Uehara Hirofumi 上原博史

Researcher Number	20822555
Other IDs
Affiliation (based on the past Project Information) *help	2021 – 2023: 大阪医科薬科大学, 医学部, 准教授 2019 – 2020: 大阪医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related Except Principal Investigator Basic Section 56030:Urology-related
Keywords	Principal Investigator BNN / 免疫療法 / CD4Tcell / T細胞 / マウス / BBN / NAD＋ / 免疫賦活 / 膀胱癌 / BCG / NAD+ … More Except Principal Investigator … More BNCT / BOAI / 浸潤癌 / 膀胱温存 Less

Therapeutic effect of boron neutron supplementation therapy with PDL1 antibody for advanced bladder cancer (including metastasis)
- Principal Investigator
  
  東治人
- Project Period (FY)
  2021 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Studies on a novel immunotherapy for bladder cancer by NAD+Principal Investigator
- Principal Investigator
  
  Uehara Hirofumi
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka Medical and Pharmaceutical University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Importance of Management of Lifestyle-Related Diseases After Kidney Donation to Living Donors2024
- Author(s)
  Hirano H,Fujiwara Y,Okabe T, Nakamori K,Minami K,Uehara H, Nomi H,Komura K,Inamoto T, Azuma H.
- Journal Title
  
  Transplantation Proceedings
  
  Volume: 56 Issue: 3 Pages: 479-81
- DOI
  10.1016/j.transproceed.2024.01.027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09386
[Journal Article] Usefulness of Dietary Salt Restriction in Kidney Transplant Recipients: Analysis of Blood Pressure Levels Depending on the Differences in the Levels of Salt Intake2023
- Author(s)
  Hirano H,Fujiwara Y, Maenosono R,Minami K,Uehara H,Okabe T, Nakamori K,Nomi H,Komura K, Inamoto T,Azuma H.
- Journal Title
  
  Transplantation Proceedings
  
  Volume: 55 Issue: 4 Pages: 841-4
- DOI
  10.1016/j.transproceed.2023.03.054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09386
[Journal Article] Tissue Distribution of Cisplatin by Intra-arterial Infusion Route in Comparison to Systemic Route: Implication to Therapy for Node-positive Bladder Cancer2023
- Author(s)
  ICHIHASI A、INAMOTO T、UCHIMOTO T、NAKAMURA K、KOMURA K、YANO Y、NISHIMURA K、KINOSHITA S、NISHIO K、FUKUSHIMA T、NAKAMORI K、MATSUNAGA T、TSUTSUMI T、TSUJINO T、UEHARA H、TAKAHARA K、YAMAMOTO K、KATO R、IJIRI Y、HAYASHI T、AZUMA H.
- Journal Title
  
  In Vivo
  
  Volume: 37 Issue: 1 Pages: 143-148
- DOI
  10.21873/invivo.13063
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09702, KAKENHI-PROJECT-21K09386
[Journal Article] Nephron-sparing ureteroscopic surgery vs. radical nephroureterectomy: comparable survival-outcomes in upper tract urothelial carcinoma2023
- Author(s)
  Tsujino T,Komura K,Inamoto T,Maenosono R,Hashimoto T, Adachi T, Hirasawa Y,Tokushige S,Ohno T,Yamazaki S,Fukushima T,Nakamura K,Yano Y,Nishimura K,Kinoshita S,Nakamori K,Tsutsumi T,Matsunaga T,Yoshikawa Y,Uchimoto T,Takai T,Minami K,Uehara H,Hirano H,Nomi H,Takaraha K,Ohno Y,Azuma H.
- Journal Title
  
  World Journal of Urology
  
  Volume: 41 Issue: 12 Pages: 3585-91
- DOI
  10.1007/s00345-023-04687-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09386, KAKENHI-PROJECT-22K09512, KAKENHI-PROJECT-19K09702
[Journal Article] Pattern of expression of microRNA in patients with radiation induced bladder injury2023
- Author(s)
  Nakamura Ko、Ohno Takaya、Inamoto Teruo、Takai Tomoaki、Uchimoto Taizo、Fukushima Tatsuo、Nishimura Kazuki、Yano Yusuke、Nishio Kyosuke、Kinoshita Shoko、Matsunaga Tomohisa、Nakamori Keita、Tsutsumi Takeshi、Tsujino Takuya、Uehara Hirofumi、Komura Kazumasa、Takahara Kiyoshi、Azuma Haruhito
- Journal Title
  
  Oncology
  
  Volume: ー Issue: 7 Pages: 585-592
- DOI
  10.1159/000535993
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09702
[Journal Article] Optimal Time Point for Evaluation of Response to Pembrolizumab Treatment in Japanese Patients With Metastatic Urothelial Carcinoma2023
- Author(s)
  Inamoto T,Sato R,Matsushita Y,Uchimoto T,Nakamuran K.O, Komura K , Nishimura N,Yano Y, Nishio K,Kinoshita S,Fukushima T,Matsunaga T, Nakamori K,Tsutsumi T,Tsujino T,Uehara H,Takahara K, Miyake H,Azuma H.
- Journal Title
  
  Cancer Diagnosis & Prognosis
  
  Volume: 3 Issue: 3 Pages: 370-6
- DOI
  10.21873/cdp.10226
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09386, KAKENHI-PROJECT-19K09702
[Journal Article] Efficacy of pembrolizumab and comprehensive CD274/PD-L1 profiles in patients previously treated with chemoradiation therapy as radical treatment in bladder cancer2022
- Author(s)
  Nishimura ｋ, Nishio K, Hirosuna K,Komura K, Hayashi T,Fukuokaya W, Ura A,Uchimoto T, Nakamura K, Fukushima T,Yano Y,Takahashi N, Nakamori K, Kinoshita S,Matsunaga T, Tsutsumi T,Tsujino T,Taniguchi K,Tanaka T,Uehara H, Takahara K,Inamoto T,Hirose Y,Kimura T,Egawa S,Azuma H.
- Journal Title
  
  Journal for ImmunoTherapy of Cancer
  
  Volume: 10 Issue: 1 Pages: e003868-e003868
- DOI
  10.1136/jitc-2021-003868
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09386, KAKENHI-PROJECT-23K21471
[Journal Article] Prognostic value of the fluctuation in the neutrophil lymphocyte ratio at 6 weeks of pembrolizumab treatment is specific to the clinical response in metastatic urothelial carcinoma.2022
- Author(s)
  Uchimoto T,Nakamura K, Komura K, Fukuokaya W, Yano Y, Nishimura K, Kinoshita S, Nishio K, Fukushima T, Nakamori K, Matsunaga T, Tsutsumi T, Tsujino T, Taniguchi K, Tanaka T, Uehara H, Takahara K, Inamoto T, Kimura T, Egawa S, Azuma H.
- Journal Title
  
  Urologic oncology
  
  Volume: 40 Issue: 7 Pages: 11-17
- DOI
  10.1016/j.urolonc.2022.02.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09386, KAKENHI-PROJECT-23K21471
[Journal Article] Unplanned hemodialysis initiation and low geriatric nutritional risk index scores are associated with end-stage renal disease outcomes.2022
- Author(s)
  Maenosono R,Fukushima T, Kobayashi D, Matsunaga T, Yano Y, Taniguchi S, Fujiwara Y, Komura K, Uehara H, Kagitani M, Hirano H, Inamoto T, Nomi H, Azuma H.
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 11101-11101
- DOI
  10.1038/s41598-022-14123-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09386
[Journal Article] Increased BUB1B/BUBR1 expression contributes to aberrant DNA repair activity leading to resistance to DNA-damaging agents2021
- Author(s)
  Komura Kazumasa、Inamoto Teruo、Tsujino Takuya、Matsui Yusuke et al.
- Journal Title
  
  Oncogene
  
  Volume: 40 Issue: 43 Pages: 6210-6222
- DOI
  10.1038/s41388-021-02021-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K18151, KAKENHI-PROJECT-18H03207, KAKENHI-PROJECT-21K09386, KAKENHI-PROJECT-23K20389
[Journal Article] Hemodialysis Initiation in Oldest-Old Patients: A Case Series.2021
- Author(s)
  Maenosono R,Matsunaga T,Yoshikawa Y,Nishimura K,Onaka H, Komura K, Uehara H,Azuma H.
- Journal Title
  
  Case Rep Nephrol Dial
  
  Volume: 11 Issue: 3 Pages: 286-91
- DOI
  10.1159/000518706
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09386
[Journal Article] Taurodeoxycholic acid and valine reverse obesity-associated augmented alloimmune responses and prolong allograft survival.2021
- Author(s)
  Quante M, Iske J, Uehara H, Minami K, Nian Y, Maenosono R, Matsunaga T, Liu Y, Azuma H, Perkins D, Alegre ML, Zhou H, Elkhal A, Tullius SG.
- Journal Title
  
  American Journal of Transplantation
  
  Volume: 22 Issue: 2 Pages: 402-13
- DOI
  10.1111/ajt.16856
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09702, KAKENHI-PROJECT-21K09386
[Journal Article] Risk Classification for Overall Survival by the Neutrophil-Lymphocyte Ratio and the Number of Metastatic Sites in Patients Treated with Pembrolizumab-A Multicenter Collaborative Study in Japan.2021
- Author(s)
  Uchimoto T,Komura K,Fukuokaya W, Kimura T,Takahashi K, Yano Y, Nishimura K Nakamori K,Fujiwara Y,Matsunaga T,Tsutsumi T,Tsujino T, Maenosono R,Yoshikawa Y,Taniguchi K,Tanaka T,Uehara H, Hirano H,Nomi H,Takahara K,Inamoto T,Egawa S, Azuma H.
- Journal Title
  
  Cancers
  
  Volume: 13(14)3554 Issue: 14 Pages: 1-10
- DOI
  10.3390/cancers13143554
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09386
[Journal Article] 筋層浸潤性膀胱癌に対する新規治療戦略：膀胱温存療法のさらなる発展に向けて2021
- Author(s)
  東　治人,小村和正、上原博史、新保大樹、山本和宏、稲元輝生.
- Journal Title
  
  泌尿器外科
  
  Volume: 34（11） Pages: 1245-56
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09386
[Journal Article] Targeting of intragraft reactive oxygen species by APP-103, a novel polymer product, mitigates ischemia/reperfusion injury and promotes the survival of renal transplants.2020
- Author(s)
  Minami K, Bae S, Uehara H, Zhao C, Lee D, Iske J, Fanger MW, Reder J, Morrison I, Azuma H, Wiens A, Van Keuren E, Houser B, ElKhal A, Kang PM, Tullius SG.
- Journal Title
  
  Am J Transplant.
  
  Volume: - Issue: 6 Pages: 1527-37
- DOI
  10.1111/ajt.15794
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09702, KAKENHI-PROJECT-16K11033
[Journal Article] Management of alpha-herpesvirus infection following kidney transplantation: Our experience (7 cases)2020
- Author(s)
  Hirofumi Uehara, Hajime Hirano, Tomohisa Matsunaga, Koichiro Minami, Kazumasa Komura, Naokazu Ibuki, Teruo Inamoto, Hayahito Nomi, Haruhito Azuma
- Journal Title
  
  Transplantation Reports
  
  Volume: Volume 5, Issue 3, September, Issue: 3 Pages: 100051-100051
- DOI
  10.1016/j.tpr.2020.100051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09702
[Presentation] The association between outcome and malnutrition score in hemodialysis associated renal cancer patients.2023
- Author(s)
  Maenosono R,Okabe T,Shinmyo T, Hanamori T, Goji K,Tsujino T, Uehara H,Komura K,Hirano H, Nomi H,Inamoto T,Azuma H.
- Organizer
  AOS2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] Management of alpha-herpesvirus infection following kidney transplantation: Our experience (14 cases)2023
- Author(s)
  Uehara H,Hirano H, Matsunaga T,Minami K,Komura K,Ibuki N, Inamoto T,Nomi H,Azuma H.
- Organizer
  第100回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] 限局性膀胱癌に対する膀胱温存療法の年齢層別解析.2023
- Author(s)
  稲元輝生、辻野拓也、前之園良一、西村一希、中村公、大野貴也、髙井朋聡、小村和正、上原博史、平野一、能見勇人、東治人.
- Organizer
  第73回日本泌尿器科学会中部総会
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] Correlation between genetic alterations fibroblast growth factor recepters and immune-microenvironment profiles in bladder cancer.2023
- Author(s)
  Nishimur K,Komura K,Hirosuna K,Hayashi T,Ura A,Tsujino T,Uchimoto T,Minami K,Uehara H,Inamoto T,Yoshimi A, Azuma H.
- Organizer
  第110回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] Importance of management of lifestyle-related diseases after kidney donation to living donors.2023
- Author(s)
  Hirano H,Fujiwara Y, Okabe T,Nakamori K, Maenosono R, Minami K,Uehara H, Nomi H,Komura K,Inamoto, Azuma H.
- Organizer
  CAST2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] 膀胱癌診療における超音波検査の有用性2022
- Author(s)
  上原博史, 田中恵美子, 本村友希, 辻野拓也 ,南幸一郎, 小村和正,平野一, 稲元輝生, 能見勇人, 東治人.
- Organizer
  日本超音波医学会第95回学術集会
- Data Source
  KAKENHI-PROJECT-19K09702
[Presentation] Occurrence of Malignant Tumors in Post-Renal Transplant Patients at Our Hospital2022
- Author(s)
  Minami K,Hirano H, Uehara H,Komura　K, Maenosono R,Fujiwara Y,Okabe T, Nakamori K,Inamoto T,Nomi H, Azuma H.
- Organizer
  2022　TSS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] 上部尿路腫瘍に対する臓器温存の経験と生検病理組織の解析2022
- Author(s)
  稲元輝生、中森啓太、徳永雄希、前之園　良一、辻野拓也、南　幸一郎、小村和正、上原博史、能見勇人、東　治人.
- Organizer
  第43回日本レーザー医学会総会
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] HoとNdによるUTUC治療と成績2022
- Author(s)
  稲元輝生、中森啓太、徳永雄希、前之園　良一、辻野拓也、南　幸一郎、小村和正、上原博史、能見勇人、東　治人.
- Organizer
  第36回日本泌尿器内視鏡・ロボティクス学会総会
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] 当院における腎移植後患者における悪性腫瘍発生について2022
- Author(s)
  南　幸一郎,岡部知太,前之園良一,藤原裕也,中森啓太,上原博史,平野一,能見勇人,東治人 .
- Organizer
  第58回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] Usefulness Of Dietary Salt Restriction In Kidney Transplant Recipients: Analysis Of Blood Pressure Levels Depending On The Differences In The Levels Of Salt Intake2022
- Author(s)
  Hirano H,Fujiwara　Y, Maenosono　R,Minami　K,Uehara　H,Okabe　T,Nakamori　K, Nomi　H,Komura　K,Inamoto　T, Azuma　H.
- Organizer
  2022　TSS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] 当院での生体腎移植後患者における、新型コロナウイルスワクチンの有用性2022
- Author(s)
  岡部知太,平野　一, 前之園　良一,中森啓太, 藤原裕也,南　幸一郎, 上原博史, 能見勇人,稲元輝生, 東　治人.
- Organizer
  第58回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] 根治的化学放射線療法後の転移性膀胱癌におけるPembrolizumab有効性/包括的PD-L1解析.2022
- Author(s)
  西村一希,小村和正,木村高弘,林大久夫,内本泰三,福岡屋航,浦礼子,上原博史,平野一,稲元輝生,能見勇人,廣瀬善信,穎川晋,東治人.
- Organizer
  第60回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09386
[Presentation] 生体腎移植前のドナー検査において腫瘍性病変が指摘され、根治的治療が可能であった3症例2020
- Author(s)
  上原博史,堤岳之,小村和正,伊夫貴直和,稲元輝生,能見勇人,東治人.
- Organizer
  第53回日本臨床腎移植学会
- Data Source
  KAKENHI-PROJECT-19K09702
[Presentation] 当施設における腎細胞癌に対するpresurgical therapyの臨床的検討2020
- Author(s)
  上原博史、伊夫貴直和、岡部知太、木村孝平、高倉一平、寺本昌司、西村一希、堤岳之、小村和正、平野一、稲元輝生、能見勇人、東治人
- Organizer
  第108回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-19K09702
[Presentation] 転移性腎細胞癌における2nd line Axitinibの治療効果.2019
- Author(s)
  上原博史、伊夫貴直和、藤原裕也、加納陽祐、小林大介、堤岳之、児島彬、小村和正、平野一、稲元輝生、能見勇人、東治人.
- Organizer
  第57回日本癌治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09702
[Presentation] Management of alpha-herpesvirus infection following kidney transplantation: Our experience (7 cases)2019
- Author(s)
  Uehara H, Hirano H, Matsunaga T, Minami K,Kazumasa K, Ibuki N,Inamoto T,Nomi H,Azuma H.
- Organizer
  CAST2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09702
[Presentation] 2型損傷腎を抗凝固・抗血小板薬内服患者に移植し生着を得た献腎移植症例2019
- Author(s)
  上原博史,平野一,岡部知太,木村孝平,寺昌司,高倉一平,西村一希,木下将宏,徳永雄希,中森啓太,小林大介,堤岳之,小村和正,伊夫貴直和,稲元輝生,能見勇人,東治人.
- Organizer
  第55回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-19K09702

1. 東治人 (40231914)

# of Collaborated Projects: 2 results

# of Collaborated Products: 33 results
2. 小村和正 (10789853)

# of Collaborated Projects: 2 results

# of Collaborated Products: 28 results
3. 鈴木実 (00319724)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 小野公二 (90122407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
5. 稲元輝生 (20330087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
6. 松井佑介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Uehara Hirofumi 上原 博史

Research Projects

Research Products

Co-Researchers

Therapeutic effect of boron neutron supplementation therapy with PDL1 antibody for advanced bladder cancer (including metastasis)

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies on a novel immunotherapy for bladder cancer by NAD+Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Importance of Management of Lifestyle-Related Diseases After Kidney Donation to Living Donors2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Usefulness of Dietary Salt Restriction in Kidney Transplant Recipients: Analysis of Blood Pressure Levels Depending on the Differences in the Levels of Salt Intake2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tissue Distribution of Cisplatin by Intra-arterial Infusion Route in Comparison to Systemic Route: Implication to Therapy for Node-positive Bladder Cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nephron-sparing ureteroscopic surgery vs. radical nephroureterectomy: comparable survival-outcomes in upper tract urothelial carcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pattern of expression of microRNA in patients with radiation induced bladder injury2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Optimal Time Point for Evaluation of Response to Pembrolizumab Treatment in Japanese Patients With Metastatic Urothelial Carcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficacy of pembrolizumab and comprehensive CD274/PD-L1 profiles in patients previously treated with chemoradiation therapy as radical treatment in bladder cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic value of the fluctuation in the neutrophil lymphocyte ratio at 6 weeks of pembrolizumab treatment is specific to the clinical response in metastatic urothelial carcinoma.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Unplanned hemodialysis initiation and low geriatric nutritional risk index scores are associated with end-stage renal disease outcomes.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased BUB1B/BUBR1 expression contributes to aberrant DNA repair activity leading to resistance to DNA-damaging agents2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hemodialysis Initiation in Oldest-Old Patients: A Case Series.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Taurodeoxycholic acid and valine reverse obesity-associated augmented alloimmune responses and prolong allograft survival.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Risk Classification for Overall Survival by the Neutrophil-Lymphocyte Ratio and the Number of Metastatic Sites in Patients Treated with Pembrolizumab-A Multicenter Collaborative Study in Japan.2021

Author(s)

Journal Title

DOI

Uehara Hirofumi 上原博史