirose Lisa、Hiramoto Takafumi、Tian Yamin、Kohara Hiroshi、Kobayashi Seiichiro、Nagai Etsuko、Denda Tamami、Tanaka Yukihisa、Ota Yasunori、Jiyuan Liao、Miyamoto Shohei、Miura Yoshie、Hijikata Yasuki、Soda Yasushi、Inoue Takashi、Okahara Norio、Itoh Toshio、Sasaki Erika、Tojo Arinobu、Uchimaru Kaoru、Tani Kenzaburo
- Journal Title
  
  Journal of Medical Primatology
  
  Volume: 49 Issue: 2 Pages: 86-94
- DOI
  10.1111/jmp.12454
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16500, KAKENHI-PROJECT-17H01547
[Journal Article] Photocontrollable mononegaviruses2019
- Author(s)
  Tahara M, Takishima Y, Miyamoto S, Nakatsu Y, Someya K, Sato M, Tani K, Takeda M
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 116 Issue: 24 Pages: 11587-11589
- DOI
  10.1073/pnas.1906531116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07768, KAKENHI-PROJECT-19K16500, KAKENHI-PROJECT-17H01547
[Journal Article] KLF1 Mutation E325K Induces Cell-cycle Arrest in Erythroid Cells Differentiated from Congenital Dyserythropoietic Anemia (CDA) Patient-specific Induced Pluripotent Stem Cells.2019
- Author(s)
  Kohara H, Utsugisawa T, Sakamoto C, Hirose L, Ogawa Y, Ogura H, Sugawara A, Aoki T, Iwasaki T, Asai T, Doisaki S, Okuno Y, Muramatsu H, Abe T, Kurita R, Miyamoto S, Sakuma T, Shiba M, Yamamoto T, Ohga S, Yoshida K, Ogawa S, Ito E, Kojima S, Kanno H, Tani K.
- Journal Title
  
  Exp Hematol.
  
  Volume: 73 Pages: 25-37
- DOI
  10.1016/j.exphem.2019.03.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-17H01547, KAKENHI-PROJECT-19K16500, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-16K10041, KAKENHI-PROJECT-16K19181
[Journal Article] Extremely low organ toxicity and strong antitumor activity of miR-34-regulated oncolytic coxsackievirus B3.2019
- Author(s)
  Jia, Y., Miyamoto, S., Soda, Y., Takishima, Y., Sagara, M., Liao, J., Hirose-Yotsuya, L., Hijikata, Y., Miura, Y., Hara, K., Iwanaga, A., Ota, Y., Tani, K.
- Journal Title
  
  Mol Ther Oncolytics.
  
  Volume: 12 Pages: 246-258
- DOI
  10.1016/j.omto.2019.01.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01547, KAKENHI-PROJECT-19K16500, KAKENHI-PROJECT-16K19181
[Journal Article] A novel combination therapy for human oxaliplatin-resistant colorectal cancer using oxaliplatin and coxsackievirus A11.2018
- Author(s)
  Wang, B., Ogata, H., Takishima, Y., Miyamoto, S., Inoue, H., Kuroda, M., Yamada, K., Hijikata, Y., Murahashi, M., Shimizu, H., Okazaki, T., Nakanishi, Y., Tani, K.
- Journal Title
  
  Anticancer Res.
  
  Volume: 38 Issue: 11 Pages: 6121-6126
- DOI
  10.21873/anticanres.12963
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H01547, KAKENHI-PROJECT-16H05200, KAKENHI-PROJECT-16K19181, KAKENHI-PROJECT-17K09464
[Patent] 鎌状赤血球症の改善及び／又は予防剤2019
- Inventor(s)
  谷憲三朗、曽田泰、廖紀元、宮本将平、河田聡史、富岡基康、児玉健
- Industrial Property Rights Holder
  谷憲三朗、曽田泰、廖紀元、宮本将平、河田聡史、富岡基康、児玉健
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-170764
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-19K16500
[Presentation] Combination therapy of immunostimulatory CVB3 and PD-L1 blockade works to enhance anti-cancer efficacy.2023
- Author(s)
  Shohei Miyamoto, Miyako Sagara, Shun Ito, Yasushi Soda, Tetsu Akiyama, Mutsunori Murahashi, Kenzaburo Tani.
- Organizer
  第29回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-23K07383
[Presentation] 胃癌に対するコクサッキーウイルスB群3型を用いたウイルス療法の開発.2023
- Author(s)
  坂下裕紀、宮本将平、小林由紀子、相良京、伊藤駿、谷憲三朗、村橋睦了.
- Organizer
  第１回日本ウイルス療法学会学術集会
- Data Source
  KAKENHI-PROJECT-23K07383
[Presentation] Combination therapy of immunostimulatory oncolytic coxsackievirus B3 and PD-L1 blockade works synergistically to enhance anti-cancer efficacy.2023
- Author(s)
  Shohei Miyamoto, Miyako Sagara, Shun Ito, Akira Sakamoto, Yasushi Soda, Tetsu Akiyama, Mutsunori Murahashi, Kenzaburo Tani.
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K07383
[Presentation] 免疫刺激性遺伝子改変コクサッキーウイルス療法の開発.2023
- Author(s)
  宮本将平、相良京、伊藤駿、坂下裕紀、小林由紀子、秋山徹、谷憲三朗、村橋睦了.
- Organizer
  第１回日本ウイルス療法学会学術集会
- Data Source
  KAKENHI-PROJECT-23K07383
[Presentation] A novel Echovirus 4 shows noticeable oncolytic activity against esophageal cancer.2021
- Author(s)
  Sakamoto A, Yasunari K, Inoue H, Miyamoto S, Sagara M, Ito S, Soda Y, Akiyama T, Tani K
- Organizer
  第27回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16500
[Presentation] A novel Echovirus 4 shows remarkable oncolytic capacity against esophageal cancer.2021
- Author(s)
  Sakamoto A, Inoue H, Miyamoto S, Sagara M, Ito S, Soda Y, Akiyama T, Tani K
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16500
[Presentation] Development of gene modified oncolytic coxsackievirus for clinical trial.2021
- Author(s)
  Ito S, Miyamoto S, Sagara M, Sakamoto A, Soda Y, Akiyama T, Tani K
- Organizer
  第27回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16500
[Presentation] Development and manufacturing of miRNA-regulated oncolytic virus for clinical trial.2021
- Author(s)
  Ito S, Miyamoto S, Sagara M, Sakamoto A, Soda Y, Akiyama T, Tani K
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16500
[Presentation] Analysis of Human iPSCs Generated by a Non-Integrating Measles Virus Vector.2019
- Author(s)
  Liao J, Soda Y, Sugawara A, Miura Y, Hiramoto T, Tahara M, Takishima Y, Hijikata Y, Miyamoto S, Takeda M, Tani K.
- Organizer
  American Society of Gene and Cell Therapy 22nd Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16500
[Presentation] Preclinical Evaluation of Novel Chondroitin Sulfate Polymer coated Oncolytic Measles virus therapy.2019
- Author(s)
  Miura Y, Takishima Y, Miyamoto S, Jia Y, Sagara M, Soda Y, Tani K.
- Organizer
  第25回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16500
[Presentation] Pilot study to detect circulating tumor cells in human peripheral blood using 5-aminolevulinic acid.2019
- Author(s)
  Hirose L, Kohara H, Sagara M, Miura Y, Hijikata Y, Soda Y, Miyamoto S, Takahashi S, Shinozaki M, Denda T, Tanaka Y, Ota Y, Watanabe E, Tanaka T, Nakajima M, Kiniwa S, Okuyama R, Fukuhara H, Inoue K, Namikawa T, Hanazaki K, Tani K.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16500
[Presentation] Measles virus vector is a promising tool for T-cell engineering and establishing naive-like iPSCs.2019
- Author(s)
  Liao J, Soda Y, Sugawara A, Miura Y, Hiramoto T, Tahara M, Takishima Y, Miyamoto S, Hijikata Y, Takeda M, Tani K.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16500
[Presentation] 5-ALAを用いた末梢血循環がん細胞の検出法確立にむけたパイロット研究2019
- Author(s)
  廣瀬理沙、小原洋志、相良京、三浦由恵、石井有美子、土方康基、曽田泰、宮本将平、廖紀元、高橋聡、篠崎大、大田泰徳、渡辺恵理、田中徹、中島元夫、木庭幸子、奥山隆平、福原秀雄、井上啓史、並川努、花﨑和弘、谷憲三朗
- Organizer
  第６回PDDTフォーラム
- Data Source
  KAKENHI-PROJECT-19K16500
[Presentation] Direct induction of naive-like human induced pluripotent stem cells (iPSCs) by a non-integrating measles virus vector.2019
- Author(s)
  Liao J, Soda Y, Sugawara A, Miura Y, Hiramoto T, Tahara M, Takishima Y, Hijikata Y, Miyamoto S, Takeda M, Tani K.
- Organizer
  第25回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16500
[Presentation] Development of novel miRNA-regulated oncolytic virotherapy for malignant tumors.2019
- Author(s)
  Sagara M, Miyamoto S, Ito S, Soda Y, Miura Y, Hijikata Y, Shimizu H, Tani K.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K16500
[Presentation] 5-ALAを用いた末梢血循環がん細胞の検出法確立にむけたパイロット研究2019
- Author(s)
  廣瀬理沙、小原洋志、相良京、三浦由恵、土方康基、曽田泰、宮本将平、廖紀元、高橋聡、篠崎大、大田泰徳、渡辺恵理、田中徹、中島元夫、木庭幸子、奥山隆平、福原秀雄、井上啓史、並川努、花﨑和弘、谷憲三朗
- Organizer
  第９回ポルフィリン-ALA学会
- Data Source
  KAKENHI-PROJECT-19K16500
[Presentation] A novel combination therapy using oxaliplatin and Coxackievirus A11 against human colorectal cancer.2019
- Author(s)
  Ogata H, Wang B, Miyamoto S, Takishima Y, Sagara M, Tani K.
- Organizer
  第25回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16500
[Presentation] Development of microRNA-regulated oncolytic Coxsackievirus for clinical trial.2019
- Author(s)
  Miyamoto S, Sagara M, Jia Y, Soda Y, Miura Y, Shimizu H, Tani K.
- Organizer
  第25回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16500
[Presentation] Dual microRNA Engineered Oncolytic Coxsackievirus Virotherapy for Clinical Trial.2019
- Author(s)
  Miyamoto S, Jia Y, Soda Y, Sagara M, Liao J, Hirose L, Hijikata Y, Hara K, Iwanaga A, Tani K
- Organizer
  American Society of Gene and Cell Therapy 22nd Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16500
[Presentation] Inhibition of sickling by 5-aminolevulinic acid in sickle cell disease mouse models.2019
- Author(s)
  Kodama K, Soda Y, Liao J, Miyamoto S, Deguchi T, Fujine K, Sakata H, Tomioka M, Tani K.
- Organizer
  7th International ALA and Porphyrin Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16500
[Presentation] The current preparative status of oncolytic coxsackievirotherapy toward clinical trial.2018
- Author(s)
  Shohei Miyamoto
- Organizer
  第24回日本遺伝子細胞治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K19181

1. 村橋睦了 (20422420)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. 百田禎郎 (90820366)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. 増田隆洋 (40649092)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 矢野文章 (80318005)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 谷島雄一郎 (80385335)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. Soda Yasushi (00361618)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 緒方久修 (70432945)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 大西秀哉 (30553276)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 大内田研宙 (20452708)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 松沢厚 (80345256)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 原圭吾 (90974717)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 藤崎宗春 (50597979)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 佐藤和秀 (50974763)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 高橋慶太 (70795096)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 宇野耕平 (80899386)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. 黒河内喬範 (90846601)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. Tani Kenzaburo (00183864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. 廖紀元 (90781857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 坂下裕紀 (80911586)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. MUTSUNORI Iga

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
21. TAHARA Maino

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 小川誠司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Miyamoto Shohei 宮本 将平

宮本 将平 ミヤモト ショウヘイ

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癌指向性リポソームを用いた腫瘍溶解性ウイルス療法のブレイクスルーPrincipal Investigator

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免疫刺激性腫瘍溶解性ウイルス療法の抗腫瘍免疫機構の解明とその治療応用Principal Investigator

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Elucidation of cytotoxicity mechanism for oncolytic virus by genome-editing high-throughput knockoutPrincipal Investigator

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Development of novel recombinant oncolytic virotherapy which has superiority in safety and antitumor efficacyPrincipal Investigator

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[Journal Article] Development of New Oncolytic Virotherapy Targeting Breast Cancer Using Coxsackievirus B32021

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[Journal Article] A pilot study to establish human T‐cell leukemia virus type 1 (HTLV‐1) carrier model using common marmoset ( Callithrix jacchus )2020

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[Journal Article] Photocontrollable mononegaviruses2019

Miyamoto Shohei 宮本将平

宮本将平ミヤモトショウヘイ