Katsuyama Akira 勝山彬

Researcher Number	20824709
Other IDs	https://orcid.org/0000-0002-4062-5561
Affiliation (Current)	2024: 北海道大学, 薬学研究院, 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 北海道大学, 薬学研究院, 助教 2018 – 2020: 北海道大学, 薬学研究院, 助教
Review Section/Research Field	Principal Investigator Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / 0801:Pharmaceutical sciences and related fields Except Principal Investigator Medium-sized Section 47:Pharmaceutical sciences and related fields / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
Keywords	Principal Investigator 抗菌薬 / ペプチド / 有機合成化学 / 天然物 / 薬剤耐性菌 / 固相合成 / 抗がん剤 / ケミカルライゲーション / 化合物ライブラリー / 蛍光プローブ / 全合成 / 細胞壁 / 環状ペプチド … More Except Principal Investigator … More 天然物 / 抗菌剤 / 抗菌薬 / ライブラリー / 抗がん剤 / ADC / レジデンスタイム / 創薬化学 / アトロプ異性体 / チオアミド / アミド / 軸不斉 / アトロプ異性 / 活性配座 Less

多段階修飾・構造制御を可能とする新規ペプチドスキャニング法の開発Principal Investigator
- Principal Investigator
  
  勝山彬
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Hokkaido University
Development of a novel Antibody-drug conjugate for cancer therapy
- Principal Investigator
  
  鍛代悠一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Hokkaido University
レジデンスタイム制御構造要素探索とその制御による薬物設計理論の提唱
- Principal Investigator
  
  市川聡
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Hokkaido University
多成分連結型天然物ビルドアップライブラリー法の確立Principal Investigator
- Principal Investigator
  
  勝山彬
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Hokkaido University
ビルドアップライブラリー構築法を用いた薬剤耐性菌リードの創出研究
- Principal Investigator
  
  市川聡
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Hokkaido University
Development of Antibacterial Natural Products DerivativesPrincipal Investigator
- Principal Investigator
  
  Katsuyama Akira
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Hokkaido University
Development of a quick and simple search method for active conformations with amplification and memory of active conformations as the key concept
- Principal Investigator
  
  Ichikawa Satoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Hokkaido University
天然物のフラグメント化を基軸とした抗菌薬の開発研究Principal Investigator
- Principal Investigator
  
  勝山彬
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0801:Pharmaceutical sciences and related fields
- Research Institution
  Hokkaido University

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Discovery of Biologically Optimized Polymyxin Derivatives Facilitated by Peptide Scanning and In Situ Screening Chemistry2023
- Author(s)
  Kaguchi R, Katsuyama A, Sato T, Takahashi S, Horiuchi M, Yokota SI, Ichikawa S
- Journal Title
  
  J Am Chem Soc
  
  Volume: 145 Issue: 6 Pages: 3665-3681
- DOI
  10.1021/jacs.2c12971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19416, KAKENHI-PROJECT-22K15241, KAKENHI-PROJECT-21H03622, KAKENHI-PROJECT-23K23772, KAKENHI-PROJECT-23K24001
[Journal Article] Solid-Phase Total Synthesis of Sandramycin and Its Analogues2023
- Author(s)
  Komatani Yuya、Momosaki Kyoka、Katsuyama Akira、Yamamoto Kazuki、Kaguchi Rintaro、Ichikawa Satoshi
- Journal Title
  
  Organic Letters
  
  Volume: 25 Issue: 3 Pages: 543-548
- DOI
  10.1021/acs.orglett.2c04327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15241, KAKENHI-PROJECT-23K24001
[Journal Article] Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY2022
- Author(s)
  Nakaya T, Yabe M, Mashalidis EH, Sato T, Yamamoto K, Hikiji Y, Katsuyama A, Shinohara M, Minato Y, Takahashi S, Horiuchi M, Yokota SI, Lee SY, Ichikawa S
- Journal Title
  
  Nat Commun
  
  Volume: 13 Issue: 1 Pages: 7575-7575
- DOI
  10.1038/s41467-022-35227-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19416, KAKENHI-PROJECT-21H03622, KAKENHI-PROJECT-23K24001
[Journal Article] Solid-phase Synthesis of Fluorescent Analogues of Park’s Nucleotide, Lipid I and Lipid II2021
- Author(s)
  Akira Katsuyama、Fumika Yakushiji、Satoshi Ichikawa
- Journal Title
  
  Tetrahedron Letters
  
  Volume: - Pages: 153101-153101
- DOI
  10.1016/j.tetlet.2021.153101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16308, KAKENHI-PUBLICLY-20H04757, KAKENHI-PROJECT-19H03345
[Journal Article] Elucidating the Structural Requirement of Uridylpeptide Antibiotics for Antibacterial Activity2020
- Author(s)
  Yuma Terasawa, Chisato Sataka, Toyotaka Sato, Kazuki Yamamoto, Yukari Fukushima, Chie Nakajima, Yasuhiko Suzuki, Akira Katsuyama, Takanori Matsumaru, Fumika Yakushiji, Shin-ichi Yokota, and Satoshi Ichikawa
- Journal Title
  
  J. Med. Chem.
  
  Volume: 63 Issue: 17 Pages: 9803-9827
- DOI
  10.1021/acs.jmedchem.0c00973
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-20H04757, KAKENHI-PROJECT-19H03345, KAKENHI-PROJECT-19K16308
[Journal Article] Total Synthesis of Echinomycin and Its Analogues2020
- Author(s)
  Keita Kojima, Fumika Yakushiji, Akira Katsuyama, and Satoshi Ichikawa, Total Synthesis of Echinomycin and Its Analogues
- Journal Title
  
  Org. Lett
  
  Volume: 22 Issue: 11 Pages: 4217-4221
- DOI
  10.1021/acs.orglett.0c01268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03345, KAKENHI-PROJECT-19K16308
[Journal Article] Total Synthesis of Acaulide and Acaulone A2020
- Author(s)
  Jun Hirabayashi, Fumika Yakushiji, Akira Katsuyama and Satoshi Ichikawa
- Journal Title
  
  Org, Lett
  
  Volume: 22 Issue: 14 Pages: 5545-5549
- DOI
  10.1021/acs.orglett.0c01907
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03345, KAKENHI-PROJECT-19K16308
[Journal Article] A Synthesis Strategy for the Production of a Macrolactone of Gulmirecin A via a Ni(0)-Mediated Reductive Cyclization Reaction2020
- Author(s)
  Shun Kitahata, Akira Katsuyama, Satoshi Ichikawa
- Journal Title
  
  Org. Lett
  
  Volume: 22 Issue: 7 Pages: 2697-2701
- DOI
  10.1021/acs.orglett.0c00665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03345, KAKENHI-PROJECT-19K16308
[Journal Article] Chemical logic of MraY inhibition by antibacterial nucleoside natural products2019
- Author(s)
  Mashalidis Ellene H.、Kaeser Benjamin、Terasawa Yuma、Katsuyama Akira、Kwon Do-Yeon、Lee Kiyoun、Hong Jiyong、Ichikawa Satoshi、Lee Seok-Yong
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 2917-2917
- DOI
  10.1038/s41467-019-10957-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16308, KAKENHI-PROJECT-19H03345
[Journal Article] Structural requirement of tunicamycin V for MraY inhibition2019
- Author(s)
  Kazuki Yamamoto, Akira Katsuyama, Satoshi Ichikawa
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 27 Issue: 8 Pages: 714-1719
- DOI
  10.1016/j.bmc.2019.02.035
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04599, KAKENHI-PROJECT-16H05097, KAKENHI-PROJECT-19K16308, KAKENHI-PROJECT-19H03345
[Journal Article] Synthesis and biological evaluation of a MraY selective analogue of tunicamycins2019
- Author(s)
  Yamamoto Kazuki、Sato Toyotaka、Hikiji Yuta、Katsuyama Akira、Matsumaru Takanori、Yakushiji Fumika、Yokota Shin-Ichi、Ichikawa Satoshi
- Journal Title
  
  Nucleosides, Nucleotides and Nucleic Acids
  
  Volume: 39 Issue: 1-3 Pages: 349-364
- DOI
  10.1080/15257770.2019.1649696
- NAID
  120006887715
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16308, KAKENHI-PROJECT-19K16648
[Journal Article] Total Synthesis of Plusbacin A3 and Its Dideoxy Derivative Using a Solvent-Dependent Diastereodivergent Joulli??Ugi Three-Component Reaction2018
- Author(s)
  Katsuyama Akira、Yakushiji Fumika、Ichikawa Satoshi
- Journal Title
  
  J. Org. Chem.
  
  Volume: 83 Issue: 13 Pages: 7085-7101
- DOI
  10.1021/acs.joc.8b00038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05097, KAKENHI-PROJECT-17J04794, KAKENHI-PROJECT-18H06098
[Presentation] がん細胞標的化シリンゴリン誘導体の合成2022
- Author(s)
  小原天宏、龍見健吾、薬師寺文華、勝山彬、山本一貴、市川聡
- Organizer
  日本薬学会北海道支部第149回例会
- Data Source
  KAKENHI-PROJECT-23K24001
[Presentation] スレオニルジアミノブタン酸スキャニングを用いたポリミキシン耐性菌に有効な創薬リードの創製2022
- Author(s)
  家口凜太郎、勝山彬、佐藤豊孝、堀内基広、横田伸一、市川聡
- Organizer
  第64回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-23K24001
[Presentation] カルコゲン元素置換によるベンズアミド類の2つの結合回転の制御2022
- Author(s)
  永見正太郎，勝山彬，家口凛太郎，市川聡
- Organizer
  第 48 回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-23K24001
[Presentation] ビルドアップ法に基づくコリスチン誘導体の多数供給と評価2022
- Author(s)
  家口凜太郎、勝山彬、喜多俊介、前仲勝実、市川聡
- Organizer
  日本薬学会北海道支部第149回例会
- Data Source
  KAKENHI-PROJECT-23K24001
[Presentation] 人工核酸抗体の開発を指向したサンドラマイシン誘導体の合成研究2022
- Author(s)
  駒谷優弥、百﨑恭佳、勝山彬、山本一貴、市川聡
- Organizer
  第34回万有札幌シンポジウム
- Data Source
  KAKENHI-PROJECT-23K24001
[Presentation] 天然物を模倣したラリアット型ペプチドプラットホームの構築2022
- Author(s)
  中村哲也，勝山彬，市川聡
- Organizer
  第 39 回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-23K24001
[Presentation] 人工核酸抗体の開発を指向したサンドラマイシン誘導体の合成研究2022
- Author(s)
  駒谷優弥、百﨑恭佳、勝山彬、山本一貴、市川聡
- Organizer
  第34回万有札幌シンポジウム
- Data Source
  KAKENHI-PROJECT-22K15241
[Presentation] スレオニルジアミノブタン酸スキャニングを用いたポリミキシン耐性菌に有効な創薬リードの創製2022
- Author(s)
  家口凜太郎、勝山彬、佐藤豊孝、堀内基広、横田伸一、市川聡
- Organizer
  第64回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-22K15241
[Presentation] ビルドアップ法に基づくコリスチン誘導体の多数供給と評価2022
- Author(s)
  家口凜太郎、勝山彬、喜多俊介、前仲勝実、市川聡
- Organizer
  日本薬学会北海道支部第149回例会
- Data Source
  KAKENHI-PROJECT-22K15241
[Presentation] がん細胞標的化プロテアソーム阻害剤の合成2022
- Author(s)
  小原天宏，龍見健吾，河野七海，中島孝平，勝山彬，小川美香子，市川聡
- Organizer
  第 39 回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-23K24001
[Presentation] Echinomycinの全合成2021
- Author(s)
  市川聡, 小嶋啓太, 薬師寺文華, 勝山彬
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K16308
[Presentation] 抗緑膿菌活性を有するウリジルペプチド系天然物の構造活性相関研究2021
- Author(s)
  寺澤侑馬, 佐高千里, 佐藤豊孝, 山本一貴, 勝山彬, 松丸尊紀, 薬師寺文華, 横田伸一, 市川聡
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K16308
[Presentation] グルミレシンAの合成研究2021
- Author(s)
  北畑舜, 勝山彬, 市川聡
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K16308
[Presentation] フラグメント連結戦略を用いたポリミキシン誘導体ライブラリーの簡便かつ迅速な構築2020
- Author(s)
  家口凜太郎, 勝山彬, 佐藤豊孝, 横田伸一, 市川聡
- Organizer
  第32回万有札幌シンポジウム
- Data Source
  KAKENHI-PROJECT-19K16308
[Presentation] ウリジルペプチド系天然物の構造活性相関研究2020
- Author(s)
  寺澤侑馬, 佐高千里, 佐藤豊隆, 山本一貴, 勝山彬, 松丸尊紀, 薬師寺文華, 横田伸一, 市川聡
- Organizer
  反応と合成の進歩 2020 特別企画シンポジウム
- Data Source
  KAKENHI-PROJECT-19K16308
[Presentation] エチノマイシンの全合成と生物活性評価2020
- Author(s)
  小嶋啓太, 薬師寺文華, 勝山彬, 市川聡
- Organizer
  第62回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-19K16308
[Presentation] MurJの作用機序解明を指向したリピドII誘導体の合成2019
- Author(s)
  大川　凌太郎、勝山　彬、薬師寺　文華、市川　聡
- Organizer
  第37回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-19K16308
[Presentation] ペプチドを基盤とするPRC2アロステリック活性化剤の創製研究2019
- Author(s)
  戸子臺泰光、薬師寺文華、仙谷徹、勝山彬、市川聡
- Organizer
  第31回万有札幌シンポジウム
- Data Source
  KAKENHI-PROJECT-19K16308
[Presentation] イリドイド類の全合成研究2019
- Author(s)
  國府田隆司、薬師寺文華、勝山彬、市川聡
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K16308
[Presentation] ナノシスチン Axの全合成2019
- Author(s)
  宮北　大暉、内海　翔平、勝山　彬、薬師寺　文華、市川　聡
- Organizer
  第61回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-19K16308
[Presentation] LANA-ヒストン相互作用阻害剤の創製研究2019
- Author(s)
  石川葵、薬師寺文華、勝山彬、市川聡
- Organizer
  日本薬学会北海道支部第 146 回例会
- Data Source
  KAKENHI-PROJECT-19K16308
[Presentation] Synthetic Studies on Iridoids: Construction of a cis-Fused Cyclopenta[c]pyran Ring via Pauson-Khand Reaction2019
- Author(s)
  Ryuji Kouda, Fumika Yakushiji, Akira Katsuyama, Satoshi Ichikawa
- Organizer
  第27回国際複素環化学会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16308
[Presentation] イリドイド類の合成研究2019
- Author(s)
  國府田隆司、薬師寺文華、勝山彬、市川聡
- Organizer
  日本薬学会北海道支部第 146 回例会
- Data Source
  KAKENHI-PROJECT-19K16308
[Presentation] Total synthesis of plusbacin A32018
- Author(s)
  Akira Katsuyama, Fumika Yakushiji, Satoshi Ichikawa
- Organizer
  256th ACS National Meeting & Exposition, August 22th (2018), Boston, United States
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H06098

1. Ichikawa Satoshi (60333621)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
2. 薬師寺文華 (40548476)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 鍛代悠一 (90756165)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. YOKOTA Shin-ichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. Sato Toyotaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Katsuyama Akira 勝山 彬

Research Projects

Research Products

Co-Researchers

多段階修飾・構造制御を可能とする新規ペプチドスキャニング法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel Antibody-drug conjugate for cancer therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

レジデンスタイム制御構造要素探索とその制御による薬物設計理論の提唱

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

多成分連結型天然物ビルドアップライブラリー法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ビルドアップライブラリー構築法を用いた薬剤耐性菌リードの創出研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Antibacterial Natural Products DerivativesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a quick and simple search method for active conformations with amplification and memory of active conformations as the key concept

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

天然物のフラグメント化を基軸とした抗菌薬の開発研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Discovery of Biologically Optimized Polymyxin Derivatives Facilitated by Peptide Scanning and In Situ Screening Chemistry2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Solid-Phase Total Synthesis of Sandramycin and Its Analogues2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Solid-phase Synthesis of Fluorescent Analogues of Park’s Nucleotide, Lipid I and Lipid II2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elucidating the Structural Requirement of Uridylpeptide Antibiotics for Antibacterial Activity2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Total Synthesis of Echinomycin and Its Analogues2020

Author(s)

Journal Title

Katsuyama Akira 勝山彬