Terakawa Tsuyoshi 寺川剛

Researcher Number	20809652
Other IDs
Affiliation (Current)	2025: 京都大学, 理学研究科, 准教授
Affiliation (based on the past Project Information) *help	2024: 京都大学, 理学研究科, 准教授 2018 – 2022: 京都大学, 理学研究科, 助教
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (III) / Biological Sciences / Basic Section 43040:Biophysics-related / Complex systems / 0701:Biology at molecular to cellular levels, and related fields Except Principal Investigator Basic Section 43040:Biophysics-related
Keywords	Principal Investigator コンデンシン / 蛍光顕微鏡観察 / DNAカーテン / 一分子実験 / ヌクレオソーム / 分子モーター / 分子動力学シミュレーション / ヒストンリサイクリング / 染色体凝集 / 1分子蛍光顕微鏡観察 … More / 染色体 / ナノポアシーケンシング / エピゲノム継承 / ゲノム複製 / 染色体再構成 / 光ピンセット / 次世代シーケンシング / クロマチンカーテン / 一分子蛍光イメージング / DNAカーテン法 / 染色体ループ形成機構 / 粗視化分子動力学シミュレーション / １分子蛍光イメージング / ステップサイズ測定 / 銀ナノ粒子 / 金ナノ粒子 / 量子ドット / エピジェネティクス / クロマチン / ヒストン化学修飾 / 全反射蛍光顕微鏡 / 染色体凝縮 / 蛍光顕微鏡 … More Except Principal Investigator シナプス可塑性 / 転写制御 / 液液相分離 / 生体分子凝縮体 Less

細胞内複雑環境下の相分離による生体分子凝縮体形成の生物物理
- Principal Investigator
  
  高田彰二
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Kyoto University
Molecule- and cell-scale bridging approach to epigenome inheritanceArea Organizer
- Area Organizer
  
  寺川剛
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
エピゲノム継承への分子・細胞スケールブリッジアプローチの推進Principal Investigator
- Principal Investigator
  
  寺川剛
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyoto University
ナノポア解析と分子シミュレーションで探るヒストンリサイクリングの鎖バイアス機構Principal Investigator
- Principal Investigator
  
  寺川剛
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyoto University
クロマチンカーテン法によるクロマチン凝集の1分子蛍光顕微鏡観察Principal Investigator
- Principal Investigator
  
  寺川剛
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
DNAカーテン測定によるヒストン化学修飾がクロマチン凝集に与える影響の解明Principal Investigator
- Principal Investigator
  
  寺川剛
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
金銀・ナノ粒子を用いたコンデンシン分子モーターの超高分解能DNAカーテン測定Principal Investigator
- Principal Investigator
  
  寺川剛
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto University
Molecular mechanisms of a Condensin molecular motor explored by DNA curtain assays and coarse-grained molecular dynamics simulationsPrincipal Investigator
- Principal Investigator
  
  Terakawa Tsuyoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Kyoto University
Elucidation of the molecular mechanism of chromatin folding by single molecule experimentsPrincipal Investigator
- Principal Investigator
  
  寺川剛
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0701:Biology at molecular to cellular levels, and related fields
- Research Institution
  Kyoto University

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] ALS mutations in the TIA-1 prion-like domain trigger highly condensed pathogenic structures2022
- Author(s)
  Sekiyama Naotaka、Takaba Kiyofumi、Maki-Yonekura Saori、Akagi Ken-ichi、Ohtani Yasuko、Imamura Kayo、Terakawa Tsuyoshi、Yamashita Keitaro、Inaoka Daigo、Yonekura Koji、Kodama Takashi S.、Tochio Hidehito
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 38
- DOI
  10.1073/pnas.2122523119
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21H00252, KAKENHI-PLANNED-22H05090
[Journal Article] Coarse-grained molecular dynamics simulations of base-pair mismatch recognition protein MutS sliding along DNA2022
- Author(s)
  Inoue Keisuke、Takada Shoji、Terakawa Tsuyoshi
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 19 Issue: 0 Pages: n/a
- DOI
  10.2142/biophysico.bppb-v19.0015
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H00252, KAKENHI-PLANNED-20H05934, KAKENHI-PROJECT-21H02441
[Journal Article] Modeling of DNA binding to the condensin hinge domain using molecular dynamics simulations guided by atomic force microscopy2021
- Author(s)
  Koide Hiroki、Kodera Noriyuki、Bisht Shveta、Takada Shoji、Terakawa Tsuyoshi
- Journal Title
  
  PLOS Computational Biology
  
  Volume: 17 Issue: 7 Pages: e1009265-e1009265
- DOI
  10.1371/journal.pcbi.1009265
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H00252, KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-19H03194, KAKENHI-PLANNED-20H05934
[Journal Article] Single-molecule junction spontaneously restored by DNA zipper2021
- Author(s)
  Harashima Takanori、Fujii Shintaro、Jono Yuki、Terakawa Tsuyoshi、Kurita Noriyuki、Kaneko Satoshi、Kiguchi Manabu、Nishino Tomoaki
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 5762-5762
- DOI
  10.1038/s41467-021-25943-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H00252, KAKENHI-PROJECT-19H03194, KAKENHI-PROJECT-19J20605, KAKENHI-PROJECT-20K05445, KAKENHI-PROJECT-23K21124
[Journal Article] The lane-switch mechanism for nucleosome repositioning by DNA translocase2021
- Author(s)
  Nagae Fritz、Brandani Giovanni B、Takada Shoji、Terakawa Tsuyoshi
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 49 Issue: 16 Pages: 9066-9076
- DOI
  10.1093/nar/gkab664
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21H00252, KAKENHI-PROJECT-19H03194, KAKENHI-PLANNED-20H05934
[Presentation] Molecular mechanism of H2A/H2B dismantling from a partially unwrapped nucleosome by Nap12023
- Author(s)
  Fritz Nagae, Shoji Takada, Tsuyoshi Terakawa
- Organizer
  66th Biophysical Society Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H00252
[Presentation] Nap1 dismantles a H2A/H2B dimer from a partially unwrapped nucleosome2022
- Author(s)
  Fritz Nagae, Shoji Takada, Tsuyoshi Terakawa
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00252
[Presentation] トランスロケースとの衝突に伴うヌクレオソームの運命: エピゲノム継承の解明に向けて2022
- Author(s)
  寺川剛
- Organizer
  第15回エピジェネティクス研究会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00252
[Presentation] Molecular dynamics simulations to reveal molecular mechanism of DNA stimulated ATPase activity of SMC proteins2022
- Author(s)
  Masataka Yamauchi, Tsuyoshi Terakawa, Giovanni B. Brandani, and Shoji Takada
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00252
[Presentation] Molecular mechanism of epigenetic inheritance in single-molecule level2022
- Author(s)
  寺川剛
- Organizer
  さきがけ「ゲノムスケールのDNA設計・合成による細胞制御技術の創出」第２回単独領域会議
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00252
[Presentation] DNA curtain assays of collisions between Condensin and Nucleosome2022
- Author(s)
  寺川剛
- Organizer
  新学術領域「クロマチン潜在能」領域会議
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00252
[Presentation] DNA binding affinity of human cohesin subunits participating in loop-extrusion mechanism studied by molecular dynamics simulation2022
- Author(s)
  Chenyang Gu, Giovanni Brandani, Tsuyoshi Terakawa, Shoji Takada
- Organizer
  第22回日本蛋白質科学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00252
[Presentation] Structural modeling of condensin by assimilating high-speed atomic force microscopy images2022
- Author(s)
  Hiroki Koide, Noriyuki Kodera ,Mayu S. Terakawa, Shoji Takada, Tsuyoshi Terakawa
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00252
[Presentation] Molecular mechanisms of epigenetic inheritance in single-molecule level2022
- Author(s)
  寺川剛
- Organizer
  さきがけ「ゲノムスケールのDNA設計・合成による細胞制御技術の創出」第２回単独領域会議
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00252
[Presentation] Single molecule imaging of DNA unwinding by budding yeast Mcm2-72022
- Author(s)
  Mayu S. Terakawa, Tsuyoshi Terakawa
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00252
[Presentation] Molecular dynamics simulations of the yeast condensin holo complex towards elucidation of the mechanism of DNA loop extrusion2021
- Author(s)
  Hiiroki Koide、 Shoji Takada、 Tsuyoshi Terakawa
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00252
[Presentation] Molecular mechanism of MutS sliding on DNA explored by coarse-grained molecular dynamics simulations2021
- Author(s)
  Keisuke Inoue、Shoji Takada、Tsuyoshi Terakawa
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19H03194
[Presentation] Evaluation of DNA binding of yeast replisome toward single-molecule observation of DNA replication2021
- Author(s)
  Mayu S. Terakawa、Tsuyoshi Terakawa
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19H03194
[Presentation] The lane switch mechanism: Nucleosome repositioning induced by a DNA translocase2021
- Author(s)
  Fritz Nagae、Giovanni B. Brandani、Shoji Takada、Tsuyoshi Terakawa
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19H03194
[Presentation] Evaluation of DNA binding of yeast replisome toward single-molecule observation of DNA replication2021
- Author(s)
  Mayu S. Terakawa、 Tsuyoshi Terakawa
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00252
[Presentation] DNA translocase repositions a nucleosome by the lane-switch mechanism2021
- Author(s)
  Fritz Nagae、Giovanni B. Brandani、Shoji Takada、Tsuyoshi Terakawa
- Organizer
  20th IUPAB Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03194
[Presentation] Nucleosome repositioning dynamics upon collision with a translocase2021
- Author(s)
  Tsuyoshi Terakawa
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03194
[Presentation] The lane switch mechanism: Nucleosome repositioning induced by a DNA translocase2021
- Author(s)
  Fritz Nagae、 Giovanni B. Brandani、 Shoji Takada、 Tsuyoshi Terakawa
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00252
[Presentation] Molecular mechanism of MutS sliding on DNA explored by coarse-grained molecular dynamics simulations2021
- Author(s)
  Keisuke Inoue、 Shoji Takada、 Tsuyoshi Terakawa
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00252
[Presentation] DNA translocase repositions a nucleosome by the lane-switch mechanism2021
- Author(s)
  Fritz Nagae、 Giovanni B. Brandani、 Shoji Takada、 Tsuyoshi Terakawa
- Organizer
  20th IUPAB Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H00252
[Presentation] Nucleosome repositioning dynamics upon collision with a translocase2021
- Author(s)
  Tsuyoshi Terakawa
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H00252
[Presentation] Molecular dynamics simulations of the yeast condensin holo complex towards elucidation of the mechanism of DNA loop extrusion2021
- Author(s)
  Hiiroki Koide、Shoji Takada、Tsuyoshi Terakawa
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-19H03194
[Presentation] Reconstitution of protein functions on chromatin curtain2020
- Author(s)
  寺川剛
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05260
[Presentation] Reconstitution of protein functions on chromatin curtain2020
- Author(s)
  寺川剛
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05392
[Presentation] Reconstitution of protein functions on chromatin curtain2020
- Author(s)
  寺川剛
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03194
[Presentation] DNA curtains: high-throughput single molecule imaging for DNA transactions2019
- Author(s)
  寺川剛
- Organizer
  第57回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05260
[Presentation] Single-molecule observation of chromatin condensation induced by Condensin molecular motor2019
- Author(s)
  寺川剛
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05392
[Presentation] Single-molecule observation of chromatin condensation induced by Condensin molecular motor2019
- Author(s)
  寺川剛
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05260
[Presentation] 染色体凝集の分子基盤: コンデンシン分子モーターの分子観察2019
- Author(s)
  寺川　剛
- Organizer
  国立遺伝学研究所研究集会「ゲノムの維持継承を支える分子基盤の包括的理解とその発展」
- Invited
- Data Source
  KAKENHI-PROJECT-18H06046
[Presentation] DNA curtains: high-throughput single molecule imaging for DNA transactions2019
- Author(s)
  寺川剛
- Organizer
  第57回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-19H05392
[Presentation] DNA上の新しい分子モーター: コンデンシン2018
- Author(s)
  寺川　剛
- Organizer
  分子モーター討論会
- Invited
- Data Source
  KAKENHI-PROJECT-18H06046
[Presentation] コンデンシン複合体は分子モーターである2018
- Author(s)
  寺川　剛
- Organizer
  第56回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H06046
[Presentation] The condensin complex is a new type of DNA molecular motor2018
- Author(s)
  寺川　剛
- Organizer
  第79回岡崎コンファレンス
- Invited
- Data Source
  KAKENHI-PROJECT-18H06046

1. 高田彰二 (60304086)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 日詰光治 (10378846)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 三浦尚 (10639082)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 角南智子 (50554648)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Terakawa Tsuyoshi 寺川 剛

Research Projects

Research Products

Co-Researchers

細胞内複雑環境下の相分離による生体分子凝縮体形成の生物物理

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecule- and cell-scale bridging approach to epigenome inheritanceArea Organizer

Area Organizer

Project Period (FY)

Research Category

エピゲノム継承への分子・細胞スケールブリッジアプローチの推進Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ナノポア解析と分子シミュレーションで探るヒストンリサイクリングの鎖バイアス機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

クロマチンカーテン法によるクロマチン凝集の1分子蛍光顕微鏡観察Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

DNAカーテン測定によるヒストン化学修飾がクロマチン凝集に与える影響の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

金銀・ナノ粒子を用いたコンデンシン分子モーターの超高分解能DNAカーテン測定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of a Condensin molecular motor explored by DNA curtain assays and coarse-grained molecular dynamics simulationsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular mechanism of chromatin folding by single molecule experimentsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] ALS mutations in the TIA-1 prion-like domain trigger highly condensed pathogenic structures2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Coarse-grained molecular dynamics simulations of base-pair mismatch recognition protein MutS sliding along DNA2022

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Modeling of DNA binding to the condensin hinge domain using molecular dynamics simulations guided by atomic force microscopy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single-molecule junction spontaneously restored by DNA zipper2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The lane-switch mechanism for nucleosome repositioning by DNA translocase2021

Author(s)

Terakawa Tsuyoshi 寺川剛