Takahashi Keita 高橋慶太

… Alternative Names

TAKAHASHI KEITA 高橋慶太

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Researcher Number	20773740
Other IDs
Affiliation (Current)	2025: 横浜市立大学, 附属病院, 講師
Affiliation (based on the past Project Information) *help	2024: 横浜市立大学, 附属病院, 講師 2017 – 2022: 横浜市立大学, 附属病院, 助教 2016: 横浜市立大学, 附属病院, 指導診療医
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related / Basic Section 51030:Pathophysiologic neuroscience-related / Neurology Except Principal Investigator Basic Section 52020:Neurology-related
Keywords	Principal Investigator Nogo受容体 / Nogo / LOTUS / 多発性硬化症 / 軸索変性 / バイオマーカー / 筋萎縮性側索硬化症 / neuroinflammation / microglia / multiple sclerosis … More / マイクログリア / 神経炎症 / 血液バイオマーカー / 神経再生 / 神経免疫 / EAE / 炎症 / 神経変性 … More Except Principal Investigator LOTUS / ALS / 遺伝子治療 / PIR-B / Nogo Less

Development of Gene Therapy Targeting LOTUS for ALS
- Principal Investigator
  
  田中章景
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Yokohama City University
Development of a novel biomarker for ALS based on LOTUS, the functional molecule for neural regenerationPrincipal Investigator
- Principal Investigator
  
  高橋慶太
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Yokohama City University
Development of innovative treatment for multiple sclerosis based on control of neurodegeneration and inflammation by applying function of LOTUSPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Keita
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Yokohama City University
Development of ALS therapy targeting LOTUS, a functional molecule for neuronal regeneration
- Principal Investigator
  
  TANAKA Fumiaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Yokohama City University
development of biomarker for disease activity of multiple sclerosisPrincipal Investigator
- Principal Investigator
  
  Takahashi Keita
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Yokohama City University
Elucidation of pathogenesis and development of new therapy for neurological disorder in multiple sclerosisPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI KEITA
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Yokohama City University

All 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Ablation of interleukin-19 improves motor function in a mouse model of amyotrophic lateral sclerosis2021
- Author(s)
  Komiya Hiroyasu、Takeuchi Hideyuki、Ogawa Yuki、Suzuki Kosuke、Ogasawara Akihiro、Takahashi Keita、Azuma Yasu-Taka、Doi Hiroshi、Tanaka Fumiaki
- Journal Title
  
  Molecular Brain
  
  Volume: 14 Issue: 1 Pages: 74-74
- DOI
  10.1186/s13041-021-00785-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07531, KAKENHI-PROJECT-18K07532, KAKENHI-PROJECT-21K07298, KAKENHI-PROJECT-21K07465
[Journal Article] CCR2 is localized in microglia and neurons, as well as infiltrating monocytes, in the lumbar spinal cord of ALS mice.2020
- Author(s)
  Komiya H, Takeuchi H (責任著者), Ogawa Y, Hatooka Y, Takahashi K, Katsumoto A, Kubota S, Nakamura H, Kunii M, Tada M, Doi H, Tanaka F
- Journal Title
  
  Molecular Brain
  
  Volume: 13 Issue: 1 Pages: 64-64
- DOI
  10.1186/s13041-020-00607-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07531, KAKENHI-PROJECT-19K17014, KAKENHI-PROJECT-18K07503, KAKENHI-PROJECT-18K07532
[Journal Article] LOTUS as a novel biomarker of multiple sclerosis2019
- Author(s)
  Takahashi Keita、Tanaka Fumiaki
- Journal Title
  
  Clinical and Experimental Neuroimmunology
  
  Volume: 10 Issue: 1 Pages: 27-32
- DOI
  10.1111/cen3.12493
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15458
[Journal Article] Cerebrospinal fluid level of Nogo receptor 1 antagonist lateral olfactory tract usher substance (LOTUS) correlates inversely with the extent of neuroinflammation2018
- Author(s)
  Takahashi Keita、Takeuchi Hideyuki、Kurihara Yuji、Doi Hiroshi、Kunii Misako、Tanaka Kenichi、Nakamura Haruko、Fukai Ryoko、Tomita-Katsumoto Atsuko、Tada Mikiko、Higashiyama Yuichi、Joki Hideto、Koyano Shigeru、Takei Kohtaro、Tanaka Fumiaki
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 15 Issue: 1 Pages: 46-46
- DOI
  10.1186/s12974-018-1084-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16128, KAKENHI-PROJECT-16K19518, KAKENHI-PROJECT-16K21268, KAKENHI-PROJECT-18K07503, KAKENHI-PROJECT-18K15458
[Journal Article] Two cases of anaphylactic shock by methylprednisolone in neuromyelitis optica2018
- Author(s)
  Takahashi Keita、Asano Tetsuya、Higashiyama Yuichi、Koyano Shigeru、Doi Hiroshi、Takeuchi Hideyuki、Tanaka Fumiaki
- Journal Title
  
  Multiple Sclerosis Journal
  
  Volume: 24 Issue: 11 Pages: 1514-1516
- DOI
  10.1177/1352458518763099
- NAID
  120006808928
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07503, KAKENHI-PROJECT-18K15458
[Journal Article] Axonal Regeneration-related Molecules as Biomarkers for Multiple Sclerosis2016
- Author(s)
  高橋慶太, 竹内英之, 竹居光太郎, 田中章景.
- Journal Title
  
  BRAIN and NERVE
  
  Volume: 68 Issue: 1 Pages: 82-89
- DOI
  10.11477/mf.1416200351
- ISSN
  1344-8129, 1881-6096
- Year and Date
  2016-01-01
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15458
[Presentation] A novel automated quantitative system for LOTUS, a candidate biomarker for disease activity in MS2022
- Author(s)
  高橋慶太、竹内英之、国井美紗子、池田拓也、橋口俊太、田中健一、勝元敦子、多田美紀子、土井宏、田中章景
- Organizer
  第63回日本神経学会学術大会,
- Data Source
  KAKENHI-PROJECT-20K07761
[Presentation] An Endogenous Nogo receptor antagonist LOTUS, a novel therapeutic target for ALS2021
- Author(s)
  Takuya Ikeda, Keita Takahashi, Hiroshi Doi, Kohtaro Takei, Hideyuki Takeuchi, Fumiaki Tanaka
- Organizer
  Pan-Asia Consortium for Treatment and Research in ALS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07761
[Presentation] Evaluation of serum LOTUS as a biomarker of neuroinflammation2020
- Author(s)
  Keita Takahashi, Hideyuki Takeuchi, Misako Kunii, Ken-ichi Tanaka, Mikiko Tada, Kohtaro Takei, Fumiaki Tanaka
- Organizer
  日本神経学会
- Data Source
  KAKENHI-PROJECT-20K07761
[Presentation] フマル酸ジメチルへの薬剤変更後に抗MOG抗体陽性が顕在化した視神経脊髄炎関連疾患の3症例2019
- Author(s)
  高橋慶太、中村治子、三宅綾子、髙橋利幸、土井宏、竹内英之、田中章景
- Organizer
  第37回日本神経治療学会総会
- Data Source
  KAKENHI-PROJECT-18K15458
[Presentation] Anti-myelin oligodendrocyte glycoprotein antibody;positive neuromyelitis optica spectrum disorder manifested by switching to dimethyl fumarate.2019
- Author(s)
  Keita Takahashi, Haruko Nakamura, Ryoko Miyake, Toshiyuki Takahashi, Hiroshi Doi, Hideyuki Takeuchi, Fumiaki Tanaka
- Organizer
  第31回日本神経免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K15458
[Presentation] Cerebrospinal fluid level of LOTUS correlates inversely with the extent of neuroinflammation.2018
- Author(s)
  Keita Takahashi, Hideyuki Takeuchi, Yuji Kurihara, Hiroshi Doi, Misako Kunii, Ken-ichi Tanaka, Mikiko Tada, Shigeru Koyano, Kohtaro Takei, Fumiaki Tanaka.
- Organizer
  第59回日本神経学会総会
- Data Source
  KAKENHI-PROJECT-18K15458
[Presentation] 神経機能分子LOTUSはNogo receptor-1非依存的に実験的自己免疫性脳炎を増悪させる2017
- Author(s)
  高橋慶太、栗原裕司、竹内英之、竹居光太郎、田中章景
- Organizer
  第29回日本神経免疫学会学術大会
- Data Source
  KAKENHI-PROJECT-16K19518
[Presentation] 神経機能分子LOTUSの髄液中濃度は中枢神経感染症の炎症病勢と逆相関する2017
- Author(s)
  高橋慶太、竹内英之、栗原裕司、國井美沙子、田中健一、多田美紀子、竹居光太郎、田中章景
- Organizer
  第22回日本神経感染症学会総会
- Data Source
  KAKENHI-PROJECT-16K19518
[Presentation] LOTUS protein, an endogenous Nogo receptor antagonist, is involved in inflammation of experimental autoimmune encephalomyelitis2017
- Author(s)
  Keita Takahashi, Hideyuki Takeuchi, Yuji Kurihara, Hiroshi Doi, Misako Kunii, Ken-ichi Tanaka, Mikiko Tada, Shigeru Koyano, Kohtaro Takei, Fumiaki Tanaka.
- Organizer
  The XXIII World Congress of Neurology Conference, Kyoto.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19518
[Presentation] LOTUS protein, an endogenous Nogo receptor antagonist, is involved in induction of experimental autoimmune encephalomyelitis2016
- Author(s)
  Takahashi. K, Kurihara Y, Tanaka F, Takei K,
- Organizer
  第39回日本神経科学会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-16K19518
[Presentation] LOTUS protein, an endogenous Nogo receptor antagonist, is associated with induction of experimental autoimmune encephalomyelitis2016
- Author(s)
  高橋慶太、栗原裕司、竹内英之、竹居光太郎、田中章景
- Organizer
  第3回MSサマーカレッジ
- Place of Presentation
  神戸ポートピアホテル（兵庫）
- Year and Date
  2016-08-06
- Data Source
  KAKENHI-PROJECT-16K19518
[Presentation] 内在性Nogo受容体アンタゴニストLOTUSは実験的自己免疫性脳炎の病態に関与する2016
- Author(s)
  高橋慶太、栗原裕司、田中章景、竹居光太郎
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学会合同年会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-16K19518
[Presentation] 神経機能分子LOTUSは実験的自己免疫性脳炎の免疫病態にも関与する2016
- Author(s)
  高橋慶太、栗原裕司、竹内英之、竹居光太郎、田中章景
- Organizer
  第28回日本神経免疫学会学術大会
- Place of Presentation
  長崎ブリックホール（長崎）
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-16K19518

1. TANAKA Fumiaki (30378012)

# of Collaborated Projects: 5 results

# of Collaborated Products: 14 results
2. 土井宏 (10326035)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
3. 竹内英之 (30362213)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. TAKEI Kohtaro

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. 國井美紗子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takahashi Keita 高橋 慶太

TAKAHASHI KEITA 高橋 慶太

Research Projects

Research Products

Co-Researchers

Development of Gene Therapy Targeting LOTUS for ALS

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel biomarker for ALS based on LOTUS, the functional molecule for neural regenerationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of innovative treatment for multiple sclerosis based on control of neurodegeneration and inflammation by applying function of LOTUSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of ALS therapy targeting LOTUS, a functional molecule for neuronal regeneration

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

development of biomarker for disease activity of multiple sclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of pathogenesis and development of new therapy for neurological disorder in multiple sclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Ablation of interleukin-19 improves motor function in a mouse model of amyotrophic lateral sclerosis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CCR2 is localized in microglia and neurons, as well as infiltrating monocytes, in the lumbar spinal cord of ALS mice.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] LOTUS as a novel biomarker of multiple sclerosis2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cerebrospinal fluid level of Nogo receptor 1 antagonist lateral olfactory tract usher substance (LOTUS) correlates inversely with the extent of neuroinflammation2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Two cases of anaphylactic shock by methylprednisolone in neuromyelitis optica2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Axonal Regeneration-related Molecules as Biomarkers for Multiple Sclerosis2016

Author(s)

Journal Title

DOI

ISSN

Year and Date

Data Source

[Presentation] A novel automated quantitative system for LOTUS, a candidate biomarker for disease activity in MS2022

Author(s)

Organizer

Data Source

[Presentation] An Endogenous Nogo receptor antagonist LOTUS, a novel therapeutic target for ALS2021

Author(s)

Takahashi Keita 高橋慶太

TAKAHASHI KEITA 高橋慶太