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Momose Fumiyasu  百瀬 文康

ORCIDConnect your ORCID iD *help
Researcher Number 20798326
Other IDs
Affiliation (Current) 2025: 三重大学, 医学系研究科, 産学官連携講座助教
Affiliation (based on the past Project Information) *help 2025: 三重大学, 医学系研究科, 産学官連携講座助教
2020 – 2023: 三重大学, 医学系研究科, 産学官連携講座助教
2018 – 2019: 三重大学, 医学系研究科, 特任助教(研究担当)
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related
Except Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords
Principal Investigator
がん免疫療法 / Antigen spreading / T細胞療法 / がんワクチン / T細胞エクソソーム / エクソソーム / がん抗原不均一性 / T細胞輸注療法 / ヒアルロン酸ナノゲル / CD8+T細胞 … More / ワクチン / Stem-like T cell / マクロファージ / T細胞 / がん悪性化制御 / CpG / がん間質 / miRNAs / miRNA過剰発現細胞モデル / IFN / ISGs / Type-I IFN / ISG / 間葉系幹細胞 / miRNA … More
Except Principal Investigator
Hybrid-TCR / TCR / CAR-T / 固形がん / キメラ抗原受容体 / MAGE-A4 / TCR様抗体 Less
  • Research Projects

    (6 results)
  • Research Products

    (30 results)
  • Co-Researchers

    (8 People)
  •  固形がんを対象とした新たなCAR-T療法の創出に挑む―Rethinking of T cell receptorー

    • Principal Investigator
      宮原 慶裕
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Mie University
  •  TCR-T-Vax療法のAntigen spreadingによる抗原不均一性がんの治癒と再発抑止機構の解明Principal Investigator

    • Principal Investigator
      百瀬 文康
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Mie University
  •  Analysis of tumor supressing function by Hybrid-TCR system

    • Principal Investigator
      赤堀 泰
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Mie University
  •  ヒアルロン酸誘導体がんワクチンのメモリーT細胞誘導作用とがん再発抑制機序の解明Principal Investigator

    • Principal Investigator
      百瀬 文康
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Mie University
  •  Elucidation of molecular mechanism of CpG-mediated suppression of malignant progression of tumors via activated T cell-released exosomesPrincipal Investigator

    • Principal Investigator
      Momose Fumiyasu
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Mie University
  •  Elucidation of ISG-mediated suppression of mesenchymal tumor stromal cells by miRNAs in human T cell-released exosomesPrincipal Investigator

    • Principal Investigator
      Momose Fumiyasu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Mie University

All 2024 2023 2022 2021 2019 2018

All Journal Article Presentation Patent

  • [Journal Article] A phase 1 trial of <scp>NY‐ESO</scp> ‐1‐specific <scp>TCR</scp> ‐engineered T‐cell therapy combined with a lymph node‐targeting nanoparticulate peptide vaccine for the treatment of advanced soft tissue sarcoma2023

    • Author(s)
      Ishihara Mikiya、Nishida Yoshihiro、Kitano Shigehisa、Kawai Akira、Takada Kohichi、Emori Makoto、Kageyama Shinichi、Shiku Hiroshi
    • Journal Title

      International Journal of Cancer

      Volume: 152 Issue: 12 Pages: 2554-2566

    • DOI

      10.1002/ijc.34453

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08080, KAKENHI-PROJECT-21H02995, KAKENHI-PROJECT-20K16411, KAKENHI-PROJECT-21K19561, KAKENHI-PROJECT-21K06690, KAKENHI-PROJECT-23K08700, KAKENHI-PROJECT-21K08682, KAKENHI-PROJECT-22K07277, KAKENHI-PROJECT-23K24180
  • [Journal Article] Exosomal regulation of lymphocyte homing to the gut2018

    • Author(s)
      Park Eun Jeong、Prajuabjinda Onmanee、Soe Zay Yar、Darkwah Samuel、Appiah Michael G.、Kawamoto Eiji、Momose Fumiyasu、Shiku Hiroshi、Shimaoka Motomu
    • Journal Title

      Blood Advances

      Volume: 3 Issue: 1 Pages: 1-11

    • DOI

      10.1182/bloodadvances.2018024877

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08917, KAKENHI-PROJECT-16K08581, KAKENHI-PROJECT-16K10957, KAKENHI-PROJECT-16K15759, KAKENHI-PROJECT-18K15275, KAKENHI-PROJECT-18H02622
  • [Patent] ヒアルロン酸誘導体、医薬組成物、及び医薬組成物の製造方法2023

    • Inventor(s)
      藪内 昂平, 中井 貴士, 百瀬 文康, 珠玖 洋
    • Industrial Property Rights Holder
      藪内 昂平, 中井 貴士, 百瀬 文康, 珠玖 洋
    • Industrial Property Rights Type
      特許
    • Filing Date
      2023
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22K07277
  • [Patent] ヒアルロン酸誘導体、医薬組成物、及び医薬組成物の製造方法2022

    • Inventor(s)
      藪内 昂平、中井 貴士、百瀬 文康、珠玖 洋
    • Industrial Property Rights Holder
      藪内 昂平、中井 貴士、百瀬 文康、珠玖 洋
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2022-088995
    • Filing Date
      2022
    • Data Source
      KAKENHI-PROJECT-20K16411
  • [Patent] ヒアルロン酸誘導体、医薬組成物、及び医薬組成物の製造方法2022

    • Inventor(s)
      藪内 昂平、中井 貴士、百瀬 文康、珠玖 洋
    • Industrial Property Rights Holder
      藪内 昂平、中井 貴士、百瀬 文康、珠玖 洋
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2022-088995
    • Filing Date
      2022
    • Data Source
      KAKENHI-PROJECT-22K07277
  • [Patent] 医薬組成物2022

    • Inventor(s)
      百瀬 文康、珠玖 洋、中井 貴士、藪内 昂平
    • Industrial Property Rights Holder
      百瀬 文康、珠玖 洋、中井 貴士、藪内 昂平
    • Industrial Property Rights Type
      特許
    • Filing Date
      2022
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22K07277
  • [Patent] 医薬組成物2022

    • Inventor(s)
      百瀬 文康、珠玖 洋、中井 貴士、藪内 昂平
    • Industrial Property Rights Holder
      百瀬 文康、珠玖 洋、中井 貴士、藪内 昂平
    • Industrial Property Rights Type
      特許
    • Filing Date
      2022
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20K16411
  • [Patent] 医薬組成物2021

    • Inventor(s)
      百瀬 文康, 珠玖 洋
    • Industrial Property Rights Holder
      百瀬 文康, 珠玖 洋
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-091520
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-20K16411
  • [Presentation] A novel cancer vaccine based on hyaluronic acid nanogel drives a potent and sustainable antitumor immunity against metastatic- and ICI-resistant-tumors with long lasting memory CD8+ T cells2024

    • Author(s)
      Fumiyasu Momose, Takashi Nakai, Kohei Yabuuchi, Makiko Yamane, Tae Hayashi, Linan Wang, Yoshiyuki Nakagawa, Shogo Aso, Toru Katsumata, Tsuyoshi Shimoboji, Yoshihiro Miyahara
    • Organizer
      第52回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K07277
  • [Presentation] ヒアルロン酸ナノゲルを用いたがんワクチンのT細胞性免疫誘導を介した抗腫瘍・再発抑制作用2023

    • Author(s)
      百瀬 文康, 中井 貴士, 藪内 昂平, 山根 真妃子, 林 妙, 王 立楠, 中川 慶之, 麻生 尚吾, 勝又 徹, 下房地 剛, 宮原 慶裕
    • Organizer
      第27回日本ワクチン学会 第64回日本臨床ウイルス学会 合同学術集会
    • Data Source
      KAKENHI-PROJECT-22K07277
  • [Presentation] ヒアルロン酸ナノゲルを基盤とした新規がんワクチンデリバリーシステムとTCR-T細胞輸注療法を用いた複合的がん免疫療法の研究開発2023

    • Author(s)
      百瀬 文康, 中井 貴士, 藪内 昂平, 山根 真妃子, 林 妙, 王 立楠, 中川 慶之, 麻生 尚吾, 勝又 徹, 下房地 剛, 宮原 慶裕
    • Organizer
      第39回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K07277
  • [Presentation] Hyaluronic acid nanogel cancer vaccine: powerful and versatile priming tool for combinational T cell therapy2023

    • Author(s)
      Takashi Nakai, Fumiyasu Momose, Kohei Yabuuchi, Shogo Aso, Toru Katsumata, Tsuyoshi Shimoboji, Yoshihiro Miyahara
    • Organizer
      AAPS 2023 PHarmSCi 360
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07277
  • [Presentation] Analysis of mechanism of antitumor effect with long lasting memory induced by a novel cancer vaccine based on hyaluronic acid nanogel2023

    • Author(s)
      百瀬 文康, 中井 貴士, 藪内 昂平, 山根 真妃子, 林 妙, 王 立楠, 中川 慶之, 麻生 尚吾, 勝又 徹, 下房地 剛, 宮原 慶裕
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K07277
  • [Presentation] 強力なメモリーCD8+ T細胞を誘導し得る新規ヒアルロン酸ナノゲルがんワクチンの抗腫瘍作用・再発抑制機序の解明2023

    • Author(s)
      百瀬 文康, 中井 貴士, 藪内 昂平, 山根 真妃子, 林 妙, 王 立楠, 中川 慶之, 麻生 尚吾, 勝又 徹, 下房地 剛, 宮原 慶裕
    • Organizer
      第27回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-22K07277
  • [Presentation] Hyaluronic acid nanogel based cancer vaccine, in combination with adoptive T cell therapy totally suppresses ICI resistant-tumors2022

    • Author(s)
      Fumiyasu Momose, ◯Takashi Nakai, Kohei Yabuuchi, Toru Katsumata, Tuyoshi Shimoboji, Hiroshi Shiku
    • Organizer
      SITC 37th Annual Meeting & Pre-Conference Programs
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16411
  • [Presentation] ヒアルロン酸ナノゲルワクチンはPmel-1由来TCR-T細胞との併用によりgp-100 tet+ CTLを強力に誘導し、B16F10メラノーマを退縮させる2022

    • Author(s)
      百瀬 文康、中井 貴士、藪内 昂平、中川 慶之、麻生 尚吾、勝又 徹、下房地 剛、珠玖 洋
    • Organizer
      第26回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20K16411
  • [Presentation] Hyaluronic acid nanogel cancer vaccine strongly induce gp100 specific CTL and regress B16F10 melanoma with TCR-T therapy2022

    • Author(s)
      百瀬 文康、中井 貴士、藪内 昂平、勝又 徹、珠玖 洋
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K07277
  • [Presentation] ヒアルロン酸ナノゲルを用いたペプチドがんワクチン開発2022

    • Author(s)
      中井 貴士、百瀬 文康、藪内 昂平、中川 慶之、麻生 尚吾、勝又 徹、下房地 剛、珠玖 洋
    • Organizer
      第26回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20K16411
  • [Presentation] ヒアルロン酸ナノゲルを用いたペプチドがんワクチン開発2022

    • Author(s)
      中井 貴士、百瀬 文康、藪内 昂平、中川 慶之、麻生 尚吾、勝又 徹、下房地 剛、珠玖 洋
    • Organizer
      第26回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-22K07277
  • [Presentation] ヒアルロン酸ナノゲルワクチンはPmel-1由来TCR-T細胞との併用によりgp-100 tet+ CTLを強力に誘導し、B16F10メラノーマを退縮させる2022

    • Author(s)
      百瀬 文康、中井 貴士、藪内 昂平、中川 慶之、麻生 尚吾、勝又 徹、下房地 剛、珠玖 洋
    • Organizer
      第26回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-22K07277
  • [Presentation] Combination Immunotherapy of Adoptive T Cell Therapy with Hyaluronic Acid (HA) Nanogel Based Cancer Vaccine2022

    • Author(s)
      Hiroshi Shiku, Takashi Nakai, Fumiyasu Momose, Kohei Yabuuchi, Yoshiyuki Nakagawa, Shogo Aso, Toru Katsumata,Tuyoshi Shimoboji
    • Organizer
      The 7th Annual CAR-TCR Summit
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07277
  • [Presentation] Hyaluronic acid nanogel based cancer vaccine, in combination with adoptive T cell therapy totally suppresses ICI resistant-tumors2022

    • Author(s)
      Fumiyasu Momose, ◯Takashi Nakai, Kohei Yabuuchi, Toru Katsumata,Tuyoshi Shimoboji, Hiroshi Shiku
    • Organizer
      SITC 37th Annual Meeting & Pre-Conference Programs
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07277
  • [Presentation] Combination Immunotherapy of Adoptive T Cell Therapy with Hyaluronic Acid (HA) Nanogel Based Cancer Vaccine2022

    • Author(s)
      Hiroshi Shiku, Takashi Nakai, Fumiyasu Momose, Kohei Yabuuchi, Yoshiyuki Nakagawa, Shogo Aso, Toru Katsumata, Tuyoshi Shimoboji
    • Organizer
      The 7th Annual CAR-TCR Summit
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16411
  • [Presentation] Hyaluronic acid nanogel cancer vaccine strongly induce gp100 specific CTL and regress B16F10 melanoma with TCR-T therapy2022

    • Author(s)
      百瀬 文康、中井 貴士、藪内 昂平、勝又 徹、珠玖 洋
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K16411
  • [Presentation] HANG cancer vaccine rejects anti PD-1 therapy resistant-tumor via potent neoantigen-specific CTL in draining lymph node2021

    • Author(s)
      百瀬 文康, 中井 貴士, 白木 広治, 福本 圭介, 勝又 徹, 藪内 昂平, 村岡 大輔, 池田 裕明, 珠玖 洋
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K16411
  • [Presentation] ヒアルロン酸誘導体を基盤とした新規がんワクチンデリバリーシステムによる腫瘍抗原特異的CTL及びメモリーT細胞誘導作用と抗腫瘍・再発抑制効果の検討2021

    • Author(s)
      百瀬 文康, 中井 貴士, 白木 広治, 福本 圭介, 勝又 徹, 藪内 昂平, 村岡 大輔, 池田 裕明, 珠玖 洋
    • Organizer
      第25回日本ワクチン学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K16411
  • [Presentation] ヒアルロン酸ナノゲルワクチンとTCR-T細胞併用は所属リンパ節で強力に腫瘍抗原特異的CTLを誘導し抗PD-1抵抗性腫瘍を消失させる2021

    • Author(s)
      百瀬 文康, 中井 貴士, 白木 広治, 福本 圭介, 勝又 徹, 藪内 昂平, 村岡 大輔, 池田 裕明, 珠玖 洋
    • Organizer
      第25回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20K16411
  • [Presentation] Preparation of human T cell-derived exosomes with high purity and quality for clinical use against advanced tumor2019

    • Author(s)
      Naohiro Seo, Junko Nakamura, Fumiyasu Momose, Asako Shimoda, Kazunari Akiyoshi, Tsuguhiro Kaneda, Hiroshi Shiku
    • Organizer
      第78回日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-18K15275
  • [Presentation] CTLの放出するエクソソームの一部が間葉系細胞で構成されるがん間質傷害に関与する2019

    • Author(s)
      瀬尾 尚宏, 中村 純子, 百瀬 文康, 下田 麻子, 秋吉 一成, 金田 次弘, 珠玖 洋
    • Organizer
      第23回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-18K15275
  • [Presentation] Only a portion of the T cell-released exosomes has a capacity to destruct mesenchymal tumor stroma2019

    • Author(s)
      Naohiro Seo, Tsuguhiro Kaneda, Junko Nakamura, Fumiyasu Momose, Kazunari Akiyoshi, Hiroshi Shiku
    • Organizer
      International Society for Extracellular Vesicles 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15275
  • 1.  赤堀 泰 (80221711)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  三輪 啓志 (00209967)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  藤原 弘 (20398291)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  瀬尾 尚宏 (50283354)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  宮原 慶裕 (10582083)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  KAWAMOTO Eiji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  島岡 要
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  高田 弘一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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