NUMATA GENRI 沼田玄理

Researcher Number	20834188
Other IDs	https://orcid.org/0000-0001-8155-5304
Affiliation (Current)	2025: 東京大学, アイソトープ総合センター, 特任助教 2025: 東京大学, 医学部附属病院, 届出研究員
Affiliation (based on the past Project Information) *help	2025: 東京大学, アイソトープ総合センター, 特任助教 2024: 東京大学, 医学部附属病院, 特任助教 2023: 東京大学, アイソトープ総合センター, 特任助教 2022: 東京大学, 医学部附属病院, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related Except Principal Investigator Basic Section 53020:Cardiology-related
Keywords	Principal Investigator レチノイド / 内皮間葉転換 / 強皮症肺高血圧 / 肺動脈性肺高血圧 / 肺高血圧 Except Principal Investigator 肥大シグナル / 細胞死シグナル / 核内シグナル / 心不全 / GAPDH

GAPDH細胞内局在と関連した新規心不全メカニズムの解明Principal Investigator
- Principal Investigator
  
  沼田玄理
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  The University of Tokyo
The role of GAPDH in the deveopment of cardiovascular disease
- Principal Investigator
  
  瀧本英樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  The University of Tokyo
レチノイドX受容体は内皮間葉転換を介して強皮症関連肺高血圧症を改善するかPrincipal Investigator
- Principal Investigator
  
  沼田玄理
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  The University of Tokyo

All 2023 2022

All Journal Article Presentation

[Journal Article] NLRP3 Inflammasome Activation Through Heart-Brain Interaction Initiates Cardiac Inflammation and Hypertrophy During Pressure Overload2023
- Author(s)
  Higashikuni Yasutomi、Liu Wenhao、Numata Genri、Tanaka Kimie、Fukuda Daiju、Tanaka Yu、Hirata Yoichiro、Imamura Teruhiko、Takimoto Eiki、Komuro Issei、Sata Masataka
- Journal Title
  
  Circulation
  
  Volume: 147 Issue: 4 Pages: 338-355
- DOI
  10.1161/circulationaha.122.060860
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16130, KAKENHI-PROJECT-23K24330
[Journal Article] Prognostic value of follow-up vasoreactivity test in pulmonary arterial hypertension2023
- Author(s)
  Ishii, S. Hatano, M. Maki, H. Minatsuki, S. Saito, A. Yagi, H. Shimbo, M. Soma, K. Numata, G. Fujiwara, T. Takeda, N. Komuro, I.
- Journal Title
  
  Journal of Cardiology
  
  Volume: - Issue: 1 Pages: 69-75
- DOI
  10.1016/j.jjcc.2023.01.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08276, KAKENHI-PROJECT-22K16130, KAKENHI-PROJECT-21K16110, KAKENHI-PROJECT-20K08398
[Journal Article] Tie2-Cre-Induced Inactivation of Non-Nuclear Estrogen Receptor-α Signaling Abrogates Estrogen Protection Against Vascular Injury2023
- Author(s)
  Liu Pang-Yen、Fukuma Nobuaki、Hiroi Yukio、Kunita Akiko、Tokiwa Hiroyuki、Ueda Kazutaka、Kariya Taro、Numata Genri、Adachi Yusuke、Tajima Miyu、Toyoda Masayuki、Li Yuxin、Noma Kensuke、Harada Mutsuo、Toko Haruhiro、Ushiku Tetsuo、Kanai Yoshimitsu、Takimoto Eiki、Liao James K.、Komuro Issei
- Journal Title
  
  JACC: Basic to Translational Science
  
  Volume: 8 Issue: 1 Pages: 55-67
- DOI
  10.1016/j.jacbts.2022.07.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16064, KAKENHI-PROJECT-22K16097, KAKENHI-PROJECT-22K16130, KAKENHI-PROJECT-20K07422, KAKENHI-PROJECT-22K08515, KAKENHI-PROJECT-21H02908, KAKENHI-PROJECT-20K07739
[Journal Article] Beiging of perivascular adipose tissue regulates its inflammation and vascular remodeling2022
- Author(s)
  Adachi Yusuke、Ueda Kazutaka、Nomura Seitaro、Ito Kaoru、Katoh Manami、Katagiri Mikako、Yamada Shintaro、Hashimoto Masaki、Zhai Bowen、Numata Genri、Otani Akira、Hinata Munetoshi、Hiraike Yuta、Waki Hironori、Takeda Norifumi、Morita Hiroyuki、Ushiku Tetsuo、Yamauchi Toshimasa、Takimoto Eiki、Komuro Issei
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 5117-5117
- DOI
  10.1038/s41467-022-32658-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16097, KAKENHI-PROJECT-22K16130, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19K17976, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-22H00471, KAKENHI-PROJECT-21H02908
[Journal Article] A pacing-controlled protocol for frequency-diastolic relations distinguishes diastolic dysfunction specific to a mouse HFpEF model2022
- Author(s)
  Numata Genri、Takimoto Eiki、Kariya Taro、Adachi Yusuke、Tokiwa Hiroyuki、Toyoda Masayuki、Mafune Ryo、Saito Yoshihiro、Nakamura Shun、Ueda Kazutaka、Ikeda Yuichi、Komuro Issei
- Journal Title
  
  American Journal of Physiology-Heart and Circulatory Physiology
  
  Volume: 323 Issue: 3 Pages: H523-H527
- DOI
  10.1152/ajpheart.00241.2022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16064, KAKENHI-PROJECT-22K16097, KAKENHI-PROJECT-22K16130, KAKENHI-PROJECT-22KJ1202, KAKENHI-PROJECT-21H02908
[Journal Article] Endoplasmic reticulum stress-activated nuclear factor-kappa B signaling pathway induces the upregulation of cardiomyocyte dopamine D1 receptor in heart failure2022
- Author(s)
  Shun Nakamura, Genri Numata, Toshihiro Yamaguchi, Hiroyuki Tokiwa, Yasutomi Higashikuni, Seitaro Nomura, Tetsuo Sasano, Eiki Takimoto, Issei Komuro
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 637 Pages: 247-253
- DOI
  10.1016/j.bbrc.2022.11.031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08098, KAKENHI-PROJECT-22K16064, KAKENHI-PROJECT-22K16130, KAKENHI-PROJECT-21H05045, KAKENHI-PROJECT-19H03649, KAKENHI-PROJECT-22H00471, KAKENHI-PROJECT-22KJ1202
[Journal Article] Cyclic GMP and PKG Signaling in Heart Failure2022
- Author(s)
  Numata Genri、Takimoto Eiki
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 13
- DOI
  10.3389/fphar.2022.792798
- Data Source
  KAKENHI-PROJECT-22K16130
[Presentation] RXR αは p53 による内皮間葉転換を介して肺高血圧を改善する2023
- Author(s)
  Genri Numata
- Organizer
  日本肺高血圧・肺循環学会
- Data Source
  KAKENHI-PROJECT-22K16130
[Presentation] Role of Beta 1 Adrenergic Receptor in Acute Heart Failure: Phenotype Analysis of Cardiomyocyte-Specific Knockout Mice2023
- Author(s)
  Genri Numata
- Organizer
  第87回日本循環器学会学術集会(JCS2023)
- Data Source
  KAKENHI-PROJECT-22K16130

1. 瀧本英樹 (20709513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 和田洋一郎 (10322033)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 川村猛 (70306835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 安達裕助

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 常盤洋之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 武田憲文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 東邦康智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 山口敏弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NUMATA GENRI 沼田 玄理

Research Projects

Research Products

Co-Researchers

GAPDH細胞内局在と関連した新規心不全メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of GAPDH in the deveopment of cardiovascular disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

レチノイドX受容体は内皮間葉転換を介して強皮症関連肺高血圧症を改善するかPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] NLRP3 Inflammasome Activation Through Heart-Brain Interaction Initiates Cardiac Inflammation and Hypertrophy During Pressure Overload2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prognostic value of follow-up vasoreactivity test in pulmonary arterial hypertension2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tie2-Cre-Induced Inactivation of Non-Nuclear Estrogen Receptor-α Signaling Abrogates Estrogen Protection Against Vascular Injury2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Beiging of perivascular adipose tissue regulates its inflammation and vascular remodeling2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A pacing-controlled protocol for frequency-diastolic relations distinguishes diastolic dysfunction specific to a mouse HFpEF model2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Endoplasmic reticulum stress-activated nuclear factor-kappa B signaling pathway induces the upregulation of cardiomyocyte dopamine D1 receptor in heart failure2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cyclic GMP and PKG Signaling in Heart Failure2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] RXR αは p53 による内皮間葉転換を介して肺高血圧を改善する2023

Author(s)

Organizer

Data Source

[Presentation] Role of Beta 1 Adrenergic Receptor in Acute Heart Failure: Phenotype Analysis of Cardiomyocyte-Specific Knockout Mice2023

Author(s)

Organizer

Data Source

NUMATA GENRI 沼田玄理