Amano Ryo 天野亮

Researcher Number	20818687
Other IDs
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立感染症研究所次世代生物学的製剤研究センター, 主任研究員
Affiliation (based on the past Project Information) *help	2025: 東京大学, 医科学研究所, 特任研究員 2020 – 2023: 東京大学, 医科学研究所, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
Keywords	Principal Investigator 核酸抗体 / RNAアプタマー / 脳内薬剤送達用キャリア / トランスフェリン受容体 / インスリン受容体 / マルチプレックスSELEX / 表面プラズモン共鳴（SPR）法 / 脳 / DDS / トランスフェリン受容体（TfR） … More / インスリン受容体（IR) / Multiplex SELEX / 表面プラズモン共鳴(SPR)法 / マルチプレックス化 / トランスフェリン受容体（TfR) / インスリン受容体（IR） / 脳内薬剤送達（DDS) / 核酸医薬 / Multiplex SELEX法 / VLP / SELEX法 / 中和分子 / デングウイルス / Virus-like particle / ウイルス様粒子 / SELEX Less

VLP-SELEX法を活用したウイルス結合分子創製法への電気泳動選別技術の導入と検証Principal Investigator
- Principal Investigator
  
  天野亮
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  The University of Tokyo
Multiplex SELEX-based selection strategy to generate multifunctional aptamers targeting the transferrin receptor (TfR) and the insulin receptor (IR).Principal Investigator
- Principal Investigator
  
  Amano Ryo
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  The University of Tokyo
RNA aptamers targeting dengue virusPrincipal Investigator
- Principal Investigator
  
  Amano Ryo
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020

All Journal Article Presentation Patent

[Journal Article] Selection of aptamers using β-1,3-glucan recognition protein-tagged proteins and curdlan beads2023
- Author(s)
  Kumagai Kazuyuki、Okubo Hiroki、Amano Ryo、Kozu Tomoko、Ochiai Masanori、Horiuchi Masataka、Sakamoto Taiichi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 174 Issue: 5 Pages: 433-440
- DOI
  10.1093/jb/mvad059
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10046, KAKENHI-PROJECT-22K05939, KAKENHI-PROJECT-20K06529, KAKENHI-PROJECT-21K12129, KAKENHI-PROJECT-22K14789
[Journal Article] Specific Inhibition of FGF5-induced Cell Proliferation by RNA Aptamers2021
- Author(s)
  Amano, R., Namekata, M., Horiuchi, M., Saso, M., Yanagisawa, T., Tanaka, Y., Ghani, F.I., Yamamoto, M., Sakamoto T.
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 2976-2976
- DOI
  10.1038/s41598-021-82350-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06529, KAKENHI-PROJECT-20K15406, KAKENHI-PROJECT-17K05936, KAKENHI-PROJECT-18K11536
[Journal Article] Nucleic acid ligands act as a PAM and agonist depending on the intrinsic ligand binding state of P2RY22021
- Author(s)
  Takahashi Masaki、Amano Ryo、Ozawa Michiru、Martinez Anna、Akita Kazumasa、Nakamura Yoshikazu
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 118 Issue: 18
- DOI
  10.1073/pnas.2019497118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21880, KAKENHI-PROJECT-20K15406
[Patent] アデノ随伴ウイルスセロタイプ9に対するアプタマー及びその使用2024
- Inventor(s)
  高橋理貴、天野亮、中村義一
- Industrial Property Rights Holder
  高橋理貴、天野亮、中村義一
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-040542
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-22K14789
[Presentation] VLP-SELEXとin silico解析によるデングウイルス中和アプタマーの創製と有効性評価2023
- Author(s)
  天野亮、道下瑛陽、中野涼太、一ノ瀬顕子、芳賀和美、Meng Ling Moi、浜田道昭、中村義一、高橋理貴
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K14789
[Presentation] Generation of an RNA aptamer neutralizing dengue viruses by SELEX method targeting virus-like particles and advanced in silico analyses.2023
- Author(s)
  Ryo Amano, Akiya Michishita, Ryota Nakano, Akiko Ichinose, Kazumi Haga, Meng Ling Moi, Michiaki Hamada, Yoshikazu Nakamura, Masaki Takahashi
- Organizer
  INSNAC2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K14789
[Presentation] Multi-VLP SELEXとin silico解析によるデングウイルス中和アプタマーの創製戦略2022
- Author(s)
  天野亮, 道下瑛陽, 中野涼太,一ノ瀬顕子, 浜田道昭, 中村義一, 高橋理貴
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K14789
[Presentation] ウイルス様粒子とMultiplex SELEXを用いたデングウイルス中和アプタマーの創製2021
- Author(s)
  天野亮 , 一ノ瀬顕子 , 浜田道昭 , 中村義一 , 高橋理貴
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K15406
[Presentation] ウイルス様粒子とin silico解析を用いたデングウイルス中和アプタマーの創製2020
- Author(s)
  天野亮、一ノ瀬顕子、浜田道昭、中村義一、高橋理貴
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K15406

1. SAKAMOTO Taiichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. HORIUCHI Rumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. TAKAHASHI Masaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 堀内正隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Amano Ryo 天野 亮

Research Projects

Research Products

Co-Researchers

VLP-SELEX法を活用したウイルス結合分子創製法への電気泳動選別技術の導入と検証Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Multiplex SELEX-based selection strategy to generate multifunctional aptamers targeting the transferrin receptor (TfR) and the insulin receptor (IR).Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

RNA aptamers targeting dengue virusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Selection of aptamers using β-1,3-glucan recognition protein-tagged proteins and curdlan beads2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Specific Inhibition of FGF5-induced Cell Proliferation by RNA Aptamers2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nucleic acid ligands act as a PAM and agonist depending on the intrinsic ligand binding state of P2RY22021

Author(s)

Journal Title

DOI

Data Source

[Patent] アデノ随伴ウイルスセロタイプ9に対するアプタマー及びその使用2024

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Presentation] VLP-SELEXとin silico解析によるデングウイルス中和アプタマーの創製と有効性評価2023

Author(s)

Organizer

Data Source

[Presentation] Generation of an RNA aptamer neutralizing dengue viruses by SELEX method targeting virus-like particles and advanced in silico analyses.2023

Author(s)

Organizer

Data Source

[Presentation] Multi-VLP SELEXとin silico解析によるデングウイルス中和アプタマーの創製戦略2022

Author(s)

Organizer

Data Source

[Presentation] ウイルス様粒子とMultiplex SELEXを用いたデングウイルス中和アプタマーの創製2021

Author(s)

Organizer

Data Source

[Presentation] ウイルス様粒子とin silico解析を用いたデングウイルス中和アプタマーの創製2020

Author(s)

Organizer

Data Source

Amano Ryo 天野亮