Ishikawa Tomoe 石川智愛

Researcher Number	20804587
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 講師(非常勤)
Affiliation (based on the past Project Information) *help	2025: 慶應義塾大学, 医学部(信濃町), 講師(非常勤) 2017 – 2020: 慶應義塾大学, 医学部(信濃町), 助教
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / Basic Section 48030:Pharmacology-related / Biological pharmacy
Keywords	Principal Investigator 記憶の再生 / 副嗅覚系 / 脳神経連関 / 神経活動・脳波 / グリア細胞 / 記憶・学習 / 髄膜リンパ管 / 血管周辺スペース / 硬膜リンパ管 / 脳波 … More / 血管周囲腔 / 記憶 / リンパ管 / SW-R / 大規模スパインカルシウムイメージング / 海馬CA1野 / 海馬CA1野神経細胞 / 機能的スパインイメージング / 記憶再生 / 樹状突起スパイン / クラスター入力 / 海馬 / シークエンス入力 / スパイン / シナプス入力 / sharp waves/ripples Less

Investigating the Development of Neuroimmune InteractionsPrincipal Investigator
- Principal Investigator
  
  石川智愛
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Keio University
Mechanism of cognitive impairment after ligation of meningeal lymphatic vesselsPrincipal Investigator
- Principal Investigator
  
  Ishikawa Tomoe
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Keio University
Physiological mechanism of sequential firing of hippocampal neurons during SW-RPrincipal Investigator
- Principal Investigator
  
  Ishikawa Tomoe
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biological pharmacy
- Research Institution
  Keio University

All 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Locally sequential synaptic reactivation during hippocampal ripples2020
- Author(s)
  Ishikawa Tomoe、Ikegaya Yuji
- Journal Title
  
  Science Advances
  
  Volume: 6 Issue: 7
- DOI
  10.1126/sciadv.aay1492
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16504
[Journal Article] Central Histamine Boosts Perirhinal Cortex Activity and Restores Forgotten Object Memories2019
- Author(s)
  Nomura H, Mizuta H, Norimoto H, Masuda F, Miura Y, Kubo A, Kojima H, Ashizuka A, Matsukawa N, Baraki Z, Hitora-Imamura N, Nakayama D, Ishikawa T, Okada M, Orita K, Saito R, Yamauchi N, Sano Y, Kusuhara H, Minami M, Takahashi H, Ikegaya Y
- Journal Title
  
  Biological Psychiatry
  
  Volume: 印刷中 Issue: 3 Pages: 230-239
- DOI
  10.1016/j.biopsych.2018.11.009
- NAID
  120006876277
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H05056, KAKENHI-PUBLICLY-18H05109, KAKENHI-PROJECT-17H07086, KAKENHI-PROJECT-17J10221, KAKENHI-PROJECT-16K06989, KAKENHI-PLANNED-18H05525
[Journal Article] Hippocampal ripples down-regulate synapses2018
- Author(s)
  Norimoto Hiroaki、Makino Kenichi、Gao Mengxuan、Shikano Yu、Okamoto Kazuki、Ishikawa Tomoe、Sasaki Takuya、Hioki Hiroyuki、Fujisawa Shigeyoshi、Ikegaya Yuji
- Journal Title
  
  Science
  
  Volume: 359 Issue: 6383 Pages: 1524-1527
- DOI
  10.1126/science.aao0702
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19451, KAKENHI-PUBLICLY-16H01426, KAKENHI-PUBLICLY-16H01519, KAKENHI-PLANNED-25119004, KAKENHI-PROJECT-26250003, KAKENHI-PROJECT-16H04663, KAKENHI-PROJECT-17H07086, KAKENHI-PROJECT-16J05301, KAKENHI-PROJECT-16J07503
[Journal Article] GABAergic inhibition reduces the impact of synaptic excitation on somatic excitation2018
- Author(s)
  Kobayashi Chiaki、Okamoto Kazuki、Mochizuki Yasuhiro、Urakubo Hidetoshi、Funayama Kenta、Ishikawa Tomoe、Kashima Tetsuhiko、Ouchi Ayako、Szymanska Agnieszka F.、Ishii Shin、Ikegaya Yuji
- Journal Title
  
  Neuroscience Research
  
  Volume: - Pages: 00-00
- DOI
  10.1016/j.neures.2018.09.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H07086, KAKENHI-PROJECT-16J07503, KAKENHI-PROJECT-18J14574, KAKENHI-PROJECT-17K00404
[Presentation] O17-MRIによる細胞性浮腫時の水動態の観察2021
- Author(s)
  石川智愛、星野豊、亀田浩之、小牧裕司、畝川美悠紀、冨田裕、中原仁、工藤與亮、安井正人
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K16504
[Presentation] Kinetics of O-17-labeled water in the brain parenchyma and cerebrospinal fluid of aquaporin-4-knockout mice on indirect MRI2020
- Author(s)
  Hoshino, Y., Kameda, H., Harada, T., Komaki, Y., Ishikawa, T., Yasui, M., and Kudo, K.
- Organizer
  ISMRM 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16504
[Presentation] Biphasic morphological and physiological responses, including the change of paravascular space2019
- Author(s)
  Ishikawa, T., Unekawa, M., Tomita, Y., Nakahara, J., Yasui, M.
- Organizer
  XIV European Meeting on Glial Cells in Health and Disease, GLIA 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16504
[Presentation] In vivo systemic reactions, including the morphological change of paravascular space, during water2019
- Author(s)
  Ishikawa, T., Unekawa, M., Tomita, Y., Nakahara, J., Yasui, M.
- Organizer
  BRAIN & BRAIN PET2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16504
[Presentation] Aquaporin 4 knockout in mice attenuates paravascular space closure and neuronal activity2019
- Author(s)
  Ishikawa, T., Unekawa, M., Tomita, Y., Nakahara, J., Yasui, M.
- Organizer
  Society for Neuroscience 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16504
[Presentation] 髄膜リンパ管が脳機能に与える影響の解明2019
- Author(s)
  松岡将司、満倉靖恵、石川智愛、安井正人
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17H07086
[Presentation] 水中毒が全身の生理パラメータおよびparavascular spaceに与える影響2018
- Author(s)
  石川智愛、畝川美悠紀、冨田裕、中原仁、安井正人
- Organizer
  先端モデル動物支援プラットフォーム若手支援技術講習会2018
- Data Source
  KAKENHI-PROJECT-17H07086
[Presentation] Water intoxication induces systemic reactions, including closure of paravascular space, in vivo.2018
- Author(s)
  Ishikawa, T., Unekawa, M., Tomita, Y., Nakahara, J., Yasui, M.
- Organizer
  6th International Conference on Glial Biology in Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07086
[Presentation] Real-time in vivo observation of the volume changes in astrocytes and perivascular spaces during water intoxication.2018
- Author(s)
  Ishikawa, T., Unekawa, M., Tomita, Y., Yasui, M.
- Organizer
  11th FENS Forum of Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07086
[Presentation] CA1 pyramidal neurons receive spatially clustered synaptic inputs during sharp waves/ripples EX vivo2017
- Author(s)
  Ishikawa, T., Ikegaya, Y.
- Organizer
  Society for Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07086
[Presentation] ヒスタミンH3受容体逆アゴニストは、思い出せなくなった物体記憶を回復させる2017
- Author(s)
  野村洋、水田弘人、乘本裕明、増田文貴、三浦友樹、小島寛人、芦塚あおい、松河理子、Zohal Baraki、人羅（今村）菜津子、中山大輔、石川智愛、齋藤瞭毅、佐野大和、楠原洋之、南雅文、高橋英彦、池谷裕二
- Organizer
  第39回日本生物学的精神医学会・第47回日本神経精神薬理学会合同年会
- Data Source
  KAKENHI-PROJECT-17H07086
[Presentation] Central histamine reactivates weak memory engrams and restores apparently forgotten object memories in mice and humans2017
- Author(s)
  Nomura, H., Mizuta, H., Norimoto, H., Masuda, F., Miura, Y., Kojima, H., Ashizuka, A., Matsukawa, N., Baraki, Z., Hitora-Imamura, N., Nakayama, D., Ishikawa, T., Saito, R., Sano, Y., Kusuhara, H., Minami, M., Takahashi, H., Ikegaya, Y.
- Organizer
  Society for Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07086
[Presentation] Sharp Wave発生時における空間的に局在したシナプス入力2017
- Author(s)
  石川智愛、池谷裕二
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17H07086

1. 日置寛之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 野村洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ishikawa Tomoe 石川 智愛

Research Projects

Research Products

Co-Researchers

Investigating the Development of Neuroimmune InteractionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of cognitive impairment after ligation of meningeal lymphatic vesselsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Physiological mechanism of sequential firing of hippocampal neurons during SW-RPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Locally sequential synaptic reactivation during hippocampal ripples2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Central Histamine Boosts Perirhinal Cortex Activity and Restores Forgotten Object Memories2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Hippocampal ripples down-regulate synapses2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] GABAergic inhibition reduces the impact of synaptic excitation on somatic excitation2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] O17-MRIによる細胞性浮腫時の水動態の観察2021

Author(s)

Organizer

Data Source

[Presentation] Kinetics of O-17-labeled water in the brain parenchyma and cerebrospinal fluid of aquaporin-4-knockout mice on indirect MRI2020

Author(s)

Organizer

Data Source

[Presentation] Biphasic morphological and physiological responses, including the change of paravascular space2019

Author(s)

Organizer

Data Source

[Presentation] In vivo systemic reactions, including the morphological change of paravascular space, during water2019

Author(s)

Organizer

Data Source

[Presentation] Aquaporin 4 knockout in mice attenuates paravascular space closure and neuronal activity2019

Author(s)

Organizer

Data Source

[Presentation] 髄膜リンパ管が脳機能に与える影響の解明2019

Author(s)

Organizer

Data Source

[Presentation] 水中毒が全身の生理パラメータおよびparavascular spaceに与える影響2018

Author(s)

Organizer

Data Source

[Presentation] Water intoxication induces systemic reactions, including closure of paravascular space, in vivo.2018

Author(s)

Organizer

Data Source

[Presentation] Real-time in vivo observation of the volume changes in astrocytes and perivascular spaces during water intoxication.2018

Author(s)

Organizer

Data Source

[Presentation] CA1 pyramidal neurons receive spatially clustered synaptic inputs during sharp waves/ripples EX vivo2017

Ishikawa Tomoe 石川智愛