Watanabe Kengo 渡邊謙吾

Researcher Number	20781727
Other IDs	https://orcid.org/0000-0002-0348-1634
Affiliation (Current)	2025: 徳島大学, 大学院医歯薬学研究部(医学域), 教授
Affiliation (based on the past Project Information) *help	2024: 徳島大学, 大学院医歯薬学研究部(医学域), 教授 2017 – 2019: 東京大学, 大学院薬学系研究科(薬学部), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related / Functional biochemistry
Keywords	Principal Investigator ASK3 / VRAC/LRRC8s / AVD / RVD / 細胞体積制御 / シグナル伝達 / ストレス / ゲノムワイドsiRNAスクリーニング / HICC / 高浸透圧ストレス

An exploration of the common principles in the cellular osmotic stress response and cell death inductionPrincipal Investigator
- Principal Investigator
  
  渡邊謙吾
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  The University of Tokushima
  The University of Tokyo
Genome-wide screen-based identification of non-selective hypertonicity-induced cation channelPrincipal Investigator
- Principal Investigator
  
  Watanabe Kengo
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo

All 2019 2018 2017

All Journal Article Presentation

[Journal Article] Cell volume regulation in cancer cell migration driven by osmotic water flow2019
- Author(s)
  Morishita Kazuhiro、Watanabe Kengo、Ichijo Hidenori
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 8 Pages: 2337-2347
- DOI
  10.1111/cas.14079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19469, KAKENHI-PROJECT-19K16067, KAKENHI-PROJECT-18H03995
[Journal Article] A PP6-ASK3 Module Coordinates the Bidirectional Cell Volume Regulation under Osmotic Stress2018
- Author(s)
  Watanabe Kengo、Umeda Tsuyoshi、Niwa Kuniyoshi、Naguro Isao、Ichijo Hidenori
- Journal Title
  
  Cell Reports
  
  Volume: 22 Issue: 11 Pages: 2809-2817
- DOI
  10.1016/j.celrep.2018.02.045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15086, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-15H04643, KAKENHI-PROJECT-16K15115, KAKENHI-PROJECT-18K19469, KAKENHI-PLANNED-26114009, KAKENHI-PROJECT-18H03995
[Journal Article] Cryo-EM structures of the human volume-regulated anion channel LRRC82018
- Author(s)
  Kasuya G, Nakane T, Yokoyama T, Jia Y, Inoue M, Watanabe K, Nakamura R, Nishizawa T, Kusakizako T, Tsutsumi A, Yanagisawa H, Dohmae N, Hattori M, Ichijo H, Yan Z, Kikkawa M, Shirouzu M, Ishitani R, Nureki O
- Journal Title
  
  Nat Struct Mol Biol.
  
  Volume: 25 Issue: 9 Pages: 797-804
- DOI
  10.1038/s41594-018-0109-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-17K15086, KAKENHI-PROJECT-16H06294
[Journal Article] The regulatory and signaling mechanisms of the ASK family2017
- Author(s)
  Nishida Takuto、Hattori Kazuki、Watanabe Kengo
- Journal Title
  
  Advances in Biological Regulation
  
  Volume: 66 Pages: 2-22
- DOI
  10.1016/j.jbior.2017.05.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15086, KAKENHI-PROJECT-16K18872
[Presentation] 浸透圧ストレス応答と細胞死制御における体積調節の共通性2019
- Author(s)
  井上雅斗，渡邊謙吾，一條秀憲
- Organizer
  第28回日本Cell Death学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16067
[Presentation] ASK3 and cell volume regulation: common mechanism in cellular osmotic stress response and cell death induction2019
- Author(s)
  渡邊謙吾
- Organizer
  東京大学医科学研究所国際共同利用・共同拠点事業平成30年度若手研究者シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K15086
[Presentation] ASK3 modulates cell volume under osmotic stress and beyond2018
- Author(s)
  渡邊謙吾，一條秀憲
- Organizer
  第10回シグナルネットワーク研究会
- Data Source
  KAKENHI-PROJECT-17K15086
[Presentation] ASK3不活性化における高浸透圧ストレスセンサー候補分子TRPML1の機能解析2018
- Author(s)
  森下和浩，渡邊謙吾，一條秀憲
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K15086
[Presentation] NAMPT and RNF146 regulate the bidirectional cell volume regulator, ASK3.2017
- Author(s)
  Watanabe, K., Naguro, I. and Ichijo, H.
- Organizer
  FASEB Science Research Conferences: NAD+ Metabolism and Signaling
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15086
[Presentation] PP6-ASK3 module is a key converter under bidirectional osmotic stress.2017
- Author(s)
  Watanabe, K., Naguro, I. and Ichijo, H.
- Organizer
  Consortium of Biological Sciences 2017 (ConBio2017)
- Data Source
  KAKENHI-PROJECT-17K15086

1. MORISHITA Kazuhiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. ISHITANI Ryuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 一條秀憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Watanabe Kengo 渡邊 謙吾

Research Projects

Research Products

Co-Researchers

An exploration of the common principles in the cellular osmotic stress response and cell death inductionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genome-wide screen-based identification of non-selective hypertonicity-induced cation channelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cell volume regulation in cancer cell migration driven by osmotic water flow2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A PP6-ASK3 Module Coordinates the Bidirectional Cell Volume Regulation under Osmotic Stress2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cryo-EM structures of the human volume-regulated anion channel LRRC82018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The regulatory and signaling mechanisms of the ASK family2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] 浸透圧ストレス応答と細胞死制御における体積調節の共通性2019

Author(s)

Organizer

Data Source

[Presentation] ASK3 and cell volume regulation: common mechanism in cellular osmotic stress response and cell death induction2019

Author(s)

Organizer

Data Source

[Presentation] ASK3 modulates cell volume under osmotic stress and beyond2018

Author(s)

Organizer

Data Source

[Presentation] ASK3不活性化における高浸透圧ストレスセンサー候補分子TRPML1の機能解析2018

Author(s)

Organizer

Data Source

[Presentation] NAMPT and RNF146 regulate the bidirectional cell volume regulator, ASK3.2017

Author(s)

Organizer

Data Source

[Presentation] PP6-ASK3 module is a key converter under bidirectional osmotic stress.2017

Author(s)

Organizer

Data Source

Watanabe Kengo 渡邊謙吾