• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Kaji Noriyuki  梶 典幸

Researcher Number 20779318
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-7423-5679
Affiliation (Current) 2025: 麻布大学, 獣医学部, 講師
Affiliation (based on the past Project Information) *help 2021 – 2024: 麻布大学, 獣医学部, 講師
2019 – 2021: 麻布大学, 獣医学部, 助教
2016 – 2018: 東京大学, 大学院農学生命科学研究科(農学部), 助教
Review Section/Research Field
Principal Investigator
Basic Section 42030:Animal life science-related / Veterinary medical science
Except Principal Investigator
Basic Section 52010:General internal medicine-related
Keywords
Principal Investigator
消化管 / 消化管運動 / カハール介在細胞 / 炎症 / 一酸化窒素 / 神経 / マクロファージ / オンコスタチンM / セロトニン / カハール間質細胞 … More / 腸内細菌 / 腸管神経 / 老化 / 間葉系細胞 / 組織修復・再生 / 腸炎 / 可塑性 / ICC … More
Except Principal Investigator
過敏性 / 位置合わせ / 深層学習 / パターン分類 / 消化管運動 / トリプトファン代謝産物 / 炎症 / 脳腸相関 / トリプトファン / 細胞内Ca / 微小電極アレイ / 内在神経 / 平滑筋 / ペースメーカ / 炎症性腸疾患 / 過敏性腸症候群 / 消化管 Less
  • Research Projects

    (6 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (8 People)
  •  Function of Oncostatin M in the process of homeostasis and its disruption in the gastrointestinal musculature.Principal Investigator

    • Principal Investigator
      梶 典幸
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42030:Animal life science-related
    • Research Institution
      Azabu University
  •  Evaluation of excitation coordination disorder underlying gut hypersensitivity in functional micro-image

    • Principal Investigator
      中山 晋介
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Nagoya University
  •  Crosstalk between interstitial cells of Cajal and gut microbiotaPrincipal Investigator

    • Principal Investigator
      梶 典幸
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 42030:Animal life science-related
    • Research Institution
      Azabu University
  •  Visualization of micro-coordination in the GI tract reflecting irritability and inflammatory reactions: Elucidation of pathological conditions and development of treatment strategy

    • Principal Investigator
      Nakayama Shinsuke
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Nagoya University
  •  Survival and death signaling in interstitial pacemaker cells induced by nitric oxidePrincipal Investigator

    • Principal Investigator
      KAJI NORIYUKI
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 42030:Animal life science-related
    • Research Institution
      Azabu University
      The University of Tokyo
  •  Analysis of plasticity of interstitial cells of Cajal and its molecular mechanism by cell fate tracing methodPrincipal Investigator

    • Principal Investigator
      Kaji Noriyuki
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Veterinary medical science
    • Research Institution
      The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

  • [Journal Article] Investigation of periodontal disease development and Porphyromonas gulae FimA genotype distribution in small dogs2024

    • Author(s)
      Yasuda Junya、Yasuda Hidemi、Nomura Ryota、Matayoshi Saaya、Inaba Hiroaki、Gongora Enrique、Iwashita Naoki、Shirahata So、Kaji Noriyuki、Akitomo Tatsuya、Mitsuhata Chieko、Uchiyama Jumpei、Fukuyama Tomoki、Matsumoto-Nakano Michiyo、Nakano Kazuhiko、Murakami Masaru
    • Journal Title

      Scientific Reports

      Volume: 14 Issue: 1 Pages: 5360-5360

    • DOI

      10.1038/s41598-024-55842-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15001, KAKENHI-PROJECT-22K08580
  • [Journal Article] Fuzapladib reduces postsurgical inflammation in the intestinal muscularis externa2023

    • Author(s)
      KAJI Noriyuki、IWAOKA Kosuzu、NAKAMURA Shinichiro、TSUKAMOTO Atsushi
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 85 Issue: 11 Pages: 1151-1156

    • DOI

      10.1292/jvms.23-0257

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K15001
  • [Journal Article] Toceranib phosphate (Palladia) reverses type 1 diabetes by preserving islet function in mice2023

    • Author(s)
      KISHI Kazuhisa、YONEZAWA Tomohiro、KAJI Noriyuki、GOTO Momo、NONOSHITA Yuma、IIO Aki、TSURU Yoshiharu、HORI Masatoshi
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 85 Issue: 7 Pages: 781-789

    • DOI

      10.1292/jvms.23-0154

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K15001
  • [Journal Article] Interstitial cells of Cajal in gastrointestinal inflammatory diseases2023

    • Author(s)
      Kaji N, Hori M
    • Journal Title

      Journal of Smooth Muscle Research

      Volume: 59 Issue: 0 Pages: 1-13

    • DOI

      10.1540/jsmr.59.1

    • ISSN
      0916-8737, 1884-8796
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03125, KAKENHI-PROJECT-21K15001
  • [Journal Article] Transcriptome analysis of mesenchymal stromal cells of the large and small intestinal smooth muscle layers reveals a unique gastrointestinal stromal signature2023

    • Author(s)
      Chaen Takashi、Kurosawa Tamaki、Kishi Kazuhisa、Kaji Noriyuki、Ikemoto-Uezumi Madoka、Uezumi Akiyoshi、Hori Masatoshi
    • Journal Title

      Biochemistry and Biophysics Reports

      Volume: 34 Pages: 101478-101478

    • DOI

      10.1016/j.bbrep.2023.101478

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K15001, KAKENHI-PROJECT-22K11845
  • [Journal Article] Dental pulp stem cells as a therapy for congenital entero-neuropathy.2022

    • Author(s)
      Yoshimaru, K., Yamaza, Y., Kajioka, S., Sonoda, S., Yanagi, Y., Matsuura, T., Yoshizumi, J., Oda, Y., Iwata, N., Takai, C., Nakayama, S., Taguchi, T.
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1

    • DOI

      10.1038/s41598-022-10077-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19584, KAKENHI-PROJECT-19H03558, KAKENHI-PROJECT-23K21447
  • [Journal Article] Classification of Pacemaker Dynamics in the Mouse Intestine by Field Potential Microimaging2022

    • Author(s)
      Iwata, N., Takai, C., Mochizuki, N., Yamauchi, M., Kaji, N., Kasahara, Y., Nakayama, S.
    • Journal Title

      Biosensors and Bioelectronics X:

      Volume: 10 Pages: 1001111-1001111

    • DOI

      10.1016/j.biosx.2022.100111

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03558, KAKENHI-PROJECT-22K19584
  • [Journal Article] Npr2 mutant mice show vasodilation and undeveloped adipocytes in mesentery2021

    • Author(s)
      Sogawa-Fujiwara Chizuru、Fujiwara Yasuhiro、Hanagata Atsuki、Yang Qunhui、Mihara Taiki、Kaji Noriyuki、Kunieda Tetsuo、Hori Masatoshi
    • Journal Title

      BMC Research Notes

      Volume: 14 Issue: 1

    • DOI

      10.1186/s13104-021-05853-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K14604, KAKENHI-PROJECT-20K15678
  • [Journal Article] Development of a quantitative method for evaluating small intestinal motility using ultrasonography in mice2019

    • Author(s)
      Kishi Kazuhisa、Kaji Noriyuki、Endo Mari、Tsuru Yoshiharu、Oikawa Tetsuro、Hori Masatoshi
    • Journal Title

      Exp. Anim.

      Volume: 68 Issue: 3 Pages: 381-389

    • DOI

      10.1538/expanim.19-0030

    • NAID

      130007689886

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K14604
  • [Journal Article] Neural anti-inflammatory action mediated by two types of acetylcholine receptors in the small intestine2019

    • Author(s)
      Kimura Hitomi、Imura Yu-ki、Tomiyasu Hirotaka、Mihara Taiki、Kaji Noriyuki、Ohno Koichi、Unno Toshihiro、Tanahashi Yasuyuki、Jan Tong-Rong、Tsubone Hirokazu、Ozaki Hiroshi、Hori Masatoshi
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 5887-5887

    • DOI

      10.1038/s41598-019-41698-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K14604, KAKENHI-PROJECT-17H05043
  • [Journal Article] Hyperglycemia in the early stages of type 1 diabetes accelerates gastric emptying through increased networks of interstitial cells of Cajal2019

    • Author(s)
      Kishi Kazuhisa、Kaji Noriyuki、Kurosawa Tamaki、Aikiyo Satoshi、Hori Masatoshi
    • Journal Title

      PLOS ONE

      Volume: 14 Issue: 10 Pages: e0222961-e0222961

    • DOI

      10.1371/journal.pone.0222961

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K14604
  • [Journal Article] Serotonin 3 receptor signaling regulates 5-fluorouracil mediated apoptosis indirectly via TNF-α production by enhancing serotonin release from enterochromaffin cells2019

    • Author(s)
      Mikawa Shoma、Kondo Makoto、Kaji Noriyuki、Mihara Taiki、Yoshitake Ryohei、Nakagawa Takayuki、Takamoto Masaya、Nishimura Ryohei、Shimada Shoichi、Ozaki Hiroshi、Hori Masatoshi
    • Journal Title

      The FASEB Journal

      Volume: 33 Issue: 2 Pages: 1669-1680

    • DOI

      10.1096/fj.201701200rr

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K14604, KAKENHI-PROJECT-19K11440
  • [Journal Article] Disruption of the pacemaker activity of interstitial cells of Cajal via nitric oxide contributes to postoperative ileus2018

    • Author(s)
      Kaji N, Nakayama S, Horiguchi K, Iino S, Ozaki H, Hori M
    • Journal Title

      Neurogastroenterol Motil

      Volume: 15 Issue: 8

    • DOI

      10.1111/nmo.13334

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221205, KAKENHI-PROJECT-16H06740, KAKENHI-PROJECT-16K15058, KAKENHI-PROJECT-18K14604
  • [Journal Article] Induction of myosin light chain kinase and CPI-17 by TGF-β accelerates contractile activity in intestinal epithelial cells2018

    • Author(s)
      ISLAM Md. Shafiqul、KAJI Noriyuki、MIKAWA Shoma、YANG Qunhui、KUSABE Moriaki、HORI Masatoshi、OZAKI Hiroshi
    • Journal Title

      Journal of Veterinary Medical Science

      Volume: 80 Issue: 6 Pages: 977-984

    • DOI

      10.1292/jvms.17-0684

    • NAID

      130007412706

    • ISSN
      0916-7250, 1347-7439
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K14604
  • [Journal Article] Micro-coordination of Pacemaker Potentials in the Intestine of the Mouse.2017

    • Author(s)
      Morishita H, Iwata N, Takai C, Mochizuki N, Kaji N, Hori M, Kajioka S, Nakayama S.
    • Journal Title

      Gastroenterology

      Volume: 5085(17) Issue: 8 Pages: 35483-35485

    • DOI

      10.1053/j.gastro.2017.04.016

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462445, KAKENHI-PROJECT-25221205, KAKENHI-PROJECT-16H06740, KAKENHI-PROJECT-16K15058
  • [Journal Article] The essential role of phospho-T38 CPI-17 in the maintenance of physiological blood pressure using genetically modified mice2017

    • Author(s)
      Yang Q, Fujii W, Kaji N, Kakuta S, Kada K, Kuwahara M, Tsubone H, Ozaki H, Hori M
    • Journal Title

      FASEB J

      Volume: 32(4) Issue: 4 Pages: 2095-2109

    • DOI

      10.1096/fj.201700794r

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25221205, KAKENHI-PROJECT-16H06740, KAKENHI-PROJECT-18K14604, KAKENHI-PROJECT-26712025
  • [Journal Article] Therapeutic Action of Honokiol on Postoperative Ileus via Downregulation of iNOS Gene Expression2017

    • Author(s)
      Mihara T, Mikawa S, Kaji N, Endo M, Oikawa T, Tong-Rong J, Ozaki H, Hori M. Inflammation
    • Journal Title

      Inflammation

      Volume: 40(4) Issue: 4 Pages: 1331-1341

    • DOI

      10.1007/s10753-017-0576-7

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221205, KAKENHI-PROJECT-16H06740, KAKENHI-PROJECT-16J05803, KAKENHI-PROJECT-16K15058
  • [Presentation] 腸内細菌によるカハール間質細胞の恒常性維持機構の解明2023

    • Author(s)
      林 茉由、梶 典幸
    • Organizer
      第97回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-21K15001
  • [Presentation] Multipotent dental pulp stem cells of deciduous teeth improve gastrointestinal function in a murine model of entero-neuropathy2023

    • Author(s)
      中山 晋介、岩田 尚子、高井 千穂、梶岡 俊一
    • Organizer
      日本生理学会(第100回、京都)
    • Data Source
      KAKENHI-PROJECT-19H03558
  • [Presentation] 神経節細胞僅少症マウス結腸の時間空間的電気活動研究2020

    • Author(s)
      中山晋介、吉丸耕一朗、山座孝義、梶岡俊一
    • Organizer
      第97回日本生理学会
    • Data Source
      KAKENHI-PROJECT-19H03558
  • [Presentation] Gastrin-releasing peptide modulates the pacemaker function of interstitial cells of Cajal2019

    • Author(s)
      梶 典幸、岸 和寿、黒澤 珠希、堀 正敏
    • Organizer
      第92回日本薬理学会年会(大阪国際会議場、大阪)
    • Data Source
      KAKENHI-PROJECT-18K14604
  • [Presentation] 炎症病態における消化管ペースメーカー細胞の機能破綻とその治療法の探索2019

    • Author(s)
      梶 典幸、中山 晋介、飯野 哲、堀口 和秀、堀 正敏
    • Organizer
      第140回日本薬理学会関東部会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K14604
  • [Presentation] ミオシンホスファターゼ阻害因子CPI-17欠損による消化管運動抑制2018

    • Author(s)
      梶典幸、槙郁風、尾崎博、堀正敏
    • Organizer
      第60回日本平滑筋学会総会(東京慈恵医科大学、東京)
    • Data Source
      KAKENHI-PROJECT-18K14604
  • [Presentation] 術後イレウスにおける消化管ペースメーカー細胞Interstitial cells of Cajalの病態変化2016

    • Author(s)
      梶 典幸、中山 晋介、堀口 和秀、飯野 哲、尾崎 博、堀 正敏
    • Organizer
      第18回日本神経消化器病学会(合同学術集会)
    • Place of Presentation
      北海道大学 医学部学友会館フラテ(北海道札幌市)
    • Year and Date
      2016-09-09
    • Data Source
      KAKENHI-PROJECT-16H06740
  • [Presentation] 術後イレウスにおける消化管ペースメーカー細胞Interstitial cells of Cajalの病態変化2016

    • Author(s)
      梶 典幸、中山 晋介、堀口 和秀、飯野 哲、尾崎 博、堀 正敏
    • Organizer
      第159回日本獣医学会学術集会
    • Place of Presentation
      日本大学 藤沢キャンパス(神奈川県藤沢市)
    • Year and Date
      2016-09-06
    • Data Source
      KAKENHI-PROJECT-16H06740
  • 1.  Nakayama Shinsuke (30192230)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 2.  鈴木 治彦 (90283431)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  本田 育美 (30273204)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  KAJIOKA Syunichi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 5.  HORIGUCHI Kazuhide
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  堀 正敏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 7.  尾崎 博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 8.  飯野 哲
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi