SASAKI Mika 佐々木美佳

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SASAKI MIKA 佐々木美佳

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Researcher Number	20774061
Other IDs
Affiliation (Current)	2022: 岐阜大学, 大学院医学系研究科, 研究員
Affiliation (based on the past Project Information) *help	2018 – 2022: 新潟大学, 医歯学系, 助教 2016 – 2017: 新潟大学, 医歯学総合病院, 技術補佐員
Review Section/Research Field	Principal Investigator Basic Section 55050:Anesthesiology-related / Anesthesiology Except Principal Investigator Basic Section 55050:Anesthesiology-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Keywords	Principal Investigator セロトニン / アストロサイト / モルヒネ / 脊髄後角 / オピオイド誘発性痒み / セロトニン受容体 / オンダンセトロン / ガストリン放出ペプチド / MAPキナーゼ / GRP … More / 高用量モルヒネ / 髄腔内投与 / MAP kinase / 薬理学 / オピオイド誘発性痛覚過敏 / 術後痛モデル / 術後遷延痛 / 機械刺激 / 熱刺激 / 術後痛 / オスモティックポンプ / オピオイド / 興奮性シナプス伝達 … More Except Principal Investigator 青斑核 / 薬理遺伝学的手法 / 全身麻酔薬 / in vivoパッチクランプ / 化学遺伝学的手法 / 慢性痛 / 脊髄後角 / 可塑性変化 / in vivo patch clamp / 脊髄可塑性 / 神経障害性疼痛 / 脊髄－脳連関 / フラビン蛋白蛍光イメージング法 / in vivoパッチクランプ法 / グリア活性化 / セロトニン / 脊髄ー脳連関 / in vivo脊髄パッチクランプ法 / フラビンタンパク蛍光イメージング / 生理学的解析 / グリア細胞活性化機構 / 脊髄-脳連関 / 脊髄―脳連関 / 脊髄細胞外記録 / 脊髄―能連関 / フラビン蛋白蛍光イメージング / 麻酔薬 / chemogenetics / 薬理遺伝学 / 電気生理 / DREADD / 慢性疼痛 / 下降性疼痛抑制系 / 化学遺伝学 / フラビンタンパク蛍光イメージング方 / in vivo電気生理学 / 光遺伝学 / パッチクランプ / 光遺伝学的手法 Less

Manipulating Descending Pain Suppression Systems Using Chemogenetics to Find Seeds for Chronic Pain Treatment
- Principal Investigator
  
  紙谷義孝
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Niigata University
光遺伝学を利用した青斑核ニューロン制御による全身麻酔薬作用機序の解明
- Principal Investigator
  
  倉部美起
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Niigata University
Does opioid analgesia cause prolonged postoperative pain? -Involvement of spinal astroglial activation-Principal Investigator
- Principal Investigator
  
  佐々木美佳
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Niigata University
Elucidating mechanisms of action of general anesthetics using chemogenetics
- Principal Investigator
  
  Kamiya Yoshinori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Niigata University
Brain-Spinal Cord Plasticity Changes during the Establishment of Chronic Pain: Elucidation of the Role of Inhibitory Neural Circuits
- Principal Investigator
  
  Miyuki Kurabe
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Niigata University
Studies on effects of serotonin in neuron-glia interaction for opioid-induced hyperalgesia.Principal Investigator
- Principal Investigator
  
  SASAKI MIKA
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Niigata University
Physiological analysis of spinal cord-brain coupling in neuropathic pain and elucidation of glial cell activation mechanism.
- Principal Investigator
  
  Kamiya Yoshinori
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Niigata University
Elucidation of intracellular signal of opioid-induced itching and TRPA1-itch signal interactionPrincipal Investigator
- Principal Investigator
  
  SASAKI MIKA
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Anesthesiology
- Research Institution
  Niigata University

All 2021 2019 2017 2016

All Journal Article Presentation

[Journal Article] Subanesthetic Dose of Propofol Activates the Reward System in Rats2021
- Author(s)
  Nagata Isao、Sasaki Mika、Miyazaki Tomoyuki、Saeki Kensuke、Ogawa Ken-ichi、Kamiya Yoshinori
- Journal Title
  
  Anesthesia & Analgesia
  
  Volume: Publish Ahead of Print
- DOI
  10.1213/ane.0000000000005847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22652, KAKENHI-PROJECT-20K09215
[Journal Article] Serotonin Plays a Key Role in the Development of Opioid-Induced Hyperalgesia in Mice2021
- Author(s)
  Sasaki Mika、Kamiya Yoshinori、Bamba Keiko、Onishi Takeshi、Matsuda Keiichiro、Kohno Tatsuro、Kurabe Miyuki、Furutani Kenta、Yanagimura Harue
- Journal Title
  
  The Journal of Pain
  
  Volume: - Pages: 715-729
- DOI
  10.1016/j.jpain.2020.12.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09215, KAKENHI-PROJECT-18H02897, KAKENHI-PROJECT-18K08811, KAKENHI-PROJECT-19K22652, KAKENHI-PROJECT-21K08943
[Journal Article] Neurosteroid dehydroepiandrosterone sulphate enhances pain transmission in rat spinal cord dorsal horn2019
- Author(s)
  Yamamoto Goh、Kamiya Yoshinori、Sasaki Mika、Ikoma Miho、Baba Hiroshi、Kohno Tatsuro
- Journal Title
  
  British journal of anaesthesia
  
  Volume: 印刷中
- DOI
  10.1016/j.bja.2019.03.026
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02897, KAKENHI-PROJECT-19K22652, KAKENHI-PROJECT-17K11104, KAKENHI-PROJECT-18K16475
[Journal Article] Acute spatial spread of NO‐mediated potentiation during hindpaw ischaemia in mice2019
- Author(s)
  Onishi T, Watanabe T, Sasaki M, Kamiya Y, Horie M, Tsukano H, Hishida R, Kohno T, Takebayashi H, Baba H, Shibuki K
- Journal Title
  
  J Physiol
  
  Volume: 597 Pages: 3441-3455
- DOI
  10.1113/jp277615
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06518, KAKENHI-PROJECT-19K22652, KAKENHI-PROJECT-16H01892, KAKENHI-PROJECT-18H02897, KAKENHI-PROJECT-17K11104, KAKENHI-PROJECT-18K16475
[Presentation] Opioid-induced hyperalgesia induced by chronic administration of morphine is caused by serotonin in spinal dorsal horn and, in part, through the 5-HT3 receptor.2019
- Author(s)
  Mika Sasaki, Yoshinori Kamiya, Keiko Bamba, Moegi Tanaka, Takeshi Ohnishi
- Organizer
  Neuroscience 2019
- Data Source
  KAKENHI-PROJECT-19K22652
[Presentation] Opioid-induced hyperalgesia induced by chronic administration of morphine is caused by serotonin in spinal dorsal horn and, in part, through the 5-HT3 receptor.2019
- Author(s)
  Mika Sasaki, Yoshinori Kamiya, Keiko Bamba, Moegi Tanaka, Takeshi Ohnishi
- Organizer
  Neuroscience 2019
- Data Source
  KAKENHI-PROJECT-18H02897
[Presentation] モルヒネ慢性投与による痛覚過敏は脊髄後角のセロトニンによって生じ、一部5HT-3受容体を介する2019
- Author(s)
  紙谷義孝, 佐々木美佳, 田中萌生, 番場景子
- Organizer
  第66回日本麻酔科学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02897
[Presentation] "Changes in spinal dorsal horn neuron characteristics from the early stage of peripheral nerve injury to chronic pain transition2019
- Author(s)
  Miyuki Kurabe, Mika Sasaki, Hiroshi Baba
- Organizer
  Neuroscience 2019
- Data Source
  KAKENHI-PROJECT-18K08811
[Presentation] Opioid-induced hyperalgesia by chronic administration of morphine is caused by serotonin in spinal dorsal horn and, in part, through the 5-HT3 receptor.2019
- Author(s)
  Mika Sasaki., Yoshinori Kamiya., Keiko Bamba., Moegi Tanaka. and Takeshi Ohnishi.
- Organizer
  Society for Neuroscience 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16475
[Presentation] Contribution of Itch in Pain-related Behavior by Intrathecal Administration of Morphine, and Ondansetron, The 5HT3 Antagonist, Suppressed Pain-like Behavior2017
- Author(s)
  Yoshinori Kamiya, Mika Sasaki, Tatsuro Kohno
- Organizer
  American Society of Anesthesiologists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20084
[Presentation] 高用量モルヒネ脊髄腔内投与による痛み関連行動メカニズムの解明2016
- Author(s)
  佐々木美佳　河野達郎　紙谷義孝
- Organizer
  第63回日本麻酔科学会
- Place of Presentation
  マリンメッセ福岡 (福岡県福岡市)
- Year and Date
  2016-05-26
- Data Source
  KAKENHI-PROJECT-16K20084

1. Miyuki Kurabe (30635579)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
2. Kamiya Yoshinori (90381491)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
3. 上野将紀 (40435631)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 大西毅 (60804573)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. 渡部達範 (30748330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 馬場洋 (00262436)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 菱田竜一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 渋木克栄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SASAKI Mika 佐々木 美佳

SASAKI MIKA 佐々木 美佳

Research Projects

Research Products

Co-Researchers

Manipulating Descending Pain Suppression Systems Using Chemogenetics to Find Seeds for Chronic Pain Treatment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

光遺伝学を利用した青斑核ニューロン制御による全身麻酔薬作用機序の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Does opioid analgesia cause prolonged postoperative pain? -Involvement of spinal astroglial activation-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating mechanisms of action of general anesthetics using chemogenetics

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Brain-Spinal Cord Plasticity Changes during the Establishment of Chronic Pain: Elucidation of the Role of Inhibitory Neural Circuits

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies on effects of serotonin in neuron-glia interaction for opioid-induced hyperalgesia.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Physiological analysis of spinal cord-brain coupling in neuropathic pain and elucidation of glial cell activation mechanism.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of intracellular signal of opioid-induced itching and TRPA1-itch signal interactionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Subanesthetic Dose of Propofol Activates the Reward System in Rats2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serotonin Plays a Key Role in the Development of Opioid-Induced Hyperalgesia in Mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neurosteroid dehydroepiandrosterone sulphate enhances pain transmission in rat spinal cord dorsal horn2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acute spatial spread of NO‐mediated potentiation during hindpaw ischaemia in mice2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] Opioid-induced hyperalgesia induced by chronic administration of morphine is caused by serotonin in spinal dorsal horn and, in part, through the 5-HT3 receptor.2019

Author(s)

Organizer

Data Source

[Presentation] Opioid-induced hyperalgesia induced by chronic administration of morphine is caused by serotonin in spinal dorsal horn and, in part, through the 5-HT3 receptor.2019

Author(s)

Organizer

SASAKI Mika 佐々木美佳

SASAKI MIKA 佐々木美佳