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NISHIMURA KEISUKE  西村 啓佑

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Nishimura Keisuke  西村 啓佑

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Researcher Number 20771497
Other IDs
Affiliation (Current) 2025: 神戸大学, 医学部附属病院, 特定助教
Affiliation (based on the past Project Information) *help 2023: 神戸大学, 医学部附属病院, 特定助教
2020 – 2023: 公益財団法人大原記念倉敷中央医療機構(臨床医学研究所 臨床医学研究開発部), クリニカルサイエンスリサーチグループ, 研究員
2016 – 2019: 神戸大学, 医学研究科, 医学研究員
Review Section/Research Field
Principal Investigator
Collagenous pathology/Allergology
Except Principal Investigator
Basic Section 57060:Surgical dentistry-related / Basic Section 58010:Medical management and medical sociology-related
Keywords
Principal Investigator
免疫学 / 骨髄由来抑制細胞 (MDSC) / 骨髄由来抑制細胞(MDSC) / 代謝 / 骨髄由来抑制細胞 / 関節リウマチ
Except Principal Investigator
自己免疫疾患モデ ル / 好中球 / 自己免疫疾患モデル / ESSDAI … More / シェーグレン症候群 / QOL / 主観的幸福度 / 関節リウマチ Less
  • Research Projects

    (3 results)
  • Research Products

    (26 results)
  • Co-Researchers

    (12 People)
  •  好中球に着眼したシェーグレン症候群の新規病理分類提案と治療薬探索

    • Principal Investigator
      後藤 育子
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Kobe University
  •  The fluctuation in subjective well-being of patients with early rheumatoid arthritis

    • Principal Investigator
      蔭山 豪一
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58010:Medical management and medical sociology-related
    • Research Institution
      Hyogo Prefectural Amagasaki General Medical Center
  •  Novel treatment of autoimmune diseases using myeloid-derived suppressor cellPrincipal Investigator

    • Principal Investigator
      Nishimura Keisuke
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Collagenous pathology/Allergology
    • Research Institution
      Kobe University

All 2020 2019 2018 2017 2016

All Journal Article Presentation

  • [Journal Article] Shoulder ultrasound and serum lactate dehydrogenase predict inadequate response to glucocorticoid treatment in patients with polymyalgia rheumatica.2020

    • Author(s)
      Ayano M, Arinobu Y, Tsukamoto H, Ota SI, Misaki K, Nishimura K, Kimoto Y, Mitoma H, Akahoshi M, Akashi K, Horiuchi T, Niiro H.
    • Journal Title

      Rheumatology International

      Volume: - Issue: 7 Pages: 1101-1109

    • DOI

      10.1007/s00296-020-04512-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K19599, KAKENHI-PROJECT-19K08910, KAKENHI-PROJECT-19K17887, KAKENHI-PROJECT-19H03564
  • [Journal Article] Genetic and clinical prediction models for the efficacy and hepatotoxicity of methotrexate in patients with rheumatoid arthritis: a multicenter cohort study2019

    • Author(s)
      Onishi Akira、Kamitsuji Shigeo、Nishida Miwa、Uemura Yuko、Takahashi Miho、Saito Toshiharu、Yoshida Yuichiro、Kobayashi Masaki、Kawate Mizuho、Nishimura Keisuke、Misaki Kenta、Nobuhara Yumiko、Nakazawa Takashi、Hatachi Saori、Tsuji Goh、Morinobu Akio、Kumagai Shunichi
    • Journal Title

      The Pharmacogenomics Journal

      Volume: - Issue: 3 Pages: 433-442

    • DOI

      10.1038/s41397-019-0134-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K16150, KAKENHI-PROJECT-16K19599
  • [Journal Article] Additive effects of inhibiting both mTOR and glutamine metabolism on the arthritis in SKG mice2019

    • Author(s)
      Ueda Yo、Saegusa Jun、Okano Takaichi、Sendo Sho、Yamada Hirotaka、Nishimura Keisuke、Morinobu Akio
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 6374-6374

    • DOI

      10.1038/s41598-019-42932-1

    • NAID

      120006624233

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08387, KAKENHI-PROJECT-16K19599
  • [Journal Article] Tofacitinib facilitates the expansion of myeloid-derived suppressor cells and ameliorates interstitial lung disease in SKG mice.2019

    • Author(s)
      Sendo S, Saegusa J, Yamada H, Nishimura K, Morinobu A.
    • Journal Title

      Arthritis Research Therapy

      Volume: 6 Issue: 1 Pages: 184-184

    • DOI

      10.1186/s13075-019-1963-2

    • NAID

      120006713587

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K19599, KAKENHI-PROJECT-18K16148
  • [Journal Article] Efficacy of Plasma Exchange in Anti‐neutrophil Cytoplasmic Antibody‐associated Vasculitis2019

    • Author(s)
      Nishimura Keisuke、Waki Daisuke、Kadoba Keiichiro、Mukoyama Hiroki、Yokota Toshihiko、Murabe Hiroyuki
    • Journal Title

      Therapeutic Apheresis and Dialysis

      Volume: 29 Issue: 3 Pages: 248-252

    • DOI

      10.1111/1744-9987.12828

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Journal Article] Radiological fibrosis score is strongly associated with worse survival in rheumatoid arthritis-related interstitial lung disease2018

    • Author(s)
      Ito Yuhei、Arita Machiko、Kumagai Shogo、Takei Reoto、Noyama Maki、Tokioka Fumiaki、Nishimura Keisuke、Koyama Takashi、Tachibana Hiromasa、Ishida Tadashi
    • Journal Title

      Modern Rheumatology

      Volume: 13 Issue: 1 Pages: 1-7

    • DOI

      10.1080/14397595.2018.1442170

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Journal Article] Radiographic fibrosis score predicts survival in systemic sclerosis-associated interstitial lung disease.2018

    • Author(s)
      Takei R, Arita M, Kumagai S, Ito Y, Tokioka F, Koyama T, Saito R, Nishimura K, Tokumasu H, Ishida T.
    • Journal Title

      Respirology

      Volume: 23 Issue: 4 Pages: 385-391

    • DOI

      10.1111/resp.13175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Journal Article] Very high frequency of fragility fractures associated with high-dose glucocorticoids in postmenopausal women: A retrospective study.2017

    • Author(s)
      Kageyama G, Okano T, Yamamoto Y, Nishimura K, Sugiyama D, Saegusa J, Tsuji G, Kumagai S, Morinobu A.
    • Journal Title

      Bone Reports

      Volume: 6 Pages: 3-8

    • DOI

      10.1016/j.bonr.2016.11.003

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Journal Article] 3-bromopyruvate ameliorate autoimmune arthritis by modulating Th17/Treg cell differentiation and suppressing dendritic cell activation.2017

    • Author(s)
      Okano T, Saegusa J, Nishimura K, Takahashi S, Sendo S, Ueda Y, Morinobu A
    • Journal Title

      Scientific Reports

      Volume: 7

    • NAID

      120006624239

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Journal Article] Serological and morphological prognostic factors in patients with interstitial pneumonia with autoimmune features.2017

    • Author(s)
      Ito Y, Arita M, Kumagai S, Takei R, Noyama M, Tokioka F, Nishimura K, Koyama T, Notohara K, Ishida T.
    • Journal Title

      BMC Pulm Med

      Volume: 14 Issue: 1

    • DOI

      10.1186/s12890-017-0453-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Journal Article] Expression and Functions of Immediate Early Response Gene X-1 (IEX-1) in Rheumatoid Arthritis Synovial Fibroblasts.2016

    • Author(s)
      Morinobu A, Tanaka S, Nishimura K, Takahashi S, Kageyama G, Miura Y, Kurosaka M, Saegusa J, Kumagai S.
    • Journal Title

      PLoS One

      Volume: 11 Issue: 10 Pages: e0164350-e0164350

    • DOI

      10.1371/journal.pone.0164350

    • NAID

      120005898575

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09525, KAKENHI-PROJECT-16K19599
  • [Journal Article] Knockout of endothelin type B receptor signaling attenuates bleomycin-induced skin sclerosis in mice.2016

    • Author(s)
      Akashi K, Saegusa J, Sendo S, Nishimura K, Okano T, Yagi K, Yanagisawa M, Emoto N, Morinobu A.
    • Journal Title

      Arthritis Res Ther.

      Volume: 18 Issue: 1 Pages: 113-113

    • DOI

      10.1186/s13075-016-1011-4

    • NAID

      120007135444

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09525, KAKENHI-PROJECT-16K19599
  • [Presentation] IgG4関連疾患の臨床所見と顎下腺超音波shear wave elastographyの関連2019

    • Author(s)
      西村啓佑、佐原朗子、水川薫、門場啓一郎、吉田知宏、脇大輔、村部浩之、横田敏彦
    • Organizer
      第47回 日本臨床免疫学会総会
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Presentation] PREDICTORS OF RELAPSE OF IGG4-RELATED DISEASE AFTER INDUCTION THERAPY: A RETROSPECTIVE STUDY2019

    • Author(s)
      Tomohiro Yoshida, Keisuke Nishimura, Kaoru Mizukawa, Keiichiro Kadoba, Hiroki Mukoyama, Daisuke Waki, Toshihiko Yokota, Hiroyuki Murabe
    • Organizer
      Annual European Congress of Rheumatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Presentation] IgG4関連疾患の顎下腺病変における超音波shear wave elastographyの有用性2018

    • Author(s)
      西村啓佑, 脇大輔, 門場啓一郎, 向山宙希, 横田敏彦
    • Organizer
      第46回 日本臨床免疫学会総会
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Presentation] The Efficacy of Denosumab for Prevention of Osteoporotic Fractures in Patients with Connective Tissue Diseases Receiving Very High Doses of Glucocorticoid2018

    • Author(s)
      keiichiro Kadoba, Keisuke Nishimura, Hiroki Mukoyama, Rintaro Saito, Daisuke Waki, Toshihiko Yokota
    • Organizer
      American College of Rheumatology 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Presentation] Shear Wave Elastography in the Evaluation of Submandibular Gland Characteristics in IgG4-Related Disease2018

    • Author(s)
      Keisuke Nishimura, Keiichiro kadoba, Hiroki Mukoyama, Rintaro Saito, Daisuke Waki, Toshihiko Yokota
    • Organizer
      American College of Rheumatology 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Presentation] ANCA関連血管炎に対する血漿交換療法の有用性2018

    • Author(s)
      西村啓佑、脇大輔、門場啓一郎、向山宙希、横田敏彦
    • Organizer
      第39回 日本アフェレシス学会
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Presentation] Inhibition of the mTOR Pathway and Glutaminolysis Facilitates the Expansion of Myeloid-Derived Suppressor Cells and Synergistically Ameliorates Arthritis in SKG Mice.2017

    • Author(s)
      Yo Ueda, Jun Saegusa, Takaichi Okano, Sho Sendo, Keisuke Nishimura, Hirotaka Yamada, Soshi Takahashi, Kengo Akashi, Akio Morinobu
    • Organizer
      第46回日本免疫学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Presentation] 3-bromopyruvate ameliorate autoimmune arthritis by modulating Th17/Treg cell differentiation and suppressing dendritic cell activation2017

    • Author(s)
      Takaichi Okano, jun Saegusa, Keisuke Nishimura, Yo Ueda, Sho Sendo, Soshi Takahashi, Miwa Nishida, Kengo Akashi, Akira Onishi, Akio Morinobu
    • Organizer
      第61回日本リウマチ学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Presentation] THE CLINICAL FEATURES OF 223 BEHCET'S DISEASE PATIENTS IN JAPAN2017

    • Author(s)
      R. Saito, K. Nishimura, H. Mukoyama, Y. Nakamura, T. Nagamoto, K. Akashi, A. Onishi, Y. Kogata, J. Saegusa, A. Morinobu, T. Yokota
    • Organizer
      EULAR Congress 2017 Annual European Congress of Rheumatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Presentation] SKGマウス肺病変の進展に伴って増加するCD11b+Gr1dim cellはGM-CSFによって誘導される2016

    • Author(s)
      千藤 荘, 仲 郁子, 津田 耕作, 岡野 隆一, 西田 美和, 明石 健吾, 高橋 宗史, 上田 洋, 西村 啓佑, 大西 輝, 古形 芳則, 三枝 淳, 森信 暁雄
    • Organizer
      第60回日本リウマチ学会・学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-04-21
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Presentation] 3-BROMOPYRUVATE AMELIORATES AUTOIMMUNE ARTHRITIS BY EXERTING A DUAL EFFECT ON BOTH TH17 AND TREG CELL DIFFERENTIATION AND DENDRITIC CELL ACTIVATION2016

    • Author(s)
      T. Okano, J. Saegusa, K. Nishimura, S. Takahashi, S. Sendo, Y. Ueda, A. Onishi, A. Morinobu.
    • Organizer
      EULAR Congress 2016 Annual European Congress of Rheumatology
    • Place of Presentation
      ロンドン(イギリス)
    • Year and Date
      2016-06-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Presentation] KNOCKOUT OF ENDOTHELIN TYPE B RECEPTOR SIGNALING ATTENUATES BLEOMYCIN-INDUCED SKIN SCLEROSIS IN MICE2016

    • Author(s)
      K. Akashi, J. Saegusa, S. Sendo, K. Nishimura, K. Tsuda, I. Naka, T. Okano, S. Takahashi, M. Nishida, Y. Ueda, A. Morinobu
    • Organizer
      EULAR Congress 2016 Annual European Congress of Rheumatology
    • Place of Presentation
      ロンドン(イギリス)
    • Year and Date
      2016-06-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Presentation] Dual Effect of 3-Bromopyruvate on Both Th17 and Treg Cell Differentiation and Dendritic Cell Activation Ameliorates Autoimmune Arthritis in Mice2016

    • Author(s)
      OKANO Takaichi, SAEGUSA Jun, NISHIMURA Keisuke, UEDA Yo, SENDO Sho, TAKAHASHI Soshi, MORINOBU Akio
    • Organizer
      第45回日本免疫学会総会・学術集会
    • Place of Presentation
      沖縄コンベンションセンター、ラグナガーデンホテル(沖縄県宜野湾市)
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-16K19599
  • [Presentation] Glutaminase1 inhibitor inhibits synoviocytes proliferation and ameliorates inflammatory arthritis in mice2016

    • Author(s)
      Soshi Takahashi, Jun Saegusa, Ikuko Naka, Kosaku Tsuda, Takaichi Okano, Kengo Akashi, Miwa Nishida, Keisuke Nishimura, Sho Sendo, Yo Ueda, Akira Onishi, Yoshinori Kogata, Akio Morinobu*
    • Organizer
      第60回日本リウマチ学会・学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-04-21
    • Data Source
      KAKENHI-PROJECT-16K19599
  • 1.  蔭山 豪一 (80631621)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  森信 暁雄 (10294216)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 3.  三枝 淳 (20514970)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 4.  籏智 さおり (70414117)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  脇 大輔 (00914243)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  大西 輝 (60634269)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  後藤 育子 (20757348)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  重岡 学 (20778716)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  木本 明 (30597167)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  明石 昌也 (40597168)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  明石 健吾 (60792637)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  筧 康正 (70772896)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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