Kato Takuma 加藤巧馬

Researcher Number	20805296
Other IDs	https://orcid.org/0000-0002-2561-8582
Affiliation (Current)	2024: 大阪医科薬科大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2018: 大阪薬科大学, 薬学部, 助教 2017: 大阪薬科大学, 薬学部, 助手(移行)
Review Section/Research Field	Principal Investigator Drug development chemistry
Keywords	Principal Investigator ドラッグデリバリーシステム / 有機化学 / 薬学 / 細胞膜透過性 / ヘリックス構造 / 膜透過性ペプチド / 二次構造解析 / ペプチド / 非天然型アミノ酸

Development of cell penetrating peptide utilizing the charactaristic of disubstituted amino acidPrincipal Investigator
- Principal Investigator
  
  Kato Takuma
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Drug development chemistry
- Research Institution
  Osaka University of Pharmaceutical Sciences

All 2019 2018 2017

All Journal Article Presentation

[Journal Article] Secondary structures and cell-penetrating abilities of arginine-rich peptide foldamers2019
- Author(s)
  Oba Makoto、Nagano Yu、Kato Takuma、Tanaka Masakazu
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 1349-1349
- DOI
  10.1038/s41598-018-38063-8
- NAID
  120006987810
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H07269, KAKENHI-PROJECT-17H03998
[Journal Article] Crystal structure of N-{N-[N-(tert-butoxycarbonyl)-L-α-aspartyl]-L-α-aspartyl}-L-α-aspartic acid 14,24,34-trimethyl ester 31-2-oxo-2-phenylethyl ester {Boc-[Asp(OMe)]3-OPac}2019
- Author(s)
  Kato Takuma、Kishimoto Saki、Asano Akiko、Doi Mitsunobu
- Journal Title
  
  Acta Crystallographica Section E Crystallographic Communications
  
  Volume: 75 Issue: 5 Pages: 585-588
- DOI
  10.1107/s2056989019004596
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H07269
[Journal Article] Left-handed helix of three-membered ring amino acid homopeptide interrupted by an N-H...ethereal O type hydrogen bond2018
- Author(s)
  Y. Koba, A. Ueda, M. Oba, M. Doi, T. Kato, Y. Demizu, M. Tanaka*
- Journal Title
  
  Org. Lett.
  
  Volume: 20 Issue: 24 Pages: 7830-7834
- DOI
  10.1021/acs.orglett.8b03331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08385, KAKENHI-PROJECT-18K14870, KAKENHI-PROJECT-17H03998, KAKENHI-PROJECT-17H07269, KAKENHI-PROJECT-16K18847
[Journal Article] Cell-Penetrating Peptides Using Cyclic α,α-Disubstituted α-Amino Acids with Basic Functional Groups2018
- Author(s)
  Kato Takuma、Oba Makoto、Nishida Koyo、Tanaka Masakazu
- Journal Title
  
  ACS Biomaterials Science & Engineering
  
  Volume: 4 Issue: 4 Pages: 1368-1376
- DOI
  10.1021/acsbiomaterials.8b00180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03998, KAKENHI-PROJECT-17H07269
[Journal Article] Enhanced and Prolonged Cell-Penetrating Abilities of Arginine-Rich Peptides by Introducing Cyclic α,α-Disubstituted α-Amino Acids with Stapling2017
- Author(s)
  Oba Makoto、Kunitake Masayuki、Kato Takuma、Ueda Atsushi、Tanaka Masakazu
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 28 Issue: 7 Pages: 1801-1806
- DOI
  10.1021/acs.bioconjchem.7b00190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18847, KAKENHI-PROJECT-17H07269
[Journal Article] Crystal structure of 3-(4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacen-3-yl)propanoic acid2017
- Author(s)
  Kato Takuma、Doi Mitsunobu
- Journal Title
  
  Acta Crystallographica Section E Crystallographic Communications
  
  Volume: 73 Issue: 12 Pages: 1974-1976
- DOI
  10.1107/s2056989017016942
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H07269
[Presentation] ヘリカルペプチドフォルダマーをキラル源とする不斉触媒反応の開発2019
- Author(s)
  梅野智大, 上田篤志, 加藤巧馬, 土井光暢, 田中正一
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17H07269
[Presentation] Aib含有ペプチドフォルダマーを用いたプラスミドDNAデリバリー2019
- Author(s)
  大庭誠, 伊藤有理香, 加藤巧馬, 田中正一
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17H07269
[Presentation] Design and Synthesis of Cyclic Disubstituted Amino Acids for Development of Cell Penetrating Peptide2018
- Author(s)
  Takuma Kato, Akiko Asano, Makoto Oba, Masakazu Tanaka, Mitsunobu Doi
- Organizer
  10th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07269
[Presentation] 膜透過性ペプチドへの応用のための環状ジ置換アミノ酸の合成2018
- Author(s)
  加藤巧馬、大庭　誠、田中正一、土井光暢
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H07269
[Presentation] 非天然型アミノ酸を含有するペプチドフォルダマーの二次構造と膜透過機能2018
- Author(s)
  大庭　誠, 永野優, 加藤巧馬, 田中正一
- Organizer
  日本ケミカルバイオロジー学会第13回年会
- Data Source
  KAKENHI-PROJECT-17H07269
[Presentation] Helical peptide-catalyzed asymmetric Michael addition reactions of malonates to cyclic enones2018
- Author(s)
  Tomohiro Umeno, Atsushi Ueda, Takuma Kato, Mitsunobu Doi, Masakazu Tanaka
- Organizer
  10th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07269
[Presentation] Synthesis of a Chiral Three-Membered Ring α,α-Disubstituted α-Amino Acid Having Two Methyl Groups and Conformational Analysis of its Peptides2018
- Author(s)
  Hikaru Ikeda, Atsushi Ueda, Makoto Oba, Takuma Kato, Mitsunobu Doi, Masakazu Tanaka
- Organizer
  10th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07269
[Presentation] Development and evaluation of cell-penetrating pe ptides having cyclic disubstituted amino acids2017
- Author(s)
  加藤巧馬、大庭　誠、田中正一
- Organizer
  第54回ペプチド討論会
- Data Source
  KAKENHI-PROJECT-17H07269
[Presentation] α,α-ジ置換アミノ酸を含有するペプチドの二次構造と膜透過機能の評価2017
- Author(s)
  大庭　誠、山澤翔太、國武正幸、江藤　諒、永野　優、伊藤有理香、加藤巧馬、田中正一
- Organizer
  日本ケミカルバイオロジー学会第12回年会
- Data Source
  KAKENHI-PROJECT-17H07269

1. Tanaka Masakazu (00227175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
2. Oba Makoto (20396716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. Doi Mitsunobu (10183500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. 出水庸介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 上田篤志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kato Takuma 加藤 巧馬

Research Projects

Research Products

Co-Researchers

Development of cell penetrating peptide utilizing the charactaristic of disubstituted amino acidPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Secondary structures and cell-penetrating abilities of arginine-rich peptide foldamers2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Crystal structure of N-{N-[N-(tert-butoxycarbonyl)-L-α-aspartyl]-L-α-aspartyl}-L-α-aspartic acid 14,24,34-trimethyl ester 31-2-oxo-2-phenylethyl ester {Boc-[Asp(OMe)]3-OPac}2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Left-handed helix of three-membered ring amino acid homopeptide interrupted by an N-H...ethereal O type hydrogen bond2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cell-Penetrating Peptides Using Cyclic α,α-Disubstituted α-Amino Acids with Basic Functional Groups2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enhanced and Prolonged Cell-Penetrating Abilities of Arginine-Rich Peptides by Introducing Cyclic α,α-Disubstituted α-Amino Acids with Stapling2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crystal structure of 3-(4,4-difluoro-5,7-dimethyl-4-bora-3a,4a-diaza-s-indacen-3-yl)propanoic acid2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] ヘリカルペプチドフォルダマーをキラル源とする不斉触媒反応の開発2019

Author(s)

Organizer

Data Source

[Presentation] Aib含有ペプチドフォルダマーを用いたプラスミドDNAデリバリー2019

Author(s)

Organizer

Data Source

[Presentation] Design and Synthesis of Cyclic Disubstituted Amino Acids for Development of Cell Penetrating Peptide2018

Author(s)

Organizer

Data Source

[Presentation] 膜透過性ペプチドへの応用のための環状ジ置換アミノ酸の合成2018

Author(s)

Organizer

Data Source

[Presentation] 非天然型アミノ酸を含有するペプチドフォルダマーの二次構造と膜透過機能2018

Author(s)

Organizer

Data Source

[Presentation] Helical peptide-catalyzed asymmetric Michael addition reactions of malonates to cyclic enones2018

Author(s)

Organizer

Data Source

[Presentation] Synthesis of a Chiral Three-Membered Ring α,α-Disubstituted α-Amino Acid Having Two Methyl Groups and Conformational Analysis of its Peptides2018

Author(s)

Organizer

Data Source

[Presentation] Development and evaluation of cell-penetrating pe ptides having cyclic disubstituted amino acids2017

Author(s)

Organizer

Data Source

[Presentation] α,α-ジ置換アミノ酸を含有するペプチドの二次構造と膜透過機能の評価2017

Author(s)

Organizer

Data Source

Kato Takuma 加藤巧馬