Shima Kosuke 島孝佑

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Kosuke Shima 島孝佑

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Researcher Number	20770613
Affiliation (Current)	2025: 金沢大学, 医学系, 協力研究員
Affiliation (based on the past Project Information) *help	2018: 金沢大学, 医学系, 協力研究員 2016 – 2017: 金沢大学, 附属病院, 医員
Review Section/Research Field	Principal Investigator Metabolomics
Keywords	Principal Investigator 栄養学 / 糖尿病 / 非アルコール性脂肪肝炎 / ヘパトカイン / LECT2 / 非アルコール性脂肪肝

The effect of hepatokine LECT2 on the pathphysiology of NASHPrincipal Investigator
- Principal Investigator
  
  Kosuke Shima
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kanazawa University

All 2018 2017 2016

All Journal Article Presentation

[Journal Article] Ursodeoxycholic acid potentiates dipeptidyl peptidase-4 inhibitor sitagliptin by enhancing glucagon-like peptide-1 secretion in patients with type 2 diabetes and chronic liver disease: a pilot randomized controlled and add-on study2018
- Author(s)
  K. R. Shima, T. Ota, K. I. Kato, Y. Takeshita, H. Misu, S. Kaneko and T. Takamura
- Journal Title
  
  BMJ Open Diabetes Res Care
  
  Volume: 6 Issue: 1 Pages: e000469-e000469
- DOI
  10.1136/bmjdrc-2017-000469
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-16K19533, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-16H03035
[Journal Article] Heterogeneous nature of diabetes in a family with a gain-of-function mutation in the ATP-binding cassette subfamily C member 8 (ABCC8) gene2018
- Author(s)
  Kosuke Robert Shima, Rika Usuda, Takeshi Futatani, Hiroshi Akahori, Shuichi Kaneko, Tohru Yorifuji, and Toshinari Takamura
- Journal Title
  
  Endocr J
  
  Volume: 65 Issue: 10 Pages: 1055-1059
- DOI
  10.1507/endocrj.EJ18-0054
- NAID
  130007501408
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19533
[Journal Article] Rationale and design of a multicenter placebo-controlled double-blind randomized trial to evaluate the effect of empagliflozin on endothelial function: the EMBLEM trial.2017
- Author(s)
  Tanaka A, Shimabukuro M, Okada Y, Taguchi I, Yamaoka-Tojo M, Tomiyama H, Teragawa H, Sugiyama S, Yoshida H, Sato Y, Kawaguchi A, Ikehara Y, Machii N, Maruhashi T, Shima KR, Takamura T, Matsuzawa Y, Kimura K, Sakuma M, Oyama JI, Inoue T, Higashi Y, Ueda S, Node K; EMBLEM Trial Investigators.
- Journal Title
  
  Cardiovasc Diabetol.
  
  Volume: 印刷中 Issue: 1 Pages: 48-48
- DOI
  10.1186/s12933-017-0532-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01389, KAKENHI-PROJECT-16K19533
[Journal Article] 元気の出る糖尿病チームのつくり方2016
- Author(s)
  島　孝佑、篁　俊成
- Journal Title
  
  糖尿病診療マスター
  
  Volume: 2 Pages: 121-121
- Data Source
  KAKENHI-PROJECT-16K19533
[Journal Article] Why is hippocampal CA1 especially vulnerable to Ischemia?2016
- Author(s)
  Hanbai Liang, Shota Kurimoto, Kosuke R Shima, Daiki Shimizu, Tsuguhito Ota, Yoshio Minabe, Tetsumori Yamashima
- Journal Title
  
  SOJ Biochemistry
  
  Volume: 2 Issue: 1 Pages: 1-7
- DOI
  10.15226/2376-4589/2/1/00108
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01814, KAKENHI-PROJECT-16K19533
[Journal Article] Role of GPR40 for fish oil PUFA-mediated BDNF synthesis in the monkey hippocampus2016
- Author(s)
  Arumugam Mathivanan, Yoshio Minabe, Tsuguhito Ota, Naoto Nagata, Kosuke R. Shima, Tetsumori Yamashima
- Journal Title
  
  J Alzheimers Dis Parkinsonism
  
  Volume: 6 Issue: 01 Pages: 1-12
- DOI
  10.4172/2161-0460.1000213
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01814, KAKENHI-PROJECT-16K19533
[Presentation] ウルソデオキシコール酸の単独・DPP4阻害薬との併用療法が慢性肝疾患合併2型糖尿病の体重、血糖、インクレチン分泌に及ぼす効果2018
- Author(s)
  島　孝佑、太田嗣人、竹下有美枝、御簾博文、金子周一、篁　俊成
- Organizer
  第5回肝臓と糖尿病・代謝研究会
- Data Source
  KAKENHI-PROJECT-16K19533
[Presentation] 骨髄癌腫症に至った治療抵抗性悪性パラガングリオーマの一剖検例2017
- Author(s)
  島孝佑、迫佐央理、御簾博文、篁俊成
- Organizer
  第27回臨床内分泌代謝Update
- Data Source
  KAKENHI-PROJECT-16K19533
[Presentation] Comparison of acarbose versus voglibose monotherapy on GLP-1 secretion and postprandial dyslipidemia in patients with type 2 diabetes2017
- Author(s)
  Kosuke R SHIMA, Rika USUDA, Yinhua NI, Shuichi KANEKO, Toshinari TAKAMURA, Tsuguhito OTA
- Organizer
  International Diabetes Federation 2017 Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19533
[Presentation] The effect of ursodeoxycholic acid added to dipeptidyl peptidase-4 inhibitor on GLP-1 secretion and glucose tolerance in subjects with type 2 diabetes.2017
- Author(s)
  Kosuke R Shima, Yumie Takeshita, Hirofumi Misu, Tsuguhito Ota, Toshinari Takamura
- Organizer
  Keystone symposia Bile Acid Receptors as Signal Integrators in Liver and Metabolism
- Place of Presentation
  Montrey, CA, US
- Year and Date
  2017-03-08
- Data Source
  KAKENHI-PROJECT-16K19533
[Presentation] The effect of ursodeoxycholic acid added to dipeptidyl peptidase-4 inhibitor on GLP-1 secretion and glucose tolerance in subjects with type 2 diabetes.2017
- Author(s)
  Kosuke R Shima, Yumie Takeshita, Hirofumi Misu, Tsuguhito Ota, Toshinari Takamura
- Organizer
  77th Scientific Sessions of the American Diabetes Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19533
[Presentation] Comparison of acarbose monotherapy and voglibose monotherapy on incretin secretion and postprandial dyslipidemia in patients with type 2 diabetes: a randomized controlled study2016
- Author(s)
  KOSUKE R SHIMA, RIKA USUDA, YINHUA NI, SHUICHI KANEKO, TOSHINARI TAKAMURA, TSUGUHITO OTA
- Organizer
  11th IDF-WPR congress 2016 and AASD scientific meeting
- Place of Presentation
  Taipei
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-16K19533
[Presentation] 胆汁酸の単独・DPP4阻害薬との併用療法が2型糖尿病の体重、血糖、インクレチン分泌に及ぼす効果2016
- Author(s)
  島孝佑、竹下有美枝、御簾博文、篁俊成
- Organizer
  第37回日本肥満学会
- Place of Presentation
  東京
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-16K19533
[Presentation] ２型糖尿病患者に対するウルソデオキシコール酸及びDPP-4阻害薬の単独・併用が血糖コントロールと活性型GLP-１値に及ぼす効果2016
- Author(s)
  島孝佑、竹下有美枝、圓山泰史、御簾博文、篁俊成
- Organizer
  第59回糖尿病学会年次学術総会
- Place of Presentation
  京都
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-16K19533

1. 東條美奈子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 山嶋哲盛

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 御簾博文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shima Kosuke 島 孝佑

Kosuke Shima 島 孝佑

Research Projects

Research Products

Co-Researchers

The effect of hepatokine LECT2 on the pathphysiology of NASHPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Ursodeoxycholic acid potentiates dipeptidyl peptidase-4 inhibitor sitagliptin by enhancing glucagon-like peptide-1 secretion in patients with type 2 diabetes and chronic liver disease: a pilot randomized controlled and add-on study2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Heterogeneous nature of diabetes in a family with a gain-of-function mutation in the ATP-binding cassette subfamily C member 8 (ABCC8) gene2018

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Rationale and design of a multicenter placebo-controlled double-blind randomized trial to evaluate the effect of empagliflozin on endothelial function: the EMBLEM trial.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 元気の出る糖尿病チームのつくり方2016

Author(s)

Journal Title

Data Source

[Journal Article] Why is hippocampal CA1 especially vulnerable to Ischemia?2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of GPR40 for fish oil PUFA-mediated BDNF synthesis in the monkey hippocampus2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] ウルソデオキシコール酸の単独・DPP4阻害薬との併用療法が慢性肝疾患合併2型糖尿病の体重、血糖、インクレチン分泌に及ぼす効果2018

Author(s)

Organizer

Data Source

[Presentation] 骨髄癌腫症に至った治療抵抗性 悪性パラガングリオーマの一剖検例2017

Author(s)

Organizer

Data Source

[Presentation] Comparison of acarbose versus voglibose monotherapy on GLP-1 secretion and postprandial dyslipidemia in patients with type 2 diabetes2017

Author(s)

Organizer

Data Source

[Presentation] The effect of ursodeoxycholic acid added to dipeptidyl peptidase-4 inhibitor on GLP-1 secretion and glucose tolerance in subjects with type 2 diabetes.2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] The effect of ursodeoxycholic acid added to dipeptidyl peptidase-4 inhibitor on GLP-1 secretion and glucose tolerance in subjects with type 2 diabetes.2017

Author(s)

Organizer

Data Source

[Presentation] Comparison of acarbose monotherapy and voglibose monotherapy on incretin secretion and postprandial dyslipidemia in patients with type 2 diabetes: a randomized controlled study2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 胆汁酸の単独・DPP4阻害薬との併用療法が2型糖尿病の体重、血糖、インクレチン分泌に及ぼす効果2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ２型糖尿病患者に対するウルソデオキシコール酸及びDPP-4阻害薬の単独・併用が血糖コントロールと活性型GLP-１値に及ぼす効果2016

Author(s)

Organizer

Shima Kosuke 島孝佑

Kosuke Shima 島孝佑

[Presentation] 骨髄癌腫症に至った治療抵抗性悪性パラガングリオーマの一剖検例2017