Sato Hiroki 佐藤拓輝

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Hiroki Sato 佐藤拓輝

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Researcher Number	20781173
Other IDs
Affiliation (Current)	2025: 横浜市立大学, 理学部, 講師
Affiliation (based on the past Project Information) *help	2024: 横浜市立大学, 理学部, 講師 2021 – 2022: 金沢大学, がん進展制御研究所, 特任助教 2020: 金沢大学, ナノ生命科学研究所, 特任助教 2016 – 2019: 金沢大学, がん進展制御研究所, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Respiratory surgery
Keywords	Principal Investigator MET / HGF / がん転移ニッチ / 環状ペプチド / 薬剤耐性 / イメージング / Met

転移微小環境形成過程における非標的臓器ホメオスタシス変化に関する研究Principal Investigator
- Principal Investigator
  
  佐藤拓輝
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Yokohama City University
細胞増殖因子プロセッシングのエンドクリン制御を起点とするがん転移ニッチ形成の研究Principal Investigator
- Principal Investigator
  
  佐藤拓輝
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kanazawa University
Development of a low-invasive diagnostic method for tumor characterization using macrocyclic peptidePrincipal Investigator
- Principal Investigator
  
  Sato Hiroki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kanazawa University
Studies of drug resistance and micro-metastasis using macrocyclic peptides as molecular imaging probesPrincipal Investigator
- Principal Investigator
  
  Hiroki Sato
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Respiratory surgery
- Research Institution
  Kanazawa University

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] MET kinase inhibitor reverses resistance to entrectinib induced by hepatocyte growth factor in tumors with NTRK1 or ROS1 rearrangements2023
- Author(s)
  Takumi Y, Arai S, Suzuki C, Fukuda K, Nishiyama A, Takeuchi S, Sato H, Matsumoto K, Sugio K, Yano S.
- Journal Title
  
  Cancer Medicine
  
  Volume: 12 Issue: 5 Pages: 5809-5820
- DOI
  10.1002/cam4.5342
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09168, KAKENHI-PROJECT-21K18250, KAKENHI-PROJECT-21K15482
[Journal Article] Two-Chain Mature Hepatocyte Growth Factor-Specific Positron Emission Tomography Imaging in Tumors Using 64Cu-Labeled HiP-8, a Nonstandard Macrocyclic Peptide Probe2023
- Author(s)
  Shota Warashina , Hiroki Sato, Maki Zouda, Maiko Takahashi, Yasuhiro Wada, Toby Passioura, Hiroaki Suga, Yasuyoshi Watanabe, Kunio Matsumoto, Hidefumi Mukai
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 20(4) Issue: 4 Pages: 2029-2038
- DOI
  10.1021/acs.molpharmaceut.2c01020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15482, KAKENHI-PROJECT-21K18250, KAKENHI-PROJECT-20H05618
[Journal Article] Designing receptor agonists with enhanced pharmacokinetics by grafting macrocyclic peptides into fragment crystallizable regions2022
- Author(s)
  Sakai Katsuya、Sugano-Nakamura Nozomi、Mihara Emiko、Rojas-Chaverra Nichole Marcela、Watanabe Sayako、Sato Hiroki、Imamura Ryu、Voon Dominic Chih-Cheng、Sakai Itsuki、Yamasaki Chihiro、Tateno Chise、Shibata Mikihiro、Suga Hiroaki、Takagi Junichi、Matsumoto Kunio
- Journal Title
  
  Nature Biomedical Engineering
  
  Volume: 7 Issue: 2 Pages: 164-176
- DOI
  10.1038/s41551-022-00955-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18250, KAKENHI-PROJECT-21K15482, KAKENHI-PROJECT-20H05618, KAKENHI-PROJECT-20H00455, KAKENHI-PROJECT-21H01771, KAKENHI-PROJECT-20K06553, KAKENHI-PUBLICLY-21H00247
[Journal Article] Dimer interface in natural variant NK1 is dispensable for HGF-dependent Met receptor activation.2021
- Author(s)
  Yumiko Tahira, Katsuya Sakai, Hiroki Sato, Ryu Imamura, and Kunio Matsumoto
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 22 Issue: 17 Pages: 9240-9240
- DOI
  10.3390/ijms22179240
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06553, KAKENHI-PROJECT-21K15482
[Journal Article] Cyclic Peptide-Based Biologics Regulating HGF-MET.2020
- Author(s)
  Hiroki Sato, Ryu Imamura, Hiroaki Suga, Kunio Matsumoto, Katsuya Sakai
- Journal Title
  
  International journal of molecular sciences
  
  Volume: 21 Issue: 21 Pages: 7977-7977
- DOI
  10.3390/ijms21217977
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06553, KAKENHI-PROJECT-19H03499, KAKENHI-PROJECT-18K15306
[Journal Article] Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach.2019
- Author(s)
  Jangphattananont N, Sato H, Imamura R, Sakai K, Terakado Y, Murakami K, Barker N, Oshima H, Oshima M, Takagi J, Kato Y, Yano S, Matsumoto K
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 12 Issue: 12 Pages: 2955-2955
- DOI
  10.3390/ijms20122955
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15306, KAKENHI-PROJECT-17H01399, KAKENHI-PROJECT-17H01420, KAKENHI-PROJECT-19H03498, KAKENHI-PROJECT-19H03499, KAKENHI-PROJECT-17K07161, KAKENHI-PROJECT-18K19298
[Journal Article] Impaired ligand-dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer.2019
- Author(s)
  Miao W, Sakai K, Sato H, Imamura R, Jangphattananont N, Takagi J, Nishita M, Minami Y, Matsumoto K
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 10 Pages: 3340-3349
- DOI
  10.1111/cas.14142
- NAID
  120006733132
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15306, KAKENHI-PROJECT-17H01420, KAKENHI-PROJECT-19H03499, KAKENHI-PROJECT-18K19298
[Journal Article] Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor.2019
- Author(s)
  Sakai K, Passioura T, Sato H, Ito K, Furuhashi H, Umitsu M, Takagi J, Kato Y, Mukai H, Warashina S, Zouda M, Watanabe Y, Yano S, Shibata M, Suga H, Matsumoto K
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 15 Issue: 6 Pages: 598-606
- DOI
  10.1038/s41589-019-0285-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15306, KAKENHI-PUBLICLY-19H05257, KAKENHI-PROJECT-17H01420, KAKENHI-PROJECT-18H01836, KAKENHI-PROJECT-19H03499, KAKENHI-PROJECT-18K19287, KAKENHI-PROJECT-18K19298
[Presentation] 転移ニッチ形成におけるHGF-METシグナルの活性化と環状ペプチド阻害2022
- Author(s)
  佐藤　拓輝
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K15482
[Presentation] HGF活性の遠隔制御によるがん転移ニッチ形成2022
- Author(s)
  佐藤　拓輝
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K15482
[Presentation] HGF conversion in bronchial epithelial cells triggers pre-metastatic niche formation in the lung2021
- Author(s)
  佐藤　拓輝
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K15482
[Presentation] 胃組織修復および発がん機構における活性型HGFの役割2020
- Author(s)
  佐藤　拓輝
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K15306
[Presentation] Specific Detection of Active HGF for Diagnosis Reflecting Activation Status of HGF-MET Signaling by Macrocyclic Peptide2019
- Author(s)
  佐藤拓輝
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K15306
[Presentation] HGFの局所的活性化を介した肺転移微小環境の形成2018
- Author(s)
  佐藤　拓輝
- Organizer
  第27回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-18K15306
[Presentation] HGFの局所的活性化に起因する転移性ニッチ形成機構2018
- Author(s)
  佐藤　拓輝
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K15306
[Presentation] PET imaging system reflecting activation status of HGF/Met signaling with macro-cyclic peptides2018
- Author(s)
  Hiroki Sato
- Organizer
  The 1st NanoLSI International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15306
[Presentation] Intrinsic HGF Induced by Cancer Cells Promotes Lung Metastasis in Met-high Expressing Melanomas2017
- Author(s)
  佐藤　拓輝
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H06830

1. MUKAI Hidefumi (60570885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. SAKAI Katsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 松本邦夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 杉尾賢二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sato Hiroki 佐藤 拓輝

Hiroki Sato 佐藤 拓輝

Research Projects

Research Products

Co-Researchers

転移微小環境形成過程における非標的臓器ホメオスタシス変化に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞増殖因子プロセッシングのエンドクリン制御を起点とするがん転移ニッチ形成の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a low-invasive diagnostic method for tumor characterization using macrocyclic peptidePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies of drug resistance and micro-metastasis using macrocyclic peptides as molecular imaging probesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] MET kinase inhibitor reverses resistance to entrectinib induced by hepatocyte growth factor in tumors with NTRK1 or ROS1 rearrangements2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Two-Chain Mature Hepatocyte Growth Factor-Specific Positron Emission Tomography Imaging in Tumors Using 64Cu-Labeled HiP-8, a Nonstandard Macrocyclic Peptide Probe2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Designing receptor agonists with enhanced pharmacokinetics by grafting macrocyclic peptides into fragment crystallizable regions2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dimer interface in natural variant NK1 is dispensable for HGF-dependent Met receptor activation.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cyclic Peptide-Based Biologics Regulating HGF-MET.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impaired ligand-dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor.2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] 転移ニッチ形成におけるHGF-METシグナルの活性化と環状ペプチド阻害2022

Author(s)

Organizer

Data Source

[Presentation] HGF活性の遠隔制御によるがん転移ニッチ形成2022

Author(s)

Organizer

Data Source

[Presentation] HGF conversion in bronchial epithelial cells triggers pre-metastatic niche formation in the lung2021

Author(s)

Sato Hiroki 佐藤拓輝

Hiroki Sato 佐藤拓輝