Nasti Alessandro ＮａｓｔｉＡｌｅｓｓａｎｄｒｏ

Researcher Number	20830871
Other IDs	https://orcid.org/0000-0003-2550-2317
Affiliation (Current)	2025: 金沢大学, 医薬保健学総合研究科, 特任准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 金沢大学, 医薬保健学総合研究科, 特任准教授 2021: 金沢大学, 医薬保健学総合研究科, 特任准教授 2020: 金沢大学, 医学系, 博士研究員
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator Combination therapy / Immune response / Pancreatic cancer / Immunotherapy / Proton radiation / adipose tissue (AT) / Immune therapy / SVF / uncultured ADSCs / ADSC / SS / NASH

Proton radiation therapy combined with immunotherapy for enhancing antitumor immune responses in pancreatic cancer murine models.Principal Investigator
- Principal Investigator
  
  Nasti Alessandro
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kanazawa University
Study of liver restorative therapy for a murine nonalcoholic steatohepatitis model by the administration of immune-suppressive fractions of autologous adipose tissue-derived stromal cellsPrincipal Investigator
- Principal Investigator
  
  Nasti Alessandro
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kanazawa University

All 2024 2021 2020

All Journal Article Presentation

[Journal Article] Characterization of adipose tissue-derived stromal cells of mice with nonalcoholic fatty liver disease and their use for liver repair2021
- Author(s)
  Yano M, Honda M, Wada T, Kaneko S, Sakai Y.（ほか17名、19番目）
- Journal Title
  
  Regenerative Therapy
  
  Volume: 18 Pages: 497-507
- DOI
  10.1016/j.reth.2021.11.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-19K08486, KAKENHI-PROJECT-20K08327, KAKENHI-PROJECT-21K07940, KAKENHI-PROJECT-20K17017
[Journal Article] Restorative effect of adipose tissue-derived stem cells on impaired hepatocytes through Notch signaling in non-alcoholic steatohepatitis mice2021
- Author(s)
  Ishida Kosuke、Seki Akihiro、Kawaguchi Kazunori、Nasti Alessandro、Yamato Masatoshi、Inui Hiiro、Komura Takuya、Yamashita Taro、Arai Kuniaki、Yamashita Tatsuya、Mizukoshi Eishiro、Honda Masao、Wada Takashi、Harada Kenichi、Kaneko Shuichi、Sakai Yoshio
- Journal Title
  
  Stem Cell Research
  
  Volume: 54 Pages: 102425-102425
- DOI
  10.1016/j.scr.2021.102425
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-20K08327, KAKENHI-PROJECT-21K07940, KAKENHI-PROJECT-20K17017
[Presentation] Mesenchymal stromal cells improves liver function in NASH by reducing the ER stress induced by hepatic stellate cells in hepatocytes.2024
- Author(s)
  Akihiro Seki, Norihiko Ogawa, Alessandro Nasti, Tuyen Thuy Bich Ho, Yoshio Sakai, Taro Yamashita.
- Organizer
  The 33rd Annual Meeting of the Asian Pacific Association for the Study of the Liver (APASL)
- Data Source
  KAKENHI-PROJECT-20K08327
[Presentation] Jagged1 ON ADIPOSE TISSUE-DERIVED STROMAL / STEM CELLS IS INVOLVED IN THE RESTORATIVE EFFECT ON MURINE NON-ALCOHOLIC STEATOHEPATITIS.2021
- Author(s)
  Kosuke Ishida, Yoshio Sakai, Akihiro Seki, Kazunori Kawaguchi, Alessandro Nasti, Takashi Wada and Shuichi Kaneko
- Organizer
  AASLD, The Liver Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08327
[Presentation] Restorative effect of adipose tissue-derived mesenchymal stem cells towards impaired hepatocytes via Notch signaling in a murine model of non-alcoholic steatohepatitis mice2021
- Author(s)
  Kosuke Ishida, Yoshio Sakai, Akihiro Seki, Kazunori Kawaguchi, Alessandro Nasti, Hiiro Inui, Takashi Wada, Shuichi Kaneko
- Organizer
  The 44th Annual Meeting of the Molecular Biology Society of Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08327
[Presentation] Adipose tissue derived stromal/stem cells suppress the hepatocyte apoptosis by restoring the Atf6 pathway activity in NASH mice.2020
- Author(s)
  Masatoshi Yamato, Yoshio Sakai, Hiiro Inui, Akihiro Seki, Alessandro Nasti, Kosuke Ishida, Tuyen Thuy Bich Ho, Kazunori Kawaguchi, Takashi Wada, Shuichi Kaneko
- Organizer
  AASLD, The Liver Meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08327
[Presentation] Investigator-initiated clinical trial of autologous adipose tissue-derived regenerative (stem) cells therapy for steatohepatitis-related cirrhosis.2020
- Author(s)
  Yoshio Sakai, Shinya Fukunishi, Masayuki Takamura, Oto Inoue, Soichiro Usui, Shinichiro Takashima, Kazunori Kawaguchi, Akihiro Seki, Akira Asai, Yusuke Tsuchimoto, Alessandro Nasti, Tuyen Thuy Bich Ho, Kazuhide Higuchi, Shuichi Kaneko
- Organizer
  AASLD, The Liver Meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08327
[Presentation] Therapy with adipose tissue-derived mesenchymal stromal/stem cells for NASH mice enhance the activation of Notch signaling and alleviate apoptosis in hepatocytes.2020
- Author(s)
  Kosuke Ishida, Yoshio Sakai, Akihiro Seki, Kazunori Kawaguchi, Alessandro Nasti, Hiiro Inui, Takashi Wada, Shuichi Kaneko
- Organizer
  AASLD, The Liver Meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08327
[Presentation] Adipose tissue-derived stromal cells of steatohepatitis mice are useful for treatment of fibrosis-progressive NASH2020
- Author(s)
  Akihiro Seki, Yoshio Sakai, Alessandro Nasti, Masatoshi Yamato, Kosuke Ishida, Hiiro Inui, Tuyen Thuy Bich Ho, Kazunori Kawaguchi, Takashi Wada, Shuichi Kaneko
- Organizer
  AASLD, The Liver Meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08327

1. 関晃裕 (00733859)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. 酒井佳夫 (80401925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. 本多政夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Nasti Alessandro Ｎａｓｔｉ Ａｌｅｓｓａｎｄｒｏ

Research Projects

Research Products

Co-Researchers

Proton radiation therapy combined with immunotherapy for enhancing antitumor immune responses in pancreatic cancer murine models.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of liver restorative therapy for a murine nonalcoholic steatohepatitis model by the administration of immune-suppressive fractions of autologous adipose tissue-derived stromal cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Characterization of adipose tissue-derived stromal cells of mice with nonalcoholic fatty liver disease and their use for liver repair2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Restorative effect of adipose tissue-derived stem cells on impaired hepatocytes through Notch signaling in non-alcoholic steatohepatitis mice2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] Mesenchymal stromal cells improves liver function in NASH by reducing the ER stress induced by hepatic stellate cells in hepatocytes.2024

Author(s)

Organizer

Data Source

[Presentation] Jagged1 ON ADIPOSE TISSUE-DERIVED STROMAL / STEM CELLS IS INVOLVED IN THE RESTORATIVE EFFECT ON MURINE NON-ALCOHOLIC STEATOHEPATITIS.2021

Author(s)

Organizer

Data Source

[Presentation] Restorative effect of adipose tissue-derived mesenchymal stem cells towards impaired hepatocytes via Notch signaling in a murine model of non-alcoholic steatohepatitis mice2021

Author(s)

Organizer

Data Source

[Presentation] Adipose tissue derived stromal/stem cells suppress the hepatocyte apoptosis by restoring the Atf6 pathway activity in NASH mice.2020

Author(s)

Organizer

Data Source

[Presentation] Investigator-initiated clinical trial of autologous adipose tissue-derived regenerative (stem) cells therapy for steatohepatitis-related cirrhosis.2020

Author(s)

Organizer

Data Source

[Presentation] Therapy with adipose tissue-derived mesenchymal stromal/stem cells for NASH mice enhance the activation of Notch signaling and alleviate apoptosis in hepatocytes.2020

Author(s)

Organizer

Data Source

[Presentation] Adipose tissue-derived stromal cells of steatohepatitis mice are useful for treatment of fibrosis-progressive NASH2020

Author(s)

Organizer

Data Source

Nasti Alessandro ＮａｓｔｉＡｌｅｓｓａｎｄｒｏ