UZU Miaki 宇津美秋

… Alternative Names

Uzu Miaki 宇津美秋

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Researcher Number	20802896
Other IDs
Affiliation (Current)	2025: 千葉大学, 大学院薬学研究院, 助教
Affiliation (based on the past Project Information) *help	2025: 千葉大学, 大学院薬学研究院, 助教 2019 – 2021: 国立研究開発法人農業・食品産業技術総合研究機構, 生物機能利用研究部門, 研究員 2018: 国立研究開発法人国立がん研究センター, 研究所, 特任研究員 2017: 国立研究開発法人国立がん研究センター, 研究所, 特別研究員(PD)
Review Section/Research Field	Principal Investigator Basic Section 48030:Pharmacology-related / Basic Section 47040:Pharmacology-related / Applied pharmacology
Keywords	Principal Investigator がん悪液質 / 薬物治療 / コラーゲンビトリゲル膜 / アストロサイト / セラミド代謝 / 肝臓 / アポトーシス / 薬物感受性 / がん / コネキシン … More / 血管透過性 / ヒト微小血管内皮細胞 / コラーゲンビトリゲル / 培養モデル / 血液脳関門 / プリン代謝 / グリア / 炎症 / プリンヌクレオチド代謝 Less

Involvement of ceramide metabolism in the liver in pathogenesis of cancer cachexiaPrincipal Investigator
- Principal Investigator
  
  宇津美秋
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Chiba University
Elucidation of the activation mechanism of astrocytes under cancer cachexic condition by using a novel cell culture modelPrincipal Investigator
- Principal Investigator
  
  Uzu Miaki
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  National Agriculture and Food Research Organization
Development of a novel therapy for cancer cachexia targeting the purine metabolism in the central nervous systemPrincipal Investigator
- Principal Investigator
  
  Uzu Miaki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  National Agriculture and Food Research Organization
  National Cancer Center Japan
ギャップ結合を介したシグナル伝達の生理学的意義に関する薬理学的研究Principal Investigator
- Principal Investigator
  
  宇津美秋
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Applied pharmacology
- Research Institution
  National Cancer Center Japan
  Chiba University

All 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Patent

[Journal Article] Metabolome Shift in Both Metastatic Breast Cancer Cells and Astrocytes Which May Contribute to the Tumor Microenvironment2021
- Author(s)
  Sato Hiromi、Shimizu Ayaka、Okawa Toya、Uzu Miaki、Goto Momoko、Hisaka Akihiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 14 Pages: 7430-7430
- DOI
  10.3390/ijms22147430
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16139
[Journal Article] Novel microvascular endothelial model utilizing a collagen vitrigel membrane and its advantages for predicting histamine-induced microvascular hyperpermeability2020
- Author(s)
  Uzu M, Takezawa T
- Journal Title
  
  Journal of Pharmacological and Toxicological Methods
  
  Volume: 106 Pages: 106916-106916
- DOI
  10.1016/j.vascn.2020.106916
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16139
[Journal Article] The Japanese herbal medicine Hangeshashinto enhances oral keratinocyte migration to facilitate healing of chemotherapy-induced oral ulcerative mucositis.2020
- Author(s)
  103.Miyano, K., Eto, M., Hitomi, S., Matsumoto, T., Hasegawa, S., Hirano, A., Nagabuchi, K., Asai, N., Uzu, M., Nonaka, M., Omiya, Y., Kaneko, A., Ono, K., Fujii, H., Higami, Y., Kono, T., Uezono, Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 10 Issue: 1 Pages: 625-625
- DOI
  10.1038/s41598-019-57192-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16497, KAKENHI-PROJECT-18K15037
[Journal Article] A novel strategy for treatment of cancer cachexia targeting xanthine oxidase in the brain2019
- Author(s)
  Uzu Miaki、Nonaka Miki、Miyano Kanako、Sato Hiromi、Kurebayashi Nagomi、Yanagihara Kazuyoshi、Sakurai Takashi、Hisaka Akihiro、Uezono Yasuhito
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 140 Issue: 1 Pages: 109-112
- DOI
  10.1016/j.jphs.2019.04.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07404, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-16H04667, KAKENHI-PROJECT-18K15037
[Journal Article] Possible biased analgesic of hydromorphone through the G protein-over β-arrestin-mediated pathway: cAMP, CellKey?, and receptor internalization analyses2019
- Author(s)
  Manabe Sei、Miyano Kanako、Fujii Yuriko、Ohshima Kaori、Yoshida Yuki、Nonaka Miki、Uzu Miaki、Matsuoka Yoshikazu、Sato Tetsufumi、Uezono Yasuhito、Morimatsu Hiroshi
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 140 Issue: 2 Pages: 171-177
- DOI
  10.1016/j.jphs.2019.06.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07404, KAKENHI-PROJECT-16K08568, KAKENHI-PROJECT-18K15037
[Journal Article] Trichostatin A modulates cellular metabolism in renal cell carcinoma to enhance sunitinib sensitivity2019
- Author(s)
  Sato Hiromi、Uzu Miaki、Kashiba Tatsuro、Fujiwara Takuya、Hatakeyama Hiroto、Ueno Koichi、Hisaka Akihiro
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 847 Pages: 143-157
- DOI
  10.1016/j.ejphar.2019.01.040
- Data Source
  KAKENHI-PROJECT-18K15037
[Journal Article] Multifunctional Actions of Ninjinyoeito, a Japanese Kampo Medicine: Accumulated Scientific Evidence Based on Experiments With Cells and Animal Models, and Clinical Studies2018
- Author(s)
  Miyano Kanako、Nonaka Miki、Uzu Miaki、Ohshima Kaori、Uezono Yasuhito
- Journal Title
  
  Frontiers in Nutrition
  
  Volume: 5 Pages: 93-93
- DOI
  10.3389/fnut.2018.00093
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15037, KAKENHI-PROJECT-16K21645
[Journal Article] Conflicting Roles of Connexin43 in Tumor Invasion and Growth in the Central Nervous System.2018
- Author(s)
  Uzu M, Sin WC, Shimizu A, Sato H.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 19 Issue: 4 Pages: 1159-1173
- DOI
  10.3390/ijms19041159
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16J04170, KAKENHI-PROJECT-18K15037
[Journal Article] Modulation of synaptic inputs in magnocellular neurones in a rat model of cancer cachexia2018
- Author(s)
  Yokoyama Toru、Terawaki Kiyoshi、Minami Kouichiro、Miyano Kanako、Nonaka Miki、Uzu Miaki、Kashiwase Yohei、Yanagihara Kazuyoshi、Ueta Yoichi、Uezono Yasuhito
- Journal Title
  
  Journal of Neuroendocrinology
  
  Volume: 30 Issue: 9
- DOI
  10.1111/jne.12630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15037, KAKENHI-PROJECT-17H04027, KAKENHI-PROJECT-15K08215, KAKENHI-PROJECT-16K21645
[Journal Article] Leukemia inhibitory factor via the Toll-like receptor 5 signaling pathway involves aggravation of cachexia induced by human gastric cancer-derived 85As2 cells in rats2018
- Author(s)
  Terawaki Kiyoshi、Kashiwase Yohei、Uzu Miaki、Nonaka Miki、Sawada Yumi、Miyano Kanako、Higami Yoshikazu、Yanagihara Kazuyoshi、Yamamoto Masahiro、Uezono Yasuhito
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 78 Pages: 34748-34764
- DOI
  10.18632/oncotarget.26190
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15037, KAKENHI-PROJECT-15K08215, KAKENHI-PROJECT-16K21645
[Journal Article] Sodium butyrate enhances the growth inhibitory effect of sunitinib in human renal cell carcinoma cells.2017
- Author(s)
  Sato H, Uzu M, Kashiba T, Suzuki R, Fujiwara T, Okuzawa H, Ueno K.
- Journal Title
  
  Oncol Lett.
  
  Volume: 14 Issue: 1 Pages: 937-943
- DOI
  10.3892/ol.2017.6217
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16J04170
[Journal Article] Connexin 43 enhances Bax activation via JNK activation in sunitinib-induced apoptosis in mesothelioma cells.2017
- Author(s)
  Uzu M, Sato H, Shimizu A, Shibata Y, Ueno K, Hisaka A.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 134 Issue: 2 Pages: 101-107
- DOI
  10.1016/j.jphs.2017.05.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16J04170
[Journal Article] Sodium butyrate enhances the growth inhibitory effect of sunitinib in human renal cell carcinoma cells.2017
- Author(s)
  Sato H, Uzu M, Kashiba T, Suzuki R, Fujiwara T, Okuzawa H, Ueno K.
- Journal Title
  
  Oncology Letters
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16J04170
[Patent] 血液組織関門インビトロモデル、及び薬物の血液組織関門移行性評価方法2019
- Inventor(s)
  竹澤俊明、宇津美秋
- Industrial Property Rights Holder
  農業・食品産業技術総合研究機構
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-190832
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K15037
[Presentation] 若手薬学研究者から見たコラーゲンビトリゲル膜の魅力：非臨床試験を加速させるin vitroバリア機能薬理学の提唱2021
- Author(s)
  宇津美秋, 竹澤俊明
- Organizer
  第65回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-20K16139
[Presentation] 内皮バリアを標的とした創薬に有用な培養モデルの開発：コラーゲンビトリゲル膜を介した微小血管内皮細胞と線維芽細胞の共培養2021
- Author(s)
  宇津美秋, 竹澤俊明
- Organizer
  第16回ナノ・バイオメディカル学会大会
- Data Source
  KAKENHI-PROJECT-20K16139
[Presentation] コラーゲンビトリゲル膜を利用した微小血管内皮モデルの構築とその炎症病態を外挿する細胞アッセイ系としての有用性2021
- Author(s)
  宇津美秋, 竹澤俊明
- Organizer
  日本組織培養学会第93回大会
- Data Source
  KAKENHI-PROJECT-20K16139
[Presentation] Development of tissue-specific histamine-responsive vascular endothelial models using a collagen vitrigel membrane2020
- Author(s)
  宇津美秋
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K15037
[Presentation] ”Vascular Endothelial Model Constructed on a Collagen Vitrigel Membrane” Useful for Extrapolating the Histamine-Induced Vascular Hyperpermeability2020
- Author(s)
  Uzu M, Takezawa T
- Organizer
  World Congress on In Vitro Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16139
[Presentation] ヒト体内の毛細血管バリアを「変動させる因子の同定」および「透過する化合物の探索」に有用な培養モデルの提案：コラーゲンビトリゲル膜を介した血管内皮細胞と非血管内皮細胞の共培養2020
- Author(s)
  宇津　美秋、竹澤　俊明
- Organizer
  第143回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20K16139
[Presentation] Microvascular endothelial model that can predict the inflammatory responses in human microvessels with high reproducibility: Culture model of an hCMEC/D3 cell line fabricated in a collagen vitrigel membrane chamber2020
- Author(s)
  Uzu M, Takezawa T
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K16139
[Presentation] コラーゲンビトリゲル膜を利用したヒト血液脳関門培養モデルの開発2020
- Author(s)
  宇津美秋
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K15037
[Presentation] 炎症誘発物質による血管透過性変化の予測に有用な「コラーゲンビトリゲル膜上に構築した血管内皮培養モデル」2019
- Author(s)
  宇津美秋
- Organizer
  日本動物実験代替法学会第32回大会
- Data Source
  KAKENHI-PROJECT-18K15037
[Presentation] A novel strategy for treatment of cancer cachexia targeting the altered purine metabolism in the brain2019
- Author(s)
  Uzu M, Nonaka M, Miyano K, Sato H, Kurebayashi N, Murayama T, Sakurai T, Hisaka A, Uezono Y.
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K15037
[Presentation] Voluntary wheel running may improve cardiac dysfunction in experimental mouse model of cancer-induced cachexia2019
- Author(s)
  Ueno S, Nonaka M, Kakigi R, Uzu M, Kurebayashi N, Murayama T, Terawaki K, Sakurai T, Uezono Y.
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K15037
[Presentation] コラーゲンビトリゲル膜を利用したヒスタミン応答性血管内皮モデルの開発2019
- Author(s)
  宇津美秋
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2019
- Data Source
  KAKENHI-PROJECT-18K15037
[Presentation] Development of tissue-specific vascular endothelial models using a collagen vitrigel membrane and their histamine responsiveness2019
- Author(s)
  宇津美秋
- Organizer
  日本薬物動態学会第34回年会つくば
- Data Source
  KAKENHI-PROJECT-18K15037
[Presentation] コラーゲンビトリゲル膜チャンバー内で培養したヒト血管内皮細胞のバリア機能の解析：炎症血管内皮モデルの開発を目指して2019
- Author(s)
  宇津美秋
- Organizer
  日本組織培養学会第92回大会
- Data Source
  KAKENHI-PROJECT-18K15037
[Presentation] 新規がん悪液質治療薬開発を目指した悪液質モデルマウス脳内代謝変化の解析2018
- Author(s)
  宇津美秋, 野中美希, 宮野加奈子, 佐藤洋美, 呉林なごみ, 村山尚, 櫻井隆, 樋坂章博, 上園保仁
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16J04170
[Presentation] 中枢性プリン代謝変化を標的とした新規がん悪液質治療薬開発2018
- Author(s)
  宇津美秋, 野中美希, 宮野加奈子, 佐藤洋美, 呉林なごみ, 村山尚, 櫻井隆, 樋坂章博, 上園保仁.
- Organizer
  第4回　次世代を担う若手のためのレギュラトリーサイエンスフォーラム
- Data Source
  KAKENHI-PROJECT-18K15037
[Presentation] Characterization of the properties of four opioid analgesics approved in Japan with cells stably expressing μORs using the CellKey and GloSensor cAMP assay systems2018
- Author(s)
  Manabe S, Miyano K, Ogino T, Oshima K, Uzu M, Nonaka M, Matsuoka Y, Sato T, Morimatsu H, Uezono Y.
- Organizer
  WCP2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15037
[Presentation] モルヒネの3次元構造をもとに設計された新規化合物の各オピオイド受容体に対するアゴニスト活性の解析－CellKeyシステムによる細胞アッセイを用いて－2018
- Author(s)
  染谷僚人, 芦沢夏鈴, 江藤萌子, 平山重人,伊藤謙之介, 宇津美秋, 野中美希, 宮野加奈子, 藤井秀明, 上園保仁
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16J04170
[Presentation] Therapeutic effects of ghrelin and des-acyl ghrelin on anthracycline doxorubicin-induced cardiac toxicity2018
- Author(s)
  Nonaka M, Kurebayashi N, Murayama T, Sugihara M, Hosoda H, Kishida S, Uzu M, Kangawa K, Sakurai T, Uezono Y.
- Organizer
  WCP2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15037
[Presentation] 漢方薬半夏瀉心湯が抗がん剤のがん細胞増殖抑制作用に及ぼす影響の解析2018
- Author(s)
  永淵かおり, 平野絢音, 江藤萌子, 宮野加奈子, 大宮雄司, 宇津美秋, 野中美希, 樋上賀一, 藤井秀明, 上園保仁.
- Organizer
  第12回日本緩和医療薬学会年会
- Data Source
  KAKENHI-PROJECT-18K15037
[Presentation] 立体的かつ構造改変が容易な創薬候補化合物群の探索－CellKeyアッセイシステムを用いて－2018
- Author(s)
  芦沢夏鈴, 梅本翔, 染谷僚人, 唐木文霞, 江藤萌子, 野中美希, 宇津美秋, 宮野加奈子, 平山重人, 藤井秀明,上園保仁
- Organizer
  第138回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16J04170
[Presentation] A novel strategy for treatment of cancer cachexia targeting for alteration of the purine metabolism in the brain2018
- Author(s)
  Uzu M, Nonaka M, Miyano K, Sato H, Uezono Y.
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K15037
[Presentation] Novel strategy for treatment of cancer cachexia based on metabolic alteration in central nervous system in a mouse model2018
- Author(s)
  Uzu M, Nonaka M, Miyano K, Sato H, Kurebayashi N, Murayama T, Sakurai T, Hisaka A, Uezono Y.
- Organizer
  WCP2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15037
[Presentation] 各種医療麻薬の鎮痛効果におけるオピオイド二量体受容体の役割～μ、κおよび新規作製μ/κ二量体受容体安定発現細胞を用いた比較解析～2018
- Author(s)
  大島佳織, 宮野加奈子, 石橋尚人, 大道容子, 藤井百合子, 真鍋星, 宇津美秋, 野中美希, 宮野加奈子, 藤井秀明, 吉澤一巳, 上園保仁.
- Organizer
  第12回日本緩和医療薬学会年会
- Data Source
  KAKENHI-PROJECT-18K15037
[Presentation] Communication between astrocyte and metastasized cancer cell focused on changes of cellular metabolism2018
- Author(s)
  Sato H, Shimizu A, Uzu M, Ueno K, Hisaka A.
- Organizer
  WCP2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15037
[Presentation] Human stomach cancer cell line 85As2 induced cancer cachexia associated with cardiac dysfunction2018
- Author(s)
  Nonaka M, Uzu M, Terawaki K, Miyano K, Uezono Y.
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K15037
[Presentation] Epigenetic regulation by trichostatin A shifted cellular metabolism in renal cell carcinoma2017
- Author(s)
  Sato H, Fujiwara T, Hatakeyama H, Uzu M, Ueno K, and Hisaka A.
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎市
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16J04170
[Presentation] 間葉系幹細胞の全身性投与は神経障害性疼痛を緩和する2017
- Author(s)
  池畑農, 宮野加奈子, 大島佳織, 吉田有輝, 隠岐勝幸, 白石成二, 野中美希, 宇津美秋, 吉澤一巳, 樋上賀一,上園保仁
- Organizer
  第137回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-16J04170
[Presentation] Study on activation mechanism of Bax by connexin 43 in process of apoptosis induced by sunitinib2017
- Author(s)
  Uzu M, Sato H, Shimizu A, and Hisaka A.
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎市
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16J04170
[Presentation] 脂肪細胞および臍帯組織由来ヒト間葉系幹細胞は神経障害性疼痛を改善させる2017
- Author(s)
  宮野加奈子, 池畑農, 隠岐勝幸, 白石成二, 野中美希, 宇津美秋, 上園保仁
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16J04170
[Presentation] エピジェネティック調節薬の代謝調節を介したスニチニブ感受性の増強作用2017
- Author(s)
  佐藤洋美, 加柴達朗, 藤原拓也, 宇津美秋, 清水彩花, 畠山浩人, 樋坂章博
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2017
- Data Source
  KAKENHI-PROJECT-16J04170
[Presentation] 口内炎に有効な漢方薬のがん増殖および口腔ケラチノサイトの損傷治癒効果に及ぼす影響の解析2017
- Author(s)
  江藤萌子, 宮野加奈子, 寺脇潔, 野中美希, 宇津美秋, 上園保仁
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16J04170
[Presentation] エピジェネティック調節薬の代謝調節を介したスニチニブ感受性の増強作用2017
- Author(s)
  佐藤洋美, 加柴達朗, 藤原拓也, 宇津美秋, 清水彩花, 畠山浩人, 樋坂章博
- Organizer
  生体機能と創薬シンポジウム2017
- Data Source
  KAKENHI-PROJECT-16J04170
[Presentation] がん患者の口内炎に処方される漢方薬の損傷治癒機能解析ならびにがん増殖能に対する影響～ヒト口腔上皮細胞および種々のがん細胞を用いて～2017
- Author(s)
  江藤萌子、平野絢音、永渕かおり、田崎若葉、宮野加奈子、大宮雄司、野中美希、宇津美秋、羽田紀康、藤井秀明、樋上賀一、上園保仁
- Organizer
  第2回日本がんサポーティブケア学会学術集会
- Data Source
  KAKENHI-PROJECT-16J04170
[Presentation] ドキソルビシンの心毒性に対するデスアシルグレリン治療効果の検討2017
- Author(s)
  野中美希, 宮野加奈子, 岸田昭世, 白石成二, 宇津美秋, 上園保仁
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16J04170
[Presentation] The injurious interaction between breast cancer cells and astrocytes focusing on their intracellular metabolism2017
- Author(s)
  清水彩花, 佐藤洋美, 宇津美秋, 樋坂章博
- Organizer
  第11回次世代を担う若手医療薬科学シンポジウム
- Data Source
  KAKENHI-PROJECT-16J04170
[Presentation] トリコスタチン A による腎細胞がんの代謝調節がスニチニブ抵抗性を改善する可能性2016
- Author(s)
  佐藤洋美, 藤原拓也, 宇津美秋.
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16J04170
[Presentation] Trichostatin A modulates cellular metabolism in renal cell carcinoma which may decline sunitinib resistance2016
- Author(s)
  Sato H, Kashiba T, Fujiwara T, Uzu M, and Hisaka A
- Organizer
  第10回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  前橋市
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-16J04170

1. 中村浩之 (20447311)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 野中美希

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 宮野加奈子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 上園保仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

UZU Miaki 宇津 美秋

Uzu Miaki 宇津 美秋

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Involvement of ceramide metabolism in the liver in pathogenesis of cancer cachexiaPrincipal Investigator

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Elucidation of the activation mechanism of astrocytes under cancer cachexic condition by using a novel cell culture modelPrincipal Investigator

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Development of a novel therapy for cancer cachexia targeting the purine metabolism in the central nervous systemPrincipal Investigator

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ギャップ結合を介したシグナル伝達の生理学的意義に関する薬理学的研究Principal Investigator

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[Journal Article] Metabolome Shift in Both Metastatic Breast Cancer Cells and Astrocytes Which May Contribute to the Tumor Microenvironment2021

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[Journal Article] Novel microvascular endothelial model utilizing a collagen vitrigel membrane and its advantages for predicting histamine-induced microvascular hyperpermeability2020

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[Journal Article] The Japanese herbal medicine Hangeshashinto enhances oral keratinocyte migration to facilitate healing of chemotherapy-induced oral ulcerative mucositis.2020

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[Journal Article] A novel strategy for treatment of cancer cachexia targeting xanthine oxidase in the brain2019

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[Journal Article] Possible biased analgesic of hydromorphone through the G protein-over β-arrestin-mediated pathway: cAMP, CellKey?, and receptor internalization analyses2019

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[Journal Article] Trichostatin A modulates cellular metabolism in renal cell carcinoma to enhance sunitinib sensitivity2019

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[Journal Article] Multifunctional Actions of Ninjinyoeito, a Japanese Kampo Medicine: Accumulated Scientific Evidence Based on Experiments With Cells and Animal Models, and Clinical Studies2018

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[Journal Article] Conflicting Roles of Connexin43 in Tumor Invasion and Growth in the Central Nervous System.2018

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[Journal Article] Modulation of synaptic inputs in magnocellular neurones in a rat model of cancer cachexia2018

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[Journal Article] Leukemia inhibitory factor via the Toll-like receptor 5 signaling pathway involves aggravation of cachexia induced by human gastric cancer-derived 85As2 cells in rats2018

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[Journal Article] Sodium butyrate enhances the growth inhibitory effect of sunitinib in human renal cell carcinoma cells.2017

UZU Miaki 宇津美秋

Uzu Miaki 宇津美秋

[Patent] 血液組織関門インビトロモデル、及び薬物の血液組織関門移行性評価方法2019