Tanaka Hiroyoshi 田中啓祥

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TANAKA Hiroyoshi Y. 田中啓祥

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Researcher Number	20781941
Other IDs	https://orcid.org/0000-0003-1494-7716
Affiliation (Current)	2025: 岡山大学, 医歯薬学域, 助教
Affiliation (based on the past Project Information) *help	2021 – 2023: 岡山大学, 医歯薬学域, 助教 2020: 岡山大学, 医歯薬学総合研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 三次元培養法 / 薬物送達 / 線維化 / 細胞外基質 / 膵がん / 細胞外基質リモデリング / 間質 / 線維芽細胞 / 立体培養法

Development of therapeutic strategies to overcome fibrotic barriers to nanomedicine in pancreatic cancer via targeting of extracellular matrix signalingPrincipal Investigator
- Principal Investigator
  
  田中啓祥
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Okayama University
The use of 3D cell culture to study the mechanisms underlying aberrant ECM remodeling in pancreatic cancer stromaPrincipal Investigator
- Principal Investigator
  
  TANAKA Hiroyoshi Y.
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Okayama University

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Targeting ROCK2 improves macromolecular permeability in a 3D fibrotic pancreatic cancer microenvironment model2024
- Author(s)
  Tanaka Hiroyoshi Y.、Nakazawa Takuya、Miyazaki Takuya、Cabral Horacio、Masamune Atsushi、Kano Mitsunobu R.
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 369 Pages: 283-295
- DOI
  10.1016/j.jconrel.2024.03.041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06279, KAKENHI-PROJECT-23K27344
[Journal Article] Therapeutic Strategies to Overcome Fibrotic Barriers to Nanomedicine in the Pancreatic Tumor Microenvironment2023
- Author(s)
  Tanaka Hiroyoshi Y.、Nakazawa Takuya、Enomoto Atsushi、Masamune Atsushi、Kano Mitsunobu R.
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 3 Pages: 724-724
- DOI
  10.3390/cancers15030724
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16989, KAKENHI-PROJECT-23K24312
[Journal Article] Fibrotic elements within the tumor microenvironment and its implications for nano-drug delivery systems2021
- Author(s)
  田中啓祥、狩野光伸
- Journal Title
  
  Drug Delivery System
  
  Volume: 36 Issue: 4 Pages: 232-240
- DOI
  10.2745/dds.36.232
- NAID
  130008134399
- ISSN
  0913-5006, 1881-2732
- Year and Date
  2021-09-25
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-18H02797, KAKENHI-PROJECT-20K16989
[Journal Article] Modeling and Analysis of Disease Microenvironments with 3D Cell Culture Technology2021
- Author(s)
  Tanaka Hiroyoshi Y.
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 141 Issue: 5 Pages: 647-653
- DOI
  10.1248/yakushi.20-00219-4
- NAID
  130008032743
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2021-05-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16989
[Journal Article] Heterotypic 3D pancreatic cancer model with tunable proportion of fibrotic elements2020
- Author(s)
  Tanaka Hiroyoshi Y.、Kurihara Tsuyoshi、Nakazawa Takuya、Matsusaki Michiya、Masamune Atsushi、Kano Mitsunobu R.
- Journal Title
  
  Biomaterials
  
  Volume: 251 Pages: 120077-120077
- DOI
  10.1016/j.biomaterials.2020.120077
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16989, KAKENHI-PROJECT-18H02797
[Journal Article] Selection of Tumor models2020
- Author(s)
  Takashima Hiroki、Koga Yoshikatsu、Tsumura Ryo、Fuchigami Hirobumi、Matsumura Yasuhiro、Yasunaga Masahiro、Tanaka Hiroyoshi Y.、Kurihara Tsuyoshi、Kano Mitsunobu R.
- Journal Title
  
  Drug Delivery System
  
  Volume: 35 Issue: 5 Pages: 443-447
- DOI
  10.2745/dds.35.443
- NAID
  130007991323
- ISSN
  0913-5006, 1881-2732
- Year and Date
  2020-11-25
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-20K16989, KAKENHI-PROJECT-18H02797, KAKENHI-PROJECT-18K15297
[Presentation] 膵がん微小環境の立体培養モデルを利用した治療抵抗性獲得機構の解析2024
- Author(s)
  田中啓祥
- Organizer
  第13回ナノバイオ若手ネットワーキングシンポジウム
- Data Source
  KAKENHI-PROJECT-23K06279
[Presentation] 立体培養技術による膵がん微小環境研究への挑戦2024
- Author(s)
  田中啓祥
- Organizer
  第11回日本バイオマテリアル学会中四国ブロックシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23K06279
[Presentation] 膵がん微小環境の立体培養モデルによる獲得耐性機構の解析2024
- Author(s)
  田中啓祥
- Organizer
  第31回次世代医工学研究会
- Data Source
  KAKENHI-PROJECT-23K06279
[Presentation] 膵がん線維化障壁を克服するナノDDS 増強戦略の開発2023
- Author(s)
  田中啓祥
- Organizer
  第30回次世代医工学研究会
- Data Source
  KAKENHI-PROJECT-23K06279
[Presentation] 積層培養技術で挑む膵がん微小環境の研究2023
- Author(s)
  田中啓祥
- Organizer
  BioMedical Forum 2024
- Invited
- Data Source
  KAKENHI-PROJECT-23K06279
[Presentation] 膵がん線維化障壁をTRPP3阻害により克服するナノ薬剤送達戦略の開発2023
- Author(s)
  中澤拓也、田中啓祥、狩野光伸
- Organizer
  第39回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-23K06279
[Presentation] 細胞外基質シグナリングの標的化により膵がん線維化障壁を克服するナノ薬剤送達戦略の開発2022
- Author(s)
  田中啓祥、瀬野尾祐、狩野光伸
- Organizer
  第38回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20K16989
[Presentation] 積層培養技術による膵がん微小環境研究への挑戦2022
- Author(s)
  田中啓祥
- Organizer
  日本患者由来がんモデル研究会2022年度学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K16989
[Presentation] がん微小環境とイメージング2022
- Author(s)
  田中啓祥、狩野光伸
- Organizer
  MRIコラボ・ワークショップ2022
- Invited
- Data Source
  KAKENHI-PROJECT-20K16989
[Presentation] 膵がん線維化障壁をマクロピノサイトーシス経路阻害により克服するナノ薬剤送達戦略の開発2022
- Author(s)
  中澤拓也、田中啓祥、狩野光伸
- Organizer
  第38回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20K16989
[Presentation] 三次元培養法による膵がん線維化組織のモデル化および筋線維芽細胞分化機序の解析2022
- Author(s)
  中澤拓也、田中啓祥、狩野光伸
- Organizer
  日本薬学会第142回年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K16989
[Presentation] 線維化量を制御可能なヒト膵がん微小環境の三次元培養モデルの確立・解析とナノDDS研究への応用2021
- Author(s)
  田中啓祥、狩野光伸
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20K16989
[Presentation] Heterotypic 3D Cell Culture Model Of The Pancreatic Cancer Tumor Microenvironment With A Tunable Proportion Of Fibrotic Elements2021
- Author(s)
  Hiroyoshi Y. Tanaka, Mitsunobu R. Kano
- Organizer
  EACR Goodbye Flat Biology: Next Generation Cancer Models
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16989
[Presentation] Heterotypic 3D Culture Model of the Pancreatic Cancer Microenvironment with a Tunable Proportion of Fibrotic Elements2020
- Author(s)
  田中啓祥，正宗淳，狩野光伸
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K16989
[Presentation] 膵臓がん線維化組織の3D培養モデルを利用したナノ薬剤送達効率の解析2020
- Author(s)
  田中啓祥，狩野光伸
- Organizer
  第36回日本DDS学会
- Data Source
  KAKENHI-PROJECT-20K16989
[Presentation] 『三次元培養技術』を活用した線維化量調整可能な３D膵臓がんモデルの開発2020
- Author(s)
  狩野光伸，田中啓祥
- Organizer
  BioJapan 2020
- Data Source
  KAKENHI-PROJECT-20K16989

1. 正宗淳 (90312579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Tanaka Hiroyoshi 田中 啓祥

TANAKA Hiroyoshi Y. 田中 啓祥

Research Projects

Research Products

Co-Researchers

Development of therapeutic strategies to overcome fibrotic barriers to nanomedicine in pancreatic cancer via targeting of extracellular matrix signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The use of 3D cell culture to study the mechanisms underlying aberrant ECM remodeling in pancreatic cancer stromaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Targeting ROCK2 improves macromolecular permeability in a 3D fibrotic pancreatic cancer microenvironment model2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Therapeutic Strategies to Overcome Fibrotic Barriers to Nanomedicine in the Pancreatic Tumor Microenvironment2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fibrotic elements within the tumor microenvironment and its implications for nano-drug delivery systems2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Modeling and Analysis of Disease Microenvironments with 3D Cell Culture Technology2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Heterotypic 3D pancreatic cancer model with tunable proportion of fibrotic elements2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Selection of Tumor models2020

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Presentation] 膵がん微小環境の立体培養モデルを利用した治療抵抗性獲得機構の解析2024

Author(s)

Organizer

Data Source

[Presentation] 立体培養技術による膵がん微小環境研究への挑戦2024

Author(s)

Organizer

Data Source

[Presentation] 膵がん微小環境の立体培養モデルによる獲得耐性機構の解析2024

Author(s)

Organizer

Data Source

[Presentation] 膵がん線維化障壁を克服するナノDDS 増強戦略の開発2023

Author(s)

Organizer

Data Source

[Presentation] 積層培養技術で挑む膵がん微小環境の研究2023

Author(s)

Organizer

Data Source

[Presentation] 膵がん線維化障壁をTRPP3阻害により克服するナノ薬剤送達戦略の開発2023

Tanaka Hiroyoshi 田中啓祥

TANAKA Hiroyoshi Y. 田中啓祥